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Volumn 1, Issue 3, 2010, Pages 220-229

Quantitative Temporal Profiles of Penumbra and Infarction During Permanent Middle Cerebral Artery Occlusion in Rats

Author keywords

Acute stroke; Apparent diffusion coefficient; Cerebral blood flow; Diagnosis; Magnetic resonance imaging

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN INFARCTION; BRAIN SIZE; BRAIN TISSUE; CONTROLLED STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; SUTURE;

EID: 77954952157     PISSN: 18684483     EISSN: 1868601X     Source Type: Journal    
DOI: 10.1007/s12975-010-0032-6     Document Type: Article
Times cited : (38)

References (44)
  • 1
    • 33845298309 scopus 로고    scopus 로고
    • Magnetic resonance imaging profiles predict clinical response to early reperfusion: The diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study
    • Albers GW, Thijs VN, Wechsler L, Kemp S, Schlaug G, Skalabrin E, et al. Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study. Ann Neurol. 2006; 60: 508-17.
    • (2006) Ann Neurol , vol.60 , pp. 508-517
    • Albers, G.W.1    Thijs, V.N.2    Wechsler, L.3    Kemp, S.4    Schlaug, G.5    Skalabrin, E.6
  • 2
    • 19944426190 scopus 로고    scopus 로고
    • The Desmoteplase in Acute Ischemic Stroke Trial (DIAS): A phase II MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase
    • Hacke W, Albers G, Al-Rawi Y, Bogousslavsky J, Davalos A, Eliasziw M, et al. The Desmoteplase in Acute Ischemic Stroke Trial (DIAS): a phase II MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase. Stroke. 2005; 36: 66-73.
    • (2005) Stroke , vol.36 , pp. 66-73
    • Hacke, W.1    Albers, G.2    Al-Rawi, Y.3    Bogousslavsky, J.4    Davalos, A.5    Eliasziw, M.6
  • 3
    • 33646705400 scopus 로고    scopus 로고
    • Dose Escalation of Desmoteplase for Acute Ischemic Stroke (DEDAS): Evidence of safety and efficacy 3 to 9 hours after stroke onset
    • Furlan AJ, Eyding D, Albers GW, Al-Rawi Y, Lees K, et al. Dose Escalation of Desmoteplase for Acute Ischemic Stroke (DEDAS): evidence of safety and efficacy 3 to 9 hours after stroke onset. Stroke. 2006; 37: 1227-31.
    • (2006) Stroke , vol.37 , pp. 1227-1231
    • Furlan, A.J.1    Eyding, D.2    Albers, G.W.3    Al-Rawi, Y.4    Lees, K.5
  • 4
    • 60549106702 scopus 로고    scopus 로고
    • Use of MRI to estimate the therapeutic window in acute stroke: Is perfusion-weighted imaging/diffusion-weighted imaging mismatch an EPITHET for salvageable ischemic brain tissue?
    • Toth G, Albers GW. Use of MRI to estimate the therapeutic window in acute stroke: is perfusion-weighted imaging/diffusion-weighted imaging mismatch an EPITHET for salvageable ischemic brain tissue? Stroke. 2009; 40: 333-5.
    • (2009) Stroke , vol.40 , pp. 333-335
    • Toth, G.1    Albers, G.W.2
  • 5
    • 0346881348 scopus 로고    scopus 로고
    • Pixel-by-pixel spatiotemporal progression of focal ischemia derived using quantitative perfusion and diffusion imaging
    • Shen Q, Meng X, Fisher M, Sotak CH, Duong TQ. Pixel-by-pixel spatiotemporal progression of focal ischemia derived using quantitative perfusion and diffusion imaging. J Cereb Blood Flow Metab. 2003; 23: 1479-88.
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 1479-1488
    • Shen, Q.1    Meng, X.2    Fisher, M.3    Sotak, C.H.4    Duong, T.Q.5
  • 6
    • 34247880466 scopus 로고    scopus 로고
    • Characterizing tissue fate after transient cerebral ischemia of varying duration using quantitative diffusion and perfusion imaging
    • Bardutzky J, Shen Q, Henninger N, Schwab S, Duong TQ, Fisher M. Characterizing tissue fate after transient cerebral ischemia of varying duration using quantitative diffusion and perfusion imaging. Stroke. 2007; 38: 1336-44.
    • (2007) Stroke , vol.38 , pp. 1336-1344
    • Bardutzky, J.1    Shen, Q.2    Henninger, N.3    Schwab, S.4    Duong, T.Q.5    Fisher, M.6
  • 7
    • 1542376867 scopus 로고    scopus 로고
    • Effects of reperfusion on ADC and CBF pixel-by-pixel dynamics in stroke: Characterizing tissue fates using quantitative diffusion and perfusion imaging
    • Shen Q, Fisher M, Sotak CH, Duong TQ. Effects of reperfusion on ADC and CBF pixel-by-pixel dynamics in stroke: characterizing tissue fates using quantitative diffusion and perfusion imaging. J Cereb Blood Flow Metab. 2004; 24: 280-90.
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 280-290
    • Shen, Q.1    Fisher, M.2    Sotak, C.H.3    Duong, T.Q.4
  • 8
    • 3843091836 scopus 로고    scopus 로고
    • Dynamic tracking of acute ischemic tissue fates using improved unsupervised ISODATA analysis of high-resolution quantitative perfusion and diffusion data
    • Shen Q, Ren H, Fisher M, Bouley J, Duong TQ. Dynamic tracking of acute ischemic tissue fates using improved unsupervised ISODATA analysis of high-resolution quantitative perfusion and diffusion data. J Cereb Blood Flow Metab. 2004; 24: 887-97.
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 887-897
    • Shen, Q.1    Ren, H.2    Fisher, M.3    Bouley, J.4    Duong, T.Q.5
  • 9
    • 25144441310 scopus 로고    scopus 로고
    • Statistical prediction of tissue fate in acute ischemic brain injury
    • Shen Q, Ren H, Fisher M, Duong TQ. Statistical prediction of tissue fate in acute ischemic brain injury. J Cereb Blood Flow Metab. 2005; 25: 1336-45.
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 1336-1345
    • Shen, Q.1    Ren, H.2    Fisher, M.3    Duong, T.Q.4
  • 10
    • 0035074072 scopus 로고    scopus 로고
    • A model for multiparametric MRI tissue characterization in experimental cerebral ischemia with histological validation in rat. Part 1
    • Jacobs MA, Zhang ZG, Knight RA, Soltanian-Zadeh H, Goussev AV, Peck DJ, et al. A model for multiparametric MRI tissue characterization in experimental cerebral ischemia with histological validation in rat. Part 1. Stroke. 2001; 32: 943-49.
    • (2001) Stroke , vol.32 , pp. 943-949
    • Jacobs, M.A.1    Zhang, Z.G.2    Knight, R.A.3    Soltanian-Zadeh, H.4    Goussev, A.V.5    Peck, D.J.6
  • 11
    • 0035071073 scopus 로고    scopus 로고
    • Multiparametric MRI tissue characterization in clinical stroke with correlation to clinical outcome: Part 2
    • Jacobs MA, Mitsias P, Soltaniaan-Zadeh H, Santhakumar S, Ghanei A, Hammound R, et al. Multiparametric MRI tissue characterization in clinical stroke with correlation to clinical outcome: part 2. Stroke. 2001; 32: 950-57.
    • (2001) Stroke , vol.32 , pp. 950-957
    • Jacobs, M.A.1    Mitsias, P.2    Soltaniaan-Zadeh, H.3    Santhakumar, S.4    Ghanei, A.5    Hammound, R.6
  • 12
    • 0036903349 scopus 로고    scopus 로고
    • Multiparametric MRI ISODATA ischemic lesion analysis correlation with the clinical neurological deficit and single parameter MRI techniques
    • Mitsias PD, Jacobs MA, Hammound R, Pasnoor M, Santhakumar S, Papamitsakis NIH, et al. Multiparametric MRI ISODATA ischemic lesion analysis correlation with the clinical neurological deficit and single parameter MRI techniques. Stroke. 2002; 33: 2839-844.
    • (2002) Stroke , vol.33 , pp. 2839-2844
    • Mitsias, P.D.1    Jacobs, M.A.2    Hammound, R.3    Pasnoor, M.4    Santhakumar, S.5    Papamitsakis, N.I.H.6
  • 13
    • 33744600902 scopus 로고    scopus 로고
    • National Institute of Neurological Disorders
    • National Institute of Neurological Disorders. National Institutes of Health: Acute stroke treatment. http://www. ninds. nih. gov/find_people/groups/stroke_prg/09_2006_stroke_prg_report. htm#ACUTE.
    • National Institutes of Health: Acute stroke treatment
  • 14
    • 0029844856 scopus 로고    scopus 로고
    • Long-lasting neuroprotective effect of postischemic hypothermia and treatment with an anti-inflammatory/antipyretic drug. Evidence for chronic encephalopathic processes following ischemia
    • Coimbra C, Drake M, Boris-Möller F, Wieloch T. Long-lasting neuroprotective effect of postischemic hypothermia and treatment with an anti-inflammatory/antipyretic drug. Evidence for chronic encephalopathic processes following ischemia. Stroke. 1996; 27: 1578-85.
    • (1996) Stroke , vol.27 , pp. 1578-1585
    • Coimbra, C.1    Drake, M.2    Boris-Möller, F.3    Wieloch, T.4
  • 15
    • 0027231086 scopus 로고
    • Intraischemic but not postischemic hypothermia protects chronically following global forebrain ischemia in rats
    • Dietrich WD, Busto R, Alonso O, Globus MY-T, Ginsburg MD. Intraischemic but not postischemic hypothermia protects chronically following global forebrain ischemia in rats. J Cereb Blood Flow Metab. 1993; 13: 541-49.
    • (1993) J Cereb Blood Flow Metab , vol.13 , pp. 541-549
    • Dietrich, W.D.1    Busto, R.2    Alonso, O.3    Globus, M.Y.-T.4    Ginsburg, M.D.5
  • 16
    • 33846006516 scopus 로고    scopus 로고
    • Wide therapeutic time window for fasudil neuroprotection against ischemia-induced delayed neuronal death in gerbils
    • Satoh S, Toshima Y, Ikegaki I, Iwasaki M, Asano T. Wide therapeutic time window for fasudil neuroprotection against ischemia-induced delayed neuronal death in gerbils. Brain Res. 2007; 1128: 175-80.
    • (2007) Brain Res , vol.1128 , pp. 175-180
    • Satoh, S.1    Toshima, Y.2    Ikegaki, I.3    Iwasaki, M.4    Asano, T.5
  • 18
    • 33646170949 scopus 로고    scopus 로고
    • The combination of isoflurane and caspase 8 inhibition results in sustained neuroprotection in rats subject to focal cerebral ischemia
    • Inoue S, Davis DP, Drummond J, Cole DJ, Patel PM. The combination of isoflurane and caspase 8 inhibition results in sustained neuroprotection in rats subject to focal cerebral ischemia. Anesth Analg. 2006; 102: 1548-55.
    • (2006) Anesth Analg , vol.102 , pp. 1548-1555
    • Inoue, S.1    Davis, D.P.2    Drummond, J.3    Cole, D.J.4    Patel, P.M.5
  • 19
    • 0242694042 scopus 로고    scopus 로고
    • Beyond mismatch: Evolving paradigms in imaging the ischemic penumbra with multimodality magnetic resonance imaging
    • Kidwell CS, Alger JS, Saver JL. Beyond mismatch: evolving paradigms in imaging the ischemic penumbra with multimodality magnetic resonance imaging. Stroke. 2003; 34: 2729-35.
    • (2003) Stroke , vol.34 , pp. 2729-2735
    • Kidwell, C.S.1    Alger, J.S.2    Saver, J.L.3
  • 20
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischemic stroke: An integrated view
    • Dirnagl U, Iadecola C, Moskowitz M. Pathobiology of ischemic stroke: an integrated view. Trends Neurosci. 1999; 22: 391-7.
    • (1999) Trends Neurosci , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.3
  • 21
    • 70349653317 scopus 로고    scopus 로고
    • Geography, structure and evolution of diffusion and perfusion lesions in diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE)
    • Olivot J, Mlynash M, Thijs VN, Purushotham A, Kemp S, Lansberg MG. Geography, structure and evolution of diffusion and perfusion lesions in diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE). Stroke. 2009; 40: 3245-2351.
    • (2009) Stroke , vol.40 , pp. 3245-2351
    • Olivot, J.1    Mlynash, M.2    Thijs, V.N.3    Purushotham, A.4    Kemp, S.5    Lansberg, M.G.6
  • 22
    • 8344252685 scopus 로고    scopus 로고
    • Does the acute diffusion-weighted imaging lesion represent penumbra as well as core? A combined quantitative PET/MRI voxel-based study
    • Guadagno JV, Warburton EA, Aigbirhio FI, Smielewski P, Fryer TD, Harding S, et al. Does the acute diffusion-weighted imaging lesion represent penumbra as well as core? A combined quantitative PET/MRI voxel-based study. J Cereb Blood Flow Metab. 2004; 24: 1249-54.
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 1249-1254
    • Guadagno, J.V.1    Warburton, E.A.2    Aigbirhio, F.I.3    Smielewski, P.4    Fryer, T.D.5    Harding, S.6
  • 23
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniotomy in the rat
    • Longa EZ, Weinstein PR, Carlson S, Cummins R. Reversible middle cerebral artery occlusion without craniotomy in the rat. Stroke. 1989; 20: 84-91.
    • (1989) Stroke , vol.20 , pp. 84-91
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3    Cummins, R.4
  • 25
  • 26
    • 0032850851 scopus 로고    scopus 로고
    • Early perfusion after controlled cortical impact in rats: Quantification by arterial spin-labeled MRI and the influence of spin-lattice relaxation time heterogeneity
    • Hendrich KS, Kochanek PM, Williams DS, Schiding JK, Marion DW, Ho C. Early perfusion after controlled cortical impact in rats: quantification by arterial spin-labeled MRI and the influence of spin-lattice relaxation time heterogeneity. Magn Reson Med. 1999; 42: 673-81.
    • (1999) Magn Reson Med , vol.42 , pp. 673-681
    • Hendrich, K.S.1    Kochanek, P.M.2    Williams, D.S.3    Schiding, J.K.4    Marion, D.W.5    Ho, C.6
  • 28
    • 0028961859 scopus 로고
    • NMR measurement of perfusion using arterial spin labeling without saturation of macromolecular spins
    • Zhang W, Williams SAC, DS KAP. NMR measurement of perfusion using arterial spin labeling without saturation of macromolecular spins. Magn Reson Med. 1995; 33: 370-6.
    • (1995) Magn Reson Med , vol.33 , pp. 370-376
    • Zhang, W.1    Williams, S.A.C.2    Ds, K.A.P.3
  • 29
    • 0021991039 scopus 로고
    • What is the correct value for the brain-blood partition coefficient for water?
    • Herscovitch P, Raichle ME. What is the correct value for the brain-blood partition coefficient for water? J Cereb Blood Flow Metab. 1985; 5: 65-9.
    • (1985) J Cereb Blood Flow Metab , vol.5 , pp. 65-69
    • Herscovitch, P.1    Raichle, M.E.2
  • 30
    • 0027474297 scopus 로고
    • Measurement of rat brain perfusion by NMR using spin labeling of arterial water: In vivo determination of the degree of spin labeling
    • Zhang W, Williams DS, Koretsky AP. Measurement of rat brain perfusion by NMR using spin labeling of arterial water: in vivo determination of the degree of spin labeling. Magn Reson Med. 1993; 29: 416-21.
    • (1993) Magn Reson Med , vol.29 , pp. 416-421
    • Zhang, W.1    Williams, D.S.2    Koretsky, A.P.3
  • 31
    • 33646376290 scopus 로고
    • Spin diffusion measurements: Spin echoes in the presence of a time-dependent field gradient
    • Stejskal EO, Tanner JE. Spin diffusion measurements: spin echoes in the presence of a time-dependent field gradient. J Chem Phys. 1965; 42: 288-92.
    • (1965) J Chem Phys , vol.42 , pp. 288-292
    • Stejskal, E.O.1    Tanner, J.E.2
  • 32
    • 0034961911 scopus 로고    scopus 로고
    • Cerebral perfusion during anesthesia with fentanyl, isoflurane, or pentobarbital in normal rats studied by arterial spin-labeled MRI
    • Hendrich KS, Kochanek PM, Melick JA, Schiding JK, Statler KD, Williams DS, et al. Cerebral perfusion during anesthesia with fentanyl, isoflurane, or pentobarbital in normal rats studied by arterial spin-labeled MRI. Magn Reson Med. 2001; 46: 202-6.
    • (2001) Magn Reson Med , vol.46 , pp. 202-206
    • Hendrich, K.S.1    Kochanek, P.M.2    Melick, J.A.3    Schiding, J.K.4    Statler, K.D.5    Williams, D.S.6
  • 33
    • 0028811177 scopus 로고
    • Evolution of regional changes in apparent diffusion coefficient during focal ischemia of rat brain: The relationship of quantitative diffusion NMR Imaging to reduction in cerebral blood flow and metabolic disturbances
    • Hoehn-Berlage M, Norris DG, Kohno K, Mies G, Leibfritz D, Hossmann K-A. Evolution of regional changes in apparent diffusion coefficient during focal ischemia of rat brain: the relationship of quantitative diffusion NMR Imaging to reduction in cerebral blood flow and metabolic disturbances. J Cereb Blood Flow Metab. 1995; 15: 1002-11.
    • (1995) J Cereb Blood Flow Metab , vol.15 , pp. 1002-1011
    • Hoehn-Berlage, M.1    Norris, D.G.2    Kohno, K.3    Mies, G.4    Leibfritz, D.5    Hossmann, K.-A.6
  • 34
    • 0028869998 scopus 로고
    • Relationship between diffusion-weighted MR images, cerebral blood flow, and energy state in experimental brain infarction
    • Kohno K, Hoehn-Berlage M, Mies G, Back T, Hossmann K-A. Relationship between diffusion-weighted MR images, cerebral blood flow, and energy state in experimental brain infarction. Mag Res Imag. 1995; 13: 73-80.
    • (1995) Mag Res Imag , vol.13 , pp. 73-80
    • Kohno, K.1    Hoehn-Berlage, M.2    Mies, G.3    Back, T.4    Hossmann, K.-A.5
  • 35
    • 0027982679 scopus 로고
    • Viability thresholds and the penumbra of focal ischemia
    • Hossmann K-A. Viability thresholds and the penumbra of focal ischemia. Ann Neurol. 1994; 36: 557-65.
    • (1994) Ann Neurol , vol.36 , pp. 557-565
    • Hossmann, K.-A.1
  • 36
    • 0028894752 scopus 로고
    • Multislice diffusion mapping for 3-D evolution of cerebral ischemia in a rat stroke model
    • Reith W, Hasegawa Y, Latour LL, Dardzinski BJ, Sotak CH, Fisher M. Multislice diffusion mapping for 3-D evolution of cerebral ischemia in a rat stroke model. Neurology. 1995; 45: 172-7.
    • (1995) Neurology , vol.45 , pp. 172-177
    • Reith, W.1    Hasegawa, Y.2    Latour, L.L.3    Dardzinski, B.J.4    Sotak, C.H.5    Fisher, M.6
  • 38
    • 0025360658 scopus 로고
    • A reversible component of cerebral injury as identified by the histochemical stain 2,3,5-triphenyltetrazolium chloride (TTC)
    • Cole DJ, Drummond JC, Ghazal EA, Shapiro HM. A reversible component of cerebral injury as identified by the histochemical stain 2, 3, 5-triphenyltetrazolium chloride (TTC). Acta Neuropathol. 1990; 80(2): 152-5.
    • (1990) Acta Neuropathol , vol.80 , Issue.2 , pp. 152-155
    • Cole, D.J.1    Drummond, J.C.2    Ghazal, E.A.3    Shapiro, H.M.4
  • 39
    • 0141754078 scopus 로고    scopus 로고
    • The cortical ischemic core and not the consistently present penumbra is a determinant of clinical outcome in acute middle cerebral artery occlusion
    • Jovin TG, Yonas H, Gebel JM, Kanal E, Chang YF, Grahovac SZ, et al. The cortical ischemic core and not the consistently present penumbra is a determinant of clinical outcome in acute middle cerebral artery occlusion. Stroke. 2003; 34: 2426-33.
    • (2003) Stroke , vol.34 , pp. 2426-2433
    • Jovin, T.G.1    Yonas, H.2    Gebel, J.M.3    Kanal, E.4    Chang, Y.F.5    Grahovac, S.Z.6
  • 40
    • 2942538277 scopus 로고    scopus 로고
    • Hypoxic tissue in ischaemic stroke: Persistence and clinical consequences of spontaneous survival
    • Markus R, Reutens DC, Kazui S, Read S, Wright P, Pearce DC, et al. Hypoxic tissue in ischaemic stroke: persistence and clinical consequences of spontaneous survival. Brain. 2004; 127: 1427-36.
    • (2004) Brain , vol.127 , pp. 1427-1436
    • Markus, R.1    Reutens, D.C.2    Kazui, S.3    Read, S.4    Wright, P.5    Pearce, D.C.6
  • 41
    • 0030826280 scopus 로고    scopus 로고
    • Progressive impairment of brain oxidative metabolism reversed by reperfusion following middle cerebral artery occlusion in anesthetized baboons
    • Touzani O, Young AR, Derlon JR, Baron JC, MacKenzie ET. Progressive impairment of brain oxidative metabolism reversed by reperfusion following middle cerebral artery occlusion in anesthetized baboons. Brain Res. 1997; 767: 17-25.
    • (1997) Brain Res , vol.767 , pp. 17-25
    • Touzani, O.1    Young, A.R.2    Derlon, J.R.3    Baron, J.C.4    Mackenzie, E.T.5
  • 43
    • 77954956242 scopus 로고    scopus 로고
    • Lesley M, Foley T, Hitchens K, Barbe B, Horner J, Ho C, Nemoto E. Brain tissue ischemic transitions during permanent middle cerebral artery occlusion (pMCAO) in rats. In: ISMRM 16th Conference, Toronto, Canada, 5-9 May, 2008 [Abstract #3297].
  • 44
    • 0030669916 scopus 로고    scopus 로고
    • Incomplete infarct and delayed neuronal death after transient middle cerebral artery occlusion in animals
    • Garcia JH, Liu K-F, Ye Z-R, Gutierrez JA. Incomplete infarct and delayed neuronal death after transient middle cerebral artery occlusion in animals. Stroke. 1997; 28: 2303-10.
    • (1997) Stroke , vol.28 , pp. 2303-2310
    • Garcia, J.H.1    Liu, K.-F.2    Ye, Z.-R.3    Gutierrez, J.A.4


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