Development of silymarin self-microemulsifying drug delivery system with enhanced oral bioavailability

AAPS PharmSciTech

Volumn 11, Issue 2, 2010, Pages 672-678

  Li, Xinru ^a   Yuan, Quan ^b   Huang, Yanqing ^a   Zhou, Yanxia ^a   Liu, Yan ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b Beijing DMS Pharma Ltd   (China)

Author keywords

Bioavailability; Microemulsion; Self microemulsifying drug delivery system; Silymarin

Indexed keywords

ALCOHOL; CREMOPHOR; LINOLEIC ACID ETHYL ESTER; SILIBININ; SILYMARIN; SODIUM CHLORIDE; ANTIOXIDANT; DRUG CARRIER; EMULSION;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOG; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG CAPSULE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; HYDROPHILICITY; LIGHT SCATTERING; MALE; MICROEMULSION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; SINGLE DRUG DOSE; SOLUBILIZATION; ADMINISTRATION AND DOSAGE; ANIMAL; CHEMISTRY; EMULSION; ORAL DRUG ADMINISTRATION; PROCEDURES; SOLUBILITY; SYNTHESIS;

ADMINISTRATION, ORAL; ANIMALS; ANTIOXIDANTS; DOGS; DRUG CARRIERS; DRUG COMPOUNDING; EMULSIONS; SILYMARIN; SOLUBILITY;

EID: 77954815821     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-010-9432-x     Document Type: Article

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