Croton tonkinensis; ent kaurane diterpenoid; ent 11 acetoxy 7 hydroxykaur 16 en 15 one; Euphorbiaceae; SIRT1
Indexed keywords
CROTON EXTRACT;
CROTON TONKINENSIS EXTRACT;
DITERPENOID;
ENT 11ALPHA ACETOXY 7BETA HYDROXYKAUR 16 EN 15 ONE;
ENT 11ALPHA ACETOXYKAUR 16 EN 18 OIC ACID;
ENT 18 ACETOXY 11ALPHA HYDROXYKAUR 16 EN 15 ONE;
ENT 18 ACETOXY 7ALPHA,14BETA DIHYDROXYKAUR 16 EN 15 ONE;
ENT 18 ACETOXY 7BETA HYDROXYKAUR 15 ONE;
ENT 1ALPHA,14ALPHA DIACETOXY 7BETA HYDROXYKAUR 16 EN 15 ONE;
ENT 1ALPHA,7BETA DIACETOXY 14ALPHA HYDROXYKAUR 16 EN 15 ONE;
ENT 1ALPHA,7BETA,14ALPHA TRIACETOXY KAUR 16 EN 15 ONE;
ENT 1BETA ACETOXY 7ALPHA,14BETA DIHYDROXYKAUR 16 EN 15 ONE;
ENT 7ALPHA,14BETA DIHYDROXYKAUR 16 EN 15 ONE;
ENT 7BETA HYDROXY 15 OXOKAUR 16 EN 18 OL;
ENT 7BETA HYDROXY 15 OXOKAUR 16 EN 18 YL ACETATE;
SIRTUIN 1;
UNCLASSIFIED DRUG;
ARTICLE;
BIOASSAY;
CONTROLLED STUDY;
CROTON;
CROTON TONKINENSIS;
CRYSTALLIZATION;
DRUG STRUCTURE;
FRACTIONATION;
IC 50;
IN VITRO STUDY;
ISOLATION PROCEDURE;
MEDICINAL PLANT;
NONHUMAN;
NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;
PLANT LEAF;
HSIR1 (SIRT1) functions as an NAD-dependent p53 deacetylase
Vaziri H, Dessain S K., Ng Eaton E, Imai S I., Frye R A., Pandita T K., Guarente L, Weinberg R A. hSIR1 (SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 2001 107 149-159
Modulation of NF-B-dependent transcription and cell survival by the SIRT1 deacetylase
Yeung F, Hoberg J E., Ramsey C S., Keller M D., Jones D R., Frye R A., Mayo M W. Modulation of NF-B-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J 2004 23 2369-2380
Identification of a class of small molecule inhibitors of the Sirtuin family of NAD-dependent deacetylases by phenotypic screening
Grozinger C M., Chao E D., Blackwell H E., Moazed D, Schreiber S L. Identification of a class of small molecule inhibitors of the Sirtuin family of NAD-dependent deacetylases by phenotypic screening. J Biol Chem 2001 276 38837-38843
Ent -Kaurane diterpenoids from Croton tonkinesis inhibit LPS-induced NF- B activation and NO production
Giang P M., Jin H Z., Son P T., Lee J H., Hong Y S., Lee J J. ent -Kaurane diterpenoids from Croton tonkinesis inhibit LPS-induced NF- B activation and NO production. J Nat Prod 2003 66 1217-1220
Cytotoxic diterpenoids from Vietnamese medicinal plant Croton tonkinensis Gagnep
Giang P M., Phan T S., Hamada Y, Otsuka H. Cytotoxic diterpenoids from Vietnamese medicinal plant Croton tonkinensis Gagnep. Chem Pharm Bull 2005 53 296-300
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast Sir2 and human SIRT1
Bitterman K J., Anderson R M., Cohen H Y., Latorre-Esteves M, Sinclair D A. Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast Sir2 and human SIRT1. J Biol Chem 2002 277 45099-45107
11-Oxygenated cytotoxic 8,9-secokauranes from a New Zealand liverwort, Lepidolaena taylorii
Perry N B., Burgess E J., Baek S H., Weavers R T., Geis W, Mauger A B. 11-Oxygenated cytotoxic 8,9-secokauranes from a New Zealand liverwort, Lepidolaena taylorii. Phytochemistry 1999 50 423-433