Reduction in cholesterol synthesis in response to serum starvation in lymphoblasts of a patient with barth syndrome1

Biochemistry and Cell Biology

Volumn 88, Issue 4, 2010, Pages 595-602

  Hauff, Kristin D ^a   Hatch, Grant M ^b  

^a Department of Pharmacology and Therapeutics ^*  (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Barth syndrome; Cholesterol synthesis; Human lymphoblasts; Uafazzin

Indexed keywords

CHOLESTEROL LEVELS; CHOLESTEROL SYNTHESIS; COENZYME A; CONTROL-CELL; CULTURE CONDITIONS; ELEVATED LEVEL; HYDROXYMETHYLGLUTARYL; IN-CONTROL; MESSENGER RNA; PYRUVATES; REDUCTASE ACTIVITY; REDUCTASE ENZYMES; SERUM STARVATION;

BIOCHEMISTRY; BIOSYNTHESIS; BODY FLUIDS; CELL CULTURE; ENZYME ACTIVITY; RNA;

CHOLESTEROL;

CARBON 14; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; MESSENGER RNA; PYRUVIC ACID;

ARTICLE; BARTH SYNDROME; CELL STIMULATION; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; ENZYME ACTIVITY; LYMPHOBLAST; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION;

ACETIC ACID; ATP-BINDING CASSETTE TRANSPORTERS; BARTH SYNDROME; CARBON RADIOISOTOPES; CELLS, CULTURED; CHOLESTEROL; CULTURE MEDIA, SERUM-FREE; GENE DELETION; GENE EXPRESSION REGULATION; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; LYMPHOCYTES; PYRUVIC ACID; RECEPTORS, LDL; STARVATION; TRANSCRIPTION FACTORS;

EID: 77954908023     PISSN: 08298211     EISSN: 12086002     Source Type: Journal    
DOI: 10.1139/O09-186     Document Type: Article

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