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Volumn 57, Issue 3, 2010, Pages 228-233

Transcriptional inactivation of secreted frizzled-related protein 1 by promoter hypermethylation as a potential biomarker for non-small cell lung cancer

Author keywords

Biomarker; DNA methylation; Non small cell lung cancer; SFRP 1

Indexed keywords

ANTINEOPLASTIC AGENT; SECRETED FRIZZLED RELATED PROTEIN 1; SECRETED FRIZZLED RELATED PROTEIN 2; SECRETED FRIZZLED RELATED PROTEIN 4; SECRETED FRIZZLED RELATED PROTEIN 5; MEMBRANE PROTEIN; MESSENGER RNA; SFRP1 PROTEIN, HUMAN; SIGNAL PEPTIDE; TUMOR MARKER;

EID: 77954636165     PISSN: 00282685     EISSN: None     Source Type: Journal    
DOI: 10.4149/neo_2010_03_228     Document Type: Article
Times cited : (37)

References (36)
  • 1
  • 2
    • 33750315764 scopus 로고    scopus 로고
    • Survival of patients with stage I lung cancer detected on CT screening
    • doi:10.1056/NEJMoa060476
    • HENSCHKE CI, YANKELEVITZ DF, LIBBY DM, PASMANTIER MW, SMITH JP et al.: Survival of patients with stage I lung cancer detected on CT screening. N Engl J Med 2006; 355: 1763-1771. doi:10.1056/NEJMoa060476
    • (2006) N Engl J Med , vol.355 , pp. 1763-1771
    • Henschke, C.I.1    Yankelevitz, D.F.2    Libby, D.M.3    Pasmantier, M.W.4    Smith, J.P.5
  • 3
    • 56849133040 scopus 로고    scopus 로고
    • DNA methylation-based biomarkers for early detection of non-small cell lung cancer: An update
    • doi:101186/1476-4598-7-81
    • ANGLIM PP, ALONZO TA, LAIRD-OFFRINGA IA: DNA methylation-based biomarkers for early detection of non-small cell lung cancer: an update. Mol Cancer 2008; 7: 81. doi:10.1186/1476-4598-7-81
    • (2008) Mol Cancer , vol.7 , pp. 81
    • Anglim, P.P.1    Alonzo, T.A.2    Laird-Offringa, I.A.3
  • 4
    • 25144438960 scopus 로고    scopus 로고
    • Gene promoter methylation in plasma and sputum increases with lung cancer risk
    • doi:10.1158/1078-0432.CCR-05-0625
    • BELINSKY SA, KLINGE DM, DEKKER JD, SMITH MW, BOCKLAGE TJ et al.: Gene promoter methylation in plasma and sputum increases with lung cancer risk. Clin Cancer Res 2005; 11: 6505-6511. doi:10.1158/1078-0432.CCR-05-0625
    • (2005) Clin Cancer Res , vol.11 , pp. 6505-6511
    • Belinsky, S.A.1    Klinge, D.M.2    Dekker, J.D.3    Smith, M.W.4    Bocklage, T.J.5
  • 5
    • 2942737264 scopus 로고    scopus 로고
    • Tumor-specific methylation in bronchial lavage for the early detection of non-small-cell lung cancer
    • doi:10.1200/JCO.2004.10.077
    • KIM H, KWON YM, KIM JS, LEE H, PARK JH et al.: Tumor-specific methylation in bronchial lavage for the early detection of non-small-cell lung cancer. J Clin Oncol 2004; 22: 2363-2370. doi:10.1200/JCO.2004.10.077
    • (2004) J Clin Oncol , vol.22 , pp. 2363-2370
    • Kim, H.1    Kwon, Y.M.2    Kim, J.S.3    Lee, H.4    Park, J.H.5
  • 6
    • 17444419037 scopus 로고    scopus 로고
    • Wnt signaling in lung cancer
    • doi:10.1016/j.canlet.2004.08.040
    • MAZIERES J, HE B, YOU L, XU Z, JABLONS DM.: Wnt signaling in lung cancer. Cancer Lett 2005; 222: 1-10. doi:10.1016/j.canlet.2004.08.040
    • (2005) Cancer Lett , vol.222 , pp. 1-10
    • Mazieres, J.1    He, B.2    You, L.3    Xu, Z.4    Jablons, D.M.5
  • 7
    • 34447521472 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer
    • doi:10.1038/ sj.onc.1210259
    • NOJIMA M, SUZUKI H, TOYOTA M, WATANABE Y, MARUYAMA R et al.: Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer. Oncogene 2007; 26: 4699-4713. doi:10.1038/ sj.onc.1210259
    • (2007) Oncogene , vol.26 , pp. 4699-4713
    • Nojima, M.1    Suzuki, H.2    Toyota, M.3    Watanabe, Y.4    Maruyama, R.5
  • 8
    • 46949109354 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma
    • doi:10.1007/s00535-008-2170-0
    • TAKAGI H, SASAKI S, SUZUKI H, TOYOTA M, MARUYAMA R et al.: Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma. J Gastroenterol 2008; 43: 378-389. doi:10.1007/s00535-008-2170-0
    • (2008) J Gastroenterol , vol.43 , pp. 378-389
    • Takagi, H.1    Sasaki, S.2    Suzuki, H.3    Toyota, M.4    Maruyama, R.5
  • 9
    • 23244461593 scopus 로고    scopus 로고
    • Aberrant methylation of secreted frizzled-related protein genes in esophageal adenocarcinoma and Barrett's esophagus
    • doi:10.1002/ijc.21045
    • ZOU H, MOLINA JR, HARRINGTON JJ, OSBORN NK, KLATT KK et al.: Aberrant methylation of secreted frizzled-related protein genes in esophageal adenocarcinoma and Barrett's esophagus. Int J Cancer 2005; 116: 584-591. doi:10.1002/ijc.21045
    • (2005) Int J Cancer , vol.116 , pp. 584-591
    • Zou, H.1    Molina, J.R.2    Harrington, J.J.3    Osborn, N.K.4    Klatt, K.K.5
  • 10
    • 40849116461 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer
    • doi:10.1038/sj.bjc.6604259
    • SUZUKI H, TOYOTA M, CARAWAY H, GABRIELSON E, OHMURA T et al.: Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer. Br J Cancer 2008; 98: 1147-1156. doi:10.1038/sj.bjc.6604259
    • (2008) Br J Cancer , vol.98 , pp. 1147-1156
    • Suzuki, H.1    Toyota, M.2    Caraway, H.3    Gabrielson, E.4    Ohmura, T.5
  • 11
    • 34147190412 scopus 로고    scopus 로고
    • Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia
    • doi:10.1182/blood-2006-09-047043
    • ROMAN-GOMEZ J, CORDEU L, AGIRRE X, JIMENEZ-VELASCO A, SAN JOSE-ENERIZ E et al.: Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia. Blood 2007; 109: 3462-3469. doi:10.1182/blood-2006-09-047043
    • (2007) Blood , vol.109 , pp. 3462-3469
    • Roman-Gomez, J.1    Cordeu, L.2    Agirre, X.3    Jimenez-Velasco, A.4    San Jose-Eneriz, E.5
  • 12
    • 35948990450 scopus 로고    scopus 로고
    • Synchronous alterations of Wnt and epidermal growth factor receptor signaling pathways through aberrant methylation and mutation in non small cell lung cancer
    • doi:10.1158/ 1078-0432.CCR-07-0591
    • SUZUKI M, SHIGEMATSU H, NAKAJIMA T, KUBO R, MOTOHASHI S et al.: Synchronous alterations of Wnt and epidermal growth factor receptor signaling pathways through aberrant methylation and mutation in non small cell lung cancer. Clin Cancer Res 2007; 13: 6087-6092. doi:10.1158/ 1078-0432.CCR-07-0591
    • (2007) Clin Cancer Res , vol.13 , pp. 6087-6092
    • Suzuki, M.1    Shigematsu, H.2    Nakajima, T.3    Kubo, R.4    Motohashi, S.5
  • 13
    • 33751275546 scopus 로고    scopus 로고
    • Examination of a CpG island methylator phenotype and implications of methylation profiles in solid tumors
    • doi:10.1158/ 0008-5472.CAN-06-1687
    • MARIST CJ, HOUSEMAN EA, CHRISTENSEN BC, EDDY K, BUENO R et al.: Examination of a CpG island methylator phenotype and implications of methylation profiles in solid tumors. Cancer Res 2006; 66: 10621-10629. doi:10.1158/ 0008-5472.CAN-06-1687
    • (2006) Cancer Res , vol.66 , pp. 10621-10629
    • Marist, C.J.1    Houseman, E.A.2    Christensen, B.C.3    Eddy, K.4    Bueno, R.5
  • 14
    • 0036613250 scopus 로고    scopus 로고
    • A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
    • doi:10.1038/ng892
    • SUZUKI H, GABRIELSON E, CHEN W, ANBAZHAGAN R, VAN ENGELAND M et al.: A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. Nat Genet 2002; 31: 141-149. doi:10.1038/ng892
    • (2002) Nat Genet , vol.31 , pp. 141-149
    • Suzuki, H.1    Gabrielson, E.2    Chen, W.3    Anbazhagan, R.4    van Engeland, M.5
  • 15
    • 33646247418 scopus 로고    scopus 로고
    • Combination analysis of hypermethylated Wnt-antagonist family genes as a novel epigenetic biomarker panel for bladder cancer detection
    • doi:10.1158/1078-0432.CCR-05-2468
    • URAKAMI S, SHIINA H, ENOKIDA H, KAWAKAMI T, KAWAMOTO K et al.: Combination analysis of hypermethylated Wnt-antagonist family genes as a novel epigenetic biomarker panel for bladder cancer detection. Clin Cancer Res 2006; 12: 2109-2116. doi:10.1158/1078-0432.CCR-05-2468
    • (2006) Clin Cancer Res , vol.12 , pp. 2109-2116
    • Urakami, S.1    Shiina, H.2    Enokida, H.3    Kawakami, T.4    Kawamoto, K.5
  • 16
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT, Method
    • doi:10.1006/ meth.20011262
    • LIVAK KJ, SCHMITTGEN TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT Method. Methods 2001; 25: 402-408. doi:10.1006/ meth.2001.1262
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 17
    • 34548455905 scopus 로고    scopus 로고
    • Roles of secreted frizzled-related proteins in cancer
    • doi:10.1111/j.1745-7254.2007.00692x
    • SHI Y, HE B, YOU L, JABLONS DM: Roles of secreted frizzled-related proteins in cancer. Acta Pharmacol Sin 2007; 28: 1499-1504. doi:10.1111/j.1745-7254.2007.00692.x
    • (2007) Acta Pharmacol Sin , vol.28 , pp. 1499-1504
    • Shi, Y.1    He, B.2    You, L.3    Jablons, D.M.4
  • 18
    • 0141995804 scopus 로고    scopus 로고
    • WIF1, a component of the Wnt pathway, is downregulated in prostate, breast, lung, and bladder cancer
    • doi:10.1002/path.1449
    • WISSMANN C, WILD PJ, KAISER S, ROEPCKE S, STOEHR R et al.: WIF1, a component of the Wnt pathway, is downregulated in prostate, breast, lung, and bladder cancer. J Pathol 2003; 201: 204-212. doi:10.1002/path.1449
    • (2003) J Pathol , vol.201 , pp. 204-212
    • Wissmann, C.1    Wild, P.J.2    Kaiser, S.3    Roepcke, S.4    Stoehr, R.5
  • 19
    • 4544249671 scopus 로고    scopus 로고
    • Inverse correlation of secreted frizzledrelated protein 4 and beta-catenin expression in endometrial stromal sarcomas
    • doi:10.1002/path.1616
    • HRZENJAK A, TIPPL M, KREMSER ML, STROHMEIER B, GUELLY C et al.: Inverse correlation of secreted frizzledrelated protein 4 and beta-catenin expression in endometrial stromal sarcomas. J Pathol 2004; 204: 19-27. doi:10.1002/path.1616
    • (2004) J Pathol , vol.204 , pp. 19-27
    • Hrzenjak, A.1    Tippl, M.2    Kremser, M.L.3    Strohmeier, B.4    Guelly, C.5
  • 20
    • 28844506777 scopus 로고    scopus 로고
    • Expression of sFRP-4 and beta-catenin in human colorectal carcinoma
    • doi:10.1016/j.canlet.2005.01.026
    • FENG HAN Q, ZHAO W, BENTEL J, SHEARWOOD AM, ZEPS N et al.: Expression of sFRP-4 and beta-catenin in human colorectal carcinoma. Cancer Lett 2006; 231: 129-137. doi:10.1016/j.canlet.2005.01.026
    • (2006) Cancer Lett , vol.231 , pp. 129-137
    • Feng Han, Q.1    Zhao, W.2    Bentel, J.3    Shearwood, A.M.4    Zeps, N.5
  • 21
    • 33646385376 scopus 로고    scopus 로고
    • Epigenetic Suppression of Secreted Frizzled Related Protein 1 (SFRP1) Expression in Human Breast Cancer
    • LO PK, MEHROTRA J, D'COSTA A, FACKLER MJ, GARRETT-MAYER E et al.: Epigenetic Suppression of Secreted Frizzled Related Protein 1 (SFRP1) Expression in Human Breast Cancer. Cancer Biol Ther 2006; 5: 281-286.
    • (2006) Cancer Biol Ther , vol.5 , pp. 281-286
    • Lo, P.K.1    Mehrotra, J.2    D'Costa, A.3    Fackler, M.J.4    Garrett-Mayer, E.5
  • 22
    • 34547770885 scopus 로고    scopus 로고
    • Down-regulation of SFRP1 as a putative tumor suppressor gene can contribute to human hepatocellular carcinoma
    • doi:10.1186/1471-2407-7-126
    • HUANG J, ZHANG YL, TENG XM, LIN Y, ZHENG DL et al.: Down-regulation of SFRP1 as a putative tumor suppressor gene can contribute to human hepatocellular carcinoma. BMC Cancer 2007; 7: 126. doi:10.1186/1471-2407-7-126
    • (2007) BMC Cancer , vol.7 , pp. 126
    • Huang, J.1    Zhang, Y.L.2    Teng, X.M.3    Lin, Y.4    Zheng, D.L.5
  • 23
    • 58149354782 scopus 로고    scopus 로고
    • Methylation-associated silencing of SFRP1 in renal cell carcinoma
    • AWAKURA Y, NAKAMURA E, ITO N, KAMOTO T, OGAWA O: Methylation-associated silencing of SFRP1 in renal cell carcinoma. Oncol Rep 2008; 20: 1257-1263.
    • (2008) Oncol Rep , vol.20 , pp. 1257-1263
    • Awakura, Y.1    Nakamura, E.2    Ito, N.3    Kamoto, T.4    Ogawa, O.5
  • 24
    • 30544447981 scopus 로고    scopus 로고
    • Transcriptional silencing of secreted frizzled related protein 1 (SFRP 1) by promoter hypermethylation in nonsmall-cell lung cancer
    • doi:10.1038/ sj.onc.1208777
    • FUKUI T, KONDO M, ITO G, MAEDA O, SATO N et al.: Transcriptional silencing of secreted frizzled related protein 1 (SFRP 1) by promoter hypermethylation in nonsmall-cell lung cancer. Oncogene 2005; 24: 6323-6327. doi:10.1038/ sj.onc.1208777
    • (2005) Oncogene , vol.24 , pp. 6323-6327
    • Fukui, T.1    Kondo, M.2    Ito, G.3    Maeda, O.4    Sato, N.5
  • 25
    • 34547093863 scopus 로고    scopus 로고
    • SFRP1 suppressed hepatoma cells growth through Wnt canonical signaling pathway
    • doi:10.1002/ijc.22750
    • SHIH YL, HSIEH CB, LAI HC, YAN MD, HSIEH TY et al.: SFRP1 suppressed hepatoma cells growth through Wnt canonical signaling pathway. Int J Cancer 2007; 121: 1028-1035. doi:10.1002/ijc.22750
    • (2007) Int J Cancer , vol.121 , pp. 1028-1035
    • Shih, Y.L.1    Hsieh, C.B.2    Lai, H.C.3    Yan, M.D.4    Hsieh, T.Y.5
  • 26
    • 60749096511 scopus 로고    scopus 로고
    • SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway
    • doi:10.1016/ j.ygyno.2008.10.026
    • CHUNG MT, LAI HC, SYTWU HK, YAN MD, SHIH YL et al.: SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway. Gynecol Oncol 2009; 112: 646-653. doi:10.1016/ j.ygyno.2008.10.026
    • (2009) Gynecol Oncol , vol.112 , pp. 646-653
    • Chung, M.T.1    Lai, H.C.2    Sytwu, H.K.3    Yan, M.D.4    Shih, Y.L.5
  • 27
    • 47249111724 scopus 로고    scopus 로고
    • Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung
    • doi:10.1093/carcin/bgn017
    • LICCHESI JD, WESTRA WH, HOOKER CM, MACHIDA EO, BAYLIN SB et al.: Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung. Carcinogenesis 2008; 29: 895-904. doi:10.1093/carcin/bgn017
    • (2008) Carcinogenesis , vol.29 , pp. 895-904
    • Licchesi, J.D.1    Westra, W.H.2    Hooker, C.M.3    McHida, E.O.4    Baylin, S.B.5
  • 28
    • 0035866393 scopus 로고    scopus 로고
    • DNA fragments in the blood plasma of cancer patients: Quantitations and evidence for their origin from apoptotic and necrotic cells
    • JAHR S, HENTZE H, ENGLISCH S, HARDT D, FACKELMAYER FO et al.: DNA fragments in the blood plasma of cancer patients: Quantitations and evidence for their origin from apoptotic and necrotic cells. Cancer Res 2001; 61: 1659-1665.
    • (2001) Cancer Res , vol.61 , pp. 1659-1665
    • Jahr, S.1    Hentze, H.2    Englisch, S.3    Hardt, D.4    Fackelmayer, F.O.5
  • 29
    • 35648953334 scopus 로고    scopus 로고
    • Characterization of a multiple epigenetic marker panel for lung cancer detection and risk assessment in plasma
    • doi:10.1002/cncr.23001
    • HSU HS, CHEN TP, HUNG CH, WEN CK, LIN RK et al.: Characterization of a multiple epigenetic marker panel for lung cancer detection and risk assessment in plasma. Cancer 2007; 110: 2019-2026. doi:10.1002/cncr.23001
    • (2007) Cancer , vol.110 , pp. 2019-2026
    • Hsu, H.S.1    Chen, T.P.2    Hung, C.H.3    Wen, C.K.4    Lin, R.K.5
  • 30
    • 19944433956 scopus 로고    scopus 로고
    • Identification of epigenetic aberrant promoter methylation in serum DNA, is useful for early detection of lung cancer
    • FUJIWARA K, FUJIMOTO N, TABATA M, NISHII K, MATSUO K et al.: Identification of epigenetic aberrant promoter methylation in serum DNA is useful for early detection of lung cancer. Clin Cancer Res 2005; 11: 1219-1225.
    • (2005) Clin Cancer Res , vol.11 , pp. 1219-1225
    • Fujiwara, K.1    Fujimoto, N.2    Tabata, M.3    Nishii, K.4    Matsuo, K.5
  • 31
    • 34247217491 scopus 로고    scopus 로고
    • Predicting gene promoter methylation in non-small-cell lung cancer by evaluating sputum and serum
    • doi:10.1038/ sj.bjc.6603721
    • BELINSKY SA, GRIMES MJ, CASAS E, STIDLEY CA, FRANKLIN WA et al.: Predicting gene promoter methylation in non-small-cell lung cancer by evaluating sputum and serum. Br J Cancer 2007; 96: 1278-1283. doi:10.1038/ sj.bjc.6603721
    • (2007) Br J Cancer , vol.96 , pp. 1278-1283
    • Belinsky, S.A.1    Grimes, M.J.2    Casas, E.3    Stidley, C.A.4    Franklin, W.A.5
  • 32
    • 34247265566 scopus 로고    scopus 로고
    • Identification of epigenetic aberrant promoter methylation of RASSF1A in serum DNA and its clinicopathological significance in lung cancer
    • doi:10.1016/j.lungcan.2006.12.007
    • WANG Y, YU Z, WANG T, ZHANG J, HONG L et al.: Identification of epigenetic aberrant promoter methylation of RASSF1A in serum DNA and its clinicopathological significance in lung cancer. Lung Cancer 2007; 56: 289-294. doi:10.1016/j.lungcan.2006.12.007
    • (2007) Lung Cancer , vol.56 , pp. 289-294
    • Wang, Y.1    Yu, Z.2    Wang, T.3    Zhang, J.4    Hong, L.5
  • 33
    • 33745026527 scopus 로고    scopus 로고
    • Aberrant methylation of the Wnt antagonist SFRP1 in breast cancer is associated with unfavourable prognosis
    • doi:10.1038/ sj.onc.1209386
    • VEECK J, NIEDERACHER D, AN H, KLOPOCKI E, WIESMANN F et al.: Aberrant methylation of the Wnt antagonist SFRP1 in breast cancer is associated with unfavourable prognosis. Oncogene 2006; 25: 3479-3488. doi:10.1038/ sj.onc.1209386
    • (2006) Oncogene , vol.25 , pp. 3479-3488
    • Veeck, J.1    Niederacher, D.2    An, H.3    Klopocki, E.4    Wiesmann, F.5
  • 34
    • 65349187055 scopus 로고    scopus 로고
    • Cancer epigenomics: Implications of DNA methylation in personalized cancer therapy
    • doi:10.1111/j.1349-7006.2009.01095.x
    • TOYOTA M, SUZUKI H, YAMASHITA T, HIRATA K, IMAI K et al.: Cancer epigenomics: implications of DNA methylation in personalized cancer therapy. Cancer Sci 2009; 100: 787-791. doi:10.1111/j.1349-7006.2009.01095.x
    • (2009) Cancer Sci , vol.100 , pp. 787-791
    • Toyota, M.1    Suzuki, H.2    Yamashita, T.3    Hirata, K.4    Imai, K.5
  • 35
    • 41149143617 scopus 로고    scopus 로고
    • Multiple gene methylation of nonsmall cell lung cancers evaluated with 3-dimensional microarray
    • doi:10.1002/cncr.23312
    • WANG Y, ZHANG D, ZHENG W, LUO J, BAI Y et al.: Multiple gene methylation of nonsmall cell lung cancers evaluated with 3-dimensional microarray. Cancer 2008; 112: 1325-1336. doi:10.1002/cncr.23312
    • (2008) Cancer , vol.112 , pp. 1325-1336
    • Wang, Y.1    Zhang, D.2    Zheng, W.3    Luo, J.4    Bai, Y.5
  • 36
    • 38349135680 scopus 로고    scopus 로고
    • High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer
    • doi:10.1073/pnas.0710735105
    • RAUCH TA, ZHONG X, WU X, WANG M, KERNSTINE KH et al.: High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer. Proc Natl Acad Sci USA 2008; 105: 252-257. doi:10.1073/pnas.0710735105
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 252-257
    • Rauch, T.A.1    Zhong, X.2    Wu, X.3    Wang, M.4    Kernstine, K.H.5


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