Increased levels of Nε-(carboxymethyl)lysine in epithelial lining fluid from peripheral airways in patients with chronic obstructive pulmonary disease: A pilot study

Clinical Science

Volumn 119, Issue 3, 2010, Pages 143-149

  Kanazawa, Hiroshi ^a   Kodama, Toyoki ^a   Asai, Kazuhisa ^a   Matsumura, Saeko ^a   Hirata, Kazuto ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Bronchoscopic microsampling technique; Chronic obstructive pulmonary disease (COPD); Epithelial lining fluid; N (carboxymethyl)lysine (CML); Small airway

Indexed keywords

8 ISOPROSTANE; BIOLOGICAL MARKER; INTERLEUKIN 8; LYSINE DERIVATIVE; N EPSILON (CARBOXYMETHYL)LYSINE; UNCLASSIFIED DRUG;

AGED; AIRWAY; ARTICLE; BIOCHEMISTRY; BRONCHOSCOPY; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; EPITHELIUM; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HUMAN; LUNG FLUID; MALE; PILOT STUDY; PRIORITY JOURNAL; SMOKING; VALIDITY;

AGED; BRONCHIOLES; BRONCHOSCOPY; DINOPROST; FORCED EXPIRATORY VOLUME; HUMANS; INTERLEUKIN-8; LYSINE; MIDDLE AGED; PILOT PROJECTS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY MUCOSA; SMOKING; SPECIMEN HANDLING; VITAL CAPACITY;

EID: 77954933685     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20100096     Document Type: Article

References (34)

1. Rabe, K. F., Hurd, S., Anzueto, A., Barnes, P. J., Buist, S. A., Calverley, P., Fukuchi, Y., Jenkins, C., Rodriguez-Roisin, R., van Weel, C. and Zielinski, J. (2007) Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. GOLD executive summary. Am. J. Respir. Crit. Care Med. 176, 532-555
2. Hogg, J. C., Chu, F. S. F., Tan, W. C., Sin, D. D., Patel, S. A., Pare, P. D.,Martinez, F. J., Rogers, R. M., Make, B. J., Criner, G. J. et al. (2007) Survival after lung volume reduction in chronic obstructive pulmonary disease. Insights from small airway pathology. Am. J. Respir. Crit. Care Med. 176, 454-459
3. Rice, A. and Nicholson, A. G. (2009) The pathologist's approach to small airways disease. Histopathology 54, 117-133
4. Yoshida, T. and Tuder, R. M. (2007) Pathology of cigarette smoke-induced chronic obstructive pulmonary disease. Physiol. Rev. 87, 1047-1082
5. Brownlee, M. (1995) Advanced glycosylation in diabetes and aging. Annu. Rev. Med. 46, 223-224
6. Baynes, J.W. (1991) Role of oxidative stress in development of complications in diabetes. Diabetes 40, 405-412
7. Morbini, P., Villa, C., Campo, I., Zorzetto, M., Inghilleri, S. and Luisetti, M. (2006) The receptor for advanced glycation end products and its ligands: a new inflammatory pathway in lung disease? Mod. Pathol. 19, 1437-1445
8. ε-(carboxymethyl)lysine levels and percentage of eosinophils in induced sputum for assessment of small airway involvements in asthma. Med. Sci. Monit. 14, CR375-CR380
9. Kodama, T., Kanazawa, H., Tochino, Y., Kyoh, S., Asai, K. and Hirata, K. (2009) A technological advance comparing epithelial lining fluid from different regions of the lung in smokers. Respir. Med. 103, 35-40
10. Ishizaka, A.,Watanabe, M., Yamashita, T., Ogawa, Y., Koh, H., Hasegawa, N., Nakamura, H., Asano, K., Yamaguchi, K., Kotani, M. et al. (2001) New bronchoscopic microsample probe to measure the biochemical constituents in epithelial lining fluid of patients with acute respiratory distress syndrome. Crit. Care Med. 29, 896-898
11. Watanabe, M., Ishizaka, A., Ikeda, E., Ohashi, A. and Kobayashi, K. (2003) Contributions of bronchoscopic microsampling in the supplemental diagnosis of small peripheral lung carcinoma. Ann. Thorac. Surg. 76, 1668-1673
12. ε-(Carboxymethyl)lysine, a major advanced glycation end product, in exhaled breath condensate as a biomarker of small airway involvement in asthma. J. Asthma 44, 861-866
13. Cracowski, J. L., Durand, T. and Bessard, G. (2002) Isoprostanes as a biomarker of lipid peroxidation in human physiology, pharmacology and clinical implications. Trends Pharmacol. Sci. 23, 360-366
14. Shoji, S., Ertl, R. F., Koyama, S., Robbins, R., Leikauf, G., Von Essen, S. and Rennard, S. I. (1995) Cigarette smoke stimulates release of neutrophil chemotactic activity from cultured bovine bronchial epithelial cells. Clin. Sci. 88, 337-344
15. Stefano, A. D., Caramori, G., Ricciardolo, F. L. M., Capelli, A., Adcock, I. M. and Donner, C. F. (2004) Cellular and molecular mechanisms in chronic obstructive pulmonary disease: an overview. Clin. Exp. Allergy 34, 1156-1167
16. Willemse, B. W., Postma, D. S., Timens, W. and ten Hacken, N. H. T. (2004) The impact of smoking cessation on respiratory symptoms, lung function, airway hyperresponsiveness and inflammation. Eur. Respir. J. 23, 464-476
17. Hogg, J. C., Chu, F., Utokaparch, S., Woods, R., Elliot, W. M., Buzatu, L., Cherniack, R. M., Rogers, R. M., Sciurba, F. C., Coxson, H. O. and Pare, P. D. (2004) The nature of small-airway obstruction in chronic obstructive pulmonary disease. N. Engl. J. Med. 350, 2645-2653
18. Morrow, J. D. and Roberts, L. J. I. (2002) The isoprostanes: their role as an index of oxidant stress status in human pulmonary disease. Am. J. Respir. Crit. Care Med. 166, S25-S30
19. Wood, L. G., Garg, M. L., Simpson, J. L., Mori, T. A., Croft, K. D., Wark, P. A. B. and Gibson, P. G. (2005) Induced sputum 8-isoprostane concentrations in inflammatory airway diseases. Am. J. Respir. Crit. Care Med. 171, 426-430
20. Barnes, P. J., Chowdhury, B., Kharitonov, S. A., Magnussen, H., Page, C. P., Postma, D. and Saetta, M. (2006) Pulmonary biomarkers in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 174, 6-14
21. Takizawa, H., Desaki, M., Ohtoshi, T., Kawasaki, S., Kohyama, T., Sato, M., Tanaka, M., Kasama, T., Kobayashi, K., Nakajima, J. and Ito, K. (1997) Erythromycin modulates IL-8 expression in normal and inflamed human bronchial epithelial cells. Am. J. Respir. Crit. Care Med. 156, 266-271
22. Tanino, M., Betsuyaku, T., Takeyabu, K., Tanino, Y., Yamaguchi, E., Miyamoto, K. and Nishimura, M. (2002) Increased levels of interleukin-8 in BAL fluid from smokers susceptible to pulmonary emphysema. Thorax 57, 405-411 (Pubitemid 34494150)
23. Yamamoto, C., Yoneda, T., Yoshikawa, M., Fu, A., Tokuyama, T., Tsukaguchi, K. and Narita, N. (1997) Airway inflammation in COPD assessed by sputum levels of interleukin-8. Chest 112, 505-510 (Pubitemid 27349446)
24. Mio, T., Romberger, D. J., Thompson, A. B., Robbins, R. A., Heires, A. and Rennard, S. I. (1997) Cigarette smoke induces interleukin-8 release from human bronchial epithelial cells. Am. J. Respir. Crit. Care Med. 155, 1770-1776
25. Takizawa, H. (1998) Airway epithelial cells as regulators of airway inflammation. Int. J. Mol. Med. 1, 367-378
26. Takizawa, H., Tanaka, M., Takami, K., Ohtoshi, T., Ito, K., Satoh, M., Okada, Y., Yamasawa, F. and Umeda, A. (2000) Increased expression of inflammatory mediators in small-airway epithelium from tobacco smokers. Am. J. Physiol. Lung Cell. Mol. Physiol. 278, L906-L913
27. Schmidt, A. M., Yan, S. D., Yan, S. F. and Stern, D. M. (2001) The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses. J. Clin. Invest. 108, 949-955
28. Fehrenbach, H., Kasper, M., Tschernig, T., Shearman, M. S., Schuh, D. and Muller, M. (1998) Receptor for advanced glycation endproducts (RAGE) exhibits highly differential cellular and subcellular localisation in rat and human lung. Cell. Mol. Biol. 44, 1147-1157
29. Yan, S. F., Ramasamy, R., Naka, Y. and Schmidt, A. M. (2003) Glycation, inflammation, and RAGE: a scaffold for the macrovascular complications of diabetes and beyond. Circ. Res. 93, 1159-1169
30. Repapi, E., Sayers, I., Wain, L. V., Burton, P. R., Johnson, T., Obeidat, M., Zhao, J. H., Ramasamy, A., Zhai, G., Vitart, V. et al. (2010) Genome-wide association study identifies five loci associated with lung function. Nat. Genet. 42, 36-44
31. Hancock, D. B., Eijgelsheim, M., Wilk, J. B., Gharib, S. A., Loehr, L. R., Marciante, K. D., Franceschini, N., van Durme, Y. M., Chen, T. H., Barr, R. G. et al. (2010) Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat. Genet. 42, 45-52
32. ε-(Carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression. J. Biol. Chem. 274, 31740-31749
33. Senftleben, U. and Karin, M. (2002) The IKK/NF-κB pathway. Crit. Care Med. 30, S18-S26
34. Hoffman, E., Dittrich-Breiholz, O., Holtmann, H. and Kracht, M. (2002) Multiple control of interleukin-8 gene expression. J. Leukocyte Biol. 72, 847-855 (Pubitemid 35365158)