In vivo validation of MRI vessel caliber index measurement methods with intravital optical microscopy in a U87 mouse brain tumor model

Neuro-Oncology

Volumn 12, Issue 4, 2010, Pages 341-350

  Farrar, Christian T ^a   Kamoun, Walid S ^a   Ley, Carsten D ^a   Kim, Young R ^a   Kwon, Seon J ^a   Dai, Guangping ^a   Rosen, Bruce R ^a   Di Tomaso, Emmanuelle ^a   Jain, Rakesh K ^a   Sorensen, A Gregory ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Brain tumor; Intravital microscopy; Mouse; MRI; Tumor angiogenesis; Vessel caliber index

Indexed keywords

BIOLOGICAL MARKER; TETRAMETHYLRHODAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL DIAMETER; BRAIN BLOOD VESSEL; CELL STRAIN; CELL STRAIN U 87; CONTRAST ENHANCEMENT; CONTROLLED STUDY; CORRELATION ANALYSIS; GLIOMA; HISTOPATHOLOGY; HUMAN; HUMAN CELL; INTRAVITAL OPTICAL MICROSCOPY; MATHEMATICAL MODEL; MICROSCOPY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; STEADY STATE; TUMOR VOLUME; VALIDATION STUDY; ANIMAL; BRAIN TUMOR; DISEASE MODEL; METHODOLOGY; MULTIPHOTON MICROSCOPY; NEOVASCULARIZATION (PATHOLOGY); NUDE MOUSE; PATHOLOGY; TUMOR CELL CULTURE; VASCULARIZATION;

ANIMALS; BRAIN NEOPLASMS; DISEASE MODELS, ANIMAL; GLIOMA; HUMANS; MAGNETIC RESONANCE IMAGING; MICE; MICE, NUDE; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; MICROSCOPY, VIDEO; NEOVASCULARIZATION, PATHOLOGIC; TUMOR CELLS, CULTURED;

EID: 77954644423     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/nop032     Document Type: Article

References (36)

1. Dennie J, Mandeville JB, Boxerman JL, Packard SD, Rosen BR,Weisskoff RM. NMR imaging of changes in vascular morphology due to tumor angiogenesis. Magn Reson Med. 1998;40:793-799.
2. Badruddoja MA, Krouwer HGJ, Rand SD, Rebro KJ, Pathak AP, Schmainda KM. Antiangiogenic effects of dexamethasone in 9L gliosarcoma assesed by MRI cerebral blood volume maps. Neuro-Oncology. 2003;5:235-243.
3. Packard SD, Mandeville JB, Ichikawa T, et al. Functional response of tumor vasculature to PaCO2: determination of total and microvascular blood volume by MRI. Neoplasia. 2003;5(4):330-338.
4. Tropres I, Lamalle L, Peoc'h M, et al. In vivo assesment of tumoral angiogenesis. Magn Reson Med. 2004;51:533-541.
5. Kiselev VG, Strecker R, Ziyeh S, Speck O, Hennig J. Vessel size imaging in humans. Magn Reson Med. 2005;53(3):553-563.
6. Batchelor TT, Sorensen AG, Tomaso Ed, et al. AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell. 2007;11:83-95.
7. Valable S, Lemasson B, Farion R, et al. Assessment of blood volume, vessel size, and the expression of angiogenic factors in two rat glioma models: a longitudinal in vivo and ex vivo study. NMR Biomed. 2008;21(10):1043-1056.
8. Weisskoff RM, Zuo CS, Boxerman JL, Rosen BR. Microscopic susceptibility variation and transverse relaxation: theory and experiment. Magn Reson Med. 1994;31:601-610.
9. Boxerman JL, Hamberg LM, Rosen BR, Weisskoff RM. MR contrast due to intravascular magnetic susceptibility perturbations. Magn Reson Med. 1995;34:555-566.
10. Pathak AP, Ward BD, Schmainda KM. A novel technique for modeling susceptibility-based contrast mechanisms for arbitrary microvascular geometries: the finite perturber method. Neuroimage. 2008;40(3):1130-1143.
11. Pathak AP, Rand SD, Schmainda KM. The effect of brain tumor angiogenesis on the in vivo relationship between the gradient-echo relaxation rate change (ΔR2*) and contrast agent (MION) dose. J Magn Reson Imaging. 2003;18(4):397-403.
12. Tropres I, Grimault S, Vaeth A, et al. Vessel size imaging. Magn Reson Med. 2001;45:397-408.
13. Mandeville JB, Leita FP, Marota JJA. Spin-echo MRI underestimates functional changes in microvascular cerebral blood plasma volume using exogenous contrast agent. Magn Reson Med. 2007;58:769-776.
14. Aronen HJ, Cohen MS, Belliveau JW, Fordham JA, Rosen BR. Ultrafast imaging of brain tumors. Top Magn Reson Imaging. 1993;5(1):14-24.
15. Maeda M, Itoh S, Kimura H, et al. Tumor vascularity in the brain: evaluation with dynamic susceptibility-contrast MR imaging. Radiology. 1993;189(1):233-238.
16. Aronen HJ, Gazit IE, Louis DN, et al. Cerebral blood volume maps of gliomas: comparison with tumor grade and histologic findings. Radiology. 1994;191(1):41-51.
17. Siegal T, Rubinstein R, Tzuk-Shina T, Gomori JM. Utility of relative cerebral blood volume mapping derived from perfusion magnetic resonance imaging in the routine follow up of brain tumors. J Neurosurg. 1997;86(1):22-27.
18. Donahue KM, Krouwer HGJ, Rand SD, et al. Utility of simultaneously acquired gradient-echo and spin-echo cerebral blood volume and morphology maps in brain tumor patients. Magn Reson Med. 2000;43:845-853.
19. Vonken EP, van Osch MJ, Bakker CJ, Viergever MA. Simultaneous quantitative cerebral perfusion and Gd-DTPA extravasation measurement with dual-echo dynamic susceptibility contrast MRI. Magn Reson Med. 2000;43(6):820-827.
20. Schmainda KM, Rand SD, Joseph AM, et al. Characterization of a firstpass gradient-echo spin-echo method to predict brain tumor grade and angiogenesis. Am J Neuroradiol. 2004;25:1524-1532.
21. Quarles CC, Ward BD, Schmainda KM. Improving the reliability of obtaining tumor hemodynamic parameters in the presence of contrast agent extravasation. Magn Reson Med. 2005;53(6):1307-1316.
22. Boxerman JL, Schmainda KM, Weisskoff RM. Relative cerebral blood volume maps corrected for contrast agent extravasation significantly correlate with glioma tumor grade, whereas uncorrected maps do not. Am J Neuroradiol. 2006;27:859-867.
23. Yuan F, Salehi HA, Boucher Y, Vasthare US, Tuma RF, Jain RK. Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows. Cancer Res. 1994;54(17):4564-4568.
24. Jain RK, Munn LL, Fukumura D. Dissecting tumour pathophysiology using intravital microscopy. Nat Rev Cancer. 2002;2(4):266-276.
25. Tyrrell JA, di Tomaso E, Fuja D, et al. Robust 3-D modeling of vasculature imagery using superellipsoids. IEEE Trans Med Imaging. 2007;26(2):223-237.
26. Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature. 2000;407(6801):249-257.
27. Brown EB, Campbell RB, Tsuzuki Y, et al. In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy. Nat Med. 2001;7(7):864-868.
28. Jain RK, di Tomaso E, Duda DG, Loeffler JS, Sorensen AG, Batchelor TT. Angiogenesis in brain tumours. Nat Rev Neurosci. 2007;8(8):610-622.
29. Leon SP, Folkerth RD, Black PM. Microvessel density is a prognostic indicator for patients with astroglial brain tumors. Cancer. 1996;77(2):362-372.
30. Weidner N, Folkman J. Tumoral vascularity as a prognostic factor in cancer. Important Adv Oncol. 1996:167-190.
31. Folkman J. Seminars in medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis. N Engl J Med. 1995;333(26):1757-1763.
32. Delorme S, Knopp MV. Non-invasive vascular imaging: assessing tumour vascularity. Eur Radiol. 1998;8(4):517-527.
33. Kamoun WS, Ley CD, Farrar CT, et al. Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice. J Clin Oncol. 2009;27(15):2542-2552.
34. Yablonskiy DA, Haacke EM. Theory of NMR signal behavior in magnetically inhomogeneous tissues: the static dephasing regime. Magn Reson Med. 1994;32(6):749-763.
35. Rohrer M, Bauer H, Mintorovitch J, Requardt M, Weinmann HJ. Comparison of magnetic properties of MRI contrast media solutions at different magnetic field strengths. Invest Radiol. 2005;40(11):715-724.
36. Pannetier N, Lemasson B, Christen T, et al. Vessel size imaging with iron oxide and with gadolinium: a comparative study in rodent. Proc Intl Soc Mag Reson Med. 2009;17:748.