Development of a PCR/LDR/capillary electrophoresis assay with potential for the detection of a beta-thalassemia fetal mutation in maternal plasma

Journal of Maternal-Fetal and Neonatal Medicine

Volumn 23, Issue 8, 2010, Pages 920-927

  Yi, Ping ^a   Chen, Zhuqin ^a   Yu, Lili ^a   Zheng, Yingru ^a   Liu, Guodong ^a   Xie, Haichang ^a   Zhou, Yuanguo ^a   Zheng, Xiuhui ^a   Han, Jian ^a   Li, Li ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

capillary electrophoresis; ligase detection reaction; maternal plasma; Prenatal diagnosis

Indexed keywords

CELL DNA; CYTOSINE; GENE PRODUCT; NUCLEOTIDE; PROTEIN IVS2 654; THYMINE; UNCLASSIFIED DRUG; DNA; HEMOGLOBIN BETA CHAIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE;

ADULT; AMNION FLUID ANALYSIS; ANALYTIC METHOD; ARTICLE; BETA THALASSEMIA; CAPILLARY ELECTROPHORESIS; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DNA DETERMINATION; DNA TEMPLATE; FEASIBILITY STUDY; FEMALE; FETUS; HUMAN; INHERITANCE; LIGASE DETECTION REACTION; MALE; MATERNAL PLASMA; MUTATIONAL ANALYSIS; NUCLEIC ACID BASE SUBSTITUTION; POINT MUTATION; POLYMERASE CHAIN REACTION; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; BETA-THALASSEMIA; BLOOD; CHEMISTRY; DIAGNOSTIC USE; GENE VECTOR; GENETICS; MUTATION; PREGNANCY; PROCEDURES; SINGLE NUCLEOTIDE POLYMORPHISM; YOUNG ADULT;

ADULT; BETA-GLOBINS; BETA-THALASSEMIA; DNA; DNA LIGASES; ELECTROPHORESIS, CAPILLARY; FEMALE; GENETIC VECTORS; HUMANS; MALE; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; PRENATAL DIAGNOSIS; YOUNG ADULT;

EID: 77954721624     PISSN: 14767058     EISSN: 14764954     Source Type: Journal    
DOI: 10.3109/14767050903387060     Document Type: Article

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