메뉴 건너뛰기




Volumn 89, Issue 9, 2010, Pages 712-722

Dexamethasone enhances the norepinephrine-induced ERK/MAPK intracellular pathway possibly via dysregulation of the α2-adrenergic receptor: Implications for antidepressant drug mechanism of action

Author keywords

CREB; ERK MAPK; Glucocorticoids; Norepinephrine; Plasticity; arrestin

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; BETA ARRESTIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DESIPRAMINE; DEXAMETHASONE; GLUCOCORTICOID; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; NORADRENALIN; PROTEIN C FOS; STRESS ACTIVATED PROTEIN KINASE; YOHIMBINE;

EID: 77954953004     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejcb.2010.05.002     Document Type: Article
Times cited : (29)

References (43)
  • 1
    • 0027340385 scopus 로고
    • Gi-mediated activation of the p21ras-mitogen-activated protein kinase pathway by alpha 2-adrenergic receptors expressed in fibroblasts
    • Alblas J., van Corven E.J., Hordijk P.L., Milligan G., Moolenaar W.H. Gi-mediated activation of the p21ras-mitogen-activated protein kinase pathway by alpha 2-adrenergic receptors expressed in fibroblasts. J Biol Chem 1993, 268:22235-22238.
    • (1993) J Biol Chem , vol.268 , pp. 22235-22238
    • Alblas, J.1    van Corven, E.J.2    Hordijk, P.L.3    Milligan, G.4    Moolenaar, W.H.5
  • 2
    • 0025720735 scopus 로고
    • The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
    • Angel P., Karin M. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim Biophys Acta 1991, 1072:129-157.
    • (1991) Biochim Biophys Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 3
    • 0033970533 scopus 로고    scopus 로고
    • Dual specificity phosphatases: a gene family for control of MAP kinase function
    • Camps M., Nichols A., Arkinstall S. Dual specificity phosphatases: a gene family for control of MAP kinase function. Faseb J 2000, 14:6-16.
    • (2000) Faseb J , vol.14 , pp. 6-16
    • Camps, M.1    Nichols, A.2    Arkinstall, S.3
  • 4
    • 0034618845 scopus 로고    scopus 로고
    • Axonal regeneration from CNS neurons in the cerebellum and brainstem of adult rats: correlation with the patterns of expression and distribution of messenger RNAs for L1, CHL1, c-jun and growth-associated protein-43
    • Chaisuksunt V., Zhang Y., Anderson P.N., Campbell G., Vaudano E., Schachner M., Lieberman A.R. Axonal regeneration from CNS neurons in the cerebellum and brainstem of adult rats: correlation with the patterns of expression and distribution of messenger RNAs for L1, CHL1, c-jun and growth-associated protein-43. Neuroscience 2000, 100:87-108.
    • (2000) Neuroscience , vol.100 , pp. 87-108
    • Chaisuksunt, V.1    Zhang, Y.2    Anderson, P.N.3    Campbell, G.4    Vaudano, E.5    Schachner, M.6    Lieberman, A.R.7
  • 5
    • 33748156957 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase pathway: an emerging promising target for mood stabilizers
    • Chen G., Manji H.K. The extracellular signal-regulated kinase pathway: an emerging promising target for mood stabilizers. Curr Opin Psychiatry 2006, 19:313-323.
    • (2006) Curr Opin Psychiatry , vol.19 , pp. 313-323
    • Chen, G.1    Manji, H.K.2
  • 6
    • 0030908655 scopus 로고    scopus 로고
    • Subtype-specific intracellular trafficking of alpha2-adrenergic receptors
    • Daunt D.A., Hurt C., Hein L., Kallio J., Feng F., Kobilka B.K. Subtype-specific intracellular trafficking of alpha2-adrenergic receptors. Mol Pharmacol 1997, 51:711-720.
    • (1997) Mol Pharmacol , vol.51 , pp. 711-720
    • Daunt, D.A.1    Hurt, C.2    Hein, L.3    Kallio, J.4    Feng, F.5    Kobilka, B.K.6
  • 7
    • 0033574525 scopus 로고    scopus 로고
    • Role of arrestins in endocytosis and signaling of alpha2-adrenergic receptor subtypes
    • DeGraff J.L., Gagnon A.W., Benovic J.L., Orsini M.J. Role of arrestins in endocytosis and signaling of alpha2-adrenergic receptor subtypes. J Biol Chem 1999, 274:11253-11259.
    • (1999) J Biol Chem , vol.274 , pp. 11253-11259
    • DeGraff, J.L.1    Gagnon, A.W.2    Benovic, J.L.3    Orsini, M.J.4
  • 8
    • 0028329953 scopus 로고
    • JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
    • Derijard B., Hibi M., Wu I.H., Barrett T., Su B., Deng T., Karin M., Davis R.J. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 1994, 76:1025-1037.
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Derijard, B.1    Hibi, M.2    Wu, I.H.3    Barrett, T.4    Su, B.5    Deng, T.6    Karin, M.7    Davis, R.J.8
  • 9
    • 0032576396 scopus 로고    scopus 로고
    • Increased temporal cortex CREB concentrations and antidepressant treatment in major depression
    • Dowlatshahi D., MacQueen G.M., Wang J.F., Young L.T. Increased temporal cortex CREB concentrations and antidepressant treatment in major depression. Lancet 1998, 352:1754-1755.
    • (1998) Lancet , vol.352 , pp. 1754-1755
    • Dowlatshahi, D.1    MacQueen, G.M.2    Wang, J.F.3    Young, L.T.4
  • 10
    • 33847308098 scopus 로고    scopus 로고
    • A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment
    • Duman C.H., Schlesinger L., Kodama M., Russell D.S., Duman R.S. A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment. Biol Psychiatry 2007, 61:661-670.
    • (2007) Biol Psychiatry , vol.61 , pp. 661-670
    • Duman, C.H.1    Schlesinger, L.2    Kodama, M.3    Russell, D.S.4    Duman, R.S.5
  • 11
    • 0033232499 scopus 로고    scopus 로고
    • Neural plasticity to stress and antidepressant treatment
    • Duman R.S., Malberg J., Thome J. Neural plasticity to stress and antidepressant treatment. Biol Psychiatry 1999, 46:1181-1191.
    • (1999) Biol Psychiatry , vol.46 , pp. 1181-1191
    • Duman, R.S.1    Malberg, J.2    Thome, J.3
  • 12
    • 0037338519 scopus 로고    scopus 로고
    • Abnormal expression and functional characteristics of cyclic adenosine monophosphate response element binding protein in postmortem brain of suicide subjects
    • Dwivedi Y., Rao J.S., Rizavi H.S., Kotowski J., Conley R.R., Roberts R.C., Tamminga C.A., Pandey G.N. Abnormal expression and functional characteristics of cyclic adenosine monophosphate response element binding protein in postmortem brain of suicide subjects. Arch Gen Psychiatry 2003, 60:273-282.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 273-282
    • Dwivedi, Y.1    Rao, J.S.2    Rizavi, H.S.3    Kotowski, J.4    Conley, R.R.5    Roberts, R.C.6    Tamminga, C.A.7    Pandey, G.N.8
  • 13
    • 0035020808 scopus 로고    scopus 로고
    • Reduced activation and expression of ERK1/2 MAP kinase in the post-mortem brain of depressed suicide subjects
    • Dwivedi Y., Rizavi H.S., Roberts R.C., Conley R.C., Tamminga C.A., Pandey G.N. Reduced activation and expression of ERK1/2 MAP kinase in the post-mortem brain of depressed suicide subjects. J Neurochem 2001, 77:916-928.
    • (2001) J Neurochem , vol.77 , pp. 916-928
    • Dwivedi, Y.1    Rizavi, H.S.2    Roberts, R.C.3    Conley, R.C.4    Tamminga, C.A.5    Pandey, G.N.6
  • 14
    • 77954075814 scopus 로고    scopus 로고
    • Aberrant extracellular signal-regulated kinase (ERK)1/2 signalling in suicide brain: role of ERK kinase 1 (MEK1)
    • Dwivedi Y., Rizavi H.S., Zhang H., Roberts R.C., Conley R.R., Pandey G.N. Aberrant extracellular signal-regulated kinase (ERK)1/2 signalling in suicide brain: role of ERK kinase 1 (MEK1). Int J Neuropsychopharmacol 2009, 12:1337-1354.
    • (2009) Int J Neuropsychopharmacol , vol.12 , pp. 1337-1354
    • Dwivedi, Y.1    Rizavi, H.S.2    Zhang, H.3    Roberts, R.C.4    Conley, R.R.5    Pandey, G.N.6
  • 15
    • 0026469352 scopus 로고
    • Subtype-selective desensitization of alpha 2-adrenergic receptors. Different mechanisms control short and long term agonist-promoted desensitization of alpha 2C10, alpha 2C4, and alpha 2C2
    • Eason M.G., Liggett S.B. Subtype-selective desensitization of alpha 2-adrenergic receptors. Different mechanisms control short and long term agonist-promoted desensitization of alpha 2C10, alpha 2C4, and alpha 2C2. J Biol Chem 1992, 267:25473-25479.
    • (1992) J Biol Chem , vol.267 , pp. 25473-25479
    • Eason, M.G.1    Liggett, S.B.2
  • 16
    • 0142090726 scopus 로고    scopus 로고
    • Impairments of ERK signal transduction in the brain in a rat model of depression induced by neonatal exposure of clomipramine
    • Feng P., Guan Z., Yang X., Fang J. Impairments of ERK signal transduction in the brain in a rat model of depression induced by neonatal exposure of clomipramine. Brain Res 2003, 991:195-205.
    • (2003) Brain Res , vol.991 , pp. 195-205
    • Feng, P.1    Guan, Z.2    Yang, X.3    Fang, J.4
  • 18
    • 0028322364 scopus 로고
    • Chronic electroconvulsive seizure (ECS) treatment results in expression of a long-lasting AP-1 complex in brain with altered composition and characteristics
    • Hope B.T., Kelz M.B., Duman R.S., Nestler E.J. Chronic electroconvulsive seizure (ECS) treatment results in expression of a long-lasting AP-1 complex in brain with altered composition and characteristics. J Neurosci 1994, 14:4318-4328.
    • (1994) J Neurosci , vol.14 , pp. 4318-4328
    • Hope, B.T.1    Kelz, M.B.2    Duman, R.S.3    Nestler, E.J.4
  • 20
    • 0025015647 scopus 로고
    • Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone
    • Jonat C., Rahmsdorf H.J., Park K.K., Cato A.C., Gebel S., Ponta H., Herrlich P. Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone. Cell 1990, 62:1189-1204.
    • (1990) Cell , vol.62 , pp. 1189-1204
    • Jonat, C.1    Rahmsdorf, H.J.2    Park, K.K.3    Cato, A.C.4    Gebel, S.5    Ponta, H.6    Herrlich, P.7
  • 21
    • 0026011644 scopus 로고
    • Alpha 2-adrenergic receptor stimulation of phospholipase A2 and of adenylate cyclase in transfected Chinese hamster ovary cells is mediated by different mechanisms
    • Jones S.B., Halenda S.P., Bylund D.B. Alpha 2-adrenergic receptor stimulation of phospholipase A2 and of adenylate cyclase in transfected Chinese hamster ovary cells is mediated by different mechanisms. Mol Pharmacol 1991, 39:239-245.
    • (1991) Mol Pharmacol , vol.39 , pp. 239-245
    • Jones, S.B.1    Halenda, S.P.2    Bylund, D.B.3
  • 22
    • 33747754751 scopus 로고    scopus 로고
    • Monoaminergic neuronal activity up-regulates BDNF synthesis in cultured neonatal rat astrocytes
    • Juric D.M., Miklic S., Carman-Krzan M. Monoaminergic neuronal activity up-regulates BDNF synthesis in cultured neonatal rat astrocytes. Brain Res 2006, 1108:54-62.
    • (2006) Brain Res , vol.1108 , pp. 54-62
    • Juric, D.M.1    Miklic, S.2    Carman-Krzan, M.3
  • 23
    • 0037126628 scopus 로고    scopus 로고
    • Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1
    • Kassel O., Sancono A., Kratzschmar J., Kreft B., Stassen M., Cato A. Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1. EMBO J 2001, 20:7108-7116.
    • (2001) EMBO J , vol.20 , pp. 7108-7116
    • Kassel, O.1    Sancono, A.2    Kratzschmar, J.3    Kreft, B.4    Stassen, M.5    Cato, A.6
  • 24
    • 33846807548 scopus 로고    scopus 로고
    • Differential activation of CREB by Akt1 and Akt2
    • Kato S., Ding J., Du K. Differential activation of CREB by Akt1 and Akt2. Biochem Biophys Res Commun 2007, 354:1061-1066.
    • (2007) Biochem Biophys Res Commun , vol.354 , pp. 1061-1066
    • Kato, S.1    Ding, J.2    Du, K.3
  • 25
    • 5644293601 scopus 로고    scopus 로고
    • Dexamethasone inhibits proliferation of adult hippocampal neurogenesis in vivo and in vitro
    • Kim J.B., Ju J.Y., Kim J.H., Kim T.Y., Yang B.H., Lee Y.S., Son H. Dexamethasone inhibits proliferation of adult hippocampal neurogenesis in vivo and in vitro. Brain Res 2004, 1027:1-10.
    • (2004) Brain Res , vol.1027 , pp. 1-10
    • Kim, J.B.1    Ju, J.Y.2    Kim, J.H.3    Kim, T.Y.4    Yang, B.H.5    Lee, Y.S.6    Son, H.7
  • 26
    • 26944460403 scopus 로고    scopus 로고
    • Antidepressants and prolonged stress in rats modulate CAM-L1, laminin, and pCREB, implicated in neuronal plasticity
    • Laifenfeld D., Karry R., Grauer E., Klein E., Ben-Shachar D. Antidepressants and prolonged stress in rats modulate CAM-L1, laminin, and pCREB, implicated in neuronal plasticity. Neurobiol Dis 2005.
    • (2005) Neurobiol Dis
    • Laifenfeld, D.1    Karry, R.2    Grauer, E.3    Klein, E.4    Ben-Shachar, D.5
  • 27
    • 16844380161 scopus 로고    scopus 로고
    • Alterations in cell adhesion molecule L1 and functionally related genes in major depression: a postmortem study
    • Laifenfeld D., Karry R., Klein E., Ben-Shachar D. Alterations in cell adhesion molecule L1 and functionally related genes in major depression: a postmortem study. Biol Psychiatry 2005, 57:716-725.
    • (2005) Biol Psychiatry , vol.57 , pp. 716-725
    • Laifenfeld, D.1    Karry, R.2    Klein, E.3    Ben-Shachar, D.4
  • 28
    • 0036892117 scopus 로고    scopus 로고
    • Norepinephrine alters the expression of genes involved in neuronal sprouting and differentiation: relevance for major depression and antidepressant mechanisms
    • Laifenfeld D., Klein E., Ben-Shachar D. Norepinephrine alters the expression of genes involved in neuronal sprouting and differentiation: relevance for major depression and antidepressant mechanisms. J Neurochem 2002, 83:1054-1064.
    • (2002) J Neurochem , vol.83 , pp. 1054-1064
    • Laifenfeld, D.1    Klein, E.2    Ben-Shachar, D.3
  • 29
    • 0034671366 scopus 로고    scopus 로고
    • Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
    • Malberg J.E., Eisch A.J., Nestler E.J., Duman R.S. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 2000, 20:9104-9110.
    • (2000) J Neurosci , vol.20 , pp. 9104-9110
    • Malberg, J.E.1    Eisch, A.J.2    Nestler, E.J.3    Duman, R.S.4
  • 30
    • 0030903789 scopus 로고    scopus 로고
    • Regulation of c-Fos and NGF1-A by antidepressant treatments
    • Morinobu S., Strausbaugh H., Terwilliger R., Duman R.S. Regulation of c-Fos and NGF1-A by antidepressant treatments. Synapse 1997, 25:313-320.
    • (1997) Synapse , vol.25 , pp. 313-320
    • Morinobu, S.1    Strausbaugh, H.2    Terwilliger, R.3    Duman, R.S.4
  • 33
    • 0033152333 scopus 로고    scopus 로고
    • The mitogen-activated protein kinase cascade couples PKA and PKC to cAMP response element binding protein phosphorylation in area CA1 of hippocampus
    • Roberson E.D., English J.D., Adams J.P., Selcher J.C., Kondratick C., Sweatt J.D. The mitogen-activated protein kinase cascade couples PKA and PKC to cAMP response element binding protein phosphorylation in area CA1 of hippocampus. J Neurosci 1999, 19:4337-4348.
    • (1999) J Neurosci , vol.19 , pp. 4337-4348
    • Roberson, E.D.1    English, J.D.2    Adams, J.P.3    Selcher, J.C.4    Kondratick, C.5    Sweatt, J.D.6
  • 35
    • 33644596087 scopus 로고    scopus 로고
    • Signaling pathways regulating gene expression, neuroplasticity, and neurotrophic mechanisms in the action of antidepressants: a critical overview
    • Tardito D., Perez J., Tiraboschi E., Musazzi L., Racagni G., Popoli M. Signaling pathways regulating gene expression, neuroplasticity, and neurotrophic mechanisms in the action of antidepressants: a critical overview. Pharmacol Rev 2006, 58:115-134.
    • (2006) Pharmacol Rev , vol.58 , pp. 115-134
    • Tardito, D.1    Perez, J.2    Tiraboschi, E.3    Musazzi, L.4    Racagni, G.5    Popoli, M.6
  • 37
    • 1642326111 scopus 로고    scopus 로고
    • Enhancement of MEK/ERK signaling promotes glucocorticoid resistance in CD4+ T cells
    • Tsitoura D.C., Rothman P.B. Enhancement of MEK/ERK signaling promotes glucocorticoid resistance in CD4+ T cells. J Clin Invest 2004, 113:619-627.
    • (2004) J Clin Invest , vol.113 , pp. 619-627
    • Tsitoura, D.C.1    Rothman, P.B.2
  • 38
    • 33744764926 scopus 로고    scopus 로고
    • MAP kinase pathway-dependent phosphorylation of the L1-CAM ankyrin binding site regulates neuronal growth
    • Whittard J.D., Sakurai T., Cassella M.R., Gazdoiu M., Felsenfeld D.P. MAP kinase pathway-dependent phosphorylation of the L1-CAM ankyrin binding site regulates neuronal growth. Mol Biol Cell 2006, 17:2696-2706.
    • (2006) Mol Biol Cell , vol.17 , pp. 2696-2706
    • Whittard, J.D.1    Sakurai, T.2    Cassella, M.R.3    Gazdoiu, M.4    Felsenfeld, D.P.5
  • 39
    • 0028812317 scopus 로고
    • Protein kinase C mediates activation of nuclear cAMP response element-binding protein (CREB) in B lymphocytes stimulated through surface Ig
    • Xie H., Rothstein T.L. Protein kinase C mediates activation of nuclear cAMP response element-binding protein (CREB) in B lymphocytes stimulated through surface Ig. J Immunol 1995, 154:1717-1723.
    • (1995) J Immunol , vol.154 , pp. 1717-1723
    • Xie, H.1    Rothstein, T.L.2
  • 40
    • 53249100299 scopus 로고    scopus 로고
    • Norepinephrine-glucocorticoids interaction does not annul the opposite effects of the individual treatments on cellular plasticity in neuroblastoma cells
    • Yaniv S.P., Ben-Shachar D., Klein E. Norepinephrine-glucocorticoids interaction does not annul the opposite effects of the individual treatments on cellular plasticity in neuroblastoma cells. Eur J Pharmacol 2008, 596:14-24.
    • (2008) Eur J Pharmacol , vol.596 , pp. 14-24
    • Yaniv, S.P.1    Ben-Shachar, D.2    Klein, E.3
  • 41
    • 1842426600 scopus 로고    scopus 로고
    • Differential effects of corticosterone and dexamethasone on hippocampal neurogenesis in vitro
    • Yu I.T., Lee S.H., Lee Y.S., Son H. Differential effects of corticosterone and dexamethasone on hippocampal neurogenesis in vitro. Biochem Biophys Res Commun 2004, 317:484-490.
    • (2004) Biochem Biophys Res Commun , vol.317 , pp. 484-490
    • Yu, I.T.1    Lee, S.H.2    Lee, Y.S.3    Son, H.4
  • 42
    • 0032587931 scopus 로고    scopus 로고
    • Alpha1-adrenoceptor subtypes
    • Zhong H., Minneman K.P. Alpha1-adrenoceptor subtypes. Eur J Pharmacol 1999, 375:261-276.
    • (1999) Eur J Pharmacol , vol.375 , pp. 261-276
    • Zhong, H.1    Minneman, K.P.2
  • 43
    • 0029917011 scopus 로고    scopus 로고
    • Linearization of the Bradford protein assay increases its sensitivity: theoretical and experimental studies
    • Zor T., Selinger Z. Linearization of the Bradford protein assay increases its sensitivity: theoretical and experimental studies. Anal Biochem 1996, 236:302-308.
    • (1996) Anal Biochem , vol.236 , pp. 302-308
    • Zor, T.1    Selinger, Z.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.