A new sesquiterpene-coumarin ether and a new abietane diterpene and their effects as inhibitors of P-glycoprotein

Planta Medica

Volumn 70, Issue 9, 2004, Pages 828-833

  Madureira, Ana M ^a   Molnár, Annamária ^b   Abreu, Pedro M ^c   Molnár, Joseph ^b   Ferreira, Maria José U ^a  

^a RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^b UNIVERSITY OF SZEGED   (Hungary)

^c DEPARTAMENTO DE QUÍMICA   (Portugal)

Author keywords

Abietane diterpene; Euphorbia portlandica; Euphorbiaceae; Multidrug resistance; P glycoprotein; Sesquiterpene coumarin; Triterpenes

Indexed keywords

COUMARIN DERIVATIVE; DAVIDIGENIN; DITERPENE; DRIPORTLANDIN; EUPHORBIA PORTLANDICA EXTRACT; FORMONONETIN; GLYCOPROTEIN P INHIBITOR; LUPEOL; NEPEHINOL; PLANT EXTRACT; PORTLANQUINOL; SESQUITERPENE DERIVATIVE; UNCLASSIFIED DRUG; VERAPAMIL; WRIGHTIAL;

ANIMAL CELL; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG ISOLATION; EUPHORBIA PORTLANDICA; LYMPHOMA CELL; MEDICINAL PLANT; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL LINE, TUMOR; COUMARINS; DITERPENES, ABIETANE; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; EUPHORBIA; MICE; P-GLYCOPROTEIN; PHYTOTHERAPY; PLANT COMPONENTS; PLANT EXTRACTS; SESQUITERPENES;

ANIMALIA; EUPHORBIA; EUPHORBIACEAE;

EID: 5444270486     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-827231     Document Type: Article

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