메뉴 건너뛰기




Volumn 11, Issue 6, 2010, Pages 451-457

Mechanism of action of two insect toxins huwentoxin-III and hainantoxin-VI on voltage-gated sodium channels

Author keywords

Dorsal unpaired median neurons; Insect neurotoxin; Sodium channel; Whole cell patch clamp technique

Indexed keywords

DELTA ATRACOTOXIN; HAINANTOXIN VI; HUWENTOXIN III; INSECT VENOM; SPIDER VENOM; TETRODOTOXIN; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL; SODIUM; SODIUM CHANNEL;

EID: 77954664528     PISSN: 16731581     EISSN: 18621783     Source Type: Journal    
DOI: 10.1631/jzus.B0900393     Document Type: Article
Times cited : (6)

References (25)
  • 1
    • 0242468736 scopus 로고    scopus 로고
    • Characterization of Amm VIII from Androctonus mauretanicus mauretanicus: A new scorpion toxin that discriminates between neuronal and skeletal sodium channels
    • [doi:10.1042/BJ20030688]
    • Alami, M., Vacher, H., Bosmans, F., Devaux, C., Rosso, J.P., Bougis, P.E., Tytgatt, J., Darbon, H., Martin-Eauclaire, M.F., 2003. Characterization of Amm VIII from Androctonus mauretanicus mauretanicus: a new scorpion toxin that discriminates between neuronal and skeletal sodium channels. Biochemical Journal, 375(3):551-560. [doi:10.1042/BJ20030688]
    • (2003) Biochemical Journal , vol.375 , Issue.3 , pp. 551-560
    • Alami, M.1    Vacher, H.2    Bosmans, F.3    Devaux, C.4    Rosso, J.P.5    Bougis, P.E.6    Tytgatt, J.7    Darbon, H.8    Martin-Eauclaire, M.F.9
  • 2
    • 0033694833 scopus 로고    scopus 로고
    • From ionic currents to molecular mechanisms: The structure and function of voltage-gated sodium channels
    • [doi:10.1016/S08 96-6273(00)81133-2]
    • Catterall, W.A., 2000. From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. Neuron, 26(1):13-25. [doi:10.1016/S08 96-6273(00)81133-2]
    • (2000) Neuron , vol.26 , Issue.1 , pp. 13-25
    • Catterall, W.A.1
  • 6
    • 0028298795 scopus 로고
    • Sodium channel blockade reduces hypoxic sodium loading and sodium-dependent calcium loading
    • Haigeny, M.C., Lakatta, E.G., Stern, M.D., Silverman, H.S., 1994. Sodium channel blockade reduces hypoxic sodium loading and sodium-dependent calcium loading. Circulation, 90(1):391-399.
    • (1994) Circulation , vol.90 , Issue.1 , pp. 391-399
    • Haigeny, M.C.1    Lakatta, E.G.2    Stern, M.D.3    Silverman, H.S.4
  • 7
    • 0346216979 scopus 로고    scopus 로고
    • Purification and characterization of a neurotoxic peptide huwentoxin-III and a natural inactive mutant from the venom of the spider Selenocosmia huwena Wang (Ornithoctonus huwena Wang)
    • Huang, R.H., Liu, Z.H., Liang, S.P., 2003. Purification and characterization of a neurotoxic peptide huwentoxin-III and a natural inactive mutant from the venom of the spider Selenocosmia huwena Wang (Ornithoctonus huwena Wang). Acta Biochimica et Biophysica Sinica, 35(11): 976-980.
    • (2003) Acta Biochimica et Biophysica Sinica , vol.35 , Issue.11 , pp. 976-980
    • Huang, R.H.1    Liu, Z.H.2    Liang, S.P.3
  • 8
    • 0346996705 scopus 로고    scopus 로고
    • Function and solution structure of hainantoxin-I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana
    • [doi:10.1016/S0014-5793(03)01303-6]
    • Li, D., Xiao, Y., Hu, W., Xie, J., Bosmans, F., Tytgat, J., Liang, S., 2003. Function and solution structure of hainantoxin-I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana. FEBS Letters, 555(3): 616-622. [doi:10.1016/S0014-5793(03)01303-6]
    • (2003) FEBS Letters , vol.555 , Issue.3 , pp. 616-622
    • Li, D.1    Xiao, Y.2    Hu, W.3    Xie, J.4    Bosmans, F.5    Tytgat, J.6    Liang, S.7
  • 9
    • 4444302484 scopus 로고    scopus 로고
    • Structure-activity relationships of hainantoxin-IV and structure determination of active and inactive sodium channel blockers
    • [doi:10.1074/jbc.M405765200]
    • Li, D.L., Xiao, Y.C., Xu, X., Xiong, X., Lu, S.Y., Liu, Z.H., Zhu, Q., Wang, M.C., Gu, X.C., Liang, S.P., 2004. Structure-activity relationships of hainantoxin-IV and structure determination of active and inactive sodium channel blockers. Journal of Biological Chemistry, 279(36): 37734-37740. [doi:10.1074/jbc.M405765200]
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.36 , pp. 37734-37740
    • Li, D.L.1    Xiao, Y.C.2    Xu, X.3    Xiong, X.4    Lu, S.Y.5    Liu, Z.H.6    Zhu, Q.7    Wang, M.C.8    Gu, X.C.9    Liang, S.P.10
  • 10
    • 18144392657 scopus 로고    scopus 로고
    • Enhancement of sodium metabisulfite on sodium currents in acutely isolated rat hippocampal CA1 neurons
    • [doi:10.1016/j.etap.2004. 10.003]
    • Meng, Z.Q., Nie, A.F., 2005. Enhancement of sodium metabisulfite on sodium currents in acutely isolated rat hippocampal CA1 neurons. Environmental Toxicology and Pharmacology, 20(1):35-41. [doi:10.1016/j.etap.2004. 10.003]
    • (2005) Environmental Toxicology and Pharmacology , vol.20 , Issue.1 , pp. 35-41
    • Meng, Z.Q.1    Nie, A.F.2
  • 11
    • 33847416219 scopus 로고    scopus 로고
    • Insect-selective spider toxins targeting voltage-gated sodium channels
    • [doi:10.1016/j.toxicon.2006.11.027]
    • Nicholson, G.M., 2007. Insect-selective spider toxins targeting voltage-gated sodium channels. Toxicon, 49(4):490-512. [doi:10.1016/j.toxicon. 2006.11.027]
    • (2007) Toxicon , vol.49 , Issue.4 , pp. 490-512
    • Nicholson, G.M.1
  • 12
    • 0031978687 scopus 로고    scopus 로고
    • Characterisation of the effects of robustoxin, the lethal neurotoxin from the Sydney funnel-web spider Atrax robustus, on sodium channel activation and inactivation
    • [doi:10.1007/s004240050612]
    • Nicholson, G.M., Walsh, R., Little, M.J., Tyler, M.I., 1998. Characterisation of the effects of robustoxin, the lethal neurotoxin from the Sydney funnel-web spider Atrax robustus, on sodium channel activation and inactivation. Pflugers Archiv-European Journal of Physiology, 436(1): 117-126. [doi:10.1007/s004240050612]
    • (1998) Pflugers Archiv-European Journal of Physiology , vol.436 , Issue.1 , pp. 117-126
    • Nicholson, G.M.1    Walsh, R.2    Little, M.J.3    Tyler, M.I.4
  • 13
    • 77952029496 scopus 로고    scopus 로고
    • Purification, sequencing and characterization of hainantoxin-VI, a neurotoxin from the Chinese bird spider Selenocosmia hainana
    • in Chinese
    • Pan, J.Y., Hu, W.J., Liang, S.P., 2002. Purification, sequencing and characterization of hainantoxin-VI, a neurotoxin from the Chinese bird spider Selenocosmia hainana. Zoological Research, 23(4):280-283 (in Chinese).
    • (2002) Zoological Research , vol.23 , Issue.4 , pp. 280-283
    • Pan, J.Y.1    Hu, W.J.2    Liang, S.P.3
  • 14
    • 0032922297 scopus 로고    scopus 로고
    • Augmentation of recovery from inactivation by site-3 Na channel toxins. A single-channel and whole-cell study of sustained currents
    • [doi:10.1085/jgp.113.2.333]
    • Richard Benzinger, G., Tonkovich, G.S., Hanck, D.A., 1999. Augmentation of recovery from inactivation by site-3 Na channel toxins. A single-channel and whole-cell study of sustained currents. The Journal of General Physiology, 113(2):333-346. [doi:10.1085/jgp.113.2.333]
    • (1999) The Journal of General Physiology , vol.113 , Issue.2 , pp. 333-346
    • Richard Benzinger, G.1    Tonkovich, G.S.2    Hanck, D.A.3
  • 15
    • 0030037704 scopus 로고    scopus 로고
    • + channel alpha subunit
    • [doi:10.1074/jbc.271.27.15950]
    • Rogers, J.C., Qu, Y., Tanada, T.N., Scheuer, T., Catterall, W.A., 1996. Molecular determinants of high affinity binding of alpha-scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na+ channel alpha subunit. Journal of Biological Chemistry, 271(27):15950-15962. [doi:10.1074/jbc.271.27.15950]
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.27 , pp. 15950-15962
    • Rogers, J.C.1    Qu, Y.2    Tanada, T.N.3    Scheuer, T.4    Catterall, W.A.5
  • 17
    • 0033040926 scopus 로고    scopus 로고
    • Purification and characterization of huwentoxin-II, a neurotoxic peptide from the venom of the Chinese bird spider Selenocosmia huwena
    • [doi:10.1034/j.1399- 3011.1999.00039.x]
    • Shu, Q., Liang, S.P., 1999. Purification and characterization of huwentoxin-II, a neurotoxic peptide from the venom of the Chinese bird spider Selenocosmia huwena. Journal of Peptide Research, 53(5):486-491. [doi:10.1034/j.1399- 3011.1999.00039.x]
    • (1999) Journal of Peptide Research , vol.53 , Issue.5 , pp. 486-491
    • Shu, Q.1    Liang, S.P.2
  • 18
    • 0034737415 scopus 로고    scopus 로고
    • Isolation and pharmacological characterisation of S-atracotoxin- Hv1b, a vertebrate-selective sodium channel toxin
    • [doi:10.1016/S0014-5793(00) 01339-9]
    • Szeto, T.H., Birinyi-Strachan, L.C., Smith, R.W., Connor, M., Christie, M.J., King, G., Nicholson, G.M., 2000. Isolation and pharmacological characterisation of S-atracotoxin- Hv1b, a vertebrate-selective sodium channel toxin. FEBS Letters, 470(3):293-299. [doi:10.1016/S0014-5793(00) 01339-9]
    • (2000) FEBS Letters , vol.470 , Issue.3 , pp. 293-299
    • Szeto, T.H.1    Birinyi-Strachan, L.C.2    Smith, R.W.3    Connor, M.4    Christie, M.J.5    King, G.6    Nicholson, G.M.7
  • 19
    • 0028979311 scopus 로고
    • + channels as targets for neuroprotective drugs
    • [doi:10.1016/S0165-6147(00) 890 60-4]
    • + channels as targets for neuroprotective drugs. Trends in Pharmacological Sciences, 16(9):309-316. [doi:10.1016/S0165-6147(00)890 60-4]
    • (1995) Trends in Pharmacological Sciences , vol.16 , Issue.9 , pp. 309-316
    • Taylor, C.P.1    Meldrum, B.2
  • 20
    • 34247470157 scopus 로고    scopus 로고
    • The cross channel activities of spider neurotoxin huwentoxin-I on rat dorsal root ganglion neurons
    • [doi:10.1016/j. bbrc.2007.02.168]
    • Wang, M.C., Guan, X., Liang, S.P., 2007. The cross channel activities of spider neurotoxin huwentoxin-I on rat dorsal root ganglion neurons. Biochemical and Biophysical Research Communications, 357(3):579-583. [doi:10.1016/j. bbrc.2007.02.168]
    • (2007) Biochemical and Biophysical Research Communications , vol.357 , Issue.3 , pp. 579-583
    • Wang, M.C.1    Guan, X.2    Liang, S.P.3
  • 22
    • 0037408077 scopus 로고    scopus 로고
    • Purification and characterization of hainantoxin-V, a tetrodotoxin-sensitive sodium channel inhibitor from the venom of the spider Selenocosmia hainana
    • [doi:10.1016/ S0041-0101(02)00280-5]
    • Xiao, Y.C., Liang, S.P., 2003a. Purification and characterization of hainantoxin-V, a tetrodotoxin-sensitive sodium channel inhibitor from the venom of the spider Selenocosmia hainana. Toxicon, 41(6):643-650. [doi:10.1016/ S0041-0101(02)00280-5]
    • (2003) Toxicon , vol.41 , Issue.6 , pp. 643-650
    • Xiao, Y.C.1    Liang, S.P.2
  • 23
    • 0347816398 scopus 로고    scopus 로고
    • + channels by two spider toxins: Hainantoxin-III and hainantoxin-IV
    • [doi:10.1016/S0014-2999(03) 02190-3]
    • + channels by two spider toxins: hainantoxin-III and hainantoxin-IV. European Journal of Pharmacology, 477(1):1-7. [doi:10.1016/S0014-2999(03) 02190-3]
    • (2003) European Journal of Pharmacology , vol.477 , Issue.1 , pp. 1-7
    • Xiao, Y.C.1    Liang, S.P.2
  • 25
    • 0033017102 scopus 로고    scopus 로고
    • The insect voltage-gated sodium channel as target of insecticides
    • DOI 10.1146/annurev.ento.44.1.429
    • Zlotkin, E., 1999. The insect voltage-gated sodium channel as target of insecticides. Annual Review of Entomology, 44(1):429-455. [doi:10.1146/annurev. ento.44.1.429] (Pubitemid 29096979)
    • (1999) Annual Review of Entomology , vol.44 , pp. 429-455
    • Zlotkin, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.