Validation of a liquid chromatography-tandem mass spectrometric assay for the quantitative determination of hydrastine and berberine in human serum

Journal of Pharmaceutical and Biomedical Analysis

Volumn 49, Issue 4, 2009, Pages 1021-1026

  Gupta, Prem K ^a   Hubbard, Martha ^a   Gurley, Bill ^a   Hendrickson, Howard P ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Berberine; Clinical pharmacokinetics; Goldenseal; Hydrastine; LC MS MS

Indexed keywords

BERBERINE; GOLDENSEAL EXTRACT; HYDRASTINE; NOSCAPINE; PLANT EXTRACT; UNCLASSIFIED DRUG;

ACCURACY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG HALF LIFE; DRUG STABILITY; DRUG STRUCTURE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; HYDRASTIS; LIQUID CHROMATOGRAPHY; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; PRIORITY JOURNAL; QUALITY CONTROL; SINGLE DRUG DOSE; STANDARD; TANDEM MASS SPECTROMETRY;

BENZYLISOQUINOLINES; BERBERINE; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIETARY SUPPLEMENTS; HUMANS; INDICATORS AND REAGENTS; QUALITY CONTROL; REPRODUCIBILITY OF RESULTS; SOLVENTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 62749172350     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.01.036     Document Type: Article

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