Simultaneous quantitative cerebral perfusion and Gd-DTPA extravasation measurement with dual-echo dynamic susceptibility contrast MRI

Magnetic Resonance in Medicine

Volumn 43, Issue 6, 2000, Pages 820-827

  Vonken, Evert Jan Ph A ^a,b   Van Osch, Matthias J P ^a   Bakker, Chris J G ^a   Viergever, Max A ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b Department of Cell Biology   (Netherlands)

Author keywords

Cerebral blood flow (CBF); Cerebral blood volume (CBV); Dynamic susceptibility contrast magnetic resonance imaging (DSC MRI); Perfusion

Indexed keywords

BRAIN; HEMODYNAMICS; MAGNETIC RESONANCE IMAGING; MAGNETIC SUSCEPTIBILITY; RATE CONSTANTS; SIGNAL TO NOISE RATIO; TISSUE;

CEREBRAL BLOOD FLOW; CEREBRAL BLOOD VOLUME(CBV); DYNAMIC SUSCEPTIBILITY CONTRAST MAGNETIC RESONANCE IMAGING; DYNAMIC SUSCEPTIBILITY CONTRAST MRIS; GLIOBLASTOMA MULTIFORME; LOW SIGNAL-TO-NOISE RATIO; PERFUSION; PERFUSION QUANTIFICATION;

BLOOD;

GADOLINIUM PENTETATE;

ADULT; ARTICLE; BLOOD BRAIN BARRIER; BLOOD VOLUME; BRAIN PERFUSION; CASE REPORT; COMPARTMENT MODEL; CONTRAST ENHANCEMENT; GLIOBLASTOMA; HEMODYNAMIC MONITORING; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MATHEMATICAL COMPUTING; NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE DIAGNOSIS; SIMULATION;

EID: 0034080073     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/1522-2594(200006)43:6<820::AID-MRM7>3.0.CO;2-F     Document Type: Article

References (27)

1. Griebel J, Mayr NA, de Vries A, Knopp MV, Gneiting T, Kremser C, Essig M, Hawighorst H, Lukas PH, Yuh WTC. Assessment of tumor microcirculation: a new role of dynamic contrast MR imaging. J Magn Reson Imaging 1997;7:111-119.
2. Rempp KA, Brix G, Wenz F, Becker CR, Gückel F, Lorenz WJ. Quantification of regional cerebral blood flow and volume with dynamic susceptibility contrast-enhanced MR imaging. Radiology 1994;193: 637-641.
3. Østergaard L, Sorensen AG, Kwong KK, Weisskoff RM, Gyldensted C, Rosen BR. High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part II: experimental comparison and preliminary results. Magn Reson Med 1996;36:726-736.
4. Zierler KL. Circulation times and the theory of indicator-dilution methods for determining blood flow and volume. In: Handbook of physiology. Baltimore: Williams & Wilkins; 1962. p 585-615.
5. Aronen HJ, Gazit IE, Louis DN, Buchbinder BR, Pardo FS, Weiskoff RM, Harsh GR, Cosgrove GR, Halpern EF, Hochberg FH, Rosen BR. Cerebral blood volume maps of gliomas: comparison with tumor grade and histologic findings. Radiology 1994;191:41-51.
6. Heiland S, Banner T, Debus J, Rempp K, Reith W, Sartor K. Simultaneous assessment of cerebral hemodynamics and contrast agent uptake in lesions with disrupted blood-brain-barrier. Magn Reson Imaging 1999;17:21-27.
7. Østergaard L, Hochberg FH, Rabinov JD, Sorensen AG, Lev M, Kim L, Weisskoff RM, Gonzalez RG, Gyldensted C, Rosen BR. Early changes measured by magnetic resonance imaging in cerebral blood flow, blood volume, and blood-brain barrier permeability following dexamethasone treatment in patients with brain tumors. J Neurosurg 1999;90:300-305.
8. Li TQ, Østergaard L, Skejö P. Simultaneous blood flow, blood volume and permeability mapping using dual-echo spiral imaging: methodology and initial validatin with spiral-FAIR. In: Proceedings of the 6th Annual Meeting of ISMRM, Sydney, Australia, 1998. p 1189.
9. Kovar DA, Lewis MZ, River JN, Lipton MJ, Karczmar GS. In Vivo imaging of extraction fraction of low molecular weight MR contrast agents and perfusion rate in rodent tumors. Magn Reson Med 1997;38: 259-268.
10. Kovar DA, Lewis M, Karczmar GS. A new method for imaging perfusion and contrast extraction fraction: input functions derived from reference tissue. J Magn Reson Imaging 1998;8:1126-1134.
11. Su MY, Müller A, Lao X, Nalcioglu O. Tumor characterization with dynamic contrast-enhanced MRI using MR contrast agents of various molecular weights. Magn Reson Med 1998;39:259-269.
12. Meier P, Zierler KL. On the theory of the indicator-dilution method for measurement of blood flow and volume. J Appl Physiol 1954;6:731-744.
13. Boxerman JL, Hamberg LM, Rosen BR, Weisskoff RM. MR contrast due to intravascular magnetic susceptibility perturbations. Magn Reson Med 1995;34:555-566.
14. Tofts PS. Modeling tracer kinetics in dynamic Gd-DTPA MR imaging. J Magn Reson Imaging 1997;7:91-101.
15. Donahue KM, Burstein D, Manning WJ, Gray ML. Studies of Gd-DTPA relaxivity and proton exchange rates in tissue. Magn Reson Med 1994; 32:66-76.
16. Parker GJM, Suckling J, Tanner SF, Padhani AR, Revell PB, Husband JE, Leach MO. Probing tumor microvascularity by measurement, analysis and display of contrast agent uptake kinetics. J Magn Reson Imaging 1997;7:564-574.
17. Østergaard L, Weisskoff RM, Chesler DA, Gyldensted C, Rosen BR. High resolution measurements of cerebral blood flow using intravascular tracer bolus passages. Part I: mathematical approach and statistical analysis. Magn Reson Med 1996;36:715-725.
18. Weisskoff RM, Chesler D, Boxerman JL, Rosen BR. Pitfalls in MR measurements of tissue blood flow with intravascular tracers: which mean transit time? Magn Reson Med 1993;29:553-559.
19. Vonken EPA, Beekman FJ, Bakker CJG, Viergever MA. Maximum likelihood estimation of cerebral blood flow in dynamic susceptibility contrast MRI. Magn Reson Med 1999;41:343-350.
20. Kreyszig E. Advanced engineering mathematics. 7th edition. New York: John Wiley & Sons; 1993.
21. Mineura K, Sasjima T, Itoh Y, Sasajima H, Kowada M, Tomura N, Uesaka Y, Ogawa T, Hatazawa J, Uemura K. Blood flow and metabolism of central neurocytoma. Cancer 1995;76:1224-1232.
22. Zünkeler B, Carson RE, Olson J, Blasberg RG, DeVroom H, Lutz RJ, Saris SC, Wright DC, Kammerer W, Patronas NJ, Dedrick RL, Herscovitch P, Oldfield EH. Quantification and pharmacokinetics of blood-brain barrier disruption in humans. J Neurosurg 1996;85: 1056-1065.
23. Hamberg LM, Boccalini P, Stranjalis G, Hunter GJ, Huang Z, Halpern E, Weisskoff RM, Moskowitz MA, Rosen BR. Continuous assessment of relative cerebral blood volume in transient ischemia using steady state susceptibility-contrast MRI. Magn Reson Med 1996;35:168-173.
24. Brix G, Semmler W, Port R, Schad LR, Layer G, Lorenz WJ. Pharmacokinetic parameters in CNS Gd-DTPA enhanced MR imaging. J Comput Assist Tomogr 1991;15:621-628.
25. Vonken EPA, van Osch MJP, Bakker CJG, Viergever MA. Measurement of cerebral perfusion with dual echo multi-slice quantitative dynamic-susceptibility contrast mri. J Magn Reson Imaging 1999;10: 109-117.
26. Simonsen CZ, Østergaard L, Smith DF, Vestergaard-Poulsen P, Gyldensted C. Gradient echoes or spin echoes for CBF, CBV, and MTT measurements? In: Proceedings of the 7th Annual Meeting of ISMRM, Philadelphia, 1999. p 606.
27. Sugahara T, Korogi Y, Kochi M, Hirai T, Okuda T, Shigematsu Y, Liang L, Ge Y, Ushio Y, Takahashi M. Correlation of MR Imaging-determined cerebral blood volume maps with histologic and angiographic: determination of vascularity of gliomas. Am J Röntgen 1998; 171:1479-1486.