Carnitine and antioxidants levels in patients with rheumatoid arthritis

Scandinavian Journal of Rheumatology

Volumn 27, Issue 6, 1998, Pages 441-445

  Kiziltunç, Ahmet ^a   Çoǧalgil, Şirzat ^a   Cerrahoǧlu, Lale ^a  

^a ATATÜRK UNIVERSITY   (Turkey)

Author keywords

Antioxidant; Carnitine; Malondialdehyde; Rheumatoid arthritis

Indexed keywords

ANTIOXIDANT; CARNITINE; CATALASE; CERULOPLASMIN; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTATHIONE; MALONALDEHYDE;

ADULT; AMINO ACID BLOOD LEVEL; ARTICLE; CERULOPLASMIN BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ASSAY; ENZYME BLOOD LEVEL; FATTY ACID TRANSPORT; FEMALE; GLUTATHIONE METABOLISM; HUMAN; LIPID PEROXIDATION; MALE; MITOCHONDRIAL MEMBRANE; MUSCLE METABOLISM; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS;

EID: 0031728798     PISSN: 03009742     EISSN: None     Source Type: Journal    
DOI: 10.1080/030097498442271     Document Type: Article

References (38)

1. Horton AA, Fairhurst S. Lipid peroxidation and mechanisms of toxicity. Crit Rev Toxicol 1987;18:27-79.
2. Jurgens G, Hoff, Chisolm GM, Esterbauer H. Modification of human serum low density lipoprotein by oxidation-characterization and pathophysiological implications. Chem Phys Lipids 1987;45:315-36.
3. Hidalgo J, Gasull T, Garcia A, Blanguez A, Armario A, Role of glucocorticoids and catecholamines on hepatic thiobarbituric acid reactants in basal and stress conditions in the rat. Horm Metab Res 1991;23:104-9.
4. Halliwell B. Drug antioxidant effects. A basis for drug selection? Drugs 1991;42:569-605.
5. Bremer J. Carnitine metabolism and functions. Physiol Rev 1983;63:1421-80.
6. Pola P, Savi L, Grill M, Velardi F, Lago A. Carnitine in the therarpy of dyslipemic patients. Curr Ther Res 1980;27:208-16.
7. Lacour B, Chanard J, Haguet M, DiGiulio S, Chanard J, Ciancioni C, et al. Carnitine improves lipid anomalies in haemodialysis patients. Lancet 1980;12:763-4.
8. Seccombe DW, James L, Hahn P. Type V hyperlipoproteinemia with palmar erythema and eruptive xanthomas, effects of treatment with L-carnitine. III International Colloquium on Lipid Metabolism and its Pathology, Lisbon, Portugal, Sept. 1982:22-5.
9. Avogaro P, Bon GB, Cazzolato G, Rorai E. Acute effect of L-carnitine on FFA and β-Hydroxy-Butyrate in Man. Pharmacol Res Commun 1981;13:443-50.
10. Orzali A, Donzelli F, Enzi G, Rubaltelli FF. Effect of carnitine on lipid metabolism in the Newborn L-carnitine supplanentation during total parenteral Nutrition in the first 48 hours of life. Biol Neonate 1983;43:186-90.
11. Vacha GM, Giorcelli G, Silliprandi N, Corsi M. Favourable effects of L-carnitine treatmenet on hyper triglyceridemia in hemodialysis patients: Decisive role of low levels of high-density lipoprotein cholesterol. Am J Clin Nutr 1983;38:532-40.
12. Lerner A, Gruener N, Lancu TC. Serum carnitine concentrations in coeliac disease. Gut 1993;34:933-5.
13. Bieber LL, Emaus R, Valkner K, Farrell S. Possible functions of short chain and medium-chain carnitine acyltransferase. Fed Proc 1982;41:2858-63.
14. Chalmers RA, Stacey TE, Tracey BM, Sousa C, Roe CR, Millington DS, et al. L-carnitine insufficiency in disorders of organic acid metabolism response to L-carnitine by patients with methylmalonic aciduria and 3-hydroxy-3-methylglutaric aciduria. J Inherit Metab Dis 1984;7:109-10.
15. Pepper JR, Mumby S, Gutteridge JMC. Sequential oxidative damage and changes in iron-oxidising plasma antioxidant during cardiopulmonary bypass surgery. Free Radic Res 1994;21:377-85.
16. Gutteridge JMC, Quinlan GJ. Antioxidant protection against organic and inorganic oxygen radicalsby normal human plasma:the important primary role for iron-oxiding proteins. Biochim Biophys Acta 1993;1156:144-50.
17. Halliwell B, Gutteridge JMC. The antioxidants of human extracellular fluids. Arch Biochem Biophys 1990;28:1-8.
18. Lowry OH, Rosenburg MY, Farr AL, Randall RT. Protein measurement with the folin phenol reagent. J Biol Chim 1951;193:265-75.
19. Satoh K. Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method. Clin Chim Acta 1978;90:37-43.
20. Paynter DI. Changes in activity of the manganese superoxide dismutase enzyme in tissues of the rat with changes in dietary manganese. J Nutr 1986;110:437-47.
21. Misra HP, Fridovich I. Superoxide dismutase: Photochemical augmentation assay. Arch Biochem Biophys 1977;181:308-12.
22. Aebi H. Catalase in vitro. Methods Enzymol 1984;105:121-6.
23. Griffith OW. Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal Biochem 1980;106:207-12.
24. Harparkash K, Barry H. Nitrotyrosine in serum and synovial fluid from rheumatoid patients. FEBS Lett 1994;350:9-12.
25. Bhuiyan AKMJ, Jackson S, Turnbull DM, Aynsley-Green A, Leonard JV, Bartlett K. The measurement of carnitine and acyl-carnitines: application to the investigation of patients with suspected inherited disorders of mitochondrial fatty acid oxidation. Clin Chem Acta 1992;207:185-204.
26. Stanley CA, Hale DE, Coates PM, Hall CL, Corkey BE, Yang W, et al. Medium-chain acyl-CoA dehydrogenase deficiency in children with non-ketotic hypoglycemia and low carnitine levels. Pediatr Res 1983;17:877-84.
27. Halliwel B, Gutteridge JMC. Role of free radicals and catalytic metal ions in human disease:an overview. In: Packer L, Glazer AN, eds. Methods in enzymology:oxygen radicals in biological systems. B San Diego: Academic Press, 1990:1-83.
28. Halliwell B, Gutteridge JMC. Lipid peroxidation, oxygen radicals, cell damage, and antioxidant therapy. Lancet 1984;8391:1396-2007.
29. Lunec J, Halloran SP, Whithe AG, Dormandy TL. Free radical oxidation products in serum and synovial fluid in rheumatoid arthritis. J Rheumatol 1981;8:233-45.
30. Rister M, Bauermeister K, Gravert U, Gladtke E. Superoxide dismutase deficiency in rheumatoid arthritis. Lancet 1978;8073:1094.
31. Chance B, Sies H, Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol Rev 1979;59:527-605.
32. 2 better than do erythrocytes from non-smokers. Am Rev Respir Dis 1986;134:281-4.
33. Schraufstatter IU, Hinshaw DB, Hyslop PA, Spragg RG, Cochrane CG. Glutathione cycle activity and pyridine nucleotide levels in oxidant-induced injury of cells. J Clin Invest 1985;76:1131-9.
34. Stocks J, Gutteridge JMC, Sharp RJ, Dormandy TL. The inhibition of lipid autoxidation by human serum and its relation to serum proteins and alpha-tocopherol. Clin Sci (Colch) 1974;47:223-33.
35. Biemond P, Swaak AJG, Koster JF. Protective factors against oxygen free radicals and hydrogen peroxide in rheumatoid arthritis synovial fluid. Arthritis Rheum 1984;27:760-5.
36. Denko CW. Protective role of ceruloplasmin in inflammation. Agents Actions 1979:333-6.
37. Scudder PR, Timmi D, McMurray W, While AG, Zoob BC, Dormandy TL. Serum copper and related variables in rheumatoid arthritis. Ann Rheum Dis 1978;37:67-70.
38. Banford JC, Brown DH, Hazelton RA, McNeil CJ, Sturrock RD, Smit WE. Serum copper and crythrocyte superoxide dismutase in rheumatoid arthritis. Ann Rheum Dis 1982; 41:458-62.