Does leptin predict incident hypertension in older adults?: ORIGINAL ARTICLE

Clinical Endocrinology

Volumn 73, Issue 2, 2010, Pages 201-205

  Kramer, Caroline K ^a,b   Von Mühlen, Denise ^a   Barrett Connor, Elizabeth ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN;

AGED; ARTICLE; BODY MASS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; OBESITY; PRIORITY JOURNAL; RADIOIMMUNOASSAY; SYSTOLIC BLOOD PRESSURE;

ADULT; AGED; AGED, 80 AND OVER; DIAGNOSTIC TECHNIQUES, ENDOCRINE; FEMALE; HUMANS; HYPERTENSION; INCIDENCE; LEPTIN; MALE; MIDDLE AGED; PROGNOSIS;

EID: 77954878733     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2010.03781.x     Document Type: Article

References (25)

1. van Dijk, G. (2001) The role of leptin in the regulation of energy balance and adiposity. Journal of Neuroendocrinology, 13, 913 921.
2. Haynes, W.G., Sivitz, W.I., Morgan, D.A. et al. (1997) Sympathetic and cardiorenal actions of leptin. Hypertension, 30, 619 623.
3. Shek, E.W., Brands, M.W. Hall, J.E. (1998) Chronic leptin infusion increases arterial pressure. Hypertension, 31, 409 414.
4. Barba, G., Russo, O., Siani, A. et al. (2003) Plasma leptin and blood pressure in men: graded association independent of body mass and fat pattern. Obesity Research, 11, 160 166.
5. Takizawa, H., Ura, N., Saitoh, S. et al. (2001) Gender difference in the relationships among hyperleptinemia, hyperinsulinemia, and hypertension. Clinical and Experimental Hypertension, 23, 357 368.
6. Masuo, K., Mikami, H., Itoh, M. et al. (2000) Sympathetic activity and body mass index contribute to blood pressure levels. Hypertension Research, 23, 303 310.
7. Genelhu, V.A., Celoria, B.M., Pimentel, M.M. et al. (2009) Association of a common variant of the leptin gene with blood pressure in an obese Brazilian population. American Journal of Hypertension, 22, 577 580.
8. Ma, D., Feitosa, M.F., Wilk, J.B. et al. (2009) Leptin is associated with blood pressure and hypertension in women from the National Heart, Lung, and Blood Institute Family Heart Study. Hypertension, 53, 473 479.
9. Galletti, F., D'Elia, L., Barba, G. et al. (2008) High-circulating leptin levels are associated with greater risk of hypertension in men independently of body mass and insulin resistance: results of an eight-year follow-up study. Journal of Clinical Endocrinology and Metabolism, 93, 3922 3926.
10. Barrett-Connor, E. (1980) The prevalence of diabetes mellitus in an adult community as determined by history or fasting hyperglycemia. American Journal of Epidemiology, 111, 705 712.
11. Chobanian, A.V., Bakris, G.L., Black, H.R. et al. (2003) The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA, 289, 2560 2572.
12. The hypertension detection and follow-up program (1976) The hypertension detection and follow-up program: hypertension detection and follow-up program cooperative group. Preventive Medicine, 5, 207 215.
13. Cockcroft, D.W. Gault, M.H. (1976) Prediction of creatinine clearance from serum creatinine. Nephron, 16, 31 41.
14. Bonora, E., Targher, G., Alberiche, M. et al. (2000) Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity. Diabetes Care, 23, 57 63.
15. Lindgarde, F., Soderberg, S., Olsson, T. et al. (2001) Overweight is associated with lower serum leptin in Peruvian Indian than in Caucasian women: a dissociation contributing to low blood pressure? Metabolism, 50, 325 329.
16. Hu, F.B., Chen, C., Wang, B. et al. (2001) Leptin concentrations in relation to overall adiposity, fat distribution, and blood pressure in a rural Chinese population. International Journal of Obesity and Related Metabolic Disorders, 25, 121 125.
17. Beltowski, J. (2006) Role of leptin in blood pressure regulation and arterial hypertension. Journal of Hypertension, 24, 789 801.
18. Rahmouni, K., Jalali, A., Morgan, D.A. et al. (2005) Lack of dilator effect of leptin in the hindlimb vascular bed of conscious rats. European Journal of Pharmacology, 518, 175 181.
19. De Rosa, S., Cirillo, P., Pacileo, M. et al. (2009) Leptin Stimulated C-Reactive Protein Production by Human Coronary Artery Endothelial Cells. Journal of Vascular Research, 46, 609 617.
20. Bluher, S. Mantzoros, C.S. (2009) Leptin in humans: lessons from translational research. American Journal of Clinical Nutrition, 89, 991S 997S.
21. Farooqi, I.S., Matarese, G., Lord, G.M. et al. (2002) Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrinemetabolic dysfunction of human congenital leptin deficiency. Journal of Clinical Investigation, 110, 1093 1103.
22. Ebihara, K., Kusakabe, T., Hirata, M. et al. (2007) Efficacy and safety of leptin-replacement therapy and possible mechanisms of leptin actions in patients with generalized lipodystrophy. Journal of Clinical Endocrinology and Metabolism, 92, 532 541.
23. Mulligan, K., Khatami, H., Schwarz, J.M. et al. (2009) The effects of recombinant human leptin on visceral fat, dyslipidemia, and insulin resistance in patients with human immunodeficiency virus-associated lipoatrophy and hypoleptinemia. Journal of Clinical Endocrinology and Metabolism, 94, 1137 1144.
24. Gavrila, A., Chan, J.L., Yiannakouris, N. et al. (2003) Serum adiponectin levels are inversely associated with overall and central fat distribution but are not directly regulated by acute fasting or leptin administration in humans: cross-sectional and interventional studies. Journal of Clinical Endocrinology and Metabolism, 88, 4823 4831.
25. Thomopoulos, C., Papadopoulos, D.P., Papazachou, O. et al. (2009) Free leptin is associated with masked hypertension in nonobese subjects: a cross-sectional study. Hypertension, 53, 965 972.