Dedifferentiation derived cells exhibit phenotypic and functional characteristics of epidermal stem cells

Journal of Cellular and Molecular Medicine

Volumn 14, Issue 5, 2010, Pages 1135-1145

  Zhang, Cuiping ^a   Fu, Xiaobing ^a   Chen, Peng ^b   Bao, Xiaoxia ^a   Li, Fu ^a   Sun, Xiaoyan ^a   Lei, Yonghong ^a   Cai, Sa ^a   Sun, Tongzhu ^a   Sheng, Zhiyong ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

Author keywords

Characterization; Dedifferentiation; Epidermal cells; Epidermal stem cells; Isolation

Indexed keywords

BETA1 INTEGRIN; BIOLOGICAL MARKER; CYTOKERATIN 19; HOMEODOMAIN PROTEIN; NANOG PROTEIN, HUMAN; OCTAMER TRANSCRIPTION FACTOR 4; POU5F1 PROTEIN, HUMAN;

ANIMAL; ARTICLE; ARTIFICIAL SKIN; CELL DEDIFFERENTIATION; CELL PROLIFERATION; CELL SEPARATION; CHROMOSOME; CLONOGENIC ASSAY; CYTOLOGY; EPIDERMIS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MALE; METABOLISM; MOUSE; NUCLEOTIDE SEQUENCE; NUDE MOUSE; PHENOTYPE; POLYMERASE CHAIN REACTION; STEM CELL; TIME; TRANSPLANTATION; CFU COUNTING;

ANIMALS; ANTIGENS, CD29; BASE SEQUENCE; BIOLOGICAL MARKERS; CELL DEDIFFERENTIATION; CELL PROLIFERATION; CELL SEPARATION; CHROMOSOMES, MAMMALIAN; COLONY-FORMING UNITS ASSAY; EPIDERMIS; FEMALE; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; HUMANS; KERATIN-19; MALE; MICE; MICE, NUDE; OCTAMER TRANSCRIPTION FACTOR-3; PHENOTYPE; POLYMERASE CHAIN REACTION; SKIN, ARTIFICIAL; STEM CELLS; TIME FACTORS;

MUS;

EID: 77954715169     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2009.00765.x     Document Type: Article

References (38)

1. Horch RE, Kopp J, Kneser U. Tissue engineering of cultured skin substitutes. J Cell Mol Med. 2005, 9:592-608.
2. Kellouche S, Martin C, Korb G. Tissue engineering for full-thickness burns: a dermal substitute from bench to bedside. Biochem Biophys Res Commun. 2007, 363:472-8.
3. Xie JL, Li TZ, Qi SH. A study of using tissue-engineered skin reconstructed by candidate epidermal stem cells to cover the nude mice with full-thickness skin defect. J Plast Reconstr Aesthet Surg. 2007, 60:983-90.
4. Odelberg SJ, Kollhoff A, Keating MT. Dedifferentiation of mammalian myotubes induced by msx1. Cell. 2000, 103:1099-109.
5. McGann CJ, Odelberg SJ, Keating MT. Mammalian myotube dedifferentiation induced by newt regeneration extract. Proc Natl Acad Sci USA. 2001, 98:13699-704.
6. Chen X, Mao Z, Liu S. Dedifferentiation of adult human myoblasts induced by ciliary neurotrophic factor in vitro. Mol Biol Cell. 2005, 16:3140-51.
7. Chen S, Zhang Q, Wu X. Dedifferentiation of lineage-committed cells by a small molecule. J Am Chem Soc. 2004, 126:410-1.
8. Duckmanton A, Kumar A, Chang YT. A single-cell analysis of myogenic dedifferentiation induced by small molecules. Chem Biol. 2005, 12:1117-26.
9. Eggan K, Baldwin K, Tackett M. Mice cloned from olfactory sensory neurons. Nature. 2004, 428:44-9.
10. Li J, Ishii T, Feinstein P. Odorant receptor gene choice is reset by nuclear transfer from mouse olfactory sensory neurons. Nature. 2004, 428:393-9.
11. Lowry WE, Richter L, Yachechko R. Generation of human induced pluripotent stem cells from dermal fibroblasts. Proc Natl Acad Sci USA. 2008, 105:2883-8.
12. Yu J, Vodyanik MA, Smuga-Otto K. Induced pluripotent stem cell lines derived from human somatic cells. Science. 2007, 318:1917-20.
13. Pivarcsi A, Szell M, Kemeny L. Serum factors regulate the expression of the proliferation related genes α5 integrin and keratin1, but not keratin10 in HaCaT keratinocytes. Arch Dermatol Res. 2001, 293:206-13.
14. Fu X, Sun X, Li X. Dedifferentiation of epidermal cells to stem cells in vivo. Lancet. 2001, 358:1067-8.
15. Fu X, Sun X, Sun T. Epidermal growth factor induce the epithelial stem cell island formation in the regenerated epidermis. Zhonghua Yi Xue Za Zhi. 2001, 81:733-6.
16. Li H, Fu X, Zhang L. In vivo dedifferentiation of human epidermal cells. Cell Biol Int. 2007, 31:1436-41.
17. Liu Y, Zhou H, Gao F. Isolation and identification of stem cells from adult cashmere goat skin. Int J Dermatol. 2008, 47:551-6.
18. Kamolz LP, Kolbus A, Wick N. Cultured human epithelium: human umbilical cord blood stem cells differentiate into keratinocytes under in vitro conditions. Burns. 2006, 32:16-9.
19. Redvers RP, Li A, Kaur P. Side population in adult murine epidermis exhibits phenotypic and functional characteristics of keratinocyte stem cells. Proc Natl Acad Sci USA. 2006, 103:13168-73.
20. Regnier M, Patwardhan A, Scheynius A. Reconstructed human epidermis composed of keratinocytes, melanocytes and Langerhans cells. Med Biol Eng Comput. 1998, 36:821-4.
21. Jones PH, Watt FM. Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression. Cell. 1993, 73:713-24.
22. Kaur P, Li A. Adhesive properties of human basal epidermal cells: an analysis of keratinocyte stem cells, transit amplifying cells, and postmitotic differentiating cells. J Invest Dermatol. 2000, 114:413-20.
23. Tai MH, Chang CC, Kiupel M. Oct4 expression in adult human stem cells: evidence in support of the stem cell theory of carcinogenesis. Carcinogenesis. 2005, 26:495-502.
24. Helm J, Enkemann SA, Coppola D. Dedifferentiation precedes invasion in the progression from Barrett's metaplasia to esophageal adenocarcinoma. Clin Cancer Res. 2005, 11:2478-85.
25. Bouckenooghe T, Vandewalle B, Moerman E. Expression of progenitor cell markers during expansion of sorted human pancreatic beta cells. Gene Expr. 2005, 12:83-98.
26. Collas P. Dedifferentiation of cells: new approaches. Cytotherapy. 2007, 9:236-44.
27. Larouche D, Hayward C, Cuffley K. Keratin 19 as a stem cell marker in vivo and in vitro. Methods Mol Biol. 2005, 289:103-10.
28. Radu E, Simionescu O, Regalia T. Stem cells (p63+) in keratinocyte cultures from human adult skin. J Cell Mol Med. 2002, 6:593-8.
29. De Paiva CS, Pflugfelder SC, Li DQ. Cell size correlates with phenotype and proliferative capacity in human corneal epithelial cells. Stem Cells. 2006, 24:368-75.
30. Izumi K, Tobita T, Feinberg SE. Isolation of human oral keratinocyte progenitor/stem cells. J Dent Res. 2007, 86:341-6.
31. Jones PH, Watt FM. Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression. Cell. 1993, 73:713-24.
32. Marconi A, Dallaglio K, Lotti R. Survivin identifies keratinocyte stem cells and is downregulated by anti-beta1 integrin during anoikis. Stem Cells. 2007, 25:149-55.
33. Pesce M, Scholer HR. Oct-4: gatekeeper in the beginnings of mammalian development. Stem Cells. 2001, 19:271-8.
34. Mitsui K, Tokuzawa Y, Itoh H. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell. 2003, 113:631-42.
35. Zangrossi S, Marabese M, Broggini M. Oct-4 expression in adult human differentiated cells challenges its role as a pure stem cell marker. Stem Cells. 2007, 25:1675-80.
36. Papini S, Cecchetti D, Campani D. Isolation and clonal analysis of human epidermal keratinocyte stem cells in long-term culture. Stem Cells. 2003, 21:481-94.
37. Islam MS, Zhou H. Isolation and characterization of putative epidermal stem cells derived from Cashmere goat fetus. Eur J Dermatol. 2007, 17:302-8.
38. Riva F, Casasco A, Nespoli E. Generation of human epidermal constructs on a collagen layer alone. Tissue Eng. 2007, 13:2769-79.