Modeling and optimization of high-sensitivity, low-volume microfluidic-based surface immunoassays

Biomedical Microdevices

Volumn 7, Issue 2, 2005, Pages 99-110

  Zimmermann, Martin ^a   Delamarche, Emmanuel ^b   Wolf, Marc ^a   Hunziker, Patrick ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b IBM RESEARCH ZURICH   (Switzerland)

Author keywords

High sensitivity; Lab on a chip; Low volume; Microfluidic; Surface immunoassay

Indexed keywords

ALGORITHMS; ANTIBODIES; BINDING ENERGY; DIAGNOSIS; ENZYME KINETICS; FINITE DIFFERENCE METHOD; IMMUNOLOGY;

IMMUNOASSAYS; MICROCHANNEL CAPTURE ANALYTES; MICROFLUIDICS; SURFACE DENSITY;

BIOASSAY;

ANTIBODY;

ALGORITHM; ANALYTIC METHOD; ARTICLE; BINDING KINETICS; BIOMEDICINE; CLINICAL RESEARCH; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; DIFFUSION; ELECTRONICS; FLOW KINETICS; FLOW RATE; IMMOBILIZATION; IMMUNOASSAY; MATHEMATICAL COMPUTING; MICROFLUIDICS; PRIORITY JOURNAL; PROCESS MODEL; PROCESS OPTIMIZATION; SENSITIVITY ANALYSIS; SURFACE PROPERTY; TECHNOLOGY; THEORETICAL MODEL; THERMODYNAMICS; TIME; TRANSPORT KINETICS;

ANTIGEN-ANTIBODY COMPLEX; BIOSENSING TECHNIQUES; COMPUTER-AIDED DESIGN; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; IMMUNOASSAY; KINETICS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MODELS, CHEMICAL; MODELS, IMMUNOLOGICAL; PROTEIN BINDING;

EID: 20944444560     PISSN: 13872176     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10544-005-1587-y     Document Type: Article

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