Antispasmodic and antioxidant activities of fractions and bioactive constituent davidigenin isolated from Mascarenhasia arborescens

Journal of Ethnopharmacology

Volumn 130, Issue 2, 2010, Pages 320-328

  Desire, Odile ^a,b   Rivière, Céline ^c   Razafindrazaka, René ^b   Goossens, Laurence ^e   Moreau, Stéphane ^f   Guillon, Jean ^f   Uverg Ratsimamanga, Suzanne ^b   Andriamadio, Pascal ^a   Moore, Nicholas ^c   Randriantsoa, Adolphe ^b   Raharisololalao, Amélie ^d  

^a University of Antsiranana   (Madagascar)

^b INSTITUT MALGACHE DE RECHERCHES APPLIQUÉES   (Madagascar)

^c INSERM U657   (France)

^d UNIVERSITY OF ANTANANARIVO   (Madagascar)

^e Faculté des Sciences Pharmaceutiques et Biologiques Université de Lille   (France)

^f Laboratoire de Pharmacochimie   (France)

Author keywords

Antioxidant; Antispasmodic; Apocynaceae; Davidigenin; Madagascar; Mascarenhasia arborescens

Indexed keywords

ACETYLCHOLINE; ANTIOXIDANT; DAVIDIGENIN; HISTAMINE; MASCARENHASIA ARBORESCENS EXTRACT; METHANOL; PHENOL; PLANT EXTRACT; SPASMOLYTIC AGENT; UNCLASSIFIED DRUG; 2,2-DIPHENYL-1-PICRYLHYDRAZYL; BIPHENYL DERIVATIVE; CHALCONE; CHALCONE DERIVATIVE; CHOLINERGIC RECEPTOR BLOCKING AGENT; PHENOL DERIVATIVE; PICRIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ANTISPASMODIC ACTIVITY; APOCYNACEAE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; DUODENUM; EXPERIMENTAL GUINEA PIG; FEMALE; FRACTIONATION; GUINEA PIG; ILEUM; INTESTINE CONTRACTION; MALE; MASCARENHASIA ARBORESCENS; MUSCLE RELAXATION; NONHUMAN; RAT; ANALOGS AND DERIVATIVES; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; ISOLATION AND PURIFICATION; REVERSED PHASE LIQUID CHROMATOGRAPHY; ULTRAVIOLET SPECTROPHOTOMETRY; WISTAR RAT;

APOCYNACEAE; CAVIA; MASCARENHASIA ARBORESCENS; RATTUS;

ANIMALS; ANTIOXIDANTS; APOCYNACEAE; BIPHENYL COMPOUNDS; CHALCONE; CHALCONES; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; DOSE-RESPONSE RELATIONSHIP, DRUG; DUODENUM; FEMALE; GUINEA PIGS; ILEUM; IN VITRO TECHNIQUES; MALE; MOLECULAR STRUCTURE; MUSCLE RELAXATION; PARASYMPATHOLYTICS; PHENOLS; PICRATES; PLANT EXTRACTS; RATS; RATS, WISTAR; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 77954951544     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.05.017     Document Type: Article

References (44)

1. Aquino R., Morelli S., Rosaria Lauro M., Abdo S., Saija A., Tomaino A. Phenolic constituents and antioxidant activity of an extract of Anthurium versicolor leaves. Journal of Natural Products 2001, 64:1019-1023.
2. Asano T., Ishihara K., Morota T., Takeda S., Aburada M. Permeability of the flavonoids liquiritigenin and its glycosides in licorice roots and davidigenin, a hydrogenated metabolite of liquiritigenin, using human intestinal cell line Caco-2. Journal of Ethnopharmacology 2003, 89:285-289.
3. Berridge M.J, Irwin R.F. Inositol phosphates and cell signalling. Nature 1989, 341:197-204.
4. Berridge M.J. Cytoplasmic calcium oscillation: a two pool model. Cell Calcium 1991, 12:63-72.
5. Boisier P., Ramarokoto C.E., Ravoniarimbinina P., Rabarijoana L., Ravaoalimalala V.E. Geographic differences in hepatosplenic complications of Schistosomiasis mansoni and explanatory factors of morbidity. Tropical Medicine and International Health 2001, 6:699-706.
6. Buchy P. The human intestinal parasites in Mahajanga, west coast of Madagascar. Bulletin de la Société de Pathologie Exotique 2003, 96:41-45.
7. Capasso A., Pinto A., Mascolo N., Autore G., Capasso F. Reduction of agonist-induced contractions of guinea-pig isolated ileum by flavonoids. Phytotherapy Research 1991, 5:85-87.
8. Capasso A., Pinto A., Sorrentino R., Capasso F. Inhibitory effects of quercetin and other flavonoids on electrically-induced contractions of guinea pig isolated ileum. Journal of Ethnopharmacology 1991, 34:279-281.
9. Cassel-Beraud A.M., Morvan J., Rakotoarimanana D.R., Razanamparany M., Candito D., Ravaomanarivo A.M., Coulanges P. Infantile diarrheal diseases in Madagascar: bacterial, parasitologic and viral study. Archives de l'Institut Pasteur de Madagascar 1990, 57:223-254.
10. Cassel-Beraud A.M., Morvan J., Coulanges P. Evaluation of the prevalence of the main enteropathogenic agents in the West Imerina region: Manarintsoa. Archives de l'Institut Pasteur de Madagascar 1990, 57:255-264.
11. Chen G., Zhu L., Liu Y., Zhou Q., Chen H., Yang J. Isoliquiritigenin, a flavonoid from licorice, plays a dual role in regulating gastrointestinal motility in vitro and in vivo. Phytotherapy Research 2009, 23:498-506.
12. Di Carlo G., Autore G., Izzo A.A., Maiolino P., Mascolo N., Viola P., Diurno M.V., Capasso F. Inhibition of intestinal motility and secretion by flavonoids in mice and rats: structure-activity relationships. Journal of Pharmacy and Pharmacology 1993, 45:1054-1059.
13. Di Carlo G., Izzo A.A., Borrelli F., Pinto L., Perilli S., Capasso F. Role of nitric oxide in gastro-intestinal effects of quercetin. Phytotherapy Research 1996, 10:114-115.
14. Di Carlo G., Mascolo N., Izzo A.A., Capasso F. Flavonoids: old and new aspects of a class of natural therapeutic drugs. Life Sciences 1999, 65:337-353.
15. Emendörfer F., Bellato F., Noldin V.F., Niero R., Cechinelfilho V., Cardozo A.M. Evaluation of the relaxant action of some Brazilian medicinal plants in isolated guinea-pig ileum and rat duodenum. Journal of Pharmacological Sciences 2005, 8:63-68.
16. Ghayur M.N., Gilani A.H., Khan A., Amor E.C., Villasenor I.M., Choudhary M.I. Presence of calcium antagonist activity explains the use of Syzygium samarangense in diarrhoea. Phytotherapy Research 2006, 20:49-52.
17. Ghosh M.N. Fundamentals of Experimental Pharmacology 1984, Scientific Book Agency, Calcutta.
18. Guo J., Liu D., Nikolic D., Zhu D., Pezzuto J.M., Van Breemen R.B. In vitro metabolism of isoliquiritigenin by human liver microsomes. Drug Metabolism and Disposition 2008, 36:461-468.
19. Harborne J.B., Williams C.A. Advances in flavonoid research since 1992. Phytochemistry 2000, 55:481-504.
20. Hashimoto R., Hirata M., Ito Y. A role of inositol 1,4,5-triphosphate in the initiation of agonist-induced contractions of dog tracheal muscle. British Journal of Pharmacology 1985, 86:191-199.
21. Homma M., Oka K., Taniguchi C., Niitsuma T., Hayashi T. Systematic analysis of post-administrative Saiboku-To urine by liquid chromatography to determine pharmacokinetics of traditional Chinese medicine. Biochemical Chromatography 1997, 11:125-131.
22. Homma M., Minami M., Taniguchi C., Oka K., Morita S., Niitsuma T., Hayashi T. Inhibitory effects of lignans and flavonoids in Saiboku-To, a herbal medicine for bronchial asthma, on the release of leukotrienes from human polymorphonuclear leukocytes. Planta Medica 2000, 66:88-91.
23. Jensen R.S., Nielsen B.J., Norn V. Dihydrochalcones from Viburnum davidii and V. lantanoides. Phytochemistry 1977, 16:2036-3038.
24. Kamai J., Saitoh A., Asano T., Nakamura R., Ichiki H., Iiduka A., Kubo M. Pharmacokinetic and pharmacodynamic profiles of the antitussive principles of Glycyrrhizae radix (licorice), a main component of the Kampo preparation Bakumondo-to (Mai-men-dong-tang). European Journal of Pharmacology 2005, 507:163-168.
25. Karaki H., Weiss G. Mini-review: calcium release in smooth muscles. Life Science 1988, 42:111-122.
26. Li C., Homma M., Oka K. Characteristics of delayed excretion of flavonoids in human urine after administration of Shosaiko-to, an herbal medicine. Biological Pharmaceutical Bulletin 1998, 21:1251-1257.
27. Liu Z., Tanaka S., Horigome H., Hirano T., Oka K. Induction of apoptosis in human lung fibroblasts and peripheral lymphocytes in vitro by Shosaiko-to derived phenolic metabolites. Biological Pharmaceutical Bulletin 2002, 25:37-41.
28. Lixiang L., Yi S., Tanguy L., Xingfei L., Hong Y., Xiaoxiong Z. Determination of polyphenolic content and antioxidant activity of Kudingcha made from Ilex kudingcha C.J. Tseng. Food Chemistry 2009, 112:35-41.
29. Logendra S., Ribnicky D.M., Yang H., Poulev A., Ma J., Kennelly E.J., Raskin I. Bioassay-guided isolation of aldose reductase inhibitors from Artemisia dracunculus. Phytochemistry 2006, 67:1539-1546.
30. Madureira A.M., Molnar A., Abreu P.M., Molnar J., Ferreira M.J.U. A new sesquiterpene-coumarin ether and a new abietane diterpene and their effects as inhibitors of P-glycoprotein. Planta Medica 2004, 70:828-833.
31. Markgraff F. Flore de Madagascar et des Comores. 169e famille - Apocynacées 1976, Imprimerie officielle, Tananarive.
32. Mauny F., Viel J.F., Roubaux F., Ratsimandresv R., Sellin B. Blood pressure, body max index and socio-economic status in the urban population of Antananarivo (Madagascar). Annals of Tropical Medicine and Parasitology 2003, 97:645-654.
33. Metz H.C. Madagascar: A Country Study 1994, GPO for the Library of Congress, Washington.
34. Modigliani R. Physiopathology of diarrhea. Revue du Praticien 1989, 39:2577-2581.
35. Niitsuma T., Morita S., Hayashi T., Homma M., Oka K. Effects of absorbed components of Saiboku-to on the release of leukotrienes from polymorphonuclear leukocytes of patients with bronchial asthma. Methods and Findings in Experimental and Clinical Pharmacology 2001, 23:99-104.
36. Ragone M.I., Sella M., Conforti P., Volonté M.G., Consolini A.E. The spasmolytic effect of Aloysia citriodora, Palau (South American cedron) is partially due to vitexin but not isovitexin on rat duodenums. Journal of Ethnopharmacology 2007, 113:258-266.
37. Ravaoarinoro M., Rafalimanana C., Coulanges P. Viral etiology of diarrheal diseases in Madagascan children. Archives de l'Institut Pasteur de Madagascar 1986, 52:123-130.
38. Ribnicky D.M., Kuhn P., Pouley A., Logendra S., Zuberi A., Cefalu W.T., Raskin I. Improved absorption and bioactivity of active compounds from an anti-diabetic extract of Artemisia dracunculus L. International Journal of Pharmaceutics 2009, 370:87-92.
39. Rivière C., Nguyen T.H.V., Pieters L., Dejaegher B., Vander Heyden Y., Chau V.M., Quetin-Leclercq J. Polyphenols isolated from antiradical extracts of Mallotus metcalfianus. Phytochemistry 2009, 70:86-94.
40. Sato Y., He J.X., Nagai H., Tani T., Akao T. Isoliquiritigenin, one of the antispasmodic principles of Glycyrrhiza ularensis roots, acts in the lower part of intestine. Biological Pharmaceutical Bulletin 2007, 30:145-149.
41. Severi F., Benvenuti S., Costantino L., Vampa G., Melegari M., Antolini L. Synthesis and activity of a new series of chalcones as aldose reductase inhibitors. European Journal of Medicinal Chemistry 1998, 33:859-866.
42. Schatz G.E. Flore générique des arbres de Madagascar 2001, Royal Botanic Garden/Kew & Missouri Botanical Garden.
43. Tamaki T., Niitsuma T. The clinical effect of Bakumondo-to and the analysis of its urinary excreta: antitussive action of Bakumondo-to in bronchial asthma and its components. Journal of Tokyo Medical University 1999, 57:23-30.
44. Wang L.Q., Chen Y.G., Xu J.J., Liu Y., Li X.M., Zhao Y. Compounds from Viburnum species and their biological activities. Chemistry & Biodiversity 2008, 5:1879-1899.