Complexes of bacterial nicotinate mononucleotide adenylyltransferase with inhibitors: Implication for structure-based drug design and improvement

Journal of Medicinal Chemistry

Volumn 53, Issue 14, 2010, Pages 5229-5239

  Huang, Nian ^a   Kolhatkar, Rohit ^b   Eyobo, Yvonne ^a   Sorci, Leonardo ^c   Rodionova, Irina ^c   Osterman, Andrei L ^c   MacKerell, Alexander D ^b   Zhang, Hong ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^c BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; ENZYME INHIBITOR; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINATE MONONUCLEOTIDE ADENYLYLTRANSFERASE; NICOTINATE MONONUCLEOTIDE ADENYLYLTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS ANTHRACIS; BACTERIAL GENE; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG STRUCTURE; ENZYME INHIBITION; ENZYME INHIBITOR COMPLEX; ENZYME STRUCTURE; NONHUMAN;

BACILLUS ANTHRACIS; BACTERIAL PROTEINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HYDRAZINES; HYDRAZONES; MODELS, MOLECULAR; NAPHTHALENES; NICOTINAMIDE-NUCLEOTIDE ADENYLYLTRANSFERASE; PROPIONATES;

EID: 77954712564     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm100377f     Document Type: Article

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