메뉴 건너뛰기




Volumn 130, Issue 8, 2010, Pages 1971-1987

Biomarkers: The useful and the not so useful an assessment of molecular prognostic markers for Cutaneous melanoma

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; BETA CATENIN; BETA3 INTEGRIN; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CD51 ANTIGEN; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FRIZZLED PROTEIN; GROWTH DIFFERENTIATION FACTOR 15; HEAT SHOCK PROTEIN 90; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; MYC PROTEIN; NERVE GROWTH FACTOR; PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN MLH1; PROTEIN S100B; SECURIN; SOMATOMEDIN BINDING PROTEIN 2; SOMATOMEDIN BINDING PROTEIN 4; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR EZH2; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA2; TUMOR MARKER; UNINDEXED DRUG; UVOMORULIN; VASCULOTROPIN A;

EID: 77954760173     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2010.149     Document Type: Article
Times cited : (41)

References (257)
  • 1
    • 33744513575 scopus 로고    scopus 로고
    • Sorafenib (BAY 43-9006, Nexavar((R))), a dual-action inhibitor that targets RAF/MEK/ERK pathway in tumor cells and tyrosine kinases VEGFR/ PDGFR in tumor vasculature
    • Adnane L, Trail PA, Taylor I, et al. (2005) Sorafenib (BAY 43-9006, Nexavar((R))), a dual-action inhibitor that targets RAF/MEK/ERK pathway in tumor cells and tyrosine kinases VEGFR/ PDGFR in tumor vasculature. Methods En-zymol 407:597-612
    • (2005) Methods En-zymol , vol.407 , pp. 597-612
    • Adnane, L.1    Trail, P.A.2    Taylor, I.3
  • 2
    • 0035132865 scopus 로고    scopus 로고
    • CD44 is the principal mediator of hyaluronic-acid-induced melanoma cell proliferation
    • Ahrens T, Assmann V, Fieber C, et al. (2001) CD44 is the principal mediator of hyaluronic-acid-induced melanoma cell proliferation. J Invest Dermatol 116:93-101
    • (2001) J Invest Dermatol , vol.116 , pp. 93-101
    • Ahrens, T.1    Assmann, V.2    Fieber, C.3
  • 3
    • 1542574206 scopus 로고    scopus 로고
    • Progression in cutaneous malignant melanoma is associated with distinct expression profiles: A tissue microarray-based study
    • Alonso SR, Ortiz P, Pollan M et al. (2004) Progression in cutaneous malignant melanoma is associated with distinct expression profiles: a tissue microarray-based study. Am J Pathol 164:193-203
    • (2004) Am J Pathol , vol.164 , pp. 193-203
    • Alonso, S.R.1    Ortiz, P.2    Pollan, M.3
  • 4
    • 38949129112 scopus 로고    scopus 로고
    • Activation of CCR9/CCL25 in cutaneous melanoma mediates preferential metastasis to the small intestine
    • Amersi FF, Terando AM, Goto Y et al. (2008) Activation of CCR9/CCL25 in cutaneous melanoma mediates preferential metastasis to the small intestine. Clin Cancer Res 14:638-645
    • (2008) Clin Cancer Res , vol.14 , pp. 638-645
    • Amersi, F.F.1    Terando, A.M.2    Goto, Y.3
  • 5
    • 3342877481 scopus 로고    scopus 로고
    • Expression of S100A4 combined with reduced E-cadherin expression predicts patient outcome in malignant melanoma
    • Andersen K, Nesland JM, Holm R et al. (2004) Expression of S100A4 combined with reduced E-cadherin expression predicts patient outcome in malignant melanoma. Mod Pathol 17:990-997
    • (2004) Mod Pathol , vol.17 , pp. 990-997
    • Andersen, K.1    Nesland, J.M.2    Holm, R.3
  • 6
    • 34250335270 scopus 로고    scopus 로고
    • L576P KIT mutation in anal melanomas correlates with KIT protein expression and is sensitive to specific kinase inhibition
    • Antonescu CR, Busam KJ, Francone TD et al. (2007) L576P KIT mutation in anal melanomas correlates with KIT protein expression and is sensitive to specific kinase inhibition. Int J Cancer 121:257-264
    • (2007) Int J Cancer , vol.121 , pp. 257-264
    • Antonescu, C.R.1    Busam, K.J.2    Francone, T.D.3
  • 7
    • 33751566354 scopus 로고    scopus 로고
    • TANGO is a tumor suppressor of malignant melanoma
    • Arndt S, Bosserhoff AK (2006) TANGO is a tumor suppressor of malignant melanoma. Int J Cancer 119:2812-2820
    • (2006) Int J Cancer , vol.119 , pp. 2812-2820
    • Arndt, S.1    Bosserhoff, A.K.2
  • 8
    • 58149138892 scopus 로고    scopus 로고
    • Adjuvant therapy of melanoma with interferon: Lessons of the past decade
    • Ascierto PA, Kirkwood JM (2008) Adjuvant therapy of melanoma with interferon: lessons of the past decade. J Transl Med 6:62
    • (2008) J Transl Med , vol.6 , pp. 62
    • Ascierto, P.A.1    Kirkwood, J.M.2
  • 9
    • 33644822360 scopus 로고    scopus 로고
    • EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast
    • Bachmann IM, Halvorsen OJ, Collett K et al. (2006) EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast. J Clin Oncol 24:268-273
    • (2006) J Clin Oncol , vol.24 , pp. 268-273
    • Bachmann, I.M.1    Halvorsen, O.J.2    Collett, K.3
  • 10
    • 60649109166 scopus 로고    scopus 로고
    • Tumor necrosis is associated with increased alphavbeta3 integrin expression and poor prognosis in nodular cutaneous melanomas
    • Bachmann IM, Ladstein RG, Straume O et al. (2008) Tumor necrosis is associated with increased alphavbeta3 integrin expression and poor prognosis in nodular cutaneous melanomas. BMC Cancer 8:362
    • (2008) BMC Cancer , vol.8 , pp. 362
    • Bachmann, I.M.1    Ladstein, R.G.2    Straume, O.3
  • 11
    • 16644400331 scopus 로고    scopus 로고
    • Altered expression of cell cycle regulators Cyclin D1, p14, p16, CDK4 and Rb in nodular melanomas
    • Bachmann IM, Straume O, Akslen LA (2004) Altered expression of cell cycle regulators Cyclin D1, p14, p16, CDK4 and Rb in nodular melanomas. Int JOncol 25:1559-1565
    • (2004) Int J Oncol , vol.25 , pp. 1559-1565
    • Bachmann, I.M.1    Straume, O.2    Akslen, L.A.3
  • 12
    • 29344459785 scopus 로고    scopus 로고
    • Importance of P-cadherin, beta-cate-nin, and Wnt5a/frizzled for progression of melanocytic tumors and prognosis in cutaneous melanoma
    • Bachmann IM, Straume O, Puntervoll HE et al. (2005) Importance of P-cadherin, beta-cate-nin, and Wnt5a/frizzled for progression of melanocytic tumors and prognosis in cutaneous melanoma. Clin Cancer Res 11:8606-8614
    • (2005) Clin Cancer Res , vol.11 , pp. 8606-8614
    • Bachmann, I.M.1    Straume, O.2    Puntervoll, H.E.3
  • 13
    • 1242271205 scopus 로고    scopus 로고
    • Endothelin B receptor blockade inhibits dynamics of cell interactions and communications in melanoma cell progression
    • DOI 10.1158/0008-5472.CAN-03-2344
    • Bagnato A, Rosano L, Spinella F et al. (2004) Endothelin B receptor blockade inhibits dynamics of cell interactions and communications in melanoma cell progression. Cancer Res 64:1436-1443 (Pubitemid 38235614)
    • (2004) Cancer Research , vol.64 , Issue.4 , pp. 1436-1443
    • Bagnato, A.1    Rosano, L.2    Spinella, F.3    Di Castro, V.4    Tecce, R.5    Natali, P.G.6
  • 14
    • 0035880957 scopus 로고    scopus 로고
    • Prognostic factors analysis of 17,600 melanoma patients: Validation of the American Joint Committee on Cancer melanoma staging system
    • Balch CM, Soong SJ, Gershenwald JE, et al. (2001) Prognostic factors analysis of 17,600 melanoma patients: validation of the American Joint Committee on Cancer melanoma staging system. J Clin Oncol 19:3622-3634
    • (2001) J Clin Oncol , vol.19 , pp. 3622-3634
    • Balch, C.M.1    Soong, S.J.2    Gershenwald, J.E.3
  • 15
    • 0037179864 scopus 로고    scopus 로고
    • The HtrA1 serine protease is down-regulated during human melanoma progression and represses growth of metastatic melanoma cells
    • Baldi A, De Luca A, Morini M et al. (2002) The HtrA1 serine protease is down-regulated during human melanoma progression and represses growth of metastatic melanoma cells. Oncogene 21:6684-6688
    • (2002) Oncogene , vol.21 , pp. 6684-6688
    • Baldi, A.1    De Luca, A.2    Morini, M.3
  • 16
    • 20944435524 scopus 로고    scopus 로고
    • Ferritin contributes to melanoma progression by modulating cell growth and sensitivity to oxidative stress
    • Baldi A, Lombardi D, Russo P et al. (2005) Ferritin contributes to melanoma progression by modulating cell growth and sensitivity to oxidative stress. Clin Cancer Res 11:3175-3183
    • (2005) Clin Cancer Res , vol.11 , pp. 3175-3183
    • Baldi, A.1    Lombardi, D.2    Russo, P.3
  • 17
    • 0034759481 scopus 로고    scopus 로고
    • Expression of AP-2 transcription factor and of its downstream target genes c-kit, E-cadherin and p21 in human cutaneous melanoma
    • Baldi A, Santini D, Battista T et al. (2001) Expression of AP-2 transcription factor and of its downstream target genes c-kit, E-cadherin and p21 in human cutaneous melanoma. J Cell Biochem 83:364-372
    • (2001) J Cell Biochem , vol.83 , pp. 364-372
    • Baldi, A.1    Santini, D.2    Battista, T.3
  • 18
    • 10744220426 scopus 로고    scopus 로고
    • Analysis of APAF-1 expression in human cutaneous melanoma progression
    • Baldi A, Santini D, Russo P et al. (2004) Analysis of APAF-1 expression in human cutaneous melanoma progression. Exp Dermatol 13:93-97
    • (2004) Exp Dermatol , vol.13 , pp. 93-97
    • Baldi, A.1    Santini, D.2    Russo, P.3
  • 19
    • 0037636740 scopus 로고    scopus 로고
    • Heterogenous S-100B protein expression patterns in malignant melanoma and association with serum protein levels
    • DOI 10.1159/000070296
    • Banfalvi T, Udvarhelyi N, Orosz Z et al. (2003) Heterogenous S-100B protein expression patterns in malignant melanoma and association with serum protein levels. Oncology 64:374-379 (Pubitemid 36682951)
    • (2003) Oncology , vol.64 , Issue.4 , pp. 374-379
    • Banfalvi, T.1    Udvarhelyi, N.2    Orosz, Z.3    Gergye, M.4    Gilde, K.5    Timar, J.6
  • 20
    • 32944457941 scopus 로고    scopus 로고
    • Tumor antigen expression in melanoma varies according to antigen and stage
    • Barrow C, Browning J, MacGregor D et al. (2006) Tumor antigen expression in melanoma varies according to antigen and stage. Clin Cancer Res 12:764-771
    • (2006) Clin Cancer Res , vol.12 , pp. 764-771
    • Barrow, C.1    Browning, J.2    MacGregor, D.3
  • 21
    • 33847690620 scopus 로고    scopus 로고
    • Expression of cell cycle and apoptosis regulatory proteins and telomerase in mela-nocitic lesions
    • Batinac T, Hadzisejdic I, Brumini G et al. (2007) Expression of cell cycle and apoptosis regulatory proteins and telomerase in mela-nocitic lesions. Coll Antropol 31(Suppl 1):17-22
    • (2007) Coll Antropol , vol.31 , Issue.1 SUPPL. , pp. 17-22
    • Batinac, T.1    Hadzisejdic, I.2    Brumini, G.3
  • 22
    • 0032839043 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression in malignant melanoma: Prognostic versus diagnostic usefulness
    • Bayer-Garner IB, Hough AJ Jr, Smoller BR (1999) Vascular endothelial growth factor expression in malignant melanoma: prognostic versus diagnostic usefulness. Mod Patho 12:770-774
    • (1999) Mod Patho , vol.12 , pp. 770-774
    • Bayer-Garner, I.B.1    Hough Jr., A.J.2    Smoller, B.R.3
  • 23
    • 61549143718 scopus 로고    scopus 로고
    • Clinical impact of high-throughput gene expression studies in lung cancer
    • Beane J, Spira A, Lenburg ME (2009) Clinical impact of high-throughput gene expression studies in lung cancer. J Thorac Oncol 4:109-118
    • (2009) J Thorac Oncol , vol.4 , pp. 109-118
    • Beane, J.1    Spira, A.2    Lenburg, M.E.3
  • 24
    • 0842329639 scopus 로고    scopus 로고
    • Induction of Hsp90 protein expression in malignant melanomas and melanoma me-tastases
    • Becker B, Multhoff G, Farkas B et al. (2004) Induction of Hsp90 protein expression in malignant melanomas and melanoma me-tastases. Exp Dermatol 13:27-32
    • (2004) Exp Dermatol , vol.13 , pp. 27-32
    • Becker, B.1    Multhoff, G.2    Farkas, B.3
  • 25
    • 35348993165 scopus 로고    scopus 로고
    • Gene expression profiling of human melanoma cell lines with distinct metastatic potential identifies new progression markers
    • Bertucci F, Pages C, Finetti P et al. (2007) Gene expression profiling of human melanoma cell lines with distinct metastatic potential identifies new progression markers. Antic-ancer Res 27:3441-3449
    • (2007) Antic-ancer Res , vol.27 , pp. 3441-3449
    • Bertucci, F.1    Pages, C.2    Finetti, P.3
  • 26
    • 4744366992 scopus 로고    scopus 로고
    • CD10 protein expression in tumor and stromal cells of malignant melanoma is associated with tumor progression
    • Bilalovic N, Sandstad B, Golouh R et al. (2004) CD10 protein expression in tumor and stromal cells of malignant melanoma is associated with tumor progression. Mod Pathol 17:1251-1258
    • (2004) Mod Pathol , vol.17 , pp. 1251-1258
    • Bilalovic, N.1    Sandstad, B.2    Golouh, R.3
  • 27
    • 0032818461 scopus 로고    scopus 로고
    • Expression of basic fibroblast growth factor and vascular endothelial growth factor in primary and metastatic melanoma from the same patients
    • Birck A, Kirkin AF, Zeuthen J et al. (1999) Expression of basic fibroblast growth factor and vascular endothelial growth factor in primary and metastatic melanoma from the same patients. Melanoma Res 9:375-381
    • (1999) Melanoma Res , vol.9 , pp. 375-381
    • Birck, A.1    Kirkin, A.F.2    Zeuthen, J.3
  • 28
    • 0027325928 scopus 로고
    • An immunophenotypic survey of malignant melanomas
    • Bishop PW, Menasce LP, Yates AJ et al. (1993) An immunophenotypic survey of malignant melanomas. Histopathology 23:159-166
    • (1993) Histopathology , vol.23 , pp. 159-166
    • Bishop, P.W.1    Menasce, L.P.2    Yates, A.J.3
  • 29
    • 0034601455 scopus 로고    scopus 로고
    • Molecular classification of cutaneous malignant melanoma by gene expression profiling
    • Bittner M, Meltzer P, Chen Y et al. (2000) Molecular classification of cutaneous malignant melanoma by gene expression profiling. Nature 406:536-540
    • (2000) Nature , vol.406 , pp. 536-540
    • Bittner, M.1    Meltzer, P.2    Chen, Y.3
  • 30
    • 0035087474 scopus 로고    scopus 로고
    • Matrix metalloproteinase expression in malignant melanomas: Tumor-extracellular matrix interactions in invasion and metastasis
    • Bodey B, Bodey BJr, Siegel SE, et al. (2001) Matrix metalloproteinase expression in malignant melanomas: tumor-extracellular matrix interactions in invasion and metastasis. In Vivo15:57-64
    • (2001) Vivo , vol.15 , pp. 57-64
    • Bodey, B.1    Bodey Jr., B.2    Siegel, S.E.3
  • 31
    • 2642695720 scopus 로고    scopus 로고
    • C-myc is not useful as prognostic immuno-histochemical marker in cutaneous melanoma
    • Boni R, Bantschapp O, Muller B et al. (1998) c-myc is not useful as prognostic immuno-histochemical marker in cutaneous melanoma. Dermatology 196:288-291
    • (1998) Dermatology , vol.196 , pp. 288-291
    • Boni, R.1    Bantschapp, O.2    Muller, B.3
  • 32
    • 0031039198 scopus 로고    scopus 로고
    • Ca(2+)-binding proteins S100A6 and S100B in primary cutaneous melanoma
    • Boni R, Heizmann CW, Doguoglu A, et al. (1997) Ca(2+)-binding proteins S100A6 and S100B in primary cutaneous melanoma. J Cutan Pathol 24:76-80
    • (1997) J Cutan Pathol , vol.24 , pp. 76-80
    • Boni, R.1    Heizmann, C.W.2    Doguoglu, A.3
  • 33
    • 51749113339 scopus 로고    scopus 로고
    • The role of VEGF-C staining in predicting regional metastasis in melanoma
    • Boone B, Blokx W, De Bacquer D et al. (2008) The role of VEGF-C staining in predicting regional metastasis in melanoma. Virchows Arch 453:257-65
    • (2008) Virchows Arch , vol.453 , pp. 257-265
    • Boone, B.1    Blokx, W.2    De Bacquer, D.3
  • 34
    • 58449129853 scopus 로고    scopus 로고
    • Macrophage inhibitory cytokine-1 is over-expressed in malignant melanoma and is associated with tumorigenicity
    • Arch 453:257-65 Boyle GM, Pedley J, Martyn AC et al. (2009) Macrophage inhibitory cytokine-1 is over-expressed in malignant melanoma and is associated with tumorigenicity. J Invest Dermatol 129:383-391
    • (2009) J Invest Dermatol , vol.129 , pp. 383-391
    • Boyle, G.M.1    Pedley, J.2    Martyn, A.C.3
  • 35
    • 49949091280 scopus 로고    scopus 로고
    • The role of vascular endothelial growth factors and their receptors in malignant melanomas
    • Brychtova S, Bezdekova M, Brychta T, et al. (2008) The role of vascular endothelial growth factors and their receptors in malignant melanomas. Neoplasma 55:273-279
    • (2008) Neoplasma , vol.55 , pp. 273-279
    • Brychtova, S.1    Bezdekova, M.2    Brychta, T.3
  • 36
    • 33644838317 scopus 로고    scopus 로고
    • The role of intermedial filament nestin in malignant melanoma progression
    • Brychtova S, Fiuraskova M, Brychta T et al. (2005) [The role of intermedial filament nestin in malignant melanoma progression]. Cesk Patol 41:143-145
    • (2005) Cesk Patol , vol.41 , pp. 143-145
    • Brychtova, S.1    Fiuraskova, M.2    Brychta, T.3
  • 37
    • 34547783340 scopus 로고    scopus 로고
    • Skin cancer in individuals of African, Asian, Latin-American, and American-Indian descent: Differences in incidence, clinical presentation, and survival compared to Caucasians
    • Byrd-Miles K, Toombs EL, Peck GL (2007) Skin cancer in individuals of African, Asian, Latin-American, and American-Indian descent: differences in incidence, clinical presentation, and survival compared to Caucasians. J Drugs Dermatol 6:10-16
    • (2007) J Drugs Dermatol , vol.6 , pp. 10-16
    • Byrd-Miles, K.1    Toombs, E.L.2    Peck, G.L.3
  • 38
    • 57149117848 scopus 로고    scopus 로고
    • A decade of tissue microarrays: Progress in the discovery and validation of cancer biomar-kers
    • Camp RL, Neumeister V, Rimm DL (2008) A decade of tissue microarrays: progress in the discovery and validation of cancer biomar-kers. J Clin Oncol 26:5630-5637
    • (2008) J Clin Oncol , vol.26 , pp. 5630-5637
    • Camp, R.L.1    Neumeister, V.2    Rimm, D.L.3
  • 40
    • 34548069085 scopus 로고    scopus 로고
    • Decreased expression of retinoid receptors in melanoma: Entailment in tumorigenesis and prognosis
    • Chakravarti N, Lotan R, Diwan AH et al. (2007) Decreased expression of retinoid receptors in melanoma: entailment in tumorigenesis and prognosis. Clin Cancer Res 13:4817-4824
    • (2007) Clin Cancer Res , vol.13 , pp. 4817-4824
    • Chakravarti, N.1    Lotan, R.2    Diwan, A.H.3
  • 41
    • 33845799113 scopus 로고    scopus 로고
    • A small interfering CD147-targeting RNA inhibited the proliferation, invasiveness, and meta-static activity of malignant melanoma
    • Chen X, Lin J, Kanekura T et al. (2006) A small interfering CD147-targeting RNA inhibited the proliferation, invasiveness, and meta-static activity of malignant melanoma. Cancer Res 66:11323-11330
    • (2006) Cancer Res , vol.66 , pp. 11323-11330
    • Chen, X.1    Lin, J.2    Kanekura, T.3
  • 42
    • 59049101982 scopus 로고    scopus 로고
    • Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model
    • Chien AJ, Moore EC, Lonsdorf AS et al. (2009) Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model. Proc Natl Acad Sci USA 106:1193-1198
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 1193-1198
    • Chien, A.J.1    Moore, E.C.2    Lonsdorf, A.S.3
  • 43
    • 0025006276 scopus 로고
    • Immunohistochemical study of melanocytic nevus and malignant melanoma with monoclonal antibodies against S-100 subunits
    • Cho KH, Hashimoto K, Taniguchi Y, et al. (1990) Immunohistochemical study of melanocytic nevus and malignant melanoma with monoclonal antibodies against S-100 subunits. Cancer 66:765-771
    • (1990) Cancer , vol.66 , pp. 765-771
    • Cho, K.H.1    Hashimoto, K.2    Taniguchi, Y.3
  • 44
    • 34249093043 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2): First immunohistochemical mar-ker distinguishing early cutaneous melanomas from benign melanocytic skin tumours
    • Chwirot BW, Kuzbicki L (2007) Cyclooxygenase-2 (COX-2): first immunohistochemical mar-ker distinguishing early cutaneous melanomas from benign melanocytic skin tumours. Melanoma Res 17:139-145
    • (2007) Melanoma Res , vol.17 , pp. 139-145
    • Chwirot, B.W.1    Kuzbicki, L.2
  • 45
    • 0032860393 scopus 로고    scopus 로고
    • Intercellular adhesion molecule-1 (ICAM-1) and granulocyte-macrophage colony stimulating factor (GM-CSF) co-expression in cutaneous malignant melanoma lesions
    • Ciotti P, Pesce GP, Cafiero F et al. (1999) Intercellular adhesion molecule-1 (ICAM-1) and granulocyte-macrophage colony stimulating factor (GM-CSF) co-expression in cutaneous malignant melanoma lesions. Melanoma Res 9:253-260
    • (1999) Melanoma Res , vol.9 , pp. 253-260
    • Ciotti, P.1    Pesce, G.P.2    Cafiero, F.3
  • 46
  • 47
    • 24044496547 scopus 로고    scopus 로고
    • Loss of claudin-1 expression in tumor-associated vessels correlates with acquisition of metastatic phenotype in melanocytic neoplasms
    • Cohn ML, Goncharuk VN, Diwan AH et al. (2005) Loss of claudin-1 expression in tumor-associated vessels correlates with acquisition of metastatic phenotype in melanocytic neoplasms. J Cutan Pathol 32:533-536
    • (2005) J Cutan Pathol , vol.32 , pp. 533-536
    • Cohn, M.L.1    Goncharuk, V.N.2    Diwan, A.H.3
  • 48
    • 30844434574 scopus 로고    scopus 로고
    • Collagenase-3 (MMP-13) expression in cutaneous malignant melanoma
    • Corte MD, Gonzalez LO, Corte MG et al. (2005) Collagenase-3 (MMP-13) expression in cutaneous malignant melanoma. Int J Biol Markers 20:242-248
    • (2005) Int J Biol Markers , vol.20 , pp. 242-248
    • Corte, M.D.1    Gonzalez, L.O.2    Corte, M.G.3
  • 49
    • 0037633747 scopus 로고    scopus 로고
    • Expression of c-met tyrosine kinase receptor is biologically and prognostically relevant for primary cutaneous malignant melanomas
    • Cruz J, Reis-Filho JS, Silva P et al. (2003) Expression of c-met tyrosine kinase receptor is biologically and prognostically relevant for primary cutaneous malignant melanomas. Oncology 65:72-82
    • (2003) Oncology , vol.65 , pp. 72-82
    • Cruz, J.1    Reis-Filho, J.S.2    Silva, P.3
  • 50
    • 53249090604 scopus 로고    scopus 로고
    • WNT5A expression increases during melanoma progression and correlates with outcome
    • Da Forno PD, Pringle JH, Hutchinson P et al. (2008) WNT5A expression increases during melanoma progression and correlates with outcome. Clin Cancer Res 14:5825-5832
    • (2008) Clin Cancer Res , vol.14 , pp. 5825-5832
    • Da Forno, P.D.1    Pringle, J.H.2    Hutchinson, P.3
  • 51
    • 0141891463 scopus 로고    scopus 로고
    • Increased expression of integrin-linked kinase is correlated with melanoma progression and poor patient survival
    • Dai DL, Makretsov N, Campos EI et al. (2003) Increased expression of integrin-linked kinase is correlated with melanoma progression and poor patient survival. Clin Cancer Res 9:4409-4414
    • (2003) Clin Cancer Res , vol.9 , pp. 4409-4414
    • Dai, D.L.1    Makretsov, N.2    Campos, E.I.3
  • 52
    • 5044237664 scopus 로고    scopus 로고
    • Reduced Apaf-1 expression in human cutaneous melanomas
    • DOI 10.1038/sj.bjc.6602092
    • Dai DL, Martinka M, Bush JA et al. (2004) Reduced Apaf-1 expression in human cutaneous melanomas. Br J Cancer 91:1089-1095 (Pubitemid 39336247)
    • (2004) British Journal of Cancer , vol.91 , Issue.6 , pp. 1089-1095
    • Dai, D.L.1    Martinka, M.2    Bush, J.A.3    Li, G.4
  • 53
    • 0028990414 scopus 로고
    • Alpha v-integrins in human melanoma: Gain of alpha v beta 3 and loss of alpha v beta 5 are related to tumor progression in situ but not to metastatic capacity of cell lines in nude mice
    • Danen EH, Jansen KF, Van Kraats AA et al. (1995) Alpha v-integrins in human melanoma: gain of alpha v beta 3 and loss of alpha v beta 5 are related to tumor progression in situ but not to metastatic capacity of cell lines in nude mice. Int J Cancer 61:491-496
    • (1995) Int J Cancer , vol.61 , pp. 491-496
    • Danen, E.H.1    Jansen, K.F.2    Van Kraats, A.A.3
  • 54
    • 0028175651 scopus 로고
    • Emergence of alpha 5 beta 1 fibro-nectin- and alpha v beta 3 vitronectin-receptor expression in melanocytic tumour progression
    • Danen EH, Ten Berge PJ, Van Muijen GN et al. (1994) Emergence of alpha 5 beta 1 fibro-nectin- and alpha v beta 3 vitronectin-receptor expression in melanocytic tumour progression. Histopathology 24:249-256
    • (1994) Histopathology , vol.24 , pp. 249-256
    • Danen, E.H.1    Ten Berge, P.J.2    Van Muijen, G.N.3
  • 55
    • 58849129029 scopus 로고    scopus 로고
    • Estrogen receptor expression in cutaneous melanoma: A real-time reverse transcriptase-polymerase chain reaction and immunohis-tochemical study
    • de Giorgi V, Mavilia C, Massi D et al. (2009) Estrogen receptor expression in cutaneous melanoma: a real-time reverse transcriptase-polymerase chain reaction and immunohis-tochemical study. Arch Dermatol 145:30-36
    • (2009) Arch Dermatol , vol.145 , pp. 30-36
    • De Giorgi, V.1    Mavilia, C.2    Massi, D.3
  • 56
    • 0035159576 scopus 로고    scopus 로고
    • Expression of gp100, MART-1, tyrosinase, and S100 in paraffin-embedded primary melanomas and locoregional, lymph node, and visceral metastases: Implications for diagnosis and immunotherapy. A study conducted by the EORTC Melanoma Cooperative Group
    • de Vries TJ, Smeets M, de Graaf R et al. (2001) Expression of gp100, MART-1, tyrosinase, and S100 in paraffin-embedded primary melanomas and locoregional, lymph node, and visceral metastases: implications for diagnosis and immunotherapy. A study conducted by the EORTC Melanoma Cooperative Group. J Pathol 193:13-20
    • (2001) J Pathol , vol.193 , pp. 13-20
    • De Vries, T.J.1    Smeets, M.2    De Graaf, R.3
  • 57
    • 33645541894 scopus 로고    scopus 로고
    • The correlation of angiogen-esis with metastasis in primary cutaneous melanoma: A comparative analysis of micro-vessel density, expression of vascular en-dothelial growth factor and basic fibroblastic growth factor
    • Demirkesen C, Buyukpinarbasili N, Ramazanoglu R et al. (2006) The correlation of angiogen-esis with metastasis in primary cutaneous melanoma: a comparative analysis of micro-vessel density, expression of vascular en-dothelial growth factor and basic fibroblastic growth factor. Pathology 38:132-137
    • (2006) Pathology , vol.38 , pp. 132-137
    • Demirkesen, C.1    Buyukpinarbasili, N.2    Ramazanoglu, R.3
  • 58
    • 0035041835 scopus 로고    scopus 로고
    • Expression of the endothelin-B receptor in pigment cell lesions of the skin. Evidence for its role as tumor progression marker in malignant melanoma
    • Demunter A, De Wolf-Peeters C, Degreef H et al. (2001) Expression of the endothelin-B receptor in pigment cell lesions of the skin. Evidence for its role as tumor progression marker in malignant melanoma. Virchows Arch 438:485-491
    • (2001) Virchows Arch , vol.438 , pp. 485-491
    • Demunter, A.1    De Wolf-Peeters, C.2    Degreef, H.3
  • 59
    • 0036229264 scopus 로고    scopus 로고
    • Loss of membranous expression of beta-catenin is associated with tumor progression in cutaneous melanoma and rarely caused by exon 3 mutations
    • Demunter A, Libbrecht L, Degreef H et al. (2002) Loss of membranous expression of beta-catenin is associated with tumor progression in cutaneous melanoma and rarely caused by exon 3 mutations. Mod Pathol 15:454-461
    • (2002) Mod Pathol , vol.15 , pp. 454-461
    • Demunter, A.1    Libbrecht, L.2    Degreef, H.3
  • 60
    • 0035139062 scopus 로고    scopus 로고
    • Expression of cyclooxygenase 2 in human malignant melanoma
    • Denkert C, Kobel M, Berger S et al. (2001) Expression of cyclooxygenase 2 in human malignant melanoma. Cancer Res 61:303-308
    • (2001) Cancer Res , vol.61 , pp. 303-308
    • Denkert, C.1    Kobel, M.2    Berger, S.3
  • 61
    • 0026717214 scopus 로고
    • A study of adhesion molecules as markers of progression in malignant melanoma
    • Denton KJ, Stretch JR, Gatter KC et al. (1992) A study of adhesion molecules as markers of progression in malignant melanoma. JPathol 167:187-191
    • (1992) JPathol , vol.167 , pp. 187-191
    • Denton, K.J.1    Stretch, J.R.2    Gatter, K.C.3
  • 62
    • 40149104088 scopus 로고    scopus 로고
    • Prognosis in human melanoma: PAR-1 expression is superior to other coagulation components and VEGF
    • Depasquale I, Thompson WD (2008) Prognosis in human melanoma: PAR-1 expression is superior to other coagulation components and VEGF. Histopathology 52:500-509
    • (2008) Histopathology , vol.52 , pp. 500-509
    • Depasquale, I.1    Thompson, W.D.2
  • 63
    • 57749098673 scopus 로고    scopus 로고
    • Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation
    • Dissanayake SK, Olkhanud PB, OConnell MP et al. (2008) Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation. Cancer Res 68:10205-10214
    • (2008) Cancer Res , vol.68 , pp. 10205-10214
    • Dissanayake, S.K.1    Olkhanud, P.B.2    Oconnell, M.P.3
  • 64
    • 0347985694 scopus 로고    scopus 로고
    • Differential downregulation of endoplasmic reticulum-residing chaperones calnexin and calreticulin in human metastatic melanoma
    • Dissemond J, Busch M, Kothen T et al. (2004) Differential downregulation of endoplasmic reticulum-residing chaperones calnexin and calreticulin in human metastatic melanoma. Cancer Lett 203:225-231
    • (2004) Cancer Lett , vol.203 , pp. 225-231
    • Dissemond, J.1    Busch, M.2    Kothen, T.3
  • 65
    • 58149379295 scopus 로고    scopus 로고
    • Claudin 1 overexpression increases invasion and is associated with aggressive histological features in oral squamous cell carcinoma
    • Dos Reis PP, Bharadwaj RR, Machado J et al. (2008) Claudin 1 overexpression increases invasion and is associated with aggressive histological features in oral squamous cell carcinoma. Cancer 113:3169-3180
    • (2008) Cancer , vol.113 , pp. 3169-3180
    • Dos Reis, P.P.1    Bharadwaj, R.R.2    MacHado, J.3
  • 66
    • 38949143636 scopus 로고    scopus 로고
    • Cancer invasion and metastasis: Changing views
    • Duffy MJ, McGowan PM, Gallagher WM (2008) Cancer invasion and metastasis: changing views. J Pathol 214:283-293
    • (2008) J Pathol , vol.214 , pp. 283-293
    • Duffy, M.J.1    McGowan, P.M.2    Gallagher, W.M.3
  • 67
    • 0033595651 scopus 로고    scopus 로고
    • Up-regulation of ephrin-A1 during melanoma progression
    • Easty DJ, Hill SP, Hsu MY et al. (1999) Up-regulation of ephrin-A1 during melanoma progression. Int J Cancer 84:494-501
    • (1999) Int J Cancer , vol.84 , pp. 494-501
    • Easty, D.J.1    Hill, S.P.2    Hsu, M.Y.3
  • 68
    • 13244290150 scopus 로고    scopus 로고
    • Nestin as a diagnostic and prognostic marker: Immuno-histochemical analysis of its expression in different tumours
    • Ehrmann J, Kolar Z, Mokry J (2005) Nestin as a diagnostic and prognostic marker: immuno-histochemical analysis of its expression in different tumours. J Clin Pathol 58:222-223
    • (2005) J Clin Pathol , vol.58 , pp. 222-223
    • Ehrmann, J.1    Kolar, Z.2    Mokry, J.3
  • 69
    • 36448966728 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor in early cutaneous melanocytic lesion progression
    • Einspahr JG, Thomas TL, Saboda K et al. (2007) Expression of vascular endothelial growth factor in early cutaneous melanocytic lesion progression. Cancer 110:2519-2527
    • (2007) Cancer , vol.110 , pp. 2519-2527
    • Einspahr, J.G.1    Thomas, T.L.2    Saboda, K.3
  • 70
    • 0141576591 scopus 로고    scopus 로고
    • Negative association of melanoma differentiation-associated gene (mda-7) and inducible nitric oxide synthase (iNOS) in human melanoma: MDA-7 regulates iNOS expression in melanoma cells
    • Ekmekcioglu S, Ellerhorst JA, Mumm JB et al. (2003) Negative association of melanoma differentiation-associated gene (mda-7) and inducible nitric oxide synthase (iNOS) in human melanoma: MDA-7 regulates iNOS expression in melanoma cells. Mol Cancer Ther 2:9-17
    • (2003) Mol Cancer Ther , vol.2 , pp. 9-17
    • Ekmekcioglu, S.1    Ellerhorst, J.A.2    Mumm, J.B.3
  • 71
    • 0036246222 scopus 로고    scopus 로고
    • Overexpression of HER-2 in thick melanoma
    • Eliopoulos P, Mohammed MQ, Henry K et al. (2002) Overexpression of HER-2 in thick melanoma. Melanoma Res 12:139-145
    • (2002) Melanoma Res , vol.12 , pp. 139-145
    • Eliopoulos, P.1    Mohammed, M.Q.2    Henry, K.3
  • 72
    • 38649083722 scopus 로고    scopus 로고
    • Immunohistochemical detection of XIAP in melanoma
    • Emanuel PO, Phelps RG, Mudgil A et al. (2008) Immunohistochemical detection of XIAP in melanoma. J Cutan Pathol 35:292-297
    • (2008) J Cutan Pathol , vol.35 , pp. 292-297
    • Emanuel, P.O.1    Phelps, R.G.2    Mudgil, A.3
  • 73
    • 33646422999 scopus 로고    scopus 로고
    • CXCR4 chemokine receptor mediates prostate tumor cell adhesion through alpha5 and beta3 integrins
    • Engl T, Relja B, Marian D et al. (2006) CXCR4 chemokine receptor mediates prostate tumor cell adhesion through alpha5 and beta3 integrins. Neoplasia 8:290-301
    • (2006) Neoplasia , vol.8 , pp. 290-301
    • Engl, T.1    Relja, B.2    Marian, D.3
  • 74
    • 0030778366 scopus 로고    scopus 로고
    • Transition of horizontal to vertical growth phase melanoma is accompanied by induction of vascular endothelial growth factor expression and angiogenesis
    • Erhard H, Rietveld FJ, van Altena MC, et al. (1997) Transition of horizontal to vertical growth phase melanoma is accompanied by induction of vascular endothelial growth factor expression and angiogenesis. Melanoma Res 7(Suppl 2):S19-26
    • (1997) Melanoma Res , vol.7 , Issue.2 SUPPL.
    • Erhard, H.1    Rietveld, F.J.2    Van Altena, M.C.3
  • 75
    • 33745583838 scopus 로고    scopus 로고
    • Loss of proapoptotic Bcl-2-related multido-main proteins in primary melanomas is associated with poor prognosis
    • Fecker LF, Geilen CC, Tchernev G et al. (2006) Loss of proapoptotic Bcl-2-related multido-main proteins in primary melanomas is associated with poor prognosis. J Invest Dermatol 126:1366-1371
    • (2006) J Invest Dermatol , vol.126 , pp. 1366-1371
    • Fecker, L.F.1    Geilen, C.C.2    Tchernev, G.3
  • 76
    • 0033732424 scopus 로고    scopus 로고
    • High tPA-expression in primary melanoma of the limb correlates with good prognosis
    • Ferrier CM, Suciu S, van Geloof WL et al. (2000) High tPA-expression in primary melanoma of the limb correlates with good prognosis. Br J Cancer 83:1351-1359
    • (2000) Br J Cancer , vol.83 , pp. 1351-1359
    • Ferrier, C.M.1    Suciu, S.2    Van Geloof, W.L.3
  • 77
    • 0035149533 scopus 로고    scopus 로고
    • No evidence for c-erbB-2 overexpres-sion in cutaneous melanoma
    • Fink-Puches R, Pilarski P, Schmidbauer U et al. (2001) No evidence for c-erbB-2 overexpres-sion in cutaneous melanoma. Anticancer Res 21:2793-2795
    • (2001) Anticancer Res , vol.21 , pp. 2793-2795
    • Fink-Puches, R.1    Pilarski, P.2    Schmidbauer, U.3
  • 78
    • 27944507651 scopus 로고    scopus 로고
    • Molecular changes in PDEGF and bFGF in malignant melanomas in relation to the stromal microenvironment
    • Fiuraskova M, Brychtova S, Sedlakova E et al. (2005) Molecular changes in PDEGF and bFGF in malignant melanomas in relation to the stromal microenvironment. Anticancer Res 25:4299-4303
    • (2005) Anticancer Res , vol.25 , pp. 4299-4303
    • Fiuraskova, M.1    Brychtova, S.2    Sedlakova, E.3
  • 79
    • 4344645086 scopus 로고    scopus 로고
    • Expression of activated TrkA protein in melanocytic tumors: Relationship to cell proliferation and clinical outcome
    • Florenes VA, Maelandsmo GM, Holm R et al. (2004) Expression of activated TrkA protein in melanocytic tumors: relationship to cell proliferation and clinical outcome. Am JClin Pathol 122:412-420
    • (2004) Am JClin Pathol , vol.122 , pp. 412-420
    • Florenes, V.A.1    Maelandsmo, G.M.2    Holm, R.3
  • 80
    • 58149265464 scopus 로고    scopus 로고
    • Claudin-1 protein expression is a prognostic marker of patient survival in renal cell carcinomas
    • Fritzsche FR, Oelrich B, Johannsen M, et al. (2008) Claudin-1 protein expression is a prognostic marker of patient survival in renal cell carcinomas. Clin Cancer Res 14:7035-7042
    • (2008) Clin Cancer Res , vol.14 , pp. 7035-7042
    • Fritzsche, F.R.1    Oelrich, B.2    Johannsen, M.3
  • 81
    • 0142120661 scopus 로고    scopus 로고
    • Hypoxia-inducible factors 1alpha and 2alpha are related to vascular endothelial growth factor expression and a poorer prognosis in nodular malignant melanomas of the skin
    • Giatromanolaki A, Sivridis E, Kouskoukis C et al. (2003) Hypoxia-inducible factors 1alpha and 2alpha are related to vascular endothelial growth factor expression and a poorer prognosis in nodular malignant melanomas of the skin. Melanoma Res 13:493-501
    • (2003) Melanoma Res , vol.13 , pp. 493-501
    • Giatromanolaki, A.1    Sivridis, E.2    Kouskoukis, C.3
  • 82
    • 33846046456 scopus 로고    scopus 로고
    • Protein expression of melanocyte growth factors (bFGF, SCF) and their receptors (FGFR-1, c-kit) in nevi and melanoma
    • Giehl KA, Nagele U, Volkenandt M et al. (2007) Protein expression of melanocyte growth factors (bFGF, SCF) and their receptors (FGFR-1, c-kit) in nevi and melanoma. J Cutan Pathol 34:7-14
    • (2007) J Cutan Pathol , vol.34 , pp. 7-14
    • Giehl, K.A.1    Nagele, U.2    Volkenandt, M.3
  • 84
    • 30744458937 scopus 로고    scopus 로고
    • A population-based validation of the American Joint Committee on Cancer melanoma staging system
    • Gimotty PA, Botbyl J, Soong SJ et al. (2005) A population-based validation of the American Joint Committee on Cancer melanoma staging system. J Clin Oncol 23:8065-8075
    • (2005) J Clin Oncol , vol.23 , pp. 8065-8075
    • Gimotty, P.A.1    Botbyl, J.2    Soong, S.J.3
  • 85
    • 34047232748 scopus 로고    scopus 로고
    • Identification of high-risk patients among those diagnosed with thin cutaneous melanomas
    • Gimotty PA, Elder DE, Fraker DL et al. (2007) Identification of high-risk patients among those diagnosed with thin cutaneous melanomas. J Clin Oncol 25:1129-1134
    • (2007) J Clin Oncol , vol.25 , pp. 1129-1134
    • Gimotty, P.A.1    Elder, D.E.2    Fraker, D.L.3
  • 86
    • 63649143625 scopus 로고    scopus 로고
    • Tissue biomarkers for prognosis in cutaneous melanoma: A systematic review and meta-analysis
    • Gould Rothberg BE, Bracken MB, Rimm DL (2009) Tissue biomarkers for prognosis in cutaneous melanoma: a systematic review and meta-analysis. J Natl Cancer Inst 101:452-474
    • (2009) J Natl Cancer Inst , vol.101 , pp. 452-474
    • Gould Rothberg, B.E.1    Bracken, M.B.2    Rimm, D.L.3
  • 87
    • 3142587657 scopus 로고    scopus 로고
    • Analysis of cyclooxygenase 2 (COX-2) expression during malignant melanoma prgression
    • Goulet AC, Einsphar JG, Alberts DS et al. (2003) Analysis of cyclooxygenase 2 (COX-2) expression during malignant melanoma prgression. Cancer Biol Ther 2:713-718
    • (2003) Cancer Biol Ther , vol.2 , pp. 713-718
    • Goulet, A.C.1    Einsphar, J.G.2    Alberts, D.S.3
  • 88
    • 41849102400 scopus 로고    scopus 로고
    • Raf kinase inhibitory protein: A signal transduction modulator and metastasis suppressor
    • Granovsky AE, Rosner MR (2008) Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor. Cell Res 18:452-457
    • (2008) Cell Res , vol.18 , pp. 452-457
    • Granovsky, A.E.1    Rosner, M.R.2
  • 89
    • 34250174504 scopus 로고    scopus 로고
    • The role of epithelial-mesenchymal transition in cancer pathology
    • Guarino M, Rubino B, Ballabio G (2007) The role of epithelial-mesenchymal transition in cancer pathology. Pathology 39:305-318
    • (2007) Pathology , vol.39 , pp. 305-318
    • Guarino, M.1    Rubino, B.2    Ballabio, G.3
  • 90
    • 0036871128 scopus 로고    scopus 로고
    • The role of interleukin-8 in the initiation and progression of human cutaneous melanoma
    • Gutman M, Even-Sapir E, Merimsky O et al. (2002) The role of interleukin-8 in the initiation and progression of human cutaneous melanoma. Anticancer Res 22:3395-3398
    • (2002) Anticancer Res , vol.22 , pp. 3395-3398
    • Gutman, M.1    Even-Sapir, E.2    Merimsky, O.3
  • 91
    • 1542356388 scopus 로고    scopus 로고
    • Loss of EphB6 expression in metastatic melanoma
    • Hafner C, Bataille F, Meyer S et al. (2003) Loss of EphB6 expression in metastatic melanoma. IntJ Oncol 23:1553-1559
    • (2003) IntJ Oncol , vol.23 , pp. 1553-1559
    • Hafner, C.1    Bataille, F.2    Meyer, S.3
  • 92
    • 0022550880 scopus 로고
    • Correlation of histopathological characteristics with staining patterns in human melanoma assessed by (monoclonal) anti-bodies reactive on paraffin sections
    • Hagen EC, Vennegoor C, Schlingemann RO et al. (1986) Correlation of histopathological characteristics with staining patterns in human melanoma assessed by (monoclonal) anti-bodies reactive on paraffin sections. Histo- pathology 10:689-700
    • (1986) Histo- Pathology , vol.10 , pp. 689-700
    • Hagen, E.C.1    Vennegoor, C.2    Schlingemann, R.O.3
  • 93
    • 73449093121 scopus 로고    scopus 로고
    • CD147 expression indicates unfavourable prognosis in prostate cancer
    • Han ZD, Bi XC, Qin WJ et al. (2008a) CD147 expression indicates unfavourable prognosis in prostate cancer. Pathol Oncol Res 2:2
    • (2008) Pathol Oncol Res , vol.2 , pp. 2
    • Han, Z.D.1    Bi, X.C.2    Qin, W.J.3
  • 94
    • 75149142882 scopus 로고    scopus 로고
    • Expression and clinical significance of CD147 in genitourinary carcinomas
    • Han ZD, He HC, Bi XC et al. (2008b) Expression and clinical significance of CD147 in genitourinary carcinomas. J Surg Res 10:10
    • (2008) J Surg Res , vol.10 , pp. 10
    • Han, Z.D.1    He, H.C.2    Bi, X.C.3
  • 95
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100:57-70
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 96
    • 0037542604 scopus 로고    scopus 로고
    • ICAM-1 and beta(3)integrin immu-noexpression in malignant melanoma cells: Can they be used as additional predictors?
    • Haritopoulos KN, Lazaris AC, Kavantzas N et al. (2003) ICAM-1 and beta(3) integrin immu-noexpression in malignant melanoma cells: can they be used as additional predictors? APMIS 111:421-429
    • (2003) APMIS , vol.111 , pp. 421-429
    • Haritopoulos, K.N.1    Lazaris, A.C.2    Kavantzas, N.3
  • 97
    • 5644300960 scopus 로고    scopus 로고
    • Up-regulation of Flotillin-2 is associated with melanoma progression and modulates expression of the thrombin receptor protease activated receptor 1
    • Hazarika P, McCarty MF, Prieto VG et al. (2004) Up-regulation of Flotillin-2 is associated with melanoma progression and modulates expression of the thrombin receptor protease activated receptor 1. Cancer Res 64:7361-7369
    • (2004) Cancer Res , vol.64 , pp. 7361-7369
    • Hazarika, P.1    McCarty, M.F.2    Prieto, V.G.3
  • 98
    • 0031735790 scopus 로고    scopus 로고
    • In vivo human melanoma cytokine production: Inverse correlation of GM-CSF production with tumor depth
    • Hensley C, Spitzler S, McAlpine BE et al. (1998) In vivo human melanoma cytokine production: inverse correlation of GM-CSF production with tumor depth. Exp Dermatol 7:335-341
    • (1998) Exp Dermatol , vol.7 , pp. 335-341
    • Hensley, C.1    Spitzler, S.2    McAlpine, B.E.3
  • 99
    • 27544479450 scopus 로고    scopus 로고
    • Focal adhesion kinase promotes the aggressive melanoma phenotype
    • Hess AR, Postovit LM, Margaryan NV, et al. (2005) Focal adhesion kinase promotes the aggressive melanoma phenotype. Cancer Res 65:9851-9860
    • (2005) Cancer Res , vol.65 , pp. 9851-9860
    • Hess, A.R.1    Postovit, L.M.2    Margaryan, N.V.3
  • 100
    • 0029665802 scopus 로고    scopus 로고
    • Beta3 integrin expression in melanoma predicts subsequent metastasis
    • Hieken TJ, Farolan M, Ronan SG et al. (1996) Beta3 integrin expression in melanoma predicts subsequent metastasis. J Surg Res 63:169-173
    • (1996) J Surg Res , vol.63 , pp. 169-173
    • Hieken, T.J.1    Farolan, M.2    Ronan, S.G.3
  • 101
    • 0032916904 scopus 로고    scopus 로고
    • Molecular prognostic markers in intermediate-thickness cutaneous malignant melanoma
    • Hieken TJ, Ronan SG, Farolan M et al. (1999) Molecular prognostic markers in intermediate-thickness cutaneous malignant melanoma. Cancer 85:375-382
    • (1999) Cancer , vol.85 , pp. 375-382
    • Hieken, T.J.1    Ronan, S.G.2    Farolan, M.3
  • 102
    • 0033923006 scopus 로고    scopus 로고
    • Expression and activation of matrix metalloproteinase-2 (MMP-2) and its co-localization with membrane-type 1 matrix metalloproteinase (MT1-MMP) correlate with melanoma progression
    • Hofmann UB, Westphal JR, Zendman AJ et al. (2000) Expression and activation of matrix metalloproteinase-2 (MMP-2) and its co-localization with membrane-type 1 matrix metalloproteinase (MT1-MMP) correlate with melanoma progression. J Pathol 191:245-256
    • (2000) J Pathol , vol.191 , pp. 245-256
    • Hofmann, U.B.1    Westphal, J.R.2    Zendman, A.J.3
  • 103
    • 57149103930 scopus 로고    scopus 로고
    • Molecular basis for the critical role of suppressor of cytokine signaling-1 in melanoma brain metastasis
    • Huang FJ, Steeg PS, Price JE et al. (2008) Molecular basis for the critical role of suppressor of cytokine signaling-1 in melanoma brain metastasis. Cancer Res 68:9634-9642
    • (2008) Cancer Res , vol.68 , pp. 9634-9642
    • Huang, F.J.1    Steeg, P.S.2    Price, J.E.3
  • 104
    • 0034909244 scopus 로고    scopus 로고
    • Alterations of mismatch repair protein expression in benign melanocytic nevi, melanocytic dysplastic nevi, and cutaneous malignant melanomas
    • Hussein MR, Roggero E, Sudilovsky EC et al. (2001) Alterations of mismatch repair protein expression in benign melanocytic nevi, melanocytic dysplastic nevi, and cutaneous malignant melanomas. Am J Dermatopathol 23:308-314
    • (2001) Am J Dermatopathol , vol.23 , pp. 308-314
    • Hussein, M.R.1    Roggero, E.2    Sudilovsky, E.C.3
  • 106
    • 0037258555 scopus 로고    scopus 로고
    • Fatty acid synthase expression in melanoma
    • Innocenzi D, Alo PL, Balzani A, et al. (2003) Fatty acid synthase expression in melanoma. J Cutan Pathol 30:23-28
    • (2003) J Cutan Pathol , vol.30 , pp. 23-28
    • Innocenzi, D.1    Alo, P.L.2    Balzani, A.3
  • 107
    • 0035037568 scopus 로고    scopus 로고
    • Expression of neurotrophins and their receptors in pigment cell lesions of the skin
    • Innominato PF, Libbrecht L, van den Oord JJ (2001) Expression of neurotrophins and their receptors in pigment cell lesions of the skin. J Pathol 194:95-100
    • (2001) J Pathol , vol.194 , pp. 95-100
    • Innominato, P.F.1    Libbrecht, L.2    Van Den Oord, J.J.3
  • 109
    • 63449131596 scopus 로고    scopus 로고
    • Matrix metalloprotei-nase-2 involvement in breast cancer progression: A mini-review
    • Jezierska A, Motyl T (2009) Matrix metalloprotei-nase-2 involvement in breast cancer progression: a mini-review. Med Sci Monit 15:RA32-40
    • (2009) Med Sci Monit , vol.15
    • Jezierska, A.1    Motyl, T.2
  • 110
    • 0000687105 scopus 로고
    • De novo expression of intercellular-adhesion molecule 1 in melanoma correlates with increased risk of metastasis
    • Johnson JP, Stade BG, Holzmann B et al. (1989) De novo expression of intercellular-adhesion molecule 1 in melanoma correlates with increased risk of metastasis. Proc Natl Acad Sci USA 86:641-644
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 641-644
    • Johnson, J.P.1    Stade, B.G.2    Holzmann, B.3
  • 111
    • 33750377724 scopus 로고    scopus 로고
    • Activation of c-jun N-terminal kinase is associated with cell proliferation and shorter relapse-free period in superficial spreading malignant melanoma
    • Jorgensen K, Davidson B, Florenes VA (2006) Activation of c-jun N-terminal kinase is associated with cell proliferation and shorter relapse-free period in superficial spreading malignant melanoma. Mod Pathol 19:1446-1455
    • (2006) Mod Pathol , vol.19 , pp. 1446-1455
    • Jorgensen, K.1    Davidson, B.2    Florenes, V.A.3
  • 112
    • 0242441992 scopus 로고    scopus 로고
    • Expression of activated extracellular signal-regulated kinases 1/2 in malignant melanomas: Relationship with clinical outcome
    • Jorgensen K, Holm R, Maelandsmo GM et al. (2003) Expression of activated extracellular signal-regulated kinases 1/2 in malignant melanomas: relationship with clinical outcome. Clin Cancer Res 9:5325-5331
    • (2003) Clin Cancer Res , vol.9 , pp. 5325-5331
    • Jorgensen, K.1    Holm, R.2    Maelandsmo, G.M.3
  • 113
    • 77954760145 scopus 로고    scopus 로고
    • A molecular signature for epithelial to me-senchymal transition in a human colon cancer cell system is revealed by large-scale microarray analysis
    • Joyce T, Cantarella D, Isella C et al. (2009) A molecular signature for epithelial to me-senchymal transition in a human colon cancer cell system is revealed by large-scale microarray analysis. Clin Exp Metastasis 2:2
    • (2009) Clin Exp Metastasis , vol.2 , pp. 2
    • Joyce, T.1    Cantarella, D.2    Isella, C.3
  • 114
    • 33750739534 scopus 로고    scopus 로고
    • HSP-70, C-myc and HLA-DR expression in patients with cutaneous malignant melanoma metastatic in lymph nodes
    • Kalogeraki A, Garbagnati F, Darivianaki K et al. (2006) HSP-70, C-myc and HLA-DR expression in patients with cutaneous malignant melanoma metastatic in lymph nodes. Antic-ancer Res 26:3551-3554
    • (2006) Antic-ancer Res , vol.26 , pp. 3551-3554
    • Kalogeraki, A.1    Garbagnati, F.2    Darivianaki, K.3
  • 115
    • 0035999094 scopus 로고    scopus 로고
    • Differential expression of the CD10 antigen (neutral endopeptidase) in primary versus metastatic malignant melanomas of the skin
    • Kanitakis J, Narvaez D, Claudy A (2002) Differential expression of the CD10 antigen (neutral endopeptidase) in primary versus metastatic malignant melanomas of the skin. Melanoma Res 12:241-244
    • (2002) Melanoma Res , vol.12 , pp. 241-244
    • Kanitakis, J.1    Narvaez, D.2    Claudy, A.3
  • 116
    • 13944263967 scopus 로고    scopus 로고
    • PUMA expression is significantly reduced in human cutaneous melanomas
    • Karst AM, Dai DL, Martinka M et al. (2005) PUMA expression is significantly reduced in human cutaneous melanomas. Oncogene 24:1111-1116
    • (2005) Oncogene , vol.24 , pp. 1111-1116
    • Karst, A.M.1    Dai, D.L.2    Martinka, M.3
  • 117
    • 0037455843 scopus 로고    scopus 로고
    • Tissue microarray-based analysis shows phospho-beta-catenin expression in malignant melanoma is associated with poor outcome
    • Kielhorn E, Provost E, Olsen D et al. (2003) Tissue microarray-based analysis shows phospho-beta-catenin expression in malignant melanoma is associated with poor outcome. Int J Cancer 103:652-656
    • (2003) Int J Cancer , vol.103 , pp. 652-656
    • Kielhorn, E.1    Provost, E.2    Olsen, D.3
  • 118
    • 0037069935 scopus 로고    scopus 로고
    • Neoplastic progression in melanoma and colon cancer is associated with increased expression and activity of the interferon-inducible protein kinase, PKR
    • Kim SH, Gunnery S, Choe JK et al. (2002) Neoplastic progression in melanoma and colon cancer is associated with increased expression and activity of the interferon-inducible protein kinase, PKR. Oncogene 21:8741-8748
    • (2002) Oncogene , vol.21 , pp. 8741-8748
    • Kim, S.H.1    Gunnery, S.2    Choe, J.K.3
  • 119
    • 33845702260 scopus 로고    scopus 로고
    • Increased expression of stem cell markers in malignant melanoma
    • Klein WM, Wu BP, Zhao S, et al. (2007) Increased expression of stem cell markers in malignant melanoma. Mod Pathol 20:102-107
    • (2007) Mod Pathol , vol.20 , pp. 102-107
    • Klein, W.M.1    Wu, B.P.2    Zhao, S.3
  • 120
    • 3042797636 scopus 로고    scopus 로고
    • Her2/neu is not a commonly expressed therapeutic target in melanoma-a large cohort tissue microarray study
    • Kluger HM, DiVito K, Berger AJ et al. (2004) Her2/neu is not a commonly expressed therapeutic target in melanoma-a large cohort tissue microarray study. Melanoma Res 14:207-210
    • (2004) Melanoma Res , vol.14 , pp. 207-210
    • Kluger, H.M.1    Divito, K.2    Berger, A.J.3
  • 121
    • 0031822837 scopus 로고    scopus 로고
    • Tissue microarrays for high-throughput molecular profiling of tumor specimens
    • Kononen J, Bubendorf L, Kallioniemi A et al. (1998) Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat Med 4:844-847
    • (1998) Nat Med , vol.4 , pp. 844-847
    • Kononen, J.1    Bubendorf, L.2    Kallioniemi, A.3
  • 122
    • 0029556025 scopus 로고
    • Antigen Ki-67 and c-myc oncogene as related to histoclinical parameters in pig-mented skin lesions
    • Korabiowska M, Brinck U, Mirecka J et al. (1995) Antigen Ki-67 and c-myc oncogene as related to histoclinical parameters in pig-mented skin lesions. In Vivo 9:433-438
    • (1995) Vivo , vol.9 , pp. 433-438
    • Korabiowska, M.1    Brinck, U.2    Mirecka, J.3
  • 123
    • 10344225048 scopus 로고    scopus 로고
    • Analysis of adenomatous polyposis coli gene expression, APC locus-microsatellite in-stability and APC promoter methylation in the progression of melanocytic tumours
    • Korabiowska M, Schlott T, Siems N et al. (2004) Analysis of adenomatous polyposis coli gene expression, APC locus-microsatellite in-stability and APC promoter methylation in the progression of melanocytic tumours. Mod Pathol 17:1539-1544
    • (2004) Mod Pathol , vol.17 , pp. 1539-1544
    • Korabiowska, M.1    Schlott, T.2    Siems, N.3
  • 124
    • 42149194973 scopus 로고    scopus 로고
    • Prognostic significance of cadherin-based adhesion molecules in cutaneous malignant melanoma
    • Kreizenbeck GM, Berger AJ, Subtil A et al. (2008) Prognostic significance of cadherin-based adhesion molecules in cutaneous malignant melanoma. Cancer Epidemiol Biomarkers Prev 17:949-958
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 949-958
    • Kreizenbeck, G.M.1    Berger, A.J.2    Subtil, A.3
  • 125
    • 1642440127 scopus 로고    scopus 로고
    • Cadherin expression pattern in melanocytic tumors more likely depends on the melano-cyte environment than on tumor cell prgression
    • Krengel S, Groteluschen F, Bartsch S et al. (2004) Cadherin expression pattern in melanocytic tumors more likely depends on the melano-cyte environment than on tumor cell prgression. J Cutan Pathol 31:1-7
    • (2004) J Cutan Pathol , vol.31 , pp. 1-7
    • Krengel, S.1    Groteluschen, F.2    Bartsch, S.3
  • 126
    • 28344447023 scopus 로고    scopus 로고
    • MMP-21 is upregulated at early stages of melanoma progression but disappears with more aggressive phenotype
    • Kuivanen T, Ahokas K, Virolainen S et al. (2005) MMP-21 is upregulated at early stages of melanoma progression but disappears with more aggressive phenotype. Virchows Arch 447:954-960
    • (2005) Virchows Arch , vol.447 , pp. 954-960
    • Kuivanen, T.1    Ahokas, K.2    Virolainen, S.3
  • 127
    • 33747348443 scopus 로고    scopus 로고
    • Expression of Dickkopf genes is strongly reduced in malignant melanoma
    • Kuphal S, Lodermeyer S, Bataille F et al. (2006a) Expression of Dickkopf genes is strongly reduced in malignant melanoma. Oncogene 25:5027-5036
    • (2006) Oncogene , vol.25 , pp. 5027-5036
    • Kuphal, S.1    Lodermeyer, S.2    Bataille, F.3
  • 129
    • 0036262509 scopus 로고    scopus 로고
    • Identification of activated matrix metalloproteinase-2 (MMP-2) as the main gelatinolytic enzyme in malignant melanoma by in situ zymography
    • Kurschat P, Wickenhauser C, Groth W et al. (2002) Identification of activated matrix metalloproteinase-2 (MMP-2) as the main gelatinolytic enzyme in malignant melanoma by in situ zymography. J Pathol 197:179-187
    • (2002) J Pathol , vol.197 , pp. 179-187
    • Kurschat, P.1    Wickenhauser, C.2    Groth, W.3
  • 130
    • 33746142789 scopus 로고    scopus 로고
    • Different expression of lysosome-associated membrane protein-1 in human melanomas and benign melanocytic lesions
    • DOI 10.1097/01.cmr.0000215034.00318.7a, PII 0000839020060600000005
    • Kuzbicki L, Gajo B, Chwirot BW (2006a) Different expression of lysosome-associated membrane protein-1 in human melanomas and benign melanocytic lesions. Melanoma Res 16:235-243 (Pubitemid 44085097)
    • (2006) Melanoma Research , vol.16 , Issue.3 , pp. 235-243
    • Kuzbicki, L.1    Gajo, B.2    Chwirot, B.W.3
  • 131
    • 33645456543 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 in benign naevi and during human cutaneous melanoma progression
    • Kuzbicki L, Sarnecka A, Chwirot BW (2006b) Expression of cyclooxygenase-2 in benign naevi and during human cutaneous melanoma progression. Melanoma Res16:29-36
    • (2006) Melanoma Res , vol.16 , pp. 29-36
    • Kuzbicki, L.1    Sarnecka, A.2    Chwirot, B.W.3
  • 132
    • 21444458625 scopus 로고    scopus 로고
    • Endothelin receptor B is required for the expansion of melanocyte precursors and malignant melanoma
    • Lahav R (2005) Endothelin receptor B is required for the expansion of melanocyte precursors and malignant melanoma. Int J Dev Biol 49:173-180
    • (2005) Int J Dev Biol , vol.49 , pp. 173-180
    • Lahav, R.1
  • 133
    • 10844224604 scopus 로고    scopus 로고
    • Endothelin receptor B inhibition triggers apoptosis and enhances angiogenesis in melanomas
    • Lahav R, Suva ML, Rimoldi D et al. (2004) Endothelin receptor B inhibition triggers apoptosis and enhances angiogenesis in melanomas. Cancer Res 64:8945-8953
    • (2004) Cancer Res , vol.64 , pp. 8945-8953
    • Lahav, R.1    Suva, M.L.2    Rimoldi, D.3
  • 134
    • 53749091557 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 and peroxi-some proliferator-activated receptor gamma during malignant melanoma progression
    • Lee C, Ramirez JA, Guitart J et al. (2008a) Expression of cyclooxygenase-2 and peroxi-some proliferator-activated receptor gamma during malignant melanoma progression. J Cutan Pathol 35:989-994
    • (2008) J Cutan Pathol , vol.35 , pp. 989-994
    • Lee, C.1    Ramirez, J.A.2    Guitart, J.3
  • 136
    • 62649084181 scopus 로고    scopus 로고
    • Activation of the FGF2/FGFR1 autocrine loop for cell proliferation and survival in uveal melanoma cells
    • Lefevre G, Babchia N, Calipel A et al. (2009) Activation of the FGF2/FGFR1 autocrine loop for cell proliferation and survival in uveal melanoma cells. Invest Ophthalmol Vis Sci 50:1047-1057
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 1047-1057
    • Lefevre, G.1    Babchia, N.2    Calipel, A.3
  • 137
    • 34249989451 scopus 로고    scopus 로고
    • Claudin-1 overexpression in melanoma is regulated by PKC and contributes to melanoma cell motility
    • Leotlela PD, Wade MS, Duray PH et al. (2007) Claudin-1 overexpression in melanoma is regulated by PKC and contributes to melanoma cell motility. Oncogene 26:3846-3856
    • (2007) Oncogene , vol.26 , pp. 3846-3856
    • Leotlela, P.D.1    Wade, M.S.2    Duray, P.H.3
  • 138
    • 49349105425 scopus 로고    scopus 로고
    • Role of ING4 in human melanoma cell migration, invasion and patient survival
    • Li J, Martinka M, Li G (2008) Role of ING4 in human melanoma cell migration, invasion and patient survival. Carcinogenesis 29:1373-1379
    • (2008) Carcinogenesis , vol.29 , pp. 1373-1379
    • Li, J.1    Martinka, M.2    Li, G.3
  • 139
    • 4644278484 scopus 로고    scopus 로고
    • Expression of SOCS-1, suppressor of cytokine signalling-1, in human melanoma
    • Li Z, Metze D, Nashan D et al. (2004) Expression of SOCS-1, suppressor of cytokine signalling-1, in human melanoma. J Invest Dermatol 123:737-745
    • (2004) J Invest Dermatol , vol.123 , pp. 737-745
    • Li, Z.1    Metze, D.2    Nashan, D.3
  • 140
    • 0032822208 scopus 로고    scopus 로고
    • Interferon regulatory factor-1 and -2 expression in human melanoma specimens
    • Lowney JK, Boucher LD, Swanson PE et al. (1999) Interferon regulatory factor-1 and -2 expression in human melanoma specimens. Ann Surg Oncol 6:604-608
    • (1999) Ann Surg Oncol , vol.6 , pp. 604-608
    • Lowney, J.K.1    Boucher, L.D.2    Swanson, P.E.3
  • 141
    • 0042835743 scopus 로고    scopus 로고
    • Reduced beta-catenin expression in the cytoplasm of advanced-stage superficial spreading malignant melanoma
    • Maelandsmo GM, Holm R, Nesland JM et al. (2003) Reduced beta-catenin expression in the cytoplasm of advanced-stage superficial spreading malignant melanoma. Clin Cancer Res 9:3383-3388
    • (2003) Clin Cancer Res , vol.9 , pp. 3383-3388
    • Maelandsmo, G.M.1    Holm, R.2    Nesland, J.M.3
  • 142
    • 0031002117 scopus 로고    scopus 로고
    • Angiogenesis and malignant melanoma. An-giogenesis is related to the development of vertical (tumorigenic) growth phase
    • Marcoval J, Moreno A, Graells J et al. (1997) Angiogenesis and malignant melanoma. An-giogenesis is related to the development of vertical (tumorigenic) growth phase. J Cutan Pathol 24:212-218
    • (1997) J Cutan Pathol , vol.24 , pp. 212-218
    • Marcoval, J.1    Moreno, A.2    Graells, J.3
  • 143
    • 21544440159 scopus 로고    scopus 로고
    • Expression of protease-activated receptors 1 and 2 in melanocytic nevi and malignant melanoma
    • Massi D, Naldini A, Ardinghi C et al. (2005) Expression of protease-activated receptors 1 and 2 in melanocytic nevi and malignant melanoma. Hum Pathol 36:676-685
    • (2005) Hum Pathol , vol.36 , pp. 676-685
    • Massi, D.1    Naldini, A.2    Ardinghi, C.3
  • 144
    • 40149102363 scopus 로고    scopus 로고
    • HSP90 as a marker of progression in melanoma
    • McCarthy MM, Pick E, Kluger Y et al. (2008) HSP90 as a marker of progression in melanoma. Ann Oncol 19:590-594
    • (2008) Ann Oncol , vol.19 , pp. 590-594
    • McCarthy, M.M.1    Pick, E.2    Kluger, Y.3
  • 145
    • 47749087950 scopus 로고    scopus 로고
    • Integrin-linked kinase-essential roles in physiology and cancer biology
    • McDonald PC, Fielding AB, Dedhar S (2008) Integrin-linked kinase-essential roles in physiology and cancer biology. J Cell Sci 121:3121-32
    • (2008) J Cell Sci , vol.121 , pp. 3121-3132
    • McDonald, P.C.1    Fielding, A.B.2    Dedhar, S.3
  • 146
    • 34447335892 scopus 로고    scopus 로고
    • Expression of polycomb group protein EZH2 in nevi and melanoma
    • McHugh JB, Fullen DR, Ma L et al. (2007) Expression of polycomb group protein EZH2 in nevi and melanoma. JCutan Pathol 34:597-600
    • (2007) J Cutan Pathol , vol.34 , pp. 597-600
    • McHugh, J.B.1    Fullen, D.R.2    Ma, L.3
  • 148
    • 0029436845 scopus 로고
    • Comparative distribution of S-100 protein and antigen HMB-45 in various types of melanomas and naevi
    • Mirecka J, Korabiowska M, Schauer A (1995) Comparative distribution of S-100 protein and antigen HMB-45 in various types of melanomas and naevi. Pol J Pathol 46:167-172
    • (1995) Pol J Pathol , vol.46 , pp. 167-172
    • Mirecka, J.1    Korabiowska, M.2    Schauer, A.3
  • 149
    • 34247633513 scopus 로고    scopus 로고
    • Reduced pSmad2 immunodetection correlates with increased primary melanoma thickness
    • Mnich CD, Hoek KS, Oberholzer PA, et al. (2007) Reduced pSmad2 immunodetection correlates with increased primary melanoma thickness. Melanoma Res 17:131-136
    • (2007) Melanoma Res , vol.17 , pp. 131-136
    • Mnich, C.D.1    Hoek, K.S.2    Oberholzer, P.A.3
  • 150
    • 34250817446 scopus 로고    scopus 로고
    • CXCR3 chemokine receptor immunoreactiv-ity in primary cutaneous malignant melanoma: Correlation with clinicopathologic prognostic factors
    • Monteagudo C, Martin JM, Jorda E et al. (2007) CXCR3 chemokine receptor immunoreactiv-ity in primary cutaneous malignant melanoma: correlation with clinicopathologic prognostic factors. J Clin Pathol 60:596-599
    • (2007) J Clin Pathol , vol.60 , pp. 596-599
    • Monteagudo, C.1    Martin, J.M.2    Jorda, E.3
  • 151
    • 0030823299 scopus 로고    scopus 로고
    • In situ expression of transforming growth factor beta is associated with melanoma progression and correlates with Ki67, HLA-DR and beta 3 integrin expression
    • Moretti S, Pinzi C, Berti E et al. (1997) In situ expression of transforming growth factor beta is associated with melanoma progression and correlates with Ki67, HLA-DR and beta 3 integrin expression. Melanoma Res 7:313-321
    • (1997) Melanoma Res , vol.7 , pp. 313-321
    • Moretti, S.1    Pinzi, C.2    Berti, E.3
  • 152
    • 0033046920 scopus 로고    scopus 로고
    • Immunohistochemical evidence of cytokine networks during progression of human mel-anocytic lesions
    • Moretti S, Pinzi C, Spallanzani A et al. (1999) Immunohistochemical evidence of cytokine networks during progression of human mel-anocytic lesions. Int J Cancer 84:160-168
    • (1999) Int J Cancer , vol.84 , pp. 160-168
    • Moretti, S.1    Pinzi, C.2    Spallanzani, A.3
  • 153
    • 65049090261 scopus 로고    scopus 로고
    • Tumoural expression and circulating level of VEGFR-3 (Flt-4) in metastatic melanoma patients: Correlation with clinical parameters and outcome
    • Mouawad R, Spano JP, Comperat E et al. (2009) Tumoural expression and circulating level of VEGFR-3 (Flt-4) in metastatic melanoma patients: correlation with clinical parameters and outcome. Eur J Cancer 45:1407-1414
    • (2009) Eur J Cancer , vol.45 , pp. 1407-1414
    • Mouawad, R.1    Spano, J.P.2    Comperat, E.3
  • 154
    • 22344441964 scopus 로고    scopus 로고
    • Selective heparanase localization in malignant melanoma
    • Murry BP, Greiter-Wilke A, Paulsen DP et al. (2005) Selective heparanase localization in malignant melanoma. Int JOncol 26:345-352
    • (2005) Int JOncol , vol.26 , pp. 345-352
    • Murry, B.P.1    Greiter-Wilke, A.2    Paulsen, D.P.3
  • 155
    • 33745075529 scopus 로고    scopus 로고
    • Emmprin (basigin/CD147): Matrix metallo-proteinase modulator and multifunctional cell recognition molecule that plays a critical role in cancer progression
    • Nabeshima K, Iwasaki H, Koga K et al. (2006) Emmprin (basigin/CD147): matrix metallo-proteinase modulator and multifunctional cell recognition molecule that plays a critical role in cancer progression. Pathol Int 56:359-367
    • (2006) Pathol Int , vol.56 , pp. 359-367
    • Nabeshima, K.1    Iwasaki, H.2    Koga, K.3
  • 156
    • 0025022477 scopus 로고
    • Differential expression of intercellular adhesion molecule 1 in primary and metastatic melanoma lesions
    • Natali P, Nicotra MR, Cavaliere R et al. (1990) Differential expression of intercellular adhesion molecule 1 in primary and metastatic melanoma lesions. Cancer Res 50:1271-1278
    • (1990) Cancer Res , vol.50 , pp. 1271-1278
    • Natali, P.1    Nicotra, M.R.2    Cavaliere, R.3
  • 157
    • 0030960689 scopus 로고    scopus 로고
    • Clinical significance of alpha(v)-beta3 integrin and intercellular adhesion molecule-1 expression in cutaneous malignant melanoma lesions
    • Natali PG, Hamby CV, Felding-Habermann B et al. (1997) Clinical significance of alpha(v)-beta3 integrin and intercellular adhesion molecule-1 expression in cutaneous malignant melanoma lesions. Cancer Res 57:1554-1560
    • (1997) Cancer Res , vol.57 , pp. 1554-1560
    • Natali, P.G.1    Hamby, C.V.2    Felding-Habermann, B.3
  • 158
    • 0025866127 scopus 로고
    • Tumor progression in human malignant melanoma is associated with changes in alpha 6/beta 1 laminin receptor
    • Natali PG, Nicotra MR, Cavaliere R et al. (1991) Tumor progression in human malignant melanoma is associated with changes in alpha 6/beta 1 laminin receptor. Int JCancer 49:168-172
    • (1991) Int J Cancer , vol.49 , pp. 168-172
    • Natali, P.G.1    Nicotra, M.R.2    Cavaliere, R.3
  • 159
    • 0029000256 scopus 로고
    • Expression of fibronectin, fibronectin iso-forms and integrin receptors in melanocytic lesions
    • Natali PG, Nicotra MR, Di Filippo F, et al. (1995) Expression of fibronectin, fibronectin iso-forms and integrin receptors in melanocytic lesions. Br J Cancer 71:1243-1247
    • (1995) Br J Cancer , vol.71 , pp. 1243-1247
    • Natali, P.G.1    Nicotra, M.R.2    Di Filippo, F.3
  • 160
    • 0024098975 scopus 로고
    • Molecular profile, tissue distribution and prognostic evaluation of a human melanoma-carcinoma antigen recognized by the murine monoclonal antibody B1.1
    • Natali PG, Nicotra MR, Nuti M et al. (1988) Molecular profile, tissue distribution and prognostic evaluation of a human melanoma-carcinoma antigen recognized by the murine monoclonal antibody B1.1. Int JBiol Markers 3:211-220
    • (1988) Int JBiol Markers , vol.3 , pp. 211-220
    • Natali, P.G.1    Nicotra, M.R.2    Nuti, M.3
  • 161
    • 0023108569 scopus 로고
    • Immunohistochemical detection of antigen in human primary and metastatic melanomas by the monoclonal antibody 140.240 and its possible prognostic significance
    • Natali PG, Roberts JT, Difilippo F et al. (1987) Immunohistochemical detection of antigen in human primary and metastatic melanomas by the monoclonal antibody 140.240 and its possible prognostic significance. Cancer 59:55-63
    • (1987) Cancer , vol.59 , pp. 55-63
    • Natali, P.G.1    Roberts, J.T.2    Difilippo, F.3
  • 162
    • 35349023688 scopus 로고    scopus 로고
    • Alpha-v-beta3 integrin expression in mela-nocytic nevi and cutaneous melanoma
    • Neto DS, Pantaleao L, de Sa BC et al. (2007) Alpha-v-beta3 integrin expression in mela-nocytic nevi and cutaneous melanoma. J Cutan Pathol 34:851-856
    • (2007) J Cutan Pathol , vol.34 , pp. 851-856
    • Neto, D.S.1    Pantaleao, L.2    De Sa, B.C.3
  • 163
    • 63549100184 scopus 로고    scopus 로고
    • Regulatory T-cell-mediated attenuation of T-cell responses to the NY-ESO-1 ISCOMA-TRIX vaccine in patients with advanced malignant melanoma
    • Nicholaou T, Ebert LM, Davis ID et al. (2009) Regulatory T-cell-mediated attenuation of T-cell responses to the NY-ESO-1 ISCOMA-TRIX vaccine in patients with advanced malignant melanoma. Clin Cancer Res15:2166-2173
    • (2009) Clin Cancer Res , vol.15 , pp. 2166-2173
    • Nicholaou, T.1    Ebert, L.M.2    Davis, I.D.3
  • 164
    • 33645080439 scopus 로고    scopus 로고
    • Apaf-1 expression in human cutaneous melanoma progression and in pigmentednevi
    • Niedojadlo K, Labedzka K, Lada E et al. (2006) Apaf-1 expression in human cutaneous melanoma progression and in pigmentednevi. Pigment Cell Res 19:43-50
    • (2006) Pigment Cell Res , vol.19 , pp. 43-50
    • Niedojadlo, K.1    Labedzka, K.2    Lada, E.3
  • 165
    • 0032973532 scopus 로고    scopus 로고
    • Prognostic evaluation of cutaneous malignant melanoma: A clinicopathologic and immunohistochemical study
    • Niezabitowski A, Czajecki K, Rys J et al. (1999) Prognostic evaluation of cutaneous malignant melanoma: a clinicopathologic and immunohistochemical study. J Surg Oncol 70:150-160
    • (1999) J Surg Oncol , vol.70 , pp. 150-160
    • Niezabitowski, A.1    Czajecki, K.2    Rys, J.3
  • 166
    • 0035038518 scopus 로고    scopus 로고
    • High collagenase-1 expression correlates with a favourable chemoimmunotherapy response in human metastatic melanoma
    • Nikkola J, Vihinen P, Vlaykova T et al. (2001) High collagenase-1 expression correlates with a favourable chemoimmunotherapy response in human metastatic melanoma. Melanoma Res 11:157-166
    • (2001) Melanoma Res , vol.11 , pp. 157-166
    • Nikkola, J.1    Vihinen, P.2    Vlaykova, T.3
  • 167
    • 0036466860 scopus 로고    scopus 로고
    • High expression levels of collagenase-1 and stromelysin-1 correlate with shorter disease-free survival in human metastatic melanoma
    • Nikkola J, Vihinen P, Vlaykova T et al. (2002) High expression levels of collagenase-1 and stromelysin-1 correlate with shorter disease-free survival in human metastatic melanoma. Int J Cancer 97:432-438
    • (2002) Int J Cancer , vol.97 , pp. 432-438
    • Nikkola, J.1    Vihinen, P.2    Vlaykova, T.3
  • 168
    • 38949171709 scopus 로고    scopus 로고
    • Activated leukocyte cell adhesion molecule: A new paradox in cancer
    • Ofori-Acquah SF, King JA (2008) Activated leukocyte cell adhesion molecule: a new paradox in cancer. Transl Res 151:122-128
    • (2008) Transl Res , vol.151 , pp. 122-128
    • Ofori-Acquah, S.F.1    King, J.A.2
  • 169
    • 33846913663 scopus 로고    scopus 로고
    • E-cadherin and beta-catenin expression patterns in malignant melanoma assessed by image analysis
    • Pecina-Slaus N, Zigmund M, Kusec V et al. (2007) E-cadherin and beta-catenin expression patterns in malignant melanoma assessed by image analysis. J Cutan Pathol 34:239-246
    • (2007) J Cutan Pathol , vol.34 , pp. 239-246
    • Pecina-Slaus, N.1    Zigmund, M.2    Kusec, V.3
  • 170
    • 41949118550 scopus 로고    scopus 로고
    • Pleiotrophin, a multifunctional angiogenic factor: Mechanisms and pathways in normal and pathological angiogenesis
    • Perez-Pinera P, Berenson JR, Deuel TF (2008) Pleiotrophin, a multifunctional angiogenic factor: mechanisms and pathways in normal and pathological angiogenesis. Curr Opin Hematol 15:210-214
    • (2008) Curr Opin Hematol , vol.15 , pp. 210-214
    • Perez-Pinera, P.1    Berenson, J.R.2    Deuel, T.F.3
  • 171
    • 0033890809 scopus 로고    scopus 로고
    • Amplification and overexpression of HER-2/ neu are uncommon in advanced stage melanoma
    • Persons DL, Arber DA, Sosman JA et al. (2000) Amplification and overexpression of HER-2/ neu are uncommon in advanced stage melanoma. Anticancer Res 20:1965-1968
    • (2000) Anticancer Res , vol.20 , pp. 1965-1968
    • Persons, D.L.1    Arber, D.A.2    Sosman, J.A.3
  • 172
    • 33747033102 scopus 로고    scopus 로고
    • Acral lentiginous melanoma: A clinicoprognostic study of 126 cases
    • Phan A, Touzet S, Dalle S et al. (2006) Acral lentiginous melanoma: a clinicoprognostic study of 126 cases. Br JDermatol 155:561-569
    • (2006) Br JDermatol , vol.155 , pp. 561-569
    • Phan, A.1    Touzet, S.2    Dalle, S.3
  • 173
    • 34047199411 scopus 로고    scopus 로고
    • CD31and CD34 expression as immunohistochem-ical markers of endothelial transdifferentia-tion in human cutaneous melanoma
    • Pisacane AM, Picciotto F, Risio M (2007) CD31and CD34 expression as immunohistochem-ical markers of endothelial transdifferentia-tion in human cutaneous melanoma. Cell Oncol 29:59-66
    • (2007) Cell Oncol , vol.29 , pp. 59-66
    • Pisacane, A.M.1    Picciotto, F.2    Risio, M.3
  • 174
    • 14844358974 scopus 로고    scopus 로고
    • VEGF and VEGFR-2 immunohistochemistry in human melanocy-tic naevi and cutaneous melanomas
    • Pisacane AM, Risio M (2005) VEGF and VEGFR-2 immunohistochemistry in human melanocy-tic naevi and cutaneous melanomas. Melanoma Res 15:39-43
    • (2005) Melanoma Res , vol.15 , pp. 39-43
    • Pisacane, A.M.1    Risio, M.2
  • 175
    • 0028967470 scopus 로고
    • Expression of cathepsin D in primary and metastatic human melanoma and dysplastic nevi
    • Podhajcer OL, Bover L, Bravo AI et al. (1995) Expression of cathepsin D in primary and metastatic human melanoma and dysplastic nevi. J Invest Dermatol 104:340-344
    • (1995) J Invest Dermatol , vol.104 , pp. 340-344
    • Podhajcer, O.L.1    Bover, L.2    Bravo, A.I.3
  • 176
    • 34250360586 scopus 로고    scopus 로고
    • Mechanisms of local immunosuppression in cutaneous melanoma
    • Polak ME, Borthwick NJ, Gabriel FG et al. (2007) Mechanisms of local immunosuppression in cutaneous melanoma. Br J Cancer 96:1879-1887
    • (2007) Br J Cancer , vol.96 , pp. 1879-1887
    • Polak, M.E.1    Borthwick, N.J.2    Gabriel, F.G.3
  • 177
    • 0345305205 scopus 로고    scopus 로고
    • Immunohisto-chemical determination of HER-2/neu in malignant melanoma
    • Potti A, Hille R, Koch M (2003a) Immunohisto-chemical determination of HER-2/neu in malignant melanoma. Anticancer Res 23:4067-4069
    • (2003) Anticancer Res , vol.23 , pp. 4067-4069
    • Potti, A.1    Hille, R.2    Koch, M.3
  • 178
    • 1542343818 scopus 로고    scopus 로고
    • Immunohistochemical determination of HER-2/neu, c-Kit (CD117), and vascular endothelial growth factor (VEGF) overex-pression in malignant melanoma
    • Potti A, Moazzam N, Langness E et al. (2004) Immunohistochemical determination of HER-2/neu, c-Kit (CD117), and vascular endothelial growth factor (VEGF) overex-pression in malignant melanoma. J Cancer Res Clin Oncol 130:80-86
    • (2004) J Cancer Res Clin Oncol , vol.130 , pp. 80-86
    • Potti, A.1    Moazzam, N.2    Langness, E.3
  • 179
    • 0345305220 scopus 로고    scopus 로고
    • Immunohistochemical determination of vascular endothelial growth factor (VEGF) over-expression in malignant melanoma
    • Potti A, Moazzam N, Tendulkar K et al. (2003b) Immunohistochemical determination of vascular endothelial growth factor (VEGF) over-expression in malignant melanoma. Anticancer Res 23:4023-4026
    • (2003) Anticancer Res , vol.23 , pp. 4023-4026
    • Potti, A.1    Moazzam, N.2    Tendulkar, K.3
  • 180
    • 12544257518 scopus 로고    scopus 로고
    • P21and Bax expression in cutaneous malignant melanomas: Correlation with histologic prognostic parameters
    • Poyraz A, Akyurek N, Gonul II et al. (2004) P21and Bax expression in cutaneous malignant melanomas: correlation with histologic prognostic parameters. J Exp Clin Cancer Res 23:625-631
    • (2004) J Exp Clin Cancer Res , vol.23 , pp. 625-631
    • Poyraz, A.1    Akyurek, N.2    Gonul, I.I.3
  • 181
    • 33845307569 scopus 로고    scopus 로고
    • Galectin-3 expression is associated with tumor progression and pattern of sun exposure in melanoma
    • Prieto VG, Mourad-Zeidan AA, Melnikova V et al. (2006) Galectin-3 expression is associated with tumor progression and pattern of sun exposure in melanoma. Clin Cancer Res 12:6709-6715
    • (2006) Clin Cancer Res , vol.12 , pp. 6709-6715
    • Prieto, V.G.1    Mourad-Zeidan, A.A.2    Melnikova, V.3
  • 182
    • 34447316207 scopus 로고    scopus 로고
    • Expression of VEGF(xxx)b, the inhibitory isoforms of VEGF, in malignant melanoma
    • Pritchard-Jones RO, Dunn DB, Qiu Y, et al. (2007) Expression of VEGF(xxx)b, the inhibitory isoforms of VEGF, in malignant melanoma. Br J Cancer 97:223-230
    • (2007) Br J Cancer , vol.97 , pp. 223-230
    • Pritchard-Jones, R.O.1    Dunn, D.B.2    Qiu, Y.3
  • 183
    • 41149096677 scopus 로고    scopus 로고
    • IMP-3is a novel progression marker in malignant melanoma
    • Pryor JG, Bourne PA, Yang Q et al. (2008) IMP-3is a novel progression marker in malignant melanoma. Mod Pathol 21:431-7c
    • (2008) Mod Pathol , vol.21
    • Pryor, J.G.1    Bourne, P.A.2    Yang, Q.3
  • 184
    • 0035717370 scopus 로고    scopus 로고
    • Immunohistochemical study of pepsinogen C expression in cutaneous malignant melanoma: Association with clinicopathological parameters
    • Quintela I, Vizoso F, Serra C et al. (2001) Immunohistochemical study of pepsinogen C expression in cutaneous malignant melanoma: association with clinicopathological parameters. Int J Biol Markers 16:240-244
    • (2001) Int J Biol Markers , vol.16 , pp. 240-244
    • Quintela, I.1    Vizoso, F.2    Serra, C.3
  • 185
    • 49249129411 scopus 로고    scopus 로고
    • Novel role for RGS1 in melanoma progression
    • Rangel J, Nosrati M, Leong SP, et al. (2008) Novel role for RGS1 in melanoma progression. AmJ Surg Pathol 32:1207-1212
    • (2008) Am J Surg Pathol , vol.32 , pp. 1207-1212
    • Rangel, J.1    Nosrati, M.2    Leong, S.P.3
  • 186
    • 23044479718 scopus 로고    scopus 로고
    • Expression and serum levels of MMP-2 and MMP-9 during human melanoma progression
    • Redondo P, Lloret P, Idoate M et al. (2005) Expression and serum levels of MMP-2 and MMP-9 during human melanoma progression. Clin Exp Dermatol 30:541-545
    • (2005) Clin Exp Dermatol , vol.30 , pp. 541-545
    • Redondo, P.1    Lloret, P.2    Idoate, M.3
  • 187
    • 0042133195 scopus 로고    scopus 로고
    • Immunologic escape and angiogen-esis in human malignant melanoma
    • Redondo P, Sanchez-Carpintero I, Bauza A et al. (2003) Immunologic escape and angiogen-esis in human malignant melanoma. JAmAcad Dermatol 49:255-263
    • (2003) J Am Acad Dermatol , vol.49 , pp. 255-263
    • Redondo, P.1    Sanchez-Carpintero, I.2    Bauza, A.3
  • 188
    • 0037334510 scopus 로고    scopus 로고
    • Neovascu-larisation, expression of fibroblast growth factor-2, and mast cells with tryptase activity increase simultaneously with pathological progression in human malignant melanoma
    • Ribatti D, Vacca A, Ria R et al. (2003) Neovascu-larisation, expression of fibroblast growth factor-2, and mast cells with tryptase activity increase simultaneously with pathological progression in human malignant melanoma. Eur J Cancer 39:666-674
    • (2003) Eur J Cancer , vol.39 , pp. 666-674
    • Ribatti, D.1    Vacca, A.2    Ria, R.3
  • 189
    • 12544259720 scopus 로고    scopus 로고
    • Bone morphogenic proteins are overex-pressed in malignant melanoma and promote cell invasion and migration
    • Rothhammer T, Poser I, Soncin F et al. (2005) Bone morphogenic proteins are overex-pressed in malignant melanoma and promote cell invasion and migration. Cancer Res 65:448-456
    • (2005) Cancer Res , vol.65 , pp. 448-456
    • Rothhammer, T.1    Poser, I.2    Soncin, F.3
  • 190
    • 0030829035 scopus 로고    scopus 로고
    • Enhanced expression of vascular endothelial growth factor in metastatic melanoma
    • Salven P, Heikkila P, Joensuu H (1997) Enhanced expression of vascular endothelial growth factor in metastatic melanoma. Br J Cancer 76:930-934 (Pubitemid 27401946)
    • (1997) British Journal of Cancer , vol.76 , Issue.7 , pp. 930-934
    • Salven, P.1    Heikkila, P.2    Joensuu, H.3
  • 191
    • 0007936466 scopus 로고    scopus 로고
    • Alterations in cadherin and catenin expression during the biological progression of melanocytic tumours
    • Sanders DS, Blessing K, Hassan GA et al. (1999) Alterations in cadherin and catenin expression during the biological progression of melanocytic tumours. Mol Pathol 52:151-157
    • (1999) Mol Pathol , vol.52 , pp. 151-157
    • Sanders, D.S.1    Blessing, K.2    Hassan, G.A.3
  • 192
    • 47749102962 scopus 로고    scopus 로고
    • Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis
    • Sauane M, Su ZZ, Gupta P et al. (2008) Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis. Proc Natl Acad Sci USA 105:9763-9768
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 9763-9768
    • Sauane, M.1    Su, Z.Z.2    Gupta, P.3
  • 193
    • 0027186037 scopus 로고
    • Tumour progression and metastatic behaviour in vivo correlates with integrin expression on melanocytic tumours
    • Schadendorf D, Gawlik C, Haney U, et al. (1993) Tumour progression and metastatic behaviour in vivo correlates with integrin expression on melanocytic tumours. J Pathol 170:429-434
    • (1993) J Pathol , vol.170 , pp. 429-434
    • Schadendorf, D.1    Gawlik, C.2    Haney, U.3
  • 194
    • 0028904388 scopus 로고
    • Association with clinical outcome of expression of VLA-4 in primary cutaneous malignant melanoma as well as P-selectin and E-selectin on intratumoral vessels
    • Schadendorf D, Heidel J, Gawlik C, et al. (1995a) Association with clinical outcome of expression of VLA-4 in primary cutaneous malignant melanoma as well as P-selectin and E-selectin on intratumoral vessels. J Natl Cancer Inst 87:366-371
    • (1995) J Natl Cancer Inst , vol.87 , pp. 366-371
    • Schadendorf, D.1    Heidel, J.2    Gawlik, C.3
  • 195
    • 0029102925 scopus 로고
    • Glutathione and related enzymes in tumor progression and metastases of human melanoma
    • Schadendorf D, Jurgovsky K, Kohlmus CM et al. (1995b) Glutathione and related enzymes in tumor progression and metastases of human melanoma. J Invest Dermatol 105:109-112
    • (1995) J Invest Dermatol , vol.105 , pp. 109-112
    • Schadendorf, D.1    Jurgovsky, K.2    Kohlmus, C.M.3
  • 196
    • 33750699609 scopus 로고    scopus 로고
    • Oestrogen receptor-beta expression in mel-anocytic lesions
    • Schmidt AN, Nanney LB, Boyd AS et al. (2006) Oestrogen receptor-beta expression in mel-anocytic lesions. Exp Dermatol 15:971-980
    • (2006) Exp Dermatol , vol.15 , pp. 971-980
    • Schmidt, A.N.1    Nanney, L.B.2    Boyd, A.S.3
  • 197
    • 3442883359 scopus 로고    scopus 로고
    • Reduction in Raf kinase inhibitor protein expression is associated with increased Ras-extracellular signal-regulated kinase signaling in melanoma cell lines
    • Schuierer MM, Bataille F, Hagan S et al. (2004) Reduction in Raf kinase inhibitor protein expression is associated with increased Ras-extracellular signal-regulated kinase signaling in melanoma cell lines. Cancer Res 64:5186-5192
    • (2004) Cancer Res , vol.64 , pp. 5186-5192
    • Schuierer, M.M.1    Bataille, F.2    Hagan, S.3
  • 198
    • 34147149679 scopus 로고    scopus 로고
    • Profiles of chemokine receptors in melanocytic lesions: De novo expression of CXCR6 in melanoma
    • Seidl H, Richtig E, Tilz H et al. (2007) Profiles of chemokine receptors in melanocytic lesions: de novo expression of CXCR6 in melanoma. Hum Pathol 38:768-780
    • (2007) Hum Pathol , vol.38 , pp. 768-780
    • Seidl, H.1    Richtig, E.2    Tilz, H.3
  • 199
    • 0141958794 scopus 로고    scopus 로고
    • Analysisof protein tyrosine kinase expression in melanocytic lesions by tissue array
    • Shen SS, Zhang PS, Eton O et al. (2003) Analysisof protein tyrosine kinase expression in melanocytic lesions by tissue array. J Cutan Pathol 30:539-547
    • (2003) J Cutan Pathol , vol.30 , pp. 539-547
    • Shen, S.S.1    Zhang, P.S.2    Eton, O.3
  • 200
    • 0028156863 scopus 로고
    • Immunohistological examination of the relationship between meta-static potential and expression of adhesion molecules and selectins on melanoma cells
    • Si Z, Hersey P (1994) Immunohistological examination of the relationship between meta-static potential and expression of adhesion molecules and selectins on melanoma cells. Pathology 26:6-15
    • (1994) Pathology , vol.26 , pp. 6-15
    • Si, Z.1    Hersey, P.2
  • 201
    • 50249166551 scopus 로고    scopus 로고
    • Cellular localization of EMMPRIN predicts prognosis of patients with operable lung adenocarcinoma independent from MMP-2 and MMP-9
    • Sienel W, Polzer B, Elshawi K et al. (2008) Cellular localization of EMMPRIN predicts prognosis of patients with operable lung adenocarcinoma independent from MMP-2 and MMP-9. Mod Pathol 21:1130-1138
    • (2008) Mod Pathol , vol.21 , pp. 1130-1138
    • Sienel, W.1    Polzer, B.2    Elshawi, K.3
  • 202
    • 0032413528 scopus 로고    scopus 로고
    • E-cadherin/catenin complex in benign and malignant melanocytic lesions
    • Silye R, Karayiannakis AJ, Syrigos KN et al. (1998) E-cadherin/catenin complex in benign and malignant melanocytic lesions. J Pathol 186:350-355
    • (1998) J Pathol , vol.186 , pp. 350-355
    • Silye, R.1    Karayiannakis, A.J.2    Syrigos, K.N.3
  • 203
    • 33646395923 scopus 로고    scopus 로고
    • Potential role of CCL27 and CCR10 expression in melanoma progression and immune escape
    • Simonetti O, Goteri G, Lucarini G et al. (2006) Potential role of CCL27 and CCR10 expression in melanoma progression and immune escape. Eur J Cancer 42:1181-1187
    • (2006) Eur J Cancer , vol.42 , pp. 1181-1187
    • Simonetti, O.1    Goteri, G.2    Lucarini, G.3
  • 204
    • 0036840543 scopus 로고    scopus 로고
    • Immunohistochemical expression of vascular endothelial growth factor, matrix metalloproteinase 2, and matrix metallopro-teinase 9 in cutaneous melanocytic lesions
    • Simonetti O, Lucarini G, Brancorsini D et al. (2002) Immunohistochemical expression of vascular endothelial growth factor, matrix metalloproteinase 2, and matrix metallopro-teinase 9 in cutaneous melanocytic lesions. Cancer 95:1963-1970
    • (2002) Cancer , vol.95 , pp. 1963-1970
    • Simonetti, O.1    Lucarini, G.2    Brancorsini, D.3
  • 205
    • 0032871384 scopus 로고    scopus 로고
    • Expression of interleukin-8 in primary and metastatic malignant melanoma of the skin
    • Singh RK, Varney ML, Bucana CD et al. (1999) Expression of interleukin-8 in primary and metastatic malignant melanoma of the skin. Melanoma Res 9:383-387
    • (1999) Melanoma Res , vol.9 , pp. 383-387
    • Singh, R.K.1    Varney, M.L.2    Bucana, C.D.3
  • 206
    • 0038242013 scopus 로고    scopus 로고
    • Increased expression of apoptotic markers in melanoma
    • Slater M, Scolyer RA, Gidley-Baird A et al. (2003) Increased expression of apoptotic markers in melanoma. Melanoma Res 13:137-145
    • (2003) Melanoma Res , vol.13 , pp. 137-145
    • Slater, M.1    Scolyer, R.A.2    Gidley-Baird, A.3
  • 207
    • 54449097809 scopus 로고    scopus 로고
    • Helper T-cell responses and clinical activity of a melanoma vaccine with multiple pep-tides from MAGE and melanocytic differentiation antigens
    • Slingluff CL Jr, Petroni GR, Olson W et al. (2008) Helper T-cell responses and clinical activity of a melanoma vaccine with multiple pep-tides from MAGE and melanocytic differentiation antigens. J Clin Oncol 26:4973-4980
    • (2008) J Clin Oncol , vol.26 , pp. 4973-4980
    • Slingluff Jr., C.L.1    Petroni, G.R.2    Olson, W.3
  • 208
    • 54549086871 scopus 로고    scopus 로고
    • The fatty acid binding protein 7 (FABP7) is involved in proliferation and invasion of melanoma cells
    • Slipicevic A, Jorgensen K, Skrede M et al. (2008) The fatty acid binding protein 7 (FABP7) is involved in proliferation and invasion of melanoma cells. BMC Cancer 8:276
    • (2008) BMC Cancer , vol.8 , pp. 276
    • Slipicevic, A.1    Jorgensen, K.2    Skrede, M.3
  • 209
    • 60849097255 scopus 로고    scopus 로고
    • Gene-expression signatures in breast cancer
    • Sotiriou C, Pusztai L (2009) Gene-expression signatures in breast cancer. N Engl J Med 360:790-800
    • (2009) N Engl J Med , vol.360 , pp. 790-800
    • Sotiriou, C.1    Pusztai, L.2
  • 210
    • 33847737677 scopus 로고    scopus 로고
    • Endothelin-1 and endothelin-3 promote invasive behavior via hypoxia-inducible fac-tor-1alpha in human melanoma cells
    • Spinella F, Rosano L, Di Castro V et al. (2007) Endothelin-1 and endothelin-3 promote invasive behavior via hypoxia-inducible fac-tor-1alpha in human melanoma cells. Cancer Res 67:1725-1734
    • (2007) Cancer Res , vol.67 , pp. 1725-1734
    • Spinella, F.1    Rosano, L.2    Di Castro, V.3
  • 211
    • 2142817158 scopus 로고    scopus 로고
    • Immunohistochemical expression of vascular endothelial growth factor (VEGF) and C-KIT in cutaneous melanocytic lesions
    • Stefanou D, Batistatou A, Zioga A et al. (2004) Immunohistochemical expression of vascular endothelial growth factor (VEGF) and C-KIT in cutaneous melanocytic lesions. Int J Surg Pathol 12:133-138
    • (2004) Int J Surg Pathol , vol.12 , pp. 133-138
    • Stefanou, D.1    Batistatou, A.2    Zioga, A.3
  • 212
    • 0035404270 scopus 로고    scopus 로고
    • Expresson of vascular endothelial growth factor, its receptors (FLT-1, KDR) and TSP-1 related to microvessel density and patient outcome in vertical growth phase melanomas
    • Straume O, Akslen LA (2001) Expresson of vascular endothelial growth factor, its receptors (FLT-1, KDR) and TSP-1 related to microvessel density and patient outcome in vertical growth phase melanomas. Am JPathol 159:223-235
    • (2001) Am J Pathol , vol.159 , pp. 223-235
    • Straume, O.1    Akslen, L.A.2
  • 213
    • 0036118459 scopus 로고    scopus 로고
    • Importance of vascular phenotype by basic fibroblast growth factor, and influence of the angio-genic factors basic fibroblast growth factor/ fibroblast growth factor receptor-1 and ephrin-A1/EphA2 on melanoma progression
    • Straume O, Akslen LA (2002) Importance of vascular phenotype by basic fibroblast growth factor, and influence of the angio-genic factors basic fibroblast growth factor/ fibroblast growth factor receptor-1 and ephrin-A1/EphA2 on melanoma progression. Am J Pathol 160:1009-1019
    • (2002) Am J Pathol , vol.160 , pp. 1009-1019
    • Straume, O.1    Akslen, L.A.2
  • 214
    • 0034716315 scopus 로고    scopus 로고
    • Prognostic value of pololike kinase expression in melanomas
    • Strebhardt K, Kneisel L, Linhart C et al. (2000) Prognostic value of pololike kinase expression in melanomas. JAMA 283:479-480
    • (2000) JAMA , vol.283 , pp. 479-480
    • Strebhardt, K.1    Kneisel, L.2    Linhart, C.3
  • 215
    • 51649124499 scopus 로고    scopus 로고
    • Clinicopatho-logic evaluation of immunohistochemical CD147 and MMP-2 expression in differentiated thyroid carcinoma
    • Tan H, Ye K, Wang Z et al. (2008) Clinicopatho-logic evaluation of immunohistochemical CD147 and MMP-2 expression in differentiated thyroid carcinoma. Jpn J Clin Oncol 38:528-533
    • (2008) Jpn J Clin Oncol , vol.38 , pp. 528-533
    • Tan, H.1    Ye, K.2    Wang, Z.3
  • 216
    • 46749136931 scopus 로고    scopus 로고
    • Endothelin-3 is produced by metastatic melanoma cells and promotes melanoma cell survival
    • Tang L, Su M, Zhang Y et al. (2008) Endothelin-3 is produced by metastatic melanoma cells and promotes melanoma cell survival. J Cutan Med Surg 12:64-70
    • (2008) J Cutan Med Surg , vol.12 , pp. 64-70
    • Tang, L.1    Su, M.2    Zhang, Y.3
  • 217
    • 0031850559 scopus 로고    scopus 로고
    • Expression of apoptosis regulators in cutaneous malignant melanoma
    • Tang L, Tron VA, Reed JC et al. (1998) Expression of apoptosis regulators in cutaneous malignant melanoma. Clin Cancer Res 4:1865-1871
    • (1998) Clin Cancer Res , vol.4 , pp. 1865-1871
    • Tang, L.1    Tron, V.A.2    Reed, J.C.3
  • 218
    • 33745065758 scopus 로고    scopus 로고
    • Standardization in immunohis-tochemistry: The role of antigen retrieval in molecular morphology
    • Taylor C (2006) Standardization in immunohis-tochemistry: the role of antigen retrieval in molecular morphology. Biotech Histochem 81:3-12
    • (2006) Biotech Histochem , vol.81 , pp. 3-12
    • Taylor, C.1
  • 219
    • 8144226019 scopus 로고    scopus 로고
    • Ets-1 transcription factor is widely expressed in benign and malignant melano-cytes and its expression has no significant association with prognosis
    • Torlakovic EE, Bilalovic N, Nesland JM et al. (2004) Ets-1 transcription factor is widely expressed in benign and malignant melano-cytes and its expression has no significant association with prognosis. Mod Pathol 17:1400-1406
    • (2004) Mod Pathol , vol.17 , pp. 1400-1406
    • Torlakovic, E.E.1    Bilalovic, N.2    Nesland, J.M.3
  • 220
  • 221
    • 36149001019 scopus 로고    scopus 로고
    • Involvement of E-cadherin, beta-catenin, Cdc42 and CXCR4 in the progression and prognosis of cutaneous melanoma
    • Tucci MG, Lucarini G, Brancorsini D et al. (2007) Involvement of E-cadherin, beta-catenin, Cdc42 and CXCR4 in the progression and prognosis of cutaneous melanoma. Br J Dermatol 157:1212-1216
    • (2007) Br J Dermatol , vol.157 , pp. 1212-1216
    • Tucci, M.G.1    Lucarini, G.2    Brancorsini, D.3
  • 222
    • 0027153138 scopus 로고
    • Melanocyte tumor progression is associated with changes in angiogenesis and expression of the 67-kilodalton laminin receptor
    • Vacca A, Ribatti D, Roncali L et al. (1993) Melanocyte tumor progression is associated with changes in angiogenesis and expression of the 67-kilodalton laminin receptor. Cancer 72:455-461
    • (1993) Cancer , vol.72 , pp. 455-461
    • Vacca, A.1    Ribatti, D.2    Roncali, L.3
  • 223
    • 0030014715 scopus 로고    scopus 로고
    • Melanoma-associated expression of transforming growth factor-beta isoforms
    • Van Belle P, Rodeck U, Nuamah I et al. (1996) Melanoma-associated expression of transforming growth factor-beta isoforms. Am J Pathol 148:1887-1894
    • (1996) Am J Pathol , vol.148 , pp. 1887-1894
    • Van Belle, P.1    Rodeck, U.2    Nuamah, I.3
  • 224
    • 13044277567 scopus 로고    scopus 로고
    • Progression-related expression of beta3 integrin in melanomas and nevi
    • Van Belle PA, Elenitsas R, Satyamoorthy K et al. (1999) Progression-related expression of beta3 integrin in melanomas and nevi. Hum Pathol 30:562-567
    • (1999) Hum Pathol , vol.30 , pp. 562-567
    • Van Belle, P.A.1    Elenitsas, R.2    Satyamoorthy, K.3
  • 225
    • 0030884405 scopus 로고    scopus 로고
    • Expression of gelatinase B and the extracellular matrix metalloproteinase indu-cer EMMPRIN in benign and malignant pigment cell lesions of the skin
    • van den Oord JJ, Paemen L, Opdenakker G et al. (1997) Expression of gelatinase B and the extracellular matrix metalloproteinase indu-cer EMMPRIN in benign and malignant pigment cell lesions of the skin. Am J Pathol 151:665-670
    • (1997) Am J Pathol , vol.151 , pp. 665-670
    • Van Den Oord, J.J.1    Paemen, L.2    Opdenakker, G.3
  • 226
    • 0033898112 scopus 로고    scopus 로고
    • Activated leukocyte cell adhesion molecule/CD166, a marker of tumor progression in primary malignant melanoma of the skin
    • van Kempen LC, van den Oord JJ, van Muijen GN et al. (2000) Activated leukocyte cell adhesion molecule/CD166, a marker of tumor progression in primary malignant melanoma of the skin. Am J Pathol 156:769-774
    • (2000) Am J Pathol , vol.156 , pp. 769-774
    • Van Kempen, L.C.1    Van Den Oord, J.J.2    Van Muijen, G.N.3
  • 227
    • 45549088075 scopus 로고    scopus 로고
    • Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule
    • van Kilsdonk JW, Wilting RH, Bergers M et al. (2008) Attenuation of melanoma invasion by a secreted variant of activated leukocyte cell adhesion molecule. Cancer Res 68: 3671-3679
    • (2008) Cancer Res , vol.68 , pp. 3671-3679
    • Van Kilsdonk, J.W.1    Wilting, R.H.2    Bergers, M.3
  • 228
    • 27644590410 scopus 로고    scopus 로고
    • Tumour-associated macrophage infiltration, neovascularization and aggressiveness in malignant melanoma: Role of monocyte chemotactic protein-1 and vascular endothe-lial growth factor-A
    • Varney ML, Johansson SL, Singh RK (2005) Tumour-associated macrophage infiltration, neovascularization and aggressiveness in malignant melanoma: role of monocyte chemotactic protein-1 and vascular endothe-lial growth factor-A. Melanoma Res 15:417-425
    • (2005) Melanoma Res , vol.15 , pp. 417-425
    • Varney, M.L.1    Johansson, S.L.2    Singh, R.K.3
  • 229
    • 31544456603 scopus 로고    scopus 로고
    • Distinct expression of CXCL8 and its receptors CXCR1 and CXCR2 and their association with vessel density and aggressiveness in malignant melanoma
    • Varney ML, Johansson SL, Singh RK (2006) Distinct expression of CXCL8 and its receptors CXCR1 and CXCR2 and their association with vessel density and aggressiveness in malignant melanoma. Am J Clin Pathol 125:209-216
    • (2006) Am J Clin Pathol , vol.125 , pp. 209-216
    • Varney, M.L.1    Johansson, S.L.2    Singh, R.K.3
  • 230
    • 34447508326 scopus 로고    scopus 로고
    • Expression of the cancer/testis antigen NY-ESO-1 in primary and metastatic malignant melanoma (MM)-correlation with prognostic factors
    • Velazquez EF, Jungbluth AA, Yancovitz M et al. (2007a) Expression of the cancer/testis antigen NY-ESO-1 in primary and metastatic malignant melanoma (MM)-correlation with prognostic factors. Cancer Immun 7:11
    • (2007) Cancer Immun , vol.7 , pp. 11
    • Velazquez, E.F.1    Jungbluth, A.A.2    Yancovitz, M.3
  • 231
    • 33846661807 scopus 로고    scopus 로고
    • Clinical relevance of neutral endo-peptidase (NEP/CD10) in melanoma
    • Velazquez EF, Yancovitz M, Pavlick A et al. (2007b) Clinical relevance of neutral endo-peptidase (NEP/CD10) in melanoma. JTransl Med 5:2
    • (2007) J Transl Med , vol.5 , pp. 2
    • Velazquez, E.F.1    Yancovitz, M.2    Pavlick, A.3
  • 232
    • 20044362387 scopus 로고    scopus 로고
    • Expression of galectin-3 in primary and metastatic melanoma: Immunohistochem-ical studies on human lesions and nude mice xenograft tumors
    • Vereecken P, Debray C, Petein M et al. (2005) Expression of galectin-3 in primary and metastatic melanoma: immunohistochem-ical studies on human lesions and nude mice xenograft tumors. Arch Dermatol Res 296:353-358
    • (2005) Arch Dermatol Res , vol.296 , pp. 353-358
    • Vereecken, P.1    Debray, C.2    Petein, M.3
  • 233
    • 0032933680 scopus 로고    scopus 로고
    • Prognostic value of tumour vascularity in metastatic melanoma and association of blood vessel density with vascular endothe-lial growth factor expression
    • Vlaykova T, Laurila P, Muhonen T et al. (1999) Prognostic value of tumour vascularity in metastatic melanoma and association of blood vessel density with vascular endothe-lial growth factor expression. Melanoma Res 9:59-68
    • (1999) Melanoma Res , vol.9 , pp. 59-68
    • Vlaykova, T.1    Laurila, P.2    Muhonen, T.3
  • 234
    • 34548507974 scopus 로고    scopus 로고
    • Matrix metalloproteinase induction in the tumor stroma does not depend on CD147 expression in murine B16 melanoma
    • Voigt H, Houben R, Schrama D et al. (2007) Matrix metalloproteinase induction in the tumor stroma does not depend on CD147 expression in murine B16 melanoma. Tumour Biol 28:229-237
    • (2007) Tumour Biol , vol.28 , pp. 229-237
    • Voigt, H.1    Houben, R.2    Schrama, D.3
  • 235
    • 63349095425 scopus 로고    scopus 로고
    • CD147 impacts angiogenesis and metastasis formation
    • Voigt H, Vetter-Kauczok CS, Schrama D et al. (2009) CD147 impacts angiogenesis and metastasis formation. Cancer Invest 27:329-333
    • (2009) Cancer Invest , vol.27 , pp. 329-333
    • Voigt, H.1    Vetter-Kauczok, C.S.2    Schrama, D.3
  • 236
    • 0027940293 scopus 로고
    • Estramustine binding protein in primary tumours and metastases of malignant melanoma
    • von Schoultz E, Carlstrom K, Henriksson R et al. (1994) Estramustine binding protein in primary tumours and metastases of malignant melanoma. Melanoma Res 4:401-405
    • (1994) Melanoma Res , vol.4 , pp. 401-405
    • Von Schoultz, E.1    Carlstrom, K.2    Henriksson, R.3
  • 237
    • 0242624586 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor-binding protein 2 in melanocytic lesions
    • Wang H, Shen SS, Wang H et al. (2003) Expression of insulin-like growth factor-binding protein 2 in melanocytic lesions. J Cutan Pathol 30:599-605
    • (2003) J Cutan Pathol , vol.30 , pp. 599-605
    • Wang, H.1    Shen, S.S.2    Wang, H.3
  • 238
    • 34547103985 scopus 로고    scopus 로고
    • Prognostic significance of nuclear ING3 expression in human cutaneous melanoma
    • Wang Y, Dai DL, Martinka M et al. (2007) Prognostic significance of nuclear ING3 expression in human cutaneous melanoma. Clin Cancer Res 13:4111-4116
    • (2007) Clin Cancer Res , vol.13 , pp. 4111-4116
    • Wang, Y.1    Dai, D.L.2    Martinka, M.3
  • 239
    • 34249105628 scopus 로고    scopus 로고
    • T-cell distribution and adhesion receptor expression in metastatic melanoma
    • Weishaupt C, Munoz KN, Buzney E et al. (2007) T-cell distribution and adhesion receptor expression in metastatic melanoma. Clin Cancer Res 13:2549-2556
    • (2007) Clin Cancer Res , vol.13 , pp. 2549-2556
    • Weishaupt, C.1    Munoz, K.N.2    Buzney, E.3
  • 240
    • 0030700840 scopus 로고    scopus 로고
    • Clinicopathological and prognostic relevance of Rap1-GAP expression in melano-cytic tumors
    • Weiss J, Biwer B, Schliz M et al. (1997) Clinicopathological and prognostic relevance of Rap1-GAP expression in melano-cytic tumors. Arch Dermatol Res 289: 573-577
    • (1997) Arch Dermatol Res , vol.289 , pp. 573-577
    • Weiss, J.1    Biwer, B.2    Schliz, M.3
  • 241
    • 33747619825 scopus 로고    scopus 로고
    • Expression and possible role of hPTTG1/securin in cutaneous malignant melanoma
    • Winnepenninckx V, Debiec-Rychter M, Belien JA et al. (2006a) Expression and possible role of hPTTG1/securin in cutaneous malignant melanoma. Mod Pathol 19: 1170-1180
    • (2006) Mod Pathol , vol.19 , pp. 1170-1180
    • Winnepenninckx, V.1    Debiec-Rychter, M.2    Belien, J.A.3
  • 242
    • 33645739022 scopus 로고    scopus 로고
    • Gene expression profiling of primary cutaneous melanoma and clinical outcome
    • Winnepenninckx V, Lazar V, Michiels S et al. (2006b) Gene expression profiling of primary cutaneous melanoma and clinical outcome. J Natl Cancer Inst 98:472-482
    • (2006) J Natl Cancer Inst , vol.98 , pp. 472-482
    • Winnepenninckx, V.1    Lazar, V.2    Michiels, S.3
  • 243
    • 42349093195 scopus 로고    scopus 로고
    • Wnt5a control of cell polarity and directional movement by polarized redistribution of adhesion receptors
    • Witze ES, Litman ES, Argast GM, et al.(2008) Wnt5a control of cell polarity and directional movement by polarized redistribution of adhesion receptors. Science 320:365-369
    • (2008) Science , vol.320 , pp. 365-369
    • Witze, E.S.1    Litman, E.S.2    Argast, G.M.3
  • 244
    • 0025836848 scopus 로고
    • The initial steps of tumor progression in melano-cytic lineage: A histochemical approach
    • Wollina U, Kilian U, Henkel U et al. (1991) The initial steps of tumor progression in melano-cytic lineage: a histochemical approach. Anticancer Res 11:1405-1414
    • (1991) Anticancer Res , vol.11 , pp. 1405-1414
    • Wollina, U.1    Kilian, U.2    Henkel, U.3
  • 245
    • 43849086306 scopus 로고    scopus 로고
    • Myeloid leukemia-1 expression in benign and malignant melanocytic lesions
    • Wong RP, Khosravi S, Martinka M et al. (2008) Myeloid leukemia-1 expression in benign and malignant melanocytic lesions. Oncol Rep 19:933-937
    • (2008) Oncol Rep , vol.19 , pp. 933-937
    • Wong, R.P.1    Khosravi, S.2    Martinka, M.3
  • 246
    • 0036786596 scopus 로고    scopus 로고
    • Stimulation and inhibition of uveal melanoma invasion by HGF, GRO, IL-1alpha and TGF-beta
    • Woodward JK, ElshawSR, Murray AK, et al. (2002) Stimulation and inhibition of uveal melanoma invasion by HGF, GRO, IL-1alpha and TGF-beta. Invest Ophthalmol Vis Sci 43:3144-3152
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 3144-3152
    • Woodward, J.K.1    Elshaw, S.R.2    Murray, A.K.3
  • 247
    • 13444310596 scopus 로고    scopus 로고
    • Pleiotrophin expression correlates with mel-anocytic tumor progression and metastatic potential
    • Wu H, Barusevicius A, Babb J et al. (2005) Pleiotrophin expression correlates with mel-anocytic tumor progression and metastatic potential. J Cutan Pathol 32:125-130
    • (2005) J Cutan Pathol , vol.32 , pp. 125-130
    • Wu, H.1    Barusevicius, A.2    Babb, J.3
  • 248
    • 0029900931 scopus 로고    scopus 로고
    • Expression of FGF1 and FGFR1 in human melanoma tissues
    • Xerri L, Battyani Z, GrobJJ, et al. (1996) Expression of FGF1 and FGFR1 in human melanoma tissues. Melanoma Res 6:223-230
    • (1996) Melanoma Res , vol.6 , pp. 223-230
    • Xerri, L.1    Battyani, Z.2    Grob, J.J.3
  • 249
    • 64949194262 scopus 로고    scopus 로고
    • Targeted IL-24 gene therapy inhibits cancer recurrence after liver tumor resection by inducing tumor cell apoptosis in nude mice
    • Yang YJ, Chen DZ, Li LX et al. (2009) Targeted IL-24 gene therapy inhibits cancer recur-rence after liver tumor resection by inducing tumor cell apoptosis in nude mice. Hepato-biliary Pancreat Dis Int 8:174-178
    • (2009) Hepato-biliary Pancreat Dis Int , vol.8 , pp. 174-178
    • Yang, Y.J.1    Chen, D.Z.2    Li, L.X.3
  • 250
    • 58749084501 scopus 로고    scopus 로고
    • Assessing the clinical utility of measuring insulin-like growth factor binding proteins in tissues and sera of melanoma patients
    • Yu JZ, Warycha MA, Christos PJ et al. (2008) Assessing the clinical utility of measuring insulin-like growth factor binding proteins in tissues and sera of melanoma patients. J Transl Med 6:70
    • (2008) J Transl Med , vol.6 , pp. 70
    • Yu, J.Z.1    Warycha, M.A.2    Christos, P.J.3
  • 251
    • 0032589324 scopus 로고    scopus 로고
    • Expression of catenins and p120cas in melanocytic nevi and cutaneous melanoma: Deficient alpha-cate-nin expression is associated with melanoma progression
    • Zhang XD, Hersey P (1999) Expression of catenins and p120cas in melanocytic nevi and cutaneous melanoma: deficient alpha-cate-nin expression is associated with melanoma progression. Pathology 31:239-246
    • (1999) Pathology , vol.31 , pp. 239-246
    • Zhang, X.D.1    Hersey, P.2
  • 252
    • 47549099788 scopus 로고    scopus 로고
    • Inhibition of alpha(4) integrin mediated adhesion was involved in the reduction of B16-F10 melanoma cells lung colonization in C57BL/6 mice treated with gambogic acid
    • Zhao J, Qi Q, Yang Y et al. (2008) Inhibition of alpha(4) integrin mediated adhesion was involved in the reduction of B16-F10 melanoma cells lung colonization in C57BL/6 mice treated with gambogic acid. Eur J Pharmacol 589:127-131
    • (2008) Eur J Pharmacol , vol.589 , pp. 127-131
    • Zhao, J.1    Qi, Q.2    Yang, Y.3
  • 253
    • 57749115016 scopus 로고    scopus 로고
    • Interleukin-24 overcomes temozolomide resistance and enhances cell death by down-regulation of O6-methylguanine-DNA methyltransferase in human melanoma cells
    • Zheng M, Bocangel D, Ramesh R et al. (2008) Interleukin-24 overcomes temozolomide resistance and enhances cell death by down-regulation of O6-methylguanine-DNA methyltransferase in human melanoma cells. Mol Cancer Ther 7:3842-3851
    • (2008) Mol Cancer Ther , vol.7 , pp. 3842-3851
    • Zheng, M.1    Bocangel, D.2    Ramesh, R.3
  • 254
    • 24044543035 scopus 로고    scopus 로고
    • Activation of the extracellular signal regulated kinase (ERK) pathway in human melanoma
    • Zhuang L, Lee CS, Scolyer RA et al. (2005) Activation of the extracellular signal regulated kinase (ERK) pathway in human melanoma. J Clin Pathol 58:1163-1169
    • (2005) J Clin Pathol , vol.58 , pp. 1163-1169
    • Zhuang, L.1    Lee, C.S.2    Scolyer, R.A.3
  • 255
    • 33947598446 scopus 로고    scopus 로고
    • Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanoma
    • Zhuang L, Lee CS, Scolyer RA et al. (2007) Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanoma. Mod Pathol 20:416-426
    • (2007) Mod Pathol , vol.20 , pp. 416-426
    • Zhuang, L.1    Lee, C.S.2    Scolyer, R.A.3
  • 256
    • 33646509028 scopus 로고    scopus 로고
    • Galectin-3 expression correlates with apop-tosis of tumor-associated lymphocytes in human melanoma biopsies
    • Zubieta MR, Furman D, Barrio M et al. (2006) Galectin-3 expression correlates with apop-tosis of tumor-associated lymphocytes in human melanoma biopsies. Am J Pathol 168:1666-1675
    • (2006) Am J Pathol , vol.168 , pp. 1666-1675
    • Zubieta, M.R.1    Furman, D.2    Barrio, M.3
  • 257
    • 38349176505 scopus 로고    scopus 로고
    • Evaluation of combined h-TERT, bcl-2, and caspases 3 and 8 expression in cutaneous malignant melanoma based on tissue micro-arrays and computerized image analysis
    • Zygouris P, Tsiambas E, Tiniakos D et al. (2007) Evaluation of combined h-TERT, bcl-2, and caspases 3 and 8 expression in cutaneous malignant melanoma based on tissue micro-arrays and computerized image analysis. J Buon 12:513-519
    • (2007) J Buon , vol.12 , pp. 513-519
    • Zygouris, P.1    Tsiambas, E.2    Tiniakos, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.