N-(2-hydroxy phenyl) acetamide inhibits inflammation-related cytokines and ROS in adjuvant-induced arthritic (AIA) rats

International Immunopharmacology

Volumn 10, Issue 8, 2010, Pages 900-905

  Jawed, Huma ^a   Shah, Syed Uzair Ali ^a   Jamall, Siddiqua ^a   Simjee, Shabana Usman ^a  

^a UNIVERSITY OF KARACHI   (Pakistan)

Author keywords

Adjuvant induced arthritis; Anti arthritic; Anti inflammatory; N (2 hydroxy phenyl) acetamide; Oxidative stress markers; Pro inflammatory cytokines

Indexed keywords

ACETAMIDE DERIVATIVE; ANTIRHEUMATIC AGENT; GLUTATHIONE SYNTHASE; INTERLEUKIN 1BETA; N (2 HYDROXY PHENYL) ACETAMIDE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADJUVANT ARTHRITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FEMALE; NONHUMAN; OXIDATIVE STRESS; PAW EDEMA; PRIORITY JOURNAL; PROTEIN DETERMINATION; RAT; WEIGHT REDUCTION;

ACETANILIDES; ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, EXPERIMENTAL; BIOLOGICAL MARKERS; EDEMA; FEMALE; INFLAMMATION; INTERLEUKIN-1BETA; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; TUMOR NECROSIS FACTOR-ALPHA; WEIGHT LOSS;

EID: 77954952064     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2010.04.028     Document Type: Article

References (70)

1. LaPlante M.P. Data on disability from the National Health Interview Survey, 1983-85 1988, Dept. of Education (US), National Institute on Disability and Rehabilitation Research, Washington.
2. Verbrugge L.M. Women, men, and osteoarthritis. Arthritis Care Res 1995, 8:212-220.
3. Centers for Disease Control and Prevention Prevalence of disabilities and associated health conditions among adults: United States, 1999 [published erratum appears in MMWR Morb Mortal Wkly Rep 2001; 50:149]. MMWR Morb Mortal Wkly Rep 2001, 50:120-125.
4. Brodin N., Eurenius E., Jensen I., Nisell R., Opava C.H. Coaching patients with early rheumatoid arthritis to healthy physical activity: a multicenter, randomized, controlled study. Arthritis Rheum 2008, 59(3):325-331.
5. Feldmann M., Brennan F.M., Maini R.N. Rheumatoid arthritis. Cell 1996, 85:307-331.
6. Firestein G.S. Rheumatoid arthritis: etiology and pathogenesis of rheumatoid arthritis. Kelley's textbook of rheumatology 2005, 996-1045. W.B. Saunders Co., Philadelphia, PA. S. Ruddy, E.D. Harris, C.B. Sledge, W.N. Kelley (Eds.).
7. Andersson A.K., Li C., Brennan F.M. Recent developments in the immunobiology of rheumatoid arthritis. Arthritis Res Ther 2008, 10:204-212.
8. Nielen M.M., van Schaardenburg D., Reesink H.W., Twisk J.W., van de Stadt R.J., van der Horst-Bruinsma I.E., et al. Simultaneous development of acute phase response and autoantibodies in preclinical rheumatoid arthritis. Ann Rheum Dis 2006, 65:535-537.
9. Weyand C.M., Goronzy J.J., Takemura S., Kurtin P.J. Cell-cell interactions in synovitis. Interactions between T cells and B cells in rheumatoid arthritis. Arthritis Res 2000, 2:457-463.
10. Kaplan C., Valdez J.C., Chandrasekaran R., Eibel H., Mikecz K., et al. Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis. Arthritis Res 2002, 4:545-558.
11. Maini R.N., Taylor P.C. Anti-cytokines therapy for rheumatoid arthritis. Annu Rev Med 2000, 51:207-229.
12. Blake D.R., Merry P., Unsworth J., Kidd B.L., Outhwaite J.M., Ballard R., et al. Hypoxic-reperfusion injury in the inflamed human joint. Lancet 1989, (i):289-293.
13. Freeman B.A., Crapo J.D. Biology of disease, free radicals and tissue injury. Lab Invest 1982, 47(5):412-426.
14. Valko M., Leibfritz D., Moncol J., Cronin M.T., Mazur M., Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 2007, 39(1):44-84.
15. Cadenas E. Basic mechanisms of antioxidant activity. Biofactors 1997, 6:391-397.
16. Heliovaara M., Knekt P., Aho K., Aaran R.K., Alfthan G., Aromaa A. Serum antioxidants and risk of rheumatoid arthritis. Ann Rheum Dis 1994, 53:51-53.
17. Gambhir J.K., Lali P., Jain A.K. Correlation between blood antioxidant levels and lipid peroxidation in rheumatoid arthritis. Clin Biochem 1997, 30:351-355.
18. Sakurai H., Kohsaka H., Liu M., Higashiyama H., Hirata Y., Kanno K., et al. Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides. J Clin Invest 1995, 96:2357-2363.
19. Wallace J.L. Nitric oxide as a regulator of inflammatory processes. Mem Inst Oswaldo Cruz 2005, 100:5-9.
20. Kizilntuc A., Cogalgil S., Cerrahoglu L. Carnitine and antioxidants levels in patients with rheumatoid arthritis. Scand J Rheumatol 1998, 27:441-445.
21. Hassan M.Q., Hadi R.A., Al-Rawi Z.S., Padron V.A., Stohs S.J. The glutathione defense system in the pathogenesis of rheumatoid arthritis. J Appl Toxicol 2001, 21:69-73.
22. Masella R., Di Benedetto R., Varì R., Filesi C., Giovannini C. Novel mechanisms of natural antioxidant compounds in biological systems. Involvement of glutathione and glutathione-related enzymes. J Nutr Biochem 2005, 16(10):577-586.
23. Kamanli A., Naziroglu M., Aydilek N., Hacievliyagil C. Plasma lipid peroxidation and antioxidant levels in patients with rheumatoid arthritis. Cell Biochem Funct 2004, 22(1):53-57.
24. Los M., Dröge W., Stricker K., Baeuerle P.A., Schulze-Osthoff K. Hydrogen peroxide as a potent activator of T lymphocyte functions. Eur J Immunol 1995, 25:159-165.
25. Tinker A.C., Wallace A.V. Selective inhibitors of inducible nitric oxide synthase: potential agents for the treatment of inflammatory diseases?. Curr Top Med Chem 2006, 6:77-92.
26. Ali M.H., Schlidt S.A., Chandel N.S., Hynes K.L., Schumacker P.T., Gewertz B.L. Endothelial permeability and IL-6 production during hypoxia: role of ROS in signal transduction. Am J Physiol 1999, 277(5):1057-1065.
27. 2 in rat heart endothelial cells. Free Radic Biol Med 1998, 25:891-897.
28. Simon A.R., Rai U., Fanburg B.L., Cochran B.H. Activation of the JAK-STAT pathway by reactive oxygen species. Am J Physiol 1998, 275(6 Pt 1):C1640-C1652.
29. 2 for platelet-derived growth factor signal transduction. Science 1995, 270:296-299.
30. Feldmann M., Brennan F.M., Maini R.N. Role of cytokines in rheumatoid arthritis. Annu Rev Immunol 1996, 14:397-440.
31. Severn P.S., Fraser S.G. Bilateral cataracts and glaucoma induced by long-term use of oral prednisolone bought over the internet. Lancet 2006, 368:618.
32. Biskupiak J.E., Brixner D.I., Howard K.B., Oderda G.M. Gastrointestinal complications of over-the-counter nonsteroidal antiinflammatory drugs. J Pain Palliat Care Pharmacother 2006, 20:7-14.
33. Hinz B., Brune K. Pain and osteoarthritis: new drugs and mechanisms. Curr Opin Rheumatol 2004, 16:628-633.
34. Schuna A.A., Megeff C. New drugs for the treatment of rheumatoid arthritis. Am J Health Syst Pharm 2000, 57:225-234.
35. Meyer-Kirchrath J., Schrör K. Cyclooxygenase-2 inhibition and side-effects of non-steroidal anti-inflammatory drugs in the gastrointestinal tract. Curr Med Chem 2000, 7:1121-1129.
36. Lester R.S., Knowles S.R., Shear N.H. The risks of systemic corticosteroid use. Dermatol Clin 1998, 16:277-287.
37. Lanza F.L. Endoscopic studies of gastric and duodenal injury after the use of ibuprofen, aspirin, and other nonsteroidal anti-inflammatory agents. Am J Med 1984, 77:19-24.
38. Santana-Sabagun E, Weisman MH. Nonsteroidal anti-inflammatory drugs. In: Ruddy S, Harris JED, Sledge CB, Budd RC, Sergent JS, editors. W.B. Kelly's textbook of rheumatology, Vol. 1: Edited by Saunders Company; 2001, p. 799-822.
39. Newman N.M., Ling R.S.M. Acetabular bone destruction related to non-steroidal anti-inflammatory drugs. Lancet 1985, 2:11-14.
40. Anastassiades T., Chopra R., Law C., Wong E. In vitro suppression of transforming growth factor-b induced stimulation of glycosaminoglycan synthesis by acetylsalicylic acid and its reversal by misoprostol. J Rheumatol 1998, 25:1962-1967.
41. Potter W.Z., Davis D.C., Mitchell J.R., Jollow D.J., Gillette J.R., Brodie B.B. Acetaminophen-induced hepatic necrosis. III. Cytochrome P-450-mediated covalent binding in vitro. J Pharmacol Exp Ther 1973, 187(1):203-210.
42. Mohandas J., Duggin G.G., Horvath J.S., Tiller D.J. Metabolic oxidation of acetaminophen (paracetamol) mediated by cytochrome P-450 mixed-function oxidase and prostaglandin endoperoxide synthetase in rabbit kidney. Toxicol Appl Pharmacol 1981, 61(2):252-259.
43. Patten C.J., Thomas P.E., Guy R.L., Lee M., Gonzalez F.J., Guengerich P., et al. Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics. Chem Res Toxicol 1993, 6(4):511-518.
44. Momin D.-e.-S., Khurshid S., Jawed H., Aslam K., Saeed S.A., Simjee S.U. Modulatory role of 2-acetamidophenolon the expression of CD44 cell surface markers in the brain of adjuvant induced arthritic model (AIA) of rats. Inflamm. Res. 2008, 57 (Suppl 2):S98-S99.
45. Saeed SA, Saeed SO. 2005; UK Patent No. 2405 092B. http://webdb2.patent.gov.uk/p-find-publication-getPDF.pdf?PatentNo=GB2405092&DocType=B&JournalNumber=6203.
46. Zimmerman M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 1983, 16:109-110.
47. Bakharevski O., Stein-Oakley A.N., Thomson N.M., Ryan P.F.J. Collagen-induced arthritis in rats: contrasting effect of subcutaneous versus intradermal inoculation of type II collagen. J Rheumatol 1998, 25:1945-1952.
48. Capetola R.J., Shriver D.A., Rosenthale M.E. Suprofen, a new peripheral analgesic. J Pharmacol Exp Ther 1980, 214:16-23.
49. Goronzy J.J., Weyand C.M. Thymic function and peripheral T-cell homeostasis in rheumatoid arthritis. Trends Immunol 2001, 22:251-255.
50. Kohem C.L., Brezinschek R.I., Wisbey H., Tortorella C., Lipsky P.E., Oppenheimer-Marks N. Enrichment of differentiated CD45RBdim, CD27 memory T cells in the peripheral blood, synovial fluid, and synovial tissue of patients with rheumatoid arthritis. Arthritis Rheum 1996, 39:844-854.
51. Falgarone G., Semerano L., Rullé S., Boissier M.C. Targeting lymphocyte activation to treat rheumatoid arthritis. Joint Bone Spine 2009, 76(4):327-332.
52. Abreu J.R., Grabiec A.M., Krausz S., Spijker R., Burakowski T., Maslinski W., et al. The presumed hyporesponsive behavior of rheumatoid arthritis T lymphocytes can be attributed to spontaneous ex vivo apoptosis rather than defects in T cell receptor signaling. J Immunol 2009, 183:621-630.
53. Vandooren B., Noordenbos T., Ambarus C., Krausz S., Cantaert T., Yeremenko N., et al. Absence of a classically activated macrophage cytokine signature in peripheral spondylarthritis, including psoriatic arthritis. Arthritis Rheum 2009, 60(4):966-975.
54. Panayi G.S., Lanchbury J.S., Kingsley G.H. The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis. Arthritis Rheum 1992, 35:729-735.
55. Szekanecz Z., Koch A.E., Kunkel S.L., Strieter R.M. Cytokines in rheumatoid arthritis: potential targets for pharmacological intervention. Drugs Aging 1998, 12:377-390.
56. Gravallese E.M., Goldring S.R. Cellular mechanism and the role of cytokines in bone erosions in rheumatoid arthritis. Arthritis Rheum 2000, 43:2143-2151.
57. Fan A.Y., Lao L., Zhang R.X., Zhou A.N., Wang L.B., Moudgil K.D., et al. Effects of an acetone extract of Boswellia carterii Birdw. (Burseraceae) gum resin on adjuvant-induced arthritis in lewis rats. J Ethnopharmacol 2005, 101(1-3):104-109.
58. Cai X., Zhou H., Wong Y.F., Xie Y., Liu Z.Q., Jiang Z.H., et al. Suppression of the onset and progression of collagen-induced arthritis in rats by QFGJS, a preparation from an anti-arthritic Chinese herbal formula. J Ethnopharmacol 2007, 110(1):39-48.
59. Wong Y.F., Zhou H., Wang J.R., Xie Y., Xu H.X., Liu L. Anti-inflammatory and analgesic effects and molecular mechanisms of JCICM-6, a purified extract derived from an anti-arthritic Chinese herbal formula. Phytomedicine 2008, 15(6-7):416-426.
60. Bauerova K., Bezek A. Role of reactive oxygen and nitrogen species in etiopathogenesis of rheumatoid arthritis. Gen Physiol Biophys 1999, 18:15-20.
61. Feldmann M., Brennan F.M., Foxwell B.M., Maini R.N. The role of TNF-alpha and IL-1 in rheumatoid arthritis. Curr Dir Autoimmun 2001, 3:188-199.
62. Knight J.A. Free radicals, antioxidants, and the immune system. Ann Clin Lab Sci 2000, 30:145-158.
63. Borel J.P., Monboisse J.C. Effect of oxygen free radicals on collagen in inflammation. Ann Biol Clin 1986, 44:260-265.
64. Monboisse J.C., Poulin G., Braquet P., Randoux A., Ferradini C., Borel J.P. Effect of oxy radicals on several types of collagen. Int J Tissue React 1984, 6:385-390.
65. Monboisse J.C., Gardes-Albert M., Randoux A., Borel J.P., Ferradini C. Collagen degradation by superoxide anion in pulse and gamma radiolysis. Biochim Biophys Acta 1988, 965:29-35.
66. Iyama S., Okamoto T., Sato T., Yamauchi N., Sato Y., Sasaki K., et al. Treatment of murine collagen-induced arthritis by ex vivo extracellular superoxide dismutase gene transfer. Arthritis Rheum 2001, 44(9):2160-2167.
67. Salvemini D., Ischiropoulos H., Cuzzocrea S. Roles of nitric oxide and superoxide in inflammation. Methods in molecular biology: inflammation protocols 2003, 291-303. Humana Press, Totowa, NJ. P.G. Winyard, D.A. Willoughby (Eds.).
68. Fahim A.T., Abd-El Fattah A.A., Agha A.M., Gad M.Z. Effect of pumpkin-seed oil on the level of free radical scavengers induced during adjuvant-arthritis in rats. Pharmacol Res 1995, 31(1):73-79.
69. McCord J.M. Free radicals and inflammation: protection of synovial fluid by superoxide dismutase. Science 1974, 185:529-531.
70. Greenwald R.A., Moy W.W. Effect of oxygen-derived free radicals on hyaluronic acid. Arthritis Rheum 1980, 23:455-463.