Crystal structure of α-COP in complex with ε-COP provides insight into the architecture of the COPI vesicular coat

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 25, 2010, Pages 11271-11276

  Hsia, Kuo Chiang ^a   Hoelz, André ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Coatomer; Interaction studies; Membrane coat; Tetratricopeptide repeat (TPR); U shaped helical solenoid

Indexed keywords

ALPHA COAT PROTEIN COMPLEX; COAT PROTEIN COMPLEX I; EPSILON COAT PROTEIN COMPLEX; UNCLASSIFIED DRUG; COATOMER PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; NONHUMAN; PRIORITY JOURNAL; TETRATRICOPEPTIDE REPEAT; AMINO ACID SEQUENCE; CELL MEMBRANE; CHEMISTRY; COATED VESICLE; DIMERIZATION; ESCHERICHIA COLI; METABOLISM; METHODOLOGY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SACCHAROMYCES CEREVISIAE; TWO HYBRID SYSTEM; X RAY CRYSTALLOGRAPHY;

SOLENOIDEA;

CELL MEMBRANE; COAT PROTEIN COMPLEX I; COATOMER PROTEIN; COP-COATED VESICLES; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ESCHERICHIA COLI; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; REPETITIVE SEQUENCES, AMINO ACID; SACCHAROMYCES CEREVISIAE; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 77954915341     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1006297107     Document Type: Article

References (41)

1. Kirchhausen T (2000) Three ways to make a vesicle. Nat Rev Mol Cell Biol 1:187-198.
2. Springer S, Spang A, Schekman R (1999) A primer on vesicle budding. Cell 97:145-148.
3. Orci L, Glick BS, Rothman JE (1986) A new type of coated vesicular carrier that appears not to contain clathrin: its possible role in protein transport within the Golgi stack. Cell 46:171-184.
4. Malhotra V, Serafini T, Orci L, Shepherd JC, Rothman JE (1989) Purification of a novel class of coated vesicles mediating biosynthetic protein transport through the Golgi stack. Cell 58:329-336.
5. Serafini T, et al. (1991) A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein beta-adaptin. Nature 349:215-220.
6. Waters MG, Serafini T, Rothman JE (1991) "Coatomer": a cytosolic protein complex containing subunits of non-clathrin-coated Golgi transport vesicles. Nature 349:248-251.
7. Hara-Kuge S, et al. (1994) En bloc incorporation of coatomer subunits during the assembly of COP-coated vesicles. J Cell Biol 124:883-892.
8. Kuge O, et al. (1993) zeta-COP, a subunit of coatomer, is required for COP-coated vesicle assembly. J Cell Biol 123:1727-1734.
9. Stenbeck G, et al. (1993) beta′-COP, a novel subunit of coatomer. EMBO J 12:2841-2845.
10. Stenbeck G, et al. (1992) Gamma-COP, a coat subunit of non-clathrin-coated vesicles with homology to Sec21p. FEBS Lett 314:195-198.
11. Hosobuchi M, Kreis T, Schekman R (1992) SEC21 is a gene required for ER to Golgi protein transport that encodes a subunit of a yeast coatomer. Nature 360:603-605.
12. Duden R, et al. (1994) Yeast beta-and beta′-coat proteins (COP). Two coatomer subunits essential for endoplasmic reticulum-to-Golgi protein traffic. J Biol Chem 269:24486-24495.
13. Letourneur F, et al. (1994) Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum. Cell 79:1199-1207.
14. Cosson P, Démollière C, Hennecke S, Duden R, Letourneur F (1996) Delta- and zeta-COP, two coatomer subunits homologous to clathrin-associated proteins, are involved in ER retrieval. EMBO J 15:1792-1798.
15. Duden R, Kajikawa L, Wuestehube L, Schekman R (1998) epsilon-COP is a structural component of coatomer that functions to stabilize alpha-COP. EMBO J 17:985-995.
16. Serafini T, et al. (1991) ADP-ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: a novel role for a GTP-binding protein. Cell 67:239-253.
17. Gaynor EC, Graham TR, Emr SD (1998) COPI in ER/Golgi and intra-Golgi transport: do yeast COPI mutants point the way? Biochim Biophys Acta 1404:33-51.
18. Fiedler K, Veit M, Stamnes MA, Rothman JE (1996) Bimodal interaction of coatomer with the p24 family of putative cargo receptors. Science 273:1396-1399.
19. Lowe M, Kreis TE (1996) in Vivo assembly of coatomer, the COP-I coat precursor. J Biol Chem 271:30725-30730.
20. Faulstich D, et al. (1996) Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex. J Cell Biol 135:53-61.
21. Eugster A, Frigerio G, Dale M, Duden R (2000) COP I domains required for coatomer integrity, and novel interactions with ARF and ARF-GAP. EMBO J 19:3905-3917.
22. Schledzewski K, Brinkmann H, Mendel RR (1999) Phylogenetic analysis of components of the eukaryotic vesicle transport system reveals a common origin of adaptor protein complexes 1, 2, and 3 and the F subcomplex of the coatomer COPI. J Mol Evol 48:770-778.
23. Hoffman GR, Rahl PB, Collins RN, Cerione RA (2003) Conserved structural motifs in intracellular trafficking pathways: structure of the gammaCOP appendage domain. Mol Cell 12:615-625.
24. Watson PJ, Frigerio G, Collins BM, Duden R, Owen DJ (2004) Gamma-COP appendage domain - structure and function. Traffic 5:79-88.
25. Yu W, Lin J, Jin C, Xia B (2009) Solution structure of human zeta-COP: direct evidences for structural similarity between COP I and clathrin-adaptor coats. J Mol Biol 386:903-912.
26. Sun Z, et al. (2007) Multiple and stepwise interactions between coatomer and ADP-ribosylation factor-1(Arf1)-GTP. Traffic 8:582-593.
27. Blatch GL, Laessle M (1999) The tetratricopeptide repeat: a structural motif mediating protein-protein interactions. Bioessays 21:932-939.
28. Wang J, Dye BT, Rajashankar KR, Kurinov I, Schulman BA (2009) Insights into anaphase promoting complex TPR subdomain assembly from a CDC26-APC6 structure. Nat Struct Mol Biol 16:987-989.
29. Fath S, Mancias JD, Bi X, Goldberg J (2007) Structure and organization of coat proteins in the COPII cage. Cell 129:1325-1336.
30. Hsia KC, Stavropoulos P, Blobel G, Hoelz A (2007) Architecture of a coat for the nuclear pore membrane. Cell 131:1313-1326.
31. Debler EW, et al. (2008) A fence-like coat for the nuclear pore membrane. Mol Cell 32:815-826.
32. Brohawn SG, Leksa NC, Spear ED, Rajashankar KR, Schwartz TU (2008) Structural evidence for common ancestry of the nuclear pore complex and vesicle coats. Science 322:1369-1373.
33. Andag U, Schmitt HD (2003) Dsl1p, an essential component of the Golgi-endoplasmic reticulum retrieval system in yeast, uses the same sequence motif to interact with different subunits of the COPI vesicle coat. J Biol Chem 278:51722-51734.
34. Zink S, Wenzel D, Wurm CA, Schmitt HD (2009) A link between ER tethering and COP-I vesicle uncoating. Dev Cell 17:403-416.
35. Kraynack BA, et al. (2005) Dsl1p, Tip20p, and the novel Dsl3(Sec39) protein are required for the stability of the Q/t-SNARE complex at the endoplasmic reticulum in yeast. Mol Biol Cell 16:3963-3977.
36. Ren Y, et al. (2009) A structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsl1. Cell 139:1119-1129.
37. Blobel G (1980) Intracellular protein topogenesis. Proc Natl Acad Sci USA 77:1496-1500.
38. Devos D, et al. (2004) Components of coated vesicles and nuclear pore complexes share a common molecular architecture. PLoS Biol 2:e380.
39. Bi X, Mancias JD, Goldberg J (2007) Insights into COPII coat nucleation from the structure of Sec23. Sar1 complexed with the active fragment of Sec 31. Dev Cell 13:635-645.
40. Hoelz A, Nairn AC, Kuriyan J (2003) Crystal structure of a tetradecameric assembly of the association domain of Ca2+/calmodulin-dependent kinase II. Mol Cell 11:1241-1251.
41. Zink S, Wenzel D, Wurm CA, Schmitt HD (2009) A link between ER tethering and COP-I vesicle uncoating. Dev Cell 17:403-416.