Inverse correlation of secreted frizzled-related protein 4 and β-catenin expression in endometrial stromal sarcomas

Journal of Pathology

Volumn 204, Issue 1, 2004, Pages 19-27

  Hrzenjak, Andelko ^a   Tippl, Michaela ^a   Kremser, Marie Luise ^a   Strohmeier, Bettina ^a   Guelly, Christian ^b   Neumeister, Doris ^a   Lax, Sigurd ^a   Moinfar, Farid ^a   Tabrizi, Ali Dastranj ^c   Isadi Moud, Nagres ^d   Zatloukal, Kurt ^a   Denk, Helmut ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

^b Biomedizinische Forschungsgesellschaft mbH   (Austria)

^c UNIVERSITY OF TABRIZ   (Iran)

^d UNIVERSITY OF TEHRAN   (Iran)

Author keywords

catenin; Endometrial stromal sarcoma; QRT PCR; Secreted frizzled related proteins; Wnt pathway

Indexed keywords

BETA CATENIN; COMPLEMENTARY DNA; FRIZZLED PROTEIN; PARAFFIN; TUMOR SUPPRESSOR PROTEIN; WNT PROTEIN;

ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORRELATION ANALYSIS; DEREGULATION; DNA HYBRIDIZATION; DNA LIBRARY; DNA SEQUENCE; ENDOMETRIUM SARCOMA; FEMALE; GENE TRANSLOCATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MOLECULAR CLONING; MOLECULAR MECHANICS; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; RARE DISEASE; SIGNAL TRANSDUCTION; SUPPRESSION SUBTRACTIVE HYBRIDIZATION; TISSUE SECTION;

BETA CATENIN; CYTOSKELETAL PROTEINS; DNA, NEOPLASM; ENDOMETRIAL NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IN SITU HYBRIDIZATION; NEOPLASM PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SARCOMA; TRANS-ACTIVATORS;

EID: 4544249671     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1616     Document Type: Article

References (43)

1. Mansi JL, Ramachandra S, Wiltshaw E, Fisher C. Endometrial stromal sarcomas. Gynecol Oncol 1990; 36: 113-118.
2. Norris HJ, Taylor HB. Mesenchymal tumors of the uterus. I. A clinical and pathological study of 53 endometrial stroma tumors. Cancer 1966; 19: 755-766.
3. Chang KL, Crabtree GS, Lim-Tan SK, Kempson RL, Hendrickson MR. Primary uterine endometrial stromal neoplasms. A clinicopathologic study of 117 cases. Am J Surg Pathol 1990; 14: 415-438.
4. Nordal RN, Kjorstad KE, Stenwig AE, Trope CG. Leiomyosarcoma (LMS) and endometrial stromal sarcoma (ESS) of the uterus. A survey of patients treated in the Norwegian Radium Hospital, 1976-1985. Int J Gynecol Cancer 1993; 3: 110-115.
5. Evans HL. Endometrial stromal sarcoma and poorly differentiated endometrial sarcoma. Cancer 1982; 50: 2170-2182.
6. Berchuck A, Rubin SC, Hoskins WJ, Saigo PE, Pierce VK, Lewis J. Treatment of endometrial stromal tumours. Gynecol Oncol 1990; 36: 60-65.
7. Yilmaz A, Rush DS, Soslow RA. Endometrial stromal sarcomas with unusual histologic features: a report of 24 primary and metastatic tumours emphasizing fibroblastic and smooth muscle differentiation. Am J Surg Pathol 2002; 26: 1142-1150.
8. Farhood AI, Abrams J. Immunohistochemistry of endometrial stromal sarcoma. Hum Pathol 1991; 22: 224-230.
9. Böcker W, Stegner HE. A light and electron microscopic study of endometrial sarcomas of the uterus. Virchows Arch 1985; 368: 141-156.
10. Fekete PS, Vellios R. The clinical and histologic spectrum of endometrial stromal neoplasm: a report of 41 cases. Int J Gynecol Pathol 1984; 3: 198-212.
11. Gil-Benso R, Lopez-Gines C, Navarro S, Carda C, Llombart-Bosch A. Endometrial stromal sarcomas: immunohistochemical, electron microscopical and cytogenetic findings in two cases. Virchows Arch 1999; 434: 307-314
12. Micci F, Walter CU, Teixeira MR, et al. Cytogenetic and molecular genetic analyses of endometrial stromal sarcoma: nonrandom involvement of chromosome arms 6p and 7p and confirmation of JAZF1/JJAZ1 gene fusion in t(7;17). Cancer Genet Cytogenet 2003; 144: 119-124.
13. Koontz JI, Soreng AL, Nucci M, et al. Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors. PNAS 2001; 98: 6348-6353.
14. Oliva E, Clement PB, Young RH. Endometrial stromal tumors: an update on a group of tumors with a protean phenotype. Adv Anat Pathol 2000; 7: 257-281.
15. Schena M, Shalon D, Davis RW, Brown PO. Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 1995; 270: 467-470.
16. Schena M, Shalon D, Heller R, Chai A, Brown PO, Davis RW. Parallel human genome analysis: microarray-based expression monitoring of 1000 genes. Proc Natl Acad Sci U S A 1996; 93: 10614-10619.
17. Rupp GM, Locker J. Purification and analysis of RNA from paraffin-embedded tissues. Biotechniques 1988; 6: 56-60.
18. Specht K, Richter T, Müller U, Walch A, Werner M, Höfler H. Quantitative gene expression analysis in microdissected archival formalin-fixed and paraffin-embedded tumour tissue. Am J Pathol 2001; 158: 419-429.
19. Fickert P, Trauner M, Fuchsbichler A, Stumpther C, Zatloukal K, Denk H. Cytokeratins as targets for bile acid-induced toxicity. Am J Pathol 2002; 160: 491-499.
20. Hartigan JA. Clustering. Annu Rev Biophys Bioeng 1973; 2: 81-101.
21. Weinstein JN, Myers TG, O'Connor PM, et al. An information-intensive approach to the molecular pharmacology of cancer. Science 1997; 275: 343-349.
22. Chu PG, Arber DA, Weiss LM, Chang KL. Utility of CD10 in distinguishing between endometrial stromal sarcoma and uterine smooth muscle tumours: an immunohistochemical comparison of 34 cases. Mod Pathol 2001; 14: 465-471.
23. McCluggage WG, Sumathi VP, Maxwell P. CD10 is a sensitive and diagnostically useful immunohistochemical marker of normal endometrial stroma and of endometrial stromal neoplasms. Histopathology 2001; 39: 273-278.
24. Edmonds BT, Wyckoff J, Yeung YG, et al. Elongation factor-1 alpha is an overexpressed actin binding protein in metastatic rat mammary adenocarcinoma. J Cell Sci 1996; 109: 2705-2714.
25. Tunuguntla R, Ripley D, Sang OX, Chegini N. Expression of matrix metalloproteinase-26 and tissue inhibitors of metalloproteinases TIPM-3 and -4 in benign endometrium and endometrial cancer. Gynecol Oncol 2003; 89: 453-459.
26. Wong SCC, Lo SFE, Lee KC, Yam JWP, Chan JKC, Hsiao WLW. Expression of frizzled-related protein and Wnt-signalling molecules in invasive human breast tumours. J Pathol 2002; 196: 145-153.
27. Moon RT, Brown JD, Yang-Snyder JA, Miller JR. Structurally related receptors and antagonists compete for secreted Wnt ligands. Cell 1997; 88: 725-728.
28. Zorn AM. Cell-cell signalling: Frog frizbees. Curr Biol 1997; 7: 501-504.
29. Dennis S, Aikawa W, Szeto W, d'Amore PA, Papkoff J. A secreted frizzled related protein, FrzA, selectively associates with Wnt-1 protein and regulates Wnt-1 signalling. J Cell Sci 1999; 112: 3815-3820.
30. Bafico A, Gazit A, Pramila T, Finch PW, Yaniv A, Aaronson SA. Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signalling. J Biol Chem 1999; 274: 16180-16187.
31. Huguet E, McMahon JA, McMahon AP, Bicknell R, Harris AL. Differential expression of human Wnt genes 2, 3, 4 and 7B in human breast cell lines and normal and disease states of human breast tissue. Cancer Res 1994; 54: 2615-2621.
32. Dale TC, Weber-Hall SJ, Smith K, et al. Compartment switching of Wnt-2 expression in human breast tumours. Cancer Res 1996; 56: 4320-4323.
33. Bui TD, Lako M, Lejeune S, et al. Isolation of a full-length human WNT7A gene implicated in limb development and cell transformation, and mapping to chromosome 3p25. Gene 1997; 189: 25-29.
34. Finch PW, He X, Kelley MJ, et al. Purification and molecular cloning of a secreted, frizzled-related antagonist of Wnt action. Proc Natl Acad Sci U S A 1997; 94: 6770-6775.
35. Leyns L, Bouwmeester T, Kim SH, Piccolo S, De Robertis M. Frzb-1 is a secreted antagonist of Wnt signalling expressed in the Spemann organizer. Cell 1997; 88: 747-756.
36. Wang S, Krinks M, Lin K, Luyten FP, Moos M Jr. Frzb, a secreted protein expressed in the Spemann organizer, binds and inhibits Wnt-8. Cell 1997; 88: 757-766.
37. Fukuhara K, Kariya M, Kita M, et al. Secreted frizzled related protein 1 is overexpressed in uterine leiomyomas, associated with a high estrogenic environment and unrelated to proliferative activity. J Clin Endocrin 2002; 87: 1729-1736.
38. Zhou Z, Wang J, Han X, Zhou J, Linder S. Up-regulation of human secreted frizzled homologue in apoptosis and its down-regulation in breast tumours. Int J Cancer 1998; 78: 95-99.
39. Navarro D, Cabrera JJ, Leon L, et al. Endometrial stromal sarcoma expression of estrogen receptors, progesterone receptors and estrogen-induced srp27 (24K) suggests hormone responsiveness. J Steroid Biochem Mol Biol 1992; 41: 589-596.
40. Sabini G, Chumas JC, Mann WJ. Steroid hormone receptors in endometrial stromal sarcomas. A biochemical and immunohistochemical study. Am J Clin Pathol 1992; 97: 381-386.
41. Abu-Jawdeh G, Comella N, Tomita Y, et al. Differential expression of frpHE: a novel human stromal protein of the secreted frizzled gene family, during the endometrial cycle and malignancy. Lab Invest 1999; 79: 439-447.
42. Morin PJ, Sparks AB, Korinek V, et al. Activation of beta-catenin-Tcf signalling in colon cancer by mutations in beta-catenin or APC. Science 1997; 275: 1787-1790.
43. Novak A, Dedhar S. Signalling through beta-catenin and Lef/Tcf. Cell Mol Life 1999; 56: 523-537.