Mechanism of verapamil action on wild-type and slow-channel mutant human muscle acetylcholine receptor

Journal of Neurochemistry

Volumn 114, Issue 4, 2010, Pages 1231-1240

  Moriconi, Claudia ^a   Di Castro, Maria Amalia ^a   Fucile, Sergio ^a,b   Eusebi, Fabrizio ^a,b   Grassi, Francesca ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b IRCCS NEUROMED   (Italy)

Author keywords

acetylcholine receptor channel kinetics; acetylcholine receptor channel modulation; end plate; nicotinic acetylcholine receptor; patch clamp; slow channel congenital myasthenic syndrome

Indexed keywords

ALANINE; CHOLINERGIC RECEPTOR; VALINE; VERAPAMIL; CALCIUM CHANNEL BLOCKING AGENT;

ARTICLE; CELL ADHESION; CELL MEMBRANE CONDUCTANCE; CONTROLLED STUDY; DRUG MECHANISM; GENE MUTATION; HUMAN; MUSCLE; MUTANT; PRIORITY JOURNAL; WILD TYPE; AMINO ACID SUBSTITUTION; CELL CULTURE; CHANNEL GATING; COMPARATIVE STUDY; DRUG EFFECTS; GENETICS; METABOLISM; MUTATION; NEUROMUSCULAR SYNAPSE; POINT MUTATION; REACTION TIME; SYNAPTIC MEMBRANE;

ANURA;

ALANINE; AMINO ACID SUBSTITUTION; CALCIUM CHANNEL BLOCKERS; CELLS, CULTURED; HUMANS; ION CHANNEL GATING; MUTATION; NEUROMUSCULAR JUNCTION; POINT MUTATION; REACTION TIME; RECEPTORS, CHOLINERGIC; SYNAPTIC MEMBRANES; VALINE; VERAPAMIL;

EID: 77954714417     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.06842.x     Document Type: Article

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