Preparation of silymarin proliposome: A new way to increase oral bioavailability of silymarin in beagle dogs

International Journal of Pharmaceutics

Volumn 319, Issue 1-2, 2006, Pages 162-168

  Yan yu, Xiao ^a   Yun mei, Song ^a   Zhi peng, Chen ^a   Qi neng, Ping ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Beagle dogs; Oral bioavailability; Pharmacokinetics; Proliposome; Silymarin

Indexed keywords

LIPOSOME; PHOSPHATIDYLCHOLINE; SILIBININ; SILYMARIN;

ANIMAL EXPERIMENT; ARTICLE; COMPARTMENT MODEL; CONTROLLED STUDY; DOG; DRUG ADSORPTION; DRUG BIOAVAILABILITY; DRUG STABILITY; DRUG SYNTHESIS; GASTROINTESTINAL ABSORPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SUSPENSION; TRANSMISSION ELECTRON MICROSCOPY;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; DOGS; DRUG COMPOUNDING; DRUG STABILITY; HYDROGEN-ION CONCENTRATION; LIPOSOMES; MALE; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, BIOLOGICAL; PARTICLE SIZE; PROTECTIVE AGENTS; SILYMARIN; SOLUBILITY;

EID: 33745891184     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.03.037     Document Type: Article

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