Numerical analysis of a magnetic nanoparticle-enhanced microfluidic surface-based bioassay

Microfluidics and Nanofluidics

Volumn 8, Issue 5, 2010, Pages 641-652

  Munir, Ahsan ^a   Wang, Jianlong ^a   Li, Zhonghong ^a   Zhou, H Susan ^a  

^a Worcester Polytechnic Institute   (United States)

Author keywords

Bio assay; Magnetic nanoparticles; Microfluidics; Modeling; Reaction kinetics

Indexed keywords

ANTIGEN-ANTIBODY BINDING; BINDING KINETICS; CONCENTRATION OF; CONCEPT STAGE; DESIGN PARAMETERS; DETECTION PERFORMANCE; DETECTION TIME; DEVELOPED MODEL; DIFFUSION TRANSPORT; FINITE ELEMENT TECHNIQUES; GENERIC STRATEGIES; MAGNETIC NANOPARTICLES; MASS TRANSPORT; MICROFLUIDIC PLATFORMS; MICROFLUIDICS MODELING; NUMERICAL MODELS; OPTIMIZED CONFIGURATION; PHYSICAL MEANS; RATE LIMITING; SENSING SURFACE; SURFACE-BASED;

ANTIBODIES; ANTIGENS; ASSOCIATION REACTIONS; BIOASSAY; CHEMICAL DETECTION; COMPUTER SIMULATION; DIFFUSION; MAGNETIC FIELDS; MAGNETIC MATERIALS; MICROFLUIDICS; NANOPARTICLES; NUMERICAL ANALYSIS; OPTIMIZATION; REACTION KINETICS; TARGETS; THERMOELECTRICITY;

NANOMAGNETICS;

EID: 77954758505     PISSN: 16134982     EISSN: 16134990     Source Type: Journal    
DOI: 10.1007/s10404-009-0497-3     Document Type: Article

References (48)

1. Abrantes M, Magone MT, Boyd LF, Schuck P (2001) Adaptation of a surface plasmon resonance biosensor with microfluidics for use with small sample volumes and long contact times. Anal Chem 73(13):2828-2835
2. Altschuh D, Oncul S, Demchenko AP (2006) Fluorescence sensing of intermolecular interactions and development of direct molecular biosensors. J Mol Recognit 19(6):459-477
3. Benn JA, Hu J, Hogan BJ, Fry RC, Samson LD, Thorsen T (2006) Comparative modeling and analysis of microfluidic and conventional DNA microarrays. Anal Biochem 348(2):284-293
4. Bhattacharyya A, Klapperich CM (2007) Design and testing of a disposable microfluidic chemiluminescent immunoassay for disease biomarkers in human serum samples. Biomed Microdevices 9(2):245-251
5. Bronzeau S, Pamme N (2008) Simultaneous bioassays in a microfluidic channel on plugs of different magnetic particles. Anal Chim Acta 609(1):105-112
6. Choi JW (2006) Fabrication of micromachined magnetic particle separators for bioseparation in microfluidic systems. In: Minteer SD (ed) Microfluidic techniques. Humana Press, Totowa, pp 65-81
7. COMSOL Multiphysics. ver. 3.3. COMSOL AB., Stockholm, Sweden (Online). Available: www.comsol.com
8. Dittmer WU, Kievit P, Prins M W J, Vissers J L M, Mersch M E C, Martens M F W C (2008) Sensitive and rapid immunoassay for parathyroid hormone using magnetic particle labels and magnetic actuation, J Immunol Methods 338:40-46
9. Friedrich D, Please C, Melvin T (2008) Optimisation of analyte transport in integrated microfluidic affinity sensors for the quantification of low levels of analyte. Sens Actuators B 131(1):323-332
10. Gervais T, Jensen KF (2006) Mass transport and surface reactions in microfluidic systems. Chem Eng Sci 61(4):1102-1121
11. Gijs M A M (2004) Magnetic bead handling on-chip: new opportunities for analytical applications. Microfluid Nanofluid 1(1):22-40
12. Goldstein B, Coombs D, He XY, Pineda AR, Wofsy C (1999) The influence of transport on the kinetics of binding to surface receptors: application to cells and BIAcore. J Mol Recognit 12(5):293-299
13. Haverkamp V, Ehrfeld W, Gebauer K, Hessel V, Lowe H, Richter T, Wille C (1999) The potential of micromixers for contacting of disperse liquid phases. Fresenius J Anal Chem 364:617-624
14. Hendrickson OD, Zherdev AV, Kaplun AP, Dzantiev BB (2003) Comparative analysis of models describing interactions between antibodies and liposomal antigens. Appl Biochem Microbiol 39:75-81
15. Heyries KA, Loughran MG, Hoffmann D, Homsy A, Blum LJ, Marquette CA (2008) Microfluidic biochip for chemiluminescent detection of allergen-specific antibodies. Biosens Bioelectron 23(12):1812-1818
16. Holden MA, Cremer PS (2005) Microfluidic tools for studying the specific binding, adsorption, and displacement of proteins at interfaces. Annu Rev Phys Chem 56:369-387
17. Hu GQ, Gao YL, Li DQ (2007) Modeling micropatterned antigen-antibody binding kinetics in a microfluidic chip. Biosens Bioelectron 22(7):1403-1409
18. Huang HZ, Ran PX, Liu ZQ (2007) Impedance sensing of allergen-antibody interaction on glassy carbon electrode modified by gold electrodeposition. Bioelectrochemistry 70(2):257-262
19. Jennissen HP, Zumbrink T (2004) A novel nanolayer biosensor principle. Biosens Bioelectron 19(9):987-997
20. Jiang Y, Wang PC, Locascio LE, Lee CS (2001) Integrated plastic microfluidic devices with ESI-MS for drug screening and residue analysis. Anal Chem 73(9):2048-2053
21. Kim DR, Zheng XL (2008) Numerical characterization and optimization of the microfluidics for nanowire biosensors. Nano Lett 8(10):3233-3237
22. Koch M, Witt H, Evans A G R, Brunnschweiler A (1999) Improved characterization technique for micromixers. J Micromech Microeng 9(2):156-158
23. Koets M, Wijk T, Eemeren J, Amerongen A, Prins M (2009) Rapid DNA multi-analyte immunoassay on a magneto-resistance biosensor. Biosens Bioelectron 24(7):1893-1898
24. Li GX, Joshi V, White RL, Wang SX, Kemp JT, Webb C, Davis RW, Sun SH (2003) Detection of single micron-sized magnetic bead and magnetic nanoparticles using spin valve sensor for biological applications. J Appl Phys 93(10):7557-7559
25. Lim YT, Cho MY, Choi BS, Lee JM, Chung BH (2008) Paramagnetic gold nanostructures for dual modal bioimaging and phototherapy of cancer cells. Chem Commun 40:4930-4932
26. Lisdat F, Schafer D (2008) The use of electrochemical impedance spectroscopy for biosensing. Anal Bioanal Chem 391(5):1555-1567
27. Ma KS, Zhou HS, Zoval J, Madou M (2006) DNA hybridization detection by label free versus impedance amplifying label with impedance spectroscopy. Sens Actuators B 114(1):58-64
28. Martins VC, Cardoso FA, Germano J, Cardoso S, Sousa L, Piedade M, Freitas PP, Fonseca LP (2009) Femtomolar limit of detection with a magnetoresistive biochip. Biosens Bioelectron 24:2690-2695
29. McDonald JC, Duffy DC, Anderson JR, Chiu DT, Wu HK, Schueller O J A, Whitesides GM (2000) Fabrication of microfluidic systems in poly (dimethyl siloxane). Electrophoresis 21(1):27-40
30. Munir A, Wang JL, Zhou SH (2009) Dynamics of capturing process of multiple magnetic nanoparticles in a flow through microfluidic bioseparation system. IET Nanobiotechnol 3(3):55-64
31. Myszka DG, He X, Dembo M, Morton TA, Goldstein B (1998) Extending the range of rate constants available from BIACORE: interpreting mass transport-influenced binding data. Biophys J 75(2):583-594
32. Nguyen NT, Wu ZG (2005) Micromixers-a review. J Micromech Microeng 15(2):R1-R16
33. Palecek E, Fojta M (2007) Magnetic beads as versatile tools for electrochemical DNA and protein biosensing. Talanta 74:276-290
34. Palecek E, Scheller F, Wang J (2005) Electrochemistry of nucleic acids and proteins: towards electrochemical sensors for genomics and proteomics, vol 1. Elsevier, Amsterdam
35. Pankhurst QA, Connolly J, Jones SK, Dobson J (2003) Applications of magnetic nanoparticles in biomedicine. J Phys D 36(13):R167-R181
36. Sheehan PE, Whitman LJ (2005) Detection limits for nanoscale biosensors. Nano Lett 5(4):803-807
37. Situma C, Hashimoto M, Soper SA (2006) Merging microfluidics with microarray-based bioassays. Biomol Eng 23(5):213-231
38. Stroock AD, Dertinger S K W, Ajdari A, Mezic I, Stone HA, Whitesides GM (2002) Chaotic mixer for microchannels. Science 295(5555):647-651
39. Suzuki H, Ho CM, Kasagi N (2004) A chaotic mixer for magnetic bead-based micro cell sorter. J Microelectromech Syst 13(5):779-790
40. Varshney M, Li YB, Srinivasan B, Tung S (2007) A label-free, microfluidics and interdigitated array microelectrode-based impedance biosensor in combination with nanoparticles immunoseparation for detection of Escherichia coli O157:H7 in food samples. Sens Actuators B 128(1):99-107 (Pubitemid 350051796)
41. Vijayendran RA, Motsegood KM, Beebe DJ, Leckband DE (2003) Evaluation of a three-dimensional micromixer in a surface-based biosensor. Langmuir 19(5):1824-1828
42. Wang SX, Li G (2008) Advances in giant magnetoresistance biosensors with magnetic nanoparticle tags: review and outlook. IEEE Trans Magn 44:1687-1702
43. Wang JL, Zhou HS (2008) Aptamer-based Au nanoparticlesenhanced surface plasmon resonance detection of small molecules. Anal Chem 80(18):7174-7178
44. Wang J, Xu D, Polsky R (2002) Magnetically-induced solid-state electrochemical detection of DNA hybridization. J Am Chem Soc 124:4208-4209 (Pubitemid 34441544)
45. Wang JL, Munir A, Zhou HS (2009) Au NPs-aptamer conjugates as a powerful competitive reagent for ultrasensitive detection of small molecules by surface plasmon resonance spectroscopy. Talanta 79:72-76
46. Wolf M, Michel B, Hunziker P, Delamarche E (2004) Simultaneous detection of C-reactive protein and other cardiac markers in human plasma using micromosaic immunoassays and selfregulating microfluidic networks. Biosens Bioelectron 19(10):1193-1202
47. Zhang W, Stone HA, Sherwood JD (1996) Mass transfer at a microelectrode in channel flow. J Phys Chem 100:9462-9464
48. Zimmermann M, Delamarche E, Wolf M, Hunziker P (2005) Modeling and optimization of high-sensitivity, low-volume microfluidic-based surface immunoassays. Biomed Microdevices 7(2):99-110