-
2
-
-
0016348695
-
Distinct haematological disorder with deletion of long arm of no. 5 chromosome
-
Van den Berghe H, Cassiman JJ, David G, Fryns JP, Michaux JL, Sokal G. Distinct haematological disorder with deletion of long arm of no. 5 chromosome. Nature 1974;251:437-438.
-
(1974)
Nature
, vol.251
, pp. 437-438
-
-
Van Den Berghe, H.1
Cassiman, J.J.2
David, G.3
Fryns, J.P.4
Michaux, J.L.5
Sokal, G.6
-
3
-
-
51449104487
-
Myelodysplastic syndromes associated with interstitial deletion of chromosome 5q: Clinicopathologic correlations and new insights from the pre-lenalidomide era
-
Holtan SG, Santana-Davila R, Dewald GW, Khetterling RP, Knudson RA, Hoyer JD et al. Myelodysplastic syndromes associated with interstitial deletion of chromosome 5q: clinicopathologic correlations and new insights from the pre-lenalidomide era. Am J Hematol 2008;83:708-713.
-
(2008)
Am. J. Hematol
, vol.83
, pp. 708-713
-
-
Holtan, S.G.1
Santana-Davila, R.2
Dewald, G.W.3
Khetterling, R.P.4
Knudson, R.A.5
Hoyer, J.D.6
-
4
-
-
10744229499
-
Clinical, morphological, cytogenetic, and prognostic features of patients with myelodysplastic syndromes and del (5q) including band q31
-
Giagounidis AA, Germing U, Haase S, Hildebrandt B, Schlegelberger B, Schoch C et al. Clinical, morphological, cytogenetic, and prognostic features of patients with myelodysplastic syndromes and del (5q) including band q31. Leukemia 2004;18:113-119.
-
(2004)
Leukemia
, vol.18
, pp. 113-119
-
-
Giagounidis, A.A.1
Germing, U.2
Haase, S.3
Hildebrandt, B.4
Schlegelberger, B.5
Schoch, C.6
-
5
-
-
70449378917
-
The heterogeneous prognosis of patients with myelodysplastic syndrome and chromosome 5 abnormalities: How does it relate to the original lenalidomide experience in MDS?
-
Kantarjian H, O'Brien S, Ravandi F, Borthakur G, Faderl S, Bueso-Ramos C et al. The heterogeneous prognosis of patients with myelodysplastic syndrome and chromosome 5 abnormalities: how does it relate to the original lenalidomide experience in MDS? Cancer 2009;115:5202-5209.
-
(2009)
Cancer
, vol.115
, pp. 5202-5209
-
-
Kantarjian, H.1
O'Brien, S.2
Ravandi, F.3
Borthakur, G.4
Faderl, S.5
Bueso-Ramos, C.6
-
6
-
-
33749438404
-
Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion
-
List A, Dewald G, Bennett J, Giagounidis A, Raza A, Feldman E et al. Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion. N Engl J Med 2006;355:1456-1465.
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 1456-1465
-
-
List, A.1
Dewald, G.2
Bennett, J.3
Giagounidis, A.4
Raza, A.5
Feldman, E.6
-
7
-
-
0027458441
-
The 5q-syndrome: A single-institution study of 43 consecutive patients
-
Mathew P, Tefferi A, Dewald GW, Goldberg SL, Su J, Hoagland HC et al. The 5q-syndrome: a single-institution study of 43 consecutive patients. Blood 1993;81:1040-1045.
-
(1993)
Blood
, vol.81
, pp. 1040-1045
-
-
Mathew, P.1
Tefferi, A.2
Dewald, G.W.3
Goldberg, S.L.4
Su, J.5
Hoagland, H.C.6
-
9
-
-
39749117093
-
Chromosome 5q deletion: Specific diagnoses and cytogenetic details among 358 consecutive cases from a single institution
-
Santana-Davila R, Holtan SG, Dewald GW, Ketterling RP, Knudson RA, Hanson CA et al. Chromosome 5q deletion: specific diagnoses and cytogenetic details among 358 consecutive cases from a single institution. Leuk Res 2008;32:407-411.
-
(2008)
Leuk Res.
, vol.32
, pp. 407-411
-
-
Santana-Davila, R.1
Holtan, S.G.2
Dewald, G.W.3
Ketterling, R.P.4
Knudson, R.A.5
Hanson, C.A.6
-
10
-
-
51649121491
-
Primary myelofibrosis is the most frequent myeloproliferative neoplasm associated with del (5q): Clinicopathologic comparison of del (5q)-positive and-negative cases
-
Santana-Davila R, Tefferi A, Holtan SG, Ketterling RP, Dewald GW, Knudson RA et al. Primary myelofibrosis is the most frequent myeloproliferative neoplasm associated with del (5q): clinicopathologic comparison of del (5q)-positive and-negative cases. Leuk Res 2008;32:1927-1930.
-
(2008)
Leuk Res.
, vol.32
, pp. 1927-1930
-
-
Santana-Davila, R.1
Tefferi, A.2
Holtan, S.G.3
Ketterling, R.P.4
Dewald, G.W.5
Knudson, R.A.6
-
11
-
-
0022255053
-
The efficacy of direct, 24-hour culture, and mitotic synchronization methods for cytogenetic analysis of bone marrow in neoplastic hematologic disorders
-
Dewald GW, Broderick DJ, Tom WW, Hagstrom JE, Pierre RV. The efficacy of direct, 24-hour culture, and mitotic synchronization methods for cytogenetic analysis of bone marrow in neoplastic hematologic disorders. Cancer Genet Cytogenet 1985;18:1-10.
-
(1985)
Cancer Genet. Cytogenet
, vol.18
, pp. 1-10
-
-
Dewald, G.W.1
Broderick, D.J.2
Tom, W.W.3
Hagstrom, J.E.4
Pierre, R.V.5
-
13
-
-
33750534561
-
MPL515 mutations in myeloproliferative and other myeloid disorders: A study of 1182 patients
-
Pardanani AD, Levine RL, Lasho T, Pikman Y, Mesa RA, Wadleigh M et al. MPL515 mutations in myeloproliferative and other myeloid disorders: a study of 1182 patients. Blood 2006;108:3472-3476.
-
(2006)
Blood
, vol.108
, pp. 3472-3476
-
-
Pardanani, A.D.1
Levine, R.L.2
Lasho, T.3
Pikman, Y.4
Mesa, R.A.5
Wadleigh, M.6
-
14
-
-
42449124578
-
Low JAK2V617F allele burden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survival
-
Tefferi A, Lasho TL, Huang J, Finke C, Mesa RA, Li CY et al. Low JAK2V617F allele burden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survival. Leukemia 2008;22:756-761.
-
(2008)
Leukemia
, vol.22
, pp. 756-761
-
-
Tefferi, A.1
Lasho, T.L.2
Huang, J.3
Finke, C.4
Mesa, R.A.5
Li, C.Y.6
-
15
-
-
65349150503
-
IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas
-
Watanabe T, Nobusawa S, Kleihues P, Ohgaki H. IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas. Am J Pathol 2009;174:1149-1153.
-
(2009)
Am. J. Pathol.
, vol.174
, pp. 1149-1153
-
-
Watanabe, T.1
Nobusawa, S.2
Kleihues, P.3
Ohgaki, H.4
-
16
-
-
70349653793
-
IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas
-
Nobusawa S, Watanabe T, Kleihues P, Ohgaki H. IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas. Clin Cancer Res 2009;15:6002-6007.
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 6002-6007
-
-
Nobusawa, S.1
Watanabe, T.2
Kleihues, P.3
Ohgaki, H.4
-
17
-
-
64849091680
-
Dysgranulopoiesis is an independent adverse prognostic factor in chronic myeloid disorders with an isolated interstitial deletion of chromosome 5q
-
Chen D, Hoyer JD, Ketterling RP, Tefferi A, Steensma DP, Holtan SG et al. Dysgranulopoiesis is an independent adverse prognostic factor in chronic myeloid disorders with an isolated interstitial deletion of chromosome 5q. Leukemia 2009;23:796-800.
-
(2009)
Leukemia
, vol.23
, pp. 796-800
-
-
Chen, D.1
Hoyer, J.D.2
Ketterling, R.P.3
Tefferi, A.4
Steensma, D.P.5
Holtan, S.G.6
-
18
-
-
54149085320
-
JAK2 and MPL mutations in myeloproliferative neoplasms: Discovery and science
-
Kilpivaara O, Levine RL. JAK2 and MPL mutations in myeloproliferative neoplasms: discovery and science. Leukemia 2008;22:1813-1817.
-
(2008)
Leukemia
, vol.22
, pp. 1813-1817
-
-
Kilpivaara, O.1
Levine, R.L.2
-
19
-
-
39749198165
-
JAK and MPL mutations in myeloid malignancies
-
Tefferi A. JAK and MPL mutations in myeloid malignancies. Leuk Lymphoma 2008;49:388-397.
-
(2008)
Leuk Lymphoma
, vol.49
, pp. 388-397
-
-
Tefferi, A.1
-
20
-
-
33745213401
-
The JAK2 V617F mutation identifies a subgroup of MDS patients with isolated deletion 5q and a proliferative bone marrow
-
Ingram W, Lea NC, Cervera J, Germing U, Fenaux P, Cassinat B et al. The JAK2 V617F mutation identifies a subgroup of MDS patients with isolated deletion 5q and a proliferative bone marrow. Leukemia 2006;20:1319-1321.
-
(2006)
Leukemia
, vol.20
, pp. 1319-1321
-
-
Ingram, W.1
Lea, N.C.2
Cervera, J.3
Germing, U.4
Fenaux, P.5
Cassinat, B.6
-
21
-
-
47649123488
-
Clinical correlates of JAK2V617F presence or allele burden in myeloproliferative neoplasms: A critical reappraisal
-
Vannucchi AM, Antonioli E, Guglielmelli P, Pardanani A, Tefferi A. Clinical correlates of JAK2V617F presence or allele burden in myeloproliferative neoplasms: a critical reappraisal. Leukemia 2008;22:1299-1307.
-
(2008)
Leukemia
, vol.22
, pp. 1299-1307
-
-
Vannucchi, A.M.1
Antonioli, E.2
Guglielmelli, P.3
Pardanani, A.4
Tefferi, A.5
-
22
-
-
77952097487
-
JAK2 (V617F) mutation in myelodysplastic syndrome (MDS) with del (5q) arises in genetically discordant clones
-
Sokol L, Caceres G, Rocha K, Stockero KJ, Dewald DW, List AF. JAK2 (V617F) mutation in myelodysplastic syndrome (MDS) with del (5q) arises in genetically discordant clones. Leuk Res 2010;34:821-823.
-
(2010)
Leuk Res.
, vol.34
, pp. 821-823
-
-
Sokol, L.1
Caceres, G.2
Rocha, K.3
Stockero, K.J.4
Dewald, D.W.5
List, A.F.6
-
23
-
-
75449119103
-
Somatic mutations of IDH1 and IDH2 in the leukemic transformation of myeloproliferative neoplasms
-
Green A, Beer P. Somatic mutations of IDH1 and IDH2 in the leukemic transformation of myeloproliferative neoplasms. N Engl J Med 2010;362:369-370.
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 369-370
-
-
Green, A.1
Beer, P.2
-
24
-
-
70149093912
-
Recurring mutations found by sequencing an acute myeloid leukemia genome
-
Mardis ER, Ding L, Dooling DJ, Larson DE, McLellan MD, Chen K et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med 2009;361:1058-1066.
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 1058-1066
-
-
Mardis, E.R.1
Ding, L.2
Dooling, D.J.3
Larson, D.E.4
McLellan, M.D.5
Chen, K.6
-
25
-
-
33746437130
-
MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia
-
Pikman Y, Lee BH, Mercher T, McDowell E, Ebert BL, Gozo M et al. MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia. PLoS Med 2006;3: e270.
-
(2006)
PLoS Med.
, vol.3
-
-
Pikman, Y.1
Lee, B.H.2
Mercher, T.3
McDowell, E.4
Ebert, B.L.5
Gozo, M.6
-
26
-
-
39749178544
-
Detection of three different MPLW515 mutations in 10.1% of all JAK2 V617 unmutated ET and 9.3% of all JAK2 V617F unmutated OMF: A study of 387 patients
-
Schnittger S, Haferlach C, Beelen DW, Bojko P, Dengler R, Diestelrath A et al. Detection of three different MPLW515 mutations in 10.1% of all JAK2 V617 unmutated ET and 9.3% of all JAK2 V617F unmutated OMF: a study of 387 patients. ASH Annu Meet Abstr 2007;110:2546.
-
(2007)
ASH Annu. Meet Abstr
, vol.110
, pp. 2546
-
-
Schnittger, S.1
Haferlach, C.2
Beelen, D.W.3
Bojko, P.4
Dengler, R.5
Diestelrath, A.6
-
27
-
-
39749170672
-
The clinical phenotype of patients with essential thrombocythemia harboring MPL 515W4L/K mutation
-
Vannucchi AM, Antonioli E, Pancrazzi A, Guglielmelli P, Di Lollo S, Alterini R et al. The clinical phenotype of patients with essential thrombocythemia harboring MPL 515W4L/K mutation. ASH Annu Meet Abstr 2007;110:678.
-
(2007)
ASH Annu. Meet Abstr
, vol.110
, pp. 678
-
-
Vannucchi, A.M.1
Antonioli, E.2
Pancrazzi, A.3
Guglielmelli, P.4
Di Lollo, S.5
Alterini, R.6
-
28
-
-
34047211223
-
Anaemia characterises patients with myelofibrosis harbouring Mpl mutation
-
Guglielmelli P, Pancrazzi A, Bergamaschi G, Rosti V, Villani L, Antonioli E et al. Anaemia characterises patients with myelofibrosis harbouring Mpl mutation. Br J Haematol 2007;137:244-247.
-
(2007)
Br. J. Haematol.
, vol.137
, pp. 244-247
-
-
Guglielmelli, P.1
Pancrazzi, A.2
Bergamaschi, G.3
Rosti, V.4
Villani, L.5
Antonioli, E.6
-
29
-
-
47249092413
-
MPL mutations in myeloproliferative disorders: Analysis of the PT-1 cohort
-
Beer PA, Campbell PJ, Scott LM, Bench AJ, Erber WN, Bareford D et al. MPL mutations in myeloproliferative disorders: analysis of the PT-1 cohort. Blood 2008;112:141-149.
-
(2008)
Blood
, vol.112
, pp. 141-149
-
-
Beer, P.A.1
Campbell, P.J.2
Scott, L.M.3
Bench, A.J.4
Erber, W.N.5
Bareford, D.6
-
30
-
-
50949127379
-
Characteristics and clinical correlates of MPL 515W4L/K mutation in essential thrombocythemia
-
Vannucchi AM, Antonioli E, Guglielmelli P, Pancrazzi A, Guerini V, Barosi G et al. Characteristics and clinical correlates of MPL 515W4L/K mutation in essential thrombocythemia. Blood 2008;112:844-847.
-
(2008)
Blood
, vol.112
, pp. 844-847
-
-
Vannucchi, A.M.1
Antonioli, E.2
Guglielmelli, P.3
Pancrazzi, A.4
Guerini, V.5
Barosi, G.6
-
31
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P et al. An integrated genomic analysis of human glioblastoma multiforme. Science 2008;321:1807-1812.
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
-
32
-
-
77649305610
-
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate
-
Ward PS, Patel J, Wise DR, Abdel-Wahab O, Bennett BD, Coller HA et al. The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell 2010;17:225-234.
-
(2010)
Cancer Cell.
, vol.17
, pp. 225-234
-
-
Ward, P.S.1
Patel, J.2
Wise, D.R.3
Abdel-Wahab, O.4
Bennett, B.D.5
Coller, H.A.6
-
33
-
-
77149134353
-
Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
-
Gross S, Cairns RA, Minden MD, Driggers EM, Bittinger MA, Jang HG et al. Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations. J Exp Med 2010;207:339-344.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 339-344
-
-
Gross, S.1
Cairns, R.A.2
Minden, M.D.3
Driggers, E.M.4
Bittinger, M.A.5
Jang, H.G.6
-
34
-
-
76549109434
-
Genetic analysis of transforming events that convert chronic myeloproliferative neoplasms to leukemias
-
Abdel-Wahab O, Manshouri T, Patel J, Harris K, Yao J, Hedvat C et al. Genetic analysis of transforming events that convert chronic myeloproliferative neoplasms to leukemias. Cancer Res 2010;70:447-452.
-
(2010)
Cancer Res.
, vol.70
, pp. 447-452
-
-
Abdel-Wahab, O.1
Manshouri, T.2
Patel, J.3
Harris, K.4
Yao, J.5
Hedvat, C.6
-
35
-
-
77954573304
-
IDH1 and IDH2 mutation analysis in chronic and blast phase myeloproliferative neoplasms
-
press
-
Pardanani A, Lasho T, Finke C, Mai M, McClure R, Tefferi A. IDH1 and IDH2 mutation analysis in chronic and blast phase myeloproliferative neoplasms. Leukemia 2010 (in press).
-
(2010)
Leukemia
-
-
Pardanani, A.1
Lasho, T.2
Finke, C.3
Mai, M.4
McClure, R.5
Tefferi, A.6
-
36
-
-
13444256401
-
Efficacy of lenalidomide in myelodysplastic syndromes
-
List A, Kurtin S, Roe DJ, Buresh A, Mahadevan D, Fuchs D et al. Efficacy of lenalidomide in myelodysplastic syndromes. N EnglJ Med 2005;352:549-557.
-
(2005)
N. EnglJ Med.
, vol.352
, pp. 549-557
-
-
List, A.1
Kurtin, S.2
Roe, D.J.3
Buresh, A.4
Mahadevan, D.5
Fuchs, D.6
-
37
-
-
77649303359
-
Patients with del (5q) MDS who fail to achieve sustained erythroid or cytogenetic remission after treatment with lenalidomide have an increased risk for clonal evolution and AML progression
-
Gohring G, Giagounidis A, Busche G, Kreipe HH, Zimmermann M, Hellstrom-Lindberg E et al. Patients with del (5q) MDS who fail to achieve sustained erythroid or cytogenetic remission after treatment with lenalidomide have an increased risk for clonal evolution and AML progression. Ann Hematol 2010;89:365-374.
-
(2010)
Ann. Hematol
, vol.89
, pp. 365-374
-
-
Gohring, G.1
Giagounidis, A.2
Busche, G.3
Kreipe, H.H.4
Zimmermann, M.5
Hellstrom-Lindberg, E.6
|