-
1
-
-
18044384874
-
-
American Cancer Society Atlanta, Ga, USA American Cancer Society
-
American Cancer Society, Cancer Facts and Figures 2005 Atlanta, Ga, USA American Cancer Society
-
Cancer Facts and Figures 2005
-
-
-
2
-
-
0033837509
-
Second-line chemotherapy for recurrent non-small cell lung cancer: Do new agents make a difference?
-
Ferrigno D., Buccheri G., Second-line chemotherapy for recurrent non-small cell lung cancer: do new agents make a difference? Lung Cancer 2000 29 2 91 104
-
(2000)
Lung Cancer
, vol.29
, Issue.2
, pp. 91-104
-
-
Ferrigno, D.1
Buccheri, G.2
-
5
-
-
33644891874
-
BCG immunotherapyfrom pathophysiology to clinical practice
-
Tishler M., Shoenfeld Y., BCG immunotherapyfrom pathophysiology to clinical practice Expert Opinion on Drug Safety 2006 5 2 225 229
-
(2006)
Expert Opinion on Drug Safety
, vol.5
, Issue.2
, pp. 225-229
-
-
Tishler, M.1
Shoenfeld, Y.2
-
6
-
-
35748942876
-
The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy
-
Apetoh L., Ghiringhelli F., Tesniere A., The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy Immunological Reviews 2007 220 1 47 59
-
(2007)
Immunological Reviews
, vol.220
, Issue.1
, pp. 47-59
-
-
Apetoh, L.1
Ghiringhelli, F.2
Tesniere, A.3
-
7
-
-
34547231172
-
Toll-like receptors in inflammation, infection and cancer
-
Chen K., Huang J., Gong W., Iribarren P., Dunlop N. M., Wang J. M., Toll-like receptors in inflammation, infection and cancer International Immunopharmacology 2007 7 10 1271 1285
-
(2007)
International Immunopharmacology
, vol.7
, Issue.10
, pp. 1271-1285
-
-
Chen, K.1
Huang, J.2
Gong, W.3
Iribarren, P.4
Dunlop, N.M.5
Wang, J.M.6
-
8
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H., Takeuchi O., Kawai T., A Toll-like receptor recognizes bacterial DNA Nature 2000 408 6813 740 745
-
(2000)
Nature
, vol.408
, Issue.6813
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
-
9
-
-
3242664636
-
Recognition of commensal microflora by Toll-like receptors is required for intestinal homeostasis
-
Rakoff-Nahoum S., Paglino J., Eslami-Varzaneh F., Edberg S., Medzhitov R., Recognition of commensal microflora by Toll-like receptors is required for intestinal homeostasis Cell 2004 118 2 229 241
-
(2004)
Cell
, vol.118
, Issue.2
, pp. 229-241
-
-
Rakoff-Nahoum, S.1
Paglino, J.2
Eslami-Varzaneh, F.3
Edberg, S.4
Medzhitov, R.5
-
10
-
-
61749098024
-
Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists
-
Vollmer J., Krieg A. M., Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists Advanced Drug Delivery Reviews 2009 61 3 195 204
-
(2009)
Advanced Drug Delivery Reviews
, vol.61
, Issue.3
, pp. 195-204
-
-
Vollmer, J.1
Krieg, A.M.2
-
11
-
-
0035815501
-
Vaccination with DNA containing tat coding sequences and unmethylated CpG motifs protects cynomolgus monkeys upon infection with simian/human immunodeficiency virus (SHIV89.6P)
-
2862-2877
-
Cafaro A., Titti F., Fracasso C., Vaccination with DNA containing tat coding sequences and unmethylated CpG motifs protects cynomolgus monkeys upon infection with simian/human immunodeficiency virus (SHIV89.6P) Vaccine 2001 19 2022 2862 2877
-
(2001)
Vaccine
, vol.19
, pp. 2022
-
-
Cafaro, A.1
Titti, F.2
Fracasso, C.3
-
12
-
-
0034087729
-
Successful treatment of intracranial gliomas in rat by oligodeoxynucleotides containing CpG motifs
-
Carpentier A. F., Xie J., Mokhtari K., Delattre J.-Y., Successful treatment of intracranial gliomas in rat by oligodeoxynucleotides containing CpG motifs Clinical Cancer Research 2000 6 6 2469 2473
-
(2000)
Clinical Cancer Research
, vol.6
, Issue.6
, pp. 2469-2473
-
-
Carpentier, A.F.1
Xie, J.2
Mokhtari, K.3
Delattre, J.-Y.4
-
13
-
-
0036917474
-
CpG DNA in the prevention and treatment of infections
-
Dalpke A., Zimmermann S., Heeg K., CpG DNA in the prevention and treatment of infections Bio Drugs 2002 16 6 419 431
-
(2002)
Bio Drugs
, vol.16
, Issue.6
, pp. 419-431
-
-
Dalpke, A.1
Zimmermann, S.2
Heeg, K.3
-
14
-
-
0035987294
-
Toll-like receptors: Their role in allergy and non-allergic inflammatory disease
-
Sabroe I., Parker L. C., Wilson A. G., Whyte M. K. B., Dower S. K., Toll-like receptors: their role in allergy and non-allergic inflammatory disease Clinical and Experimental Allergy 2002 32 7 984 989
-
(2002)
Clinical and Experimental Allergy
, vol.32
, Issue.7
, pp. 984-989
-
-
Sabroe, I.1
Parker, L.C.2
Wilson, A.G.3
Whyte, M.K.B.4
Dower, S.K.5
-
15
-
-
0032758720
-
Immunostimulatory DNA and applications to allergic disease
-
Van Uden J., Raz E., Immunostimulatory DNA and applications to allergic disease Journal of Allergy and Clinical Immunology 1999 104 5 902 910
-
(1999)
Journal of Allergy and Clinical Immunology
, vol.104
, Issue.5
, pp. 902-910
-
-
Van Uden, J.1
Raz, E.2
-
16
-
-
22944457857
-
Synthetic oligodeoxynucleotides containing deoxycytidyl-deoxyguanosine dinucleotides (CpG ODNs) and modified analogs as novel anticancer therapeutics
-
Wang H., Rayburn E., Zhang R., Synthetic oligodeoxynucleotides containing deoxycytidyl-deoxyguanosine dinucleotides (CpG ODNs) and modified analogs as novel anticancer therapeutics Current Pharmaceutical Design 2005 11 22 2889 2907
-
(2005)
Current Pharmaceutical Design
, vol.11
, Issue.22
, pp. 2889-2907
-
-
Wang, H.1
Rayburn, E.2
Zhang, R.3
-
17
-
-
0029984358
-
CpG motifs present in bacterial DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon
-
Klinman D. M., Yi A.-K., Beaucage S. L., Conover J., Krieg A. M., CpG motifs present in bacterial DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon Proceedings of the National Academy of Sciences of the United States of America 1996 93 7 2879 2883
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.7
, pp. 2879-2883
-
-
Klinman, D.M.1
Yi, A.-K.2
Beaucage, S.L.3
Conover, J.4
Krieg, A.M.5
-
18
-
-
1842631153
-
Immunotherapeutic uses of CpG oligodeoxynucleotides
-
Klinman D. M., Immunotherapeutic uses of CpG oligodeoxynucleotides Nature Reviews Immunology 2004 4 4 249 258
-
(2004)
Nature Reviews Immunology
, vol.4
, Issue.4
, pp. 249-258
-
-
Klinman, D.M.1
-
19
-
-
0036219195
-
CpG motifs in bacterial DNA and their immune effects
-
Krieg A. M., CpG motifs in bacterial DNA and their immune effects Annual Review of Immunology 2002 20 709 760
-
(2002)
Annual Review of Immunology
, vol.20
, pp. 709-760
-
-
Krieg, A.M.1
-
20
-
-
0742289969
-
Signal transduction pathways mediated by the interaction of CpG DNA with Toll-like receptor 9
-
Takeshita F., Gursel I., Ishii K. J., Suzuki K., Gursel M., Klinman D. M., Signal transduction pathways mediated by the interaction of CpG DNA with Toll-like receptor 9 Seminars in Immunology 2004 16 1 17 22
-
(2004)
Seminars in Immunology
, vol.16
, Issue.1
, pp. 17-22
-
-
Takeshita, F.1
Gursel, I.2
Ishii, K.J.3
Suzuki, K.4
Gursel, M.5
Klinman, D.M.6
-
21
-
-
22944457857
-
Synthetic oligodeoxynucleotides containing deoxycytidyl-deoxyguanosine dinucleotides (CpG ODNs) and modified analogs as novel anticancer therapeutics
-
Wang H., Rayburn E., Zhang R., Synthetic oligodeoxynucleotides containing deoxycytidyl-deoxyguanosine dinucleotides (CpG ODNs) and modified analogs as novel anticancer therapeutics Current Pharmaceutical Design 2005 11 22 2889 2907
-
(2005)
Current Pharmaceutical Design
, vol.11
, Issue.22
, pp. 2889-2907
-
-
Wang, H.1
Rayburn, E.2
Zhang, R.3
-
22
-
-
21044444274
-
Immunomodulatory oligonucleotides containing a cytosine-phosphate- 2 ′ -deoxy-7-deazaguanosine motif as potent Toll-like receptor 9 agonists
-
Kandimalla E. R., Bhagat L., Li Y., Immunomodulatory oligonucleotides containing a cytosine-phosphate- 2 ′ -deoxy-7-deazaguanosine motif as potent Toll-like receptor 9 agonists Proceedings of the National Academy of Sciences of the United States of America 2005 102 19 6925 6930
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.19
, pp. 6925-6930
-
-
Kandimalla, E.R.1
Bhagat, L.2
Li, Y.3
-
23
-
-
10744227784
-
A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif
-
Kandimalla E. R., Bhagat L., Zhu F.-G., A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif Proceedings of the National Academy of Sciences of the United States of America 2003 100 2 14303 14308
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.2
, pp. 14303-14308
-
-
Kandimalla, E.R.1
Bhagat, L.2
Zhu, F.-G.3
-
24
-
-
17044399617
-
Oligodeoxynucleotides containing synthetic immunostimulatory motifs augment potent Th1 immune responses to HBsAg in mice
-
Li Y., Kandimalla E. R., Yu D., Agrawal S., Oligodeoxynucleotides containing synthetic immunostimulatory motifs augment potent Th1 immune responses to HBsAg in mice International Immunopharmacology 2005 5 6 981 991
-
(2005)
International Immunopharmacology
, vol.5
, Issue.6
, pp. 981-991
-
-
Li, Y.1
Kandimalla, E.R.2
Yu, D.3
Agrawal, S.4
-
26
-
-
0037809185
-
Divergent synthetic nucleotide motif recognition pattern: Design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles
-
Kandimalla E. R., Bhagat L., Wang D., Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles Nucleic Acids Research 2003 31 9 2393 2400
-
(2003)
Nucleic Acids Research
, vol.31
, Issue.9
, pp. 2393-2400
-
-
Kandimalla, E.R.1
Bhagat, L.2
Wang, D.3
-
27
-
-
0036384444
-
Potent CpG oligonucleotides containing phosphodiester linkages: In vitro and in vivo immunostimulatory properties
-
Yu D., Zhu F.-G., Bhagat L., Potent CpG oligonucleotides containing phosphodiester linkages: in vitro and in vivo immunostimulatory properties Biochemical and Biophysical Research Communications 2002 297 1 83 90
-
(2002)
Biochemical and Biophysical Research Communications
, vol.297
, Issue.1
, pp. 83-90
-
-
Yu, D.1
Zhu, F.-G.2
Bhagat, L.3
-
28
-
-
34548183510
-
CPG-7909 (PF-3512676, ProMune): Toll-like receptor-9 agonist in cancer therapy
-
Murad Y. M., Clay T. M., Lyerly H. K., Morse M. A., CPG-7909 (PF-3512676, ProMune): Toll-like receptor-9 agonist in cancer therapy Expert Opinion on Biological Therapy 2007 7 8 1257 1266
-
(2007)
Expert Opinion on Biological Therapy
, vol.7
, Issue.8
, pp. 1257-1266
-
-
Murad, Y.M.1
Clay, T.M.2
Lyerly, H.K.3
Morse, M.A.4
-
29
-
-
34547231172
-
Toll-like receptors in inflammation, infection and cancer
-
Chen K., Huang J., Gong W., Iribarren P., Dunlop N. M., Wang J. M., Toll-like receptors in inflammation, infection and cancer International Immunopharmacology 2007 7 10 1271 1285
-
(2007)
International Immunopharmacology
, vol.7
, Issue.10
, pp. 1271-1285
-
-
Chen, K.1
Huang, J.2
Gong, W.3
Iribarren, P.4
Dunlop, N.M.5
Wang, J.M.6
-
31
-
-
0030475607
-
A role for the interferon-inducible protein 10 in inhibition of angiogenesis by interleukin-12
-
DOI 10.1111/j.1749-6632.1996.tb52664.x
-
Angiolillo A. L., Sgadari C., Tosato G., A role for the interferon-inducible protein 10 in inhibition of angiogenesis by interleukin-12 Annals of the New York Academy of Sciences 1996 795 158 167
-
(1996)
Annals of the New York Academy of Sciences
, vol.795
, pp. 158-167
-
-
Angiolillo, A.L.1
Sgadari, C.2
Tosato, G.3
-
32
-
-
0030797704
-
Antisense oligonucleotide inhibitors for the treatment of cancer. Pharmacokinetic properties of phosphorothioate oligodeoxynucleotides
-
Geary R. S., Leeds J. M., Henry S. P., Monteith D. K., Levin A. A., Antisense oligonucleotide inhibitors for the treatment of cancer. Pharmacokinetic properties of phosphorothioate oligodeoxynucleotides Anti-Cancer Drug Design 1997 12 5 383 393
-
(1997)
Anti-Cancer Drug Design
, vol.12
, Issue.5
, pp. 383-393
-
-
Geary, R.S.1
Leeds, J.M.2
Henry, S.P.3
Monteith, D.K.4
Levin, A.A.5
-
33
-
-
55249083982
-
Phase 1 evaluation of intralesionally injected TLR9-agonist PF-3512676 in patients with basal cell carcinoma or metastatic melanoma
-
Hofmann M. A., Kors C., Audring H., Walden P., Sterry W., Trefzer U., Phase 1 evaluation of intralesionally injected TLR9-agonist PF-3512676 in patients with basal cell carcinoma or metastatic melanoma Journal of Immunotherapy 2008 31 5 520 527
-
(2008)
Journal of Immunotherapy
, vol.31
, Issue.5
, pp. 520-527
-
-
Hofmann, M.A.1
Kors, C.2
Audring, H.3
Walden, P.4
Sterry, W.5
Trefzer, U.6
-
34
-
-
70449127697
-
Safety and efficacy of PF-3512676 for the treatment of stage IV renal cell carcinoma: An open-label, multicenter phase I/II study
-
Thompson J. A., Kuzel T., Drucker B. J., Urba W., Bukowski R., Safety and efficacy of PF-3512676 for the treatment of stage IV renal cell carcinoma: an open-label, multicenter phase I/II study Clinical Genitourinary Cancer 2009 7 3 E58 E65
-
(2009)
Clinical Genitourinary Cancer
, vol.7
, Issue.3
-
-
Thompson, J.A.1
Kuzel, T.2
Drucker, B.J.3
Urba, W.4
Bukowski, R.5
-
35
-
-
35948987594
-
Phase i trial of Toll-like receptor 9 agonist PF-3512676 with and following rituximab in patients with recurrent indolent and aggressive non-Hodgkin's lymphoma
-
Leonard J. P., Link B. K., Emmanouilides C., Phase I trial of Toll-like receptor 9 agonist PF-3512676 with and following rituximab in patients with recurrent indolent and aggressive non-Hodgkin's lymphoma Clinical Cancer Research 2007 13 20 6168 6174
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.20
, pp. 6168-6174
-
-
Leonard, J.P.1
Link, B.K.2
Emmanouilides, C.3
-
36
-
-
33748683549
-
Oligodeoxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma
-
Link B. K., Ballas Z. K., Weisdorf D., Oligodeoxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma Journal of Immunotherapy 2006 29 5 558 568
-
(2006)
Journal of Immunotherapy
, vol.29
, Issue.5
, pp. 558-568
-
-
Link, B.K.1
Ballas, Z.K.2
Weisdorf, D.3
-
38
-
-
71849087609
-
Phase i study of TLR9 agonist PF-3512676 in combination with carboplatin and paclitaxel in patients with advanced non-small-cell lung cancer
-
Yamada K., Nakao M., Fukuyama C., Phase I study of TLR9 agonist PF-3512676 in combination with carboplatin and paclitaxel in patients with advanced non-small-cell lung cancer Cancer Science 2010 101 1 188 195
-
(2010)
Cancer Science
, vol.101
, Issue.1
, pp. 188-195
-
-
Yamada, K.1
Nakao, M.2
Fukuyama, C.3
-
39
-
-
34248148289
-
CPG 7909, a TLR9 agonist, added to first line taxane/platinum for advanced non-small cell lung cancer, a randomized, controlled phase II study
-
abstract 7036
-
Leichman G., Gravenor D., Woytowitz D., CPG 7909, a TLR9 agonist, added to first line taxane/platinum for advanced non-small cell lung cancer, a randomized, controlled phase II study Journal of Clinical Oncology 2005 23 16S. abstract 7036
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.16 S
-
-
Leichman, G.1
Gravenor, D.2
Woytowitz, D.3
-
40
-
-
50549084485
-
Randomized phase II trial of a Toll-like receptor 9 agonist oligodeoxynucleotide, PF-3512676, in combination with first-line taxane plus platinum chemotherapy for advanced-stage non-small-cell lung cancer
-
Manegold C., Gravenor D., Woytowitz D., Randomized phase II trial of a Toll-like receptor 9 agonist oligodeoxynucleotide, PF-3512676, in combination with first-line taxane plus platinum chemotherapy for advanced-stage non-small-cell lung cancer Journal of Clinical Oncology 2008 26 24 3979 3986
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.24
, pp. 3979-3986
-
-
Manegold, C.1
Gravenor, D.2
Woytowitz, D.3
-
42
-
-
66149099493
-
Randomized phase III trial of paclitaxel/carboplatin with or without PF-3512676 as first line treatment of advanced non-small cell lung cancer (NSCLC)
-
supplement abstract no. 8016
-
Hirsh V., Boyer M., Rosell R., Randomized phase III trial of paclitaxel/carboplatin with or without PF-3512676 as first line treatment of advanced non-small cell lung cancer (NSCLC) Journal of Clinical Oncology 2008 26 supplement. abstract no. 8016
-
(2008)
Journal of Clinical Oncology
, vol.26
-
-
Hirsh, V.1
Boyer, M.2
Rosell, R.3
-
43
-
-
66149099493
-
Randomized phase III trial of gemcitabine/cisplatin with or without PF-3512676 as first line treatment of advanced non-small cell lung cancer (NSCLC)
-
abstract no. 8017
-
Manegold C., Thatcher N., Benner R. J., Randomized phase III trial of gemcitabine/cisplatin with or without PF-3512676 as first line treatment of advanced non-small cell lung cancer (NSCLC) Journal of Clinical Oncology 2008 26. abstract no. 8017
-
(2008)
Journal of Clinical Oncology
, vol.26
-
-
Manegold, C.1
Thatcher, N.2
Benner, R.J.3
-
44
-
-
73849154636
-
The saga of thalidomide. Neuropathy to embryopathy, with case reports of congenital anomalies
-
Mellin G. W., Katzenstein M., The saga of thalidomide. Neuropathy to embryopathy, with case reports of congenital anomalies The New England Journal of Medicine 1962 267 1184 1192
-
(1962)
The New England Journal of Medicine
, vol.267
, pp. 1184-1192
-
-
Mellin, G.W.1
Katzenstein, M.2
-
45
-
-
0023789457
-
Thalidomide update: Regulatory aspects
-
Kelsey F. O., Thalidomide update: regulatory aspects Teratology 1988 38 3 221 226
-
(1988)
Teratology
, vol.38
, Issue.3
, pp. 221-226
-
-
Kelsey, F.O.1
-
46
-
-
0028216334
-
Thalidomide is an inhibitor of angiogenesis
-
D'Amato R. J., Loughnan M. S., Flynn E., Folkman J., Thalidomide is an inhibitor of angiogenesis Proceedings of the National Academy of Sciences of the United States of America 1994 91 9 4082 4085
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.9
, pp. 4082-4085
-
-
D'Amato, R.J.1
Loughnan, M.S.2
Flynn, E.3
Folkman, J.4
-
47
-
-
0031171663
-
Effects of thalidomide and related metabolites in a mouse corneal model of neovascularization
-
Kenyon B. M., Browne F., D'Amato R. J., Effects of thalidomide and related metabolites in a mouse corneal model of neovascularization Experimental Eye Research 1997 64 6 971 978
-
(1997)
Experimental Eye Research
, vol.64
, Issue.6
, pp. 971-978
-
-
Kenyon, B.M.1
Browne, F.2
D'Amato, R.J.3
-
49
-
-
28844472902
-
Lenalidomide and thalidomide: Mechanisms of actionsimilarities and differences
-
supplement 4
-
Anderson K. C., Lenalidomide and thalidomide: mechanisms of actionsimilarities and differences Seminars in Hematology 2005 42 supplement 4 S3 S8
-
(2005)
Seminars in Hematology
, vol.42
-
-
Anderson, K.C.1
-
50
-
-
41149168649
-
Lenalidomide for the treatment of B-cell malignancies
-
Chanan-Khan A. A., Cheson B. D., Lenalidomide for the treatment of B-cell malignancies Journal of Clinical Oncology 2008 26 9 1544 1552
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.9
, pp. 1544-1552
-
-
Chanan-Khan, A.A.1
Cheson, B.D.2
-
51
-
-
0033532557
-
Amino-substituted thalidomide analogs: Potent inhibitors of TNF-alpha production
-
Muller G. W., Chen R., Huang S.-Y., Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production Bioorganic and Medicinal Chemistry Letters 1999 9 11 1625 1630
-
(1999)
Bioorganic and Medicinal Chemistry Letters
, vol.9
, Issue.11
, pp. 1625-1630
-
-
Muller, G.W.1
Chen, R.2
Huang, S.-Y.3
-
52
-
-
0029762175
-
Potent inhibition of tumor necrosis factor-alpha production by tetrafluorothalidomide and tetrafluorophthalimides
-
Niwayama S., Turk B. E., Liu J. O., Potent inhibition of tumor necrosis factor-alpha production by tetrafluorothalidomide and tetrafluorophthalimides Journal of Medicinal Chemistry 1996 39 16 3044 3045
-
(1996)
Journal of Medicinal Chemistry
, vol.39
, Issue.16
, pp. 3044-3045
-
-
Niwayama, S.1
Turk, B.E.2
Liu, J.O.3
-
53
-
-
0033168605
-
Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha
-
Corral L. G., Haslett P. A. J., Muller G. W., Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha Journal of Immunology 1999 163 1 380 386
-
(1999)
Journal of Immunology
, vol.163
, Issue.1
, pp. 380-386
-
-
Corral, L.G.1
Haslett, P.A.J.2
Muller, G.W.3
-
54
-
-
1942534043
-
The evolution of thalidomide and its IMiD derivatives as anticancer agents
-
Bartlett J. B., Dredge K., Dalgleish A. G., The evolution of thalidomide and its IMiD derivatives as anticancer agents Nature Reviews Cancer 2004 4 4 314 322
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.4
, pp. 314-322
-
-
Bartlett, J.B.1
Dredge, K.2
Dalgleish, A.G.3
-
55
-
-
0032726481
-
Immunomodulation by thalidomide and thalidomide analogues
-
supplement 1
-
Corral L. G., Kaplan G., Immunomodulation by thalidomide and thalidomide analogues Annals of the Rheumatic Diseases 1999 58 supplement 1 I107 I113
-
(1999)
Annals of the Rheumatic Diseases
, vol.58
-
-
Corral, L.G.1
Kaplan, G.2
-
56
-
-
67349107194
-
The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells
-
Galustian C., Meyer B., Labarthe M.-C., The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells Cancer Immunology Immunotherapy 2009 58 7 1033 1045
-
(2009)
Cancer Immunology Immunotherapy
, vol.58
, Issue.7
, pp. 1033-1045
-
-
Galustian, C.1
Meyer, B.2
Labarthe, M.-C.3
-
57
-
-
0037021257
-
Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects
-
Dredge K., Marriott J. B., Macdonald C. D., Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects British Journal of Cancer 2002 87 10 1166 1172
-
(2002)
British Journal of Cancer
, vol.87
, Issue.10
, pp. 1166-1172
-
-
Dredge, K.1
Marriott, J.B.2
MacDonald, C.D.3
-
58
-
-
77949315484
-
Combination of novel proteasome inhibitor NPI-0052 and lenalidomide trigger in vitro and in vivo synergistic cytotoxicity in multiple myeloma
-
Chauhan D., Singh A. V., Ciccarelli B., Richardson P. G., Palladino M. A., Anderson K. C., Combination of novel proteasome inhibitor NPI-0052 and lenalidomide trigger in vitro and in vivo synergistic cytotoxicity in multiple myeloma Blood 2010 115 4 834 845
-
(2010)
Blood
, vol.115
, Issue.4
, pp. 834-845
-
-
Chauhan, D.1
Singh, A.V.2
Ciccarelli, B.3
Richardson, P.G.4
Palladino, M.A.5
Anderson, K.C.6
-
59
-
-
60449115552
-
The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions
-
Lu L., Payvandi F., Wu L., The anti-cancer drug lenalidomide inhibits angiogenesis and metastasis via multiple inhibitory effects on endothelial cell function in normoxic and hypoxic conditions Microvascular Research 2009 77 2 78 86
-
(2009)
Microvascular Research
, vol.77
, Issue.2
, pp. 78-86
-
-
Lu, L.1
Payvandi, F.2
Wu, L.3
-
60
-
-
34547925624
-
Combination therapy targeting the tumor microenvironment is effective in a model of human ocular melanoma
-
Mangiameli D. P., Blansfield J. A., Kachala S., Combination therapy targeting the tumor microenvironment is effective in a model of human ocular melanoma Journal of Translational Medicine 2007 5, article 38
-
(2007)
Journal of Translational Medicine
, vol.538
-
-
Mangiameli, D.P.1
Blansfield, J.A.2
Kachala, S.3
-
61
-
-
0035195019
-
Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: Therapeutic applications
-
Gupta D., Treon S. P., Shima Y., Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applications Leukemia 2001 15 12 1950 1961
-
(2001)
Leukemia
, vol.15
, Issue.12
, pp. 1950-1961
-
-
Gupta, D.1
Treon, S.P.2
Shima, Y.3
-
62
-
-
0037089554
-
S-3-amino-phthalimido-glutarimide inhibits angiogenesis and growth of B-cell neoplasias in mice
-
Lentzsch S., Rogers M. S., LeBlanc R., S-3-amino-phthalimido-glutarimide inhibits angiogenesis and growth of B-cell neoplasias in mice Cancer Research 2002 62 8 2300 2305
-
(2002)
Cancer Research
, vol.62
, Issue.8
, pp. 2300-2305
-
-
Lentzsch, S.1
Rogers, M.S.2
Leblanc, R.3
-
63
-
-
74549224367
-
Results of a multicenter, randomized, double-blind phase 2/3 study of lenalidomide in the treatment of pretreated relapsed or refractory metastatic malignant melanoma
-
Eisen T., Trefzer U., Hamilton A., Results of a multicenter, randomized, double-blind phase 2/3 study of lenalidomide in the treatment of pretreated relapsed or refractory metastatic malignant melanoma Cancer 2010 116 1 146 154
-
(2010)
Cancer
, vol.116
, Issue.1
, pp. 146-154
-
-
Eisen, T.1
Trefzer, U.2
Hamilton, A.3
-
65
-
-
67049171301
-
Phase i study of oral lenalidomide in patients with refractory metastatic cancer
-
Dahut W. L., Aragon-Ching J. B., Woo S., Phase I study of oral lenalidomide in patients with refractory metastatic cancer Journal of Clinical Pharmacology 2009 49 6 650 660
-
(2009)
Journal of Clinical Pharmacology
, vol.49
, Issue.6
, pp. 650-660
-
-
Dahut, W.L.1
Aragon-Ching, J.B.2
Woo, S.3
-
66
-
-
70349234247
-
Phase i trial of docetaxel given every 3 weeks and daily lenalidomide in patients with advanced solid tumors
-
Sanborn S. L., Gibbons J., Krishnamurthi S., Phase I trial of docetaxel given every 3 weeks and daily lenalidomide in patients with advanced solid tumors Investigational New Drugs 2009 27 5 453 460
-
(2009)
Investigational New Drugs
, vol.27
, Issue.5
, pp. 453-460
-
-
Sanborn, S.L.1
Gibbons, J.2
Krishnamurthi, S.3
-
67
-
-
34248667282
-
Phase i trial of three-weekly docetaxel, carboplatin and oral lenalidomide (Revlimid) in patients with advanced solid tumors
-
Kalmadi S., Davis M., Dowlati A., Phase I trial of three-weekly docetaxel, carboplatin and oral lenalidomide (Revlimid) in patients with advanced solid tumors Investigational New Drugs 2007 25 3 211 216
-
(2007)
Investigational New Drugs
, vol.25
, Issue.3
, pp. 211-216
-
-
Kalmadi, S.1
Davis, M.2
Dowlati, A.3
-
68
-
-
0033764170
-
Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13)
-
Curnis F., Sacchi A., Borgna L., Magni F., Gasparri A., Corti A., Enhancement of tumor necrosis factor alpha antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13) Nature Biotechnology 2000 18 11 1185 1190
-
(2000)
Nature Biotechnology
, vol.18
, Issue.11
, pp. 1185-1190
-
-
Curnis, F.1
Sacchi, A.2
Borgna, L.3
Magni, F.4
Gasparri, A.5
Corti, A.6
-
69
-
-
0036468937
-
Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells
-
Curnis F., Arrigoni G., Sacchi A., Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells Cancer Research 2002 62 3 867 874
-
(2002)
Cancer Research
, vol.62
, Issue.3
, pp. 867-874
-
-
Curnis, F.1
Arrigoni, G.2
Sacchi, A.3
-
70
-
-
33644501437
-
Immunogenic and structural properties of the Asn-Gly-Arg (NGR) tumor neovasculature-homing motif
-
Di Matteo P., Curnis F., Longhi R., Immunogenic and structural properties of the Asn-Gly-Arg (NGR) tumor neovasculature-homing motif Molecular Immunology 2006 43 10 1509 1518
-
(2006)
Molecular Immunology
, vol.43
, Issue.10
, pp. 1509-1518
-
-
Di Matteo, P.1
Curnis, F.2
Longhi, R.3
-
71
-
-
0036678474
-
Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration
-
Curnis F., Sacchi A., Corti A., Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration Journal of Clinical Investigation 2002 110 4 475 482
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.4
, pp. 475-482
-
-
Curnis, F.1
Sacchi, A.2
Corti, A.3
-
72
-
-
14944353793
-
Tumor vascular targeting with tumor necrosis factor alpha and chemotherapeutic drugs
-
Corti A., Ponzoni M., Tumor vascular targeting with tumor necrosis factor alpha and chemotherapeutic drugs Annals of the New York Academy of Sciences 2004 1028 104 112
-
(2004)
Annals of the New York Academy of Sciences
, vol.1028
, pp. 104-112
-
-
Corti, A.1
Ponzoni, M.2
-
73
-
-
31544436380
-
Synergistic antitumor activity of cisplatin, paclitaxel, and gemcitabine with tumor vasculature-targeted tumor necrosis factor-alpha
-
Sacchi A., Gasparri A., Gallo-Stampino C., Toma S., Curnis F., Corti A., Synergistic antitumor activity of cisplatin, paclitaxel, and gemcitabine with tumor vasculature-targeted tumor necrosis factor-alpha Clinical Cancer Research 2006 12 1 175 182
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.1
, pp. 175-182
-
-
Sacchi, A.1
Gasparri, A.2
Gallo-Stampino, C.3
Toma, S.4
Curnis, F.5
Corti, A.6
-
74
-
-
33646407812
-
Targeted delivery of tumor necrosis factor-alpha to tumor vessels induces a therapeutic T cell-mediated immune response that protects the host against syngeneic tumors of different histologic origin
-
Balza E. L., Mortara L., Sassi F., Targeted delivery of tumor necrosis factor-alpha to tumor vessels induces a therapeutic T cell-mediated immune response that protects the host against syngeneic tumors of different histologic origin Clinical Cancer Research 2006 12 8 2575 2582
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.8
, pp. 2575-2582
-
-
Balza, E.L.1
Mortara, L.2
Sassi, F.3
-
75
-
-
0023225930
-
Characterization of the antitumor activities of human tumor necrosis factor-alpha and the comparison with other cytokines: Induction of tumor-specific immunity
-
Palladino M. A., Shalaby M. R., Kramer S. M., Characterization of the antitumor activities of human tumor necrosis factor-alpha and the comparison with other cytokines: induction of tumor-specific immunity Journal of Immunology 1987 138 11 4023 4032
-
(1987)
Journal of Immunology
, vol.138
, Issue.11
, pp. 4023-4032
-
-
Palladino, M.A.1
Shalaby, M.R.2
Kramer, S.M.3
-
76
-
-
42749085280
-
Vascular targeting, chemotherapy and active immunotherapy: Teaming up to attack cancer
-
Bellone M., Mondino A., Corti A., Vascular targeting, chemotherapy and active immunotherapy: teaming up to attack cancer Trends in Immunology 2008 29 5 235 241
-
(2008)
Trends in Immunology
, vol.29
, Issue.5
, pp. 235-241
-
-
Bellone, M.1
Mondino, A.2
Corti, A.3
-
77
-
-
77954645574
-
Phase II study of NGR-HTNF, a novel vascular targeting agent in colorectal cancer patients refractory to standard regimens
-
supplement 9 abstract no. H16, ix77
-
Bennicelli E., Santoro A., Rimassa L., Phase II study of NGR-HTNF, a novel vascular targeting agent in colorectal cancer patients refractory to standard regimens Annals of Oncology 2008 19 supplement 9. abstract no. H16, ix77
-
(2008)
Annals of Oncology
, vol.19
-
-
Bennicelli, E.1
Santoro, A.2
Rimassa, L.3
-
78
-
-
75749113143
-
Safety and antitumor activity of NGR-HTNF, a selective vascular targeting agent, administered at low dose in pretreated patients with hepatocellular carcinoma: Preliminary results of a phase II trial
-
supplement 8 abstract no. 546P, viii178
-
Citterio G., Santoro A., Pressiani T., Safety and antitumor activity of NGR-HTNF, a selective vascular targeting agent, administered at low dose in pretreated patients with hepatocellular carcinoma: preliminary results of a phase II trial Annals of Oncology 2008 19 supplement 8. abstract no. 546P, viii178
-
(2008)
Annals of Oncology
, vol.19
-
-
Citterio, G.1
Santoro, A.2
Pressiani, T.3
-
79
-
-
77954644234
-
Phase II trial of NGR-HTNF, a novel vascular targeting agent, in malignant pleural mesothelioma
-
supplement 9 abstract no. F8, ix57
-
Gregorc V., Zucali P., Ceresoli G., Phase II trial of NGR-HTNF, a novel vascular targeting agent, in malignant pleural mesothelioma Annals of Oncology 2008 19 supplement 9. abstract no. F8, ix57
-
(2008)
Annals of Oncology
, vol.19
-
-
Gregorc, V.1
Zucali, P.2
Ceresoli, G.3
-
80
-
-
67349221282
-
Phase i and DCE-MRI evaluation of NGR-TNF, a novel vascular targeting agent, in patients with solid tumors (EORTC 16041)
-
supplement abstract no. 3521
-
van Laarhoven H., Fiedler W., Desar I. M., Phase I and DCE-MRI evaluation of NGR-TNF, a novel vascular targeting agent, in patients with solid tumors (EORTC 16041) Journal of Clinical Oncology 2008 26 supplement. abstract no. 3521
-
(2008)
Journal of Clinical Oncology
, vol.26
-
-
Van Laarhoven, H.1
Fiedler, W.2
Desar, I.M.3
|