메뉴 건너뛰기




Volumn 72, Issue 5, 2010, Pages 1208-1253

A mathematical model of HIV infection: Simulating T4, T8, macrophages, antibody, and virus via specific anti-HIV response in the presence of adaptation and tropism

Author keywords

HIV T cell subset dynamics; Infected macrophage dynamics with tropism and mutation

Indexed keywords

VIRUS ANTIBODY;

EID: 77954622136     PISSN: 00928240     EISSN: 15229602     Source Type: Journal    
DOI: 10.1007/s11538-009-9488-5     Document Type: Article
Times cited : (18)

References (70)
  • 1
    • 0036883678 scopus 로고    scopus 로고
    • Long-term survival and virus production in human primary macrophages infected by human immunodeficiency virus
    • Aquaro, S., Bagnarelli, P., Guenci, T., De Luca, A., Clement, M., Balestra, E., Caliò, R., Perno, C. F., 2002a. Long-term survival and virus production in human primary macrophages infected by human immunodeficiency virus. J. Med. Virol. 68(4), 479-488.
    • (2002) J. Med. Virol. , vol.68 , Issue.4 , pp. 479-488
    • Aquaro, S.1    Bagnarelli, P.2    Guenci, T.3    de Luca, A.4    Clement, M.5    Balestra, E.6    Caliò, R.7    Perno, C.F.8
  • 2
    • 0036289210 scopus 로고    scopus 로고
    • Macrophages and HIV infection: Therapeutical approaches toward this strategic virus reservoir
    • Aquaro, S., Caliò, R., Balzarini, J., Bellocchi, M. C., Garaci, E., Perno, C. F., 2002b. Macrophages and HIV infection: Therapeutical approaches toward this strategic virus reservoir. Antivir. Res. 55(2), 209-225.
    • (2002) Antivir. Res. , vol.55 , Issue.2 , pp. 209-225
    • Aquaro, S.1    Caliò, R.2    Balzarini, J.3    Bellocchi, M.C.4    Garaci, E.5    Perno, C.F.6
  • 4
    • 0024521053 scopus 로고
    • Incubation period of AIDS in San Francisco
    • Bacchetti, P., Moss, A. R., 1989. Incubation period of AIDS in San Francisco. Nature 338(6212), 251-253.
    • (1989) Nature , vol.338 , Issue.6212 , pp. 251-253
    • Bacchetti, P.1    Moss, A.R.2
  • 5
    • 0036571311 scopus 로고    scopus 로고
    • Dynamics of naive and memory CD4+ T lymphocytes in HIV-1 disease progression
    • Bajaria, S., Webb, G., Cloyd, M., Kirschner, D., 2002. Dynamics of naive and memory CD4+ T lymphocytes in HIV-1 disease progression. J. Acquir. Immune Defic. Syndr. 30, 41-58.
    • (2002) J. Acquir. Immune Defic. Syndr. , vol.30 , pp. 41-58
    • Bajaria, S.1    Webb, G.2    Cloyd, M.3    Kirschner, D.4
  • 7
    • 0032555117 scopus 로고    scopus 로고
    • Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection
    • Chun, T. W., Engel, D., Berrey, M. M., Shea, T., Corey, L., Fauci, A. S., 1998. Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection. Proc. Natl. Acad. Sci. USA 95(15), 8869-8873.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , Issue.15 , pp. 8869-8873
    • Chun, T.W.1    Engel, D.2    Berrey, M.M.3    Shea, T.4    Corey, L.5    Fauci, A.S.6
  • 9
    • 0032556872 scopus 로고    scopus 로고
    • HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes
    • Collins, K. L., Chen, B. K., Kalams, S. A., Walker, B. D., Baltimore, D., 1998. HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes. Nature 391, 397-401.
    • (1998) Nature , vol.391 , pp. 397-401
    • Collins, K.L.1    Chen, B.K.2    Kalams, S.A.3    Walker, B.D.4    Baltimore, D.5
  • 10
    • 0031575431 scopus 로고    scopus 로고
    • Change in coreceptor use correlates with disease progression in HIV-1 infected individuals
    • Connor, R. I., Sheridan, K. E., Ceradini, D., Choe, S., Landau, N. R., 1997. Change in coreceptor use correlates with disease progression in HIV-1 infected individuals. J. Exp. Med. 185(4), 621-628.
    • (1997) J. Exp. Med. , vol.185 , Issue.4 , pp. 621-628
    • Connor, R.I.1    Sheridan, K.E.2    Ceradini, D.3    Choe, S.4    Landau, N.R.5
  • 11
    • 0024330712 scopus 로고
    • Comparative assessment of antiretrovirals in human monocyte-macrophages and lymphoid cell lines acutely and chronically infected with the human immunodeficiency virus
    • Crowe, S. M., McGrath, M. S., Elbeik, T., Kirihara, J., Mills, J., 1989. Comparative assessment of antiretrovirals in human monocyte-macrophages and lymphoid cell lines acutely and chronically infected with the human immunodeficiency virus. J. Med. Virol. 29(3), 176-180.
    • (1989) J. Med. Virol. , vol.29 , Issue.3 , pp. 176-180
    • Crowe, S.M.1    McGrath, M.S.2    Elbeik, T.3    Kirihara, J.4    Mills, J.5
  • 12
    • 0025735965 scopus 로고
    • Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection
    • Daar, E. S., Moudgi, L. T., Meyer, R. D., Ho, D. D., 1991. Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection. N. Engl. J. Med. 324(14), 961-964.
    • (1991) N. Engl. J. Med. , vol.324 , Issue.14 , pp. 961-964
    • Daar, E.S.1    Moudgi, L.T.2    Meyer, R.D.3    Ho, D.D.4
  • 15
    • 0038639554 scopus 로고    scopus 로고
    • HIV and AIDS: 20 years of science
    • Fauci, A., 2003. HIV and AIDS: 20 years of science. Nat. Med. 9(7), 839-843.
    • (2003) Nat. Med. , vol.9 , Issue.7 , pp. 839-843
    • Fauci, A.1
  • 16
    • 34249736950 scopus 로고    scopus 로고
    • HIV-1-specific CTLs effectively suppress replication of HIV-1 in HIV-1-infected macrophages
    • Fujiwara, M., Takiguchi, M., 2007. HIV-1-specific CTLs effectively suppress replication of HIV-1 in HIV-1-infected macrophages. Blood 109(11), 4832-4838.
    • (2007) Blood , vol.109 , Issue.11 , pp. 4832-4838
    • Fujiwara, M.1    Takiguchi, M.2
  • 18
    • 0030684068 scopus 로고    scopus 로고
    • Colocalization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation
    • Greenberg, M. E., Bronson, S., Lock, M., Neumann, M., Pavlakis, G. N., Skowronski, J., 1997. Colocalization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation. EMBO J. 16, 6964-6976.
    • (1997) EMBO J. , vol.16 , pp. 6964-6976
    • Greenberg, M.E.1    Bronson, S.2    Lock, M.3    Neumann, M.4    Pavlakis, G.N.5    Skowronski, J.6
  • 19
    • 0036103096 scopus 로고    scopus 로고
    • CD4+ T-cell depletion in HIV infection: Are we closer to understanding the cause?
    • Commentary
    • Grossman, Z., Meier-Schellersheim, Sousa, A., Rui, M., Paul, V. W., 2002. CD4+ T-cell depletion in HIV infection: Are we closer to understanding the cause?. Nat. Med. 8(4), 319-323. Commentary.
    • (2002) Nat. Med. , vol.8 , Issue.4 , pp. 319-323
    • Grossman, Z.1    Meier-Schellersheim2    Sousa, A.3    Rui, M.4    Paul, V.W.5
  • 20
    • 77954000251 scopus 로고    scopus 로고
    • Clinical Overview of HIV Disease
    • University of California San Francisco
    • Hare, C. B., 2006. Clinical Overview of HIV Disease. HIV InSite Knowledge Base Chapter. University of California San Francisco. http://hivinsite. ucsf. edu/InSitepage=kb-03-01-01.
    • (2006) HIV InSite Knowledge Base Chapter
    • Hare, C.B.1
  • 21
    • 41149158001 scopus 로고    scopus 로고
    • Memory CD4 T cells emerge from effector T-cell progenitors
    • Harrington, L., Janowski, K., Oliver, J., Zajac, A., Weaver, C., 2008. Memory CD4 T cells emerge from effector T-cell progenitors. Nature 452, 356-360.
    • (2008) Nature , vol.452 , pp. 356-360
    • Harrington, L.1    Janowski, K.2    Oliver, J.3    Zajac, A.4    Weaver, C.5
  • 23
    • 0034685170 scopus 로고    scopus 로고
    • Effect of recent thymic emigrants on progression of HIV-1 disease
    • Hatzakis, A., Touloumi, G. et al., 2000. Effect of recent thymic emigrants on progression of HIV-1 disease. Lancet 355, 9204.
    • (2000) Lancet , vol.355 , pp. 9204
    • Hatzakis, A.1    Touloumi, G.2
  • 25
    • 0029940354 scopus 로고    scopus 로고
    • Viral counts in HIV infection
    • Ho, D. D., 1996. Viral counts in HIV infection. Science 272, 1124-1125.
    • (1996) Science , vol.272 , pp. 1124-1125
    • Ho, D.D.1
  • 26
    • 0031155367 scopus 로고    scopus 로고
    • Dynamics of HIV-1 replication in vivo
    • Ho, D. D., 1997. Dynamics of HIV-1 replication in vivo. Clin. Invest. 90(11), 2565-2567.
    • (1997) Clin. Invest. , vol.90 , Issue.11 , pp. 2565-2567
    • Ho, D.D.1
  • 27
    • 0028874048 scopus 로고
    • Rapid turnover of plasma virons and CD4 lymphocytes in HIV-1 infection
    • Ho, D. D., Neumann, U., Perelson, A., Chen, W., Leonard, J., Markowits, M., 1995. Rapid turnover of plasma virons and CD4 lymphocytes in HIV-1 infection. Nature 373, 123-126.
    • (1995) Nature , vol.373 , pp. 123-126
    • Ho, D.D.1    Neumann, U.2    Perelson, A.3    Chen, W.4    Leonard, J.5    Markowits, M.6
  • 28
    • 0035895214 scopus 로고    scopus 로고
    • Macrophages are the principal reservoir and sustain high virus loads in Rhesus macaques following the depletion of CD4+ T cells by a highly pathogenic SHIV: Implications for HIV-1 infections of man
    • Igarshi, T., et al., 2001. Macrophages are the principal reservoir and sustain high virus loads in Rhesus macaques following the depletion of CD4+ T cells by a highly pathogenic SHIV: Implications for HIV-1 infections of man. Proc. Natl. Acad. Sci. 98, 658-663.
    • (2001) Proc. Natl. Acad. Sci. , vol.98 , pp. 658-663
    • Igarshi, T.1
  • 29
    • 0003616579 scopus 로고    scopus 로고
    • 3rd edn., Amsterdam: Elsevier Science Ltd/Garland Publishing
    • Janeway, C., Travers, P., Walport, M., 1996. Immuno Biology, 3rd edn. Elsevier Science Ltd/Garland Publishing, Amsterdam.
    • (1996) Immuno Biology
    • Janeway, C.1    Travers, P.2    Walport, M.3
  • 31
    • 24944439857 scopus 로고    scopus 로고
    • Opportunistic infection as a cause of transient viremia in chronically infected HIV patients under treatment with HAART
    • Jones, L. E., Perelson, A. S., 2005. Opportunistic infection as a cause of transient viremia in chronically infected HIV patients under treatment with HAART. Bull. Math. Biol. 67, 1227-1251.
    • (2005) Bull. Math. Biol. , vol.67 , pp. 1227-1251
    • Jones, L.E.1    Perelson, A.S.2
  • 33
    • 33750451933 scopus 로고    scopus 로고
    • Viral and latent reservoir persistence in HIV-1 infected patients on therapy
    • Kim, H., Perelson, A., 2006. Viral and latent reservoir persistence in HIV-1 infected patients on therapy. PLoS Comput. Biol. 2(10, e135), 1235-1247.
    • (2006) PLoS Comput. Biol. , vol.2 , Issue.10 , pp. 1235-1247
    • Kim, H.1    Perelson, A.2
  • 34
    • 0000653357 scopus 로고
    • A model for the immune system response to HIV: AZT treatment studies
    • Theory of Epidemics, Winnipeg: Wuerz Publishing Ltd
    • Kirschner, D. E., Perelson, A., 1995. A model for the immune system response to HIV: AZT treatment studies. In: Mathematical Population Dynamics: Analysis of Heterogeneity, Theory of Epidemics, vol. 1, pp. 295-310. Wuerz Publishing Ltd., Winnipeg.
    • (1995) Mathematical Population Dynamics: Analysis of Heterogeneity , vol.1 , pp. 295-310
    • Kirschner, D.E.1    Perelson, A.2
  • 35
    • 0030095028 scopus 로고    scopus 로고
    • A model for treatment strategy in the chemotherapy of AIDS
    • Kirschner, D. E., Webb, G. F., 1996. A model for treatment strategy in the chemotherapy of AIDS. Bull. Math. Biol. 58, 367-391.
    • (1996) Bull. Math. Biol. , vol.58 , pp. 367-391
    • Kirschner, D.E.1    Webb, G.F.2
  • 36
    • 0030845596 scopus 로고    scopus 로고
    • Mechanism of human immunodefifiency virus type localization in CD4-negative thymocytes: Differentiation from a CD4-positive precursor allow productive infection
    • Kitchen, G., Uittenbogaart, C. H., Zack, J., 1997. Mechanism of human immunodefifiency virus type localization in CD4-negative thymocytes: Differentiation from a CD4-positive precursor allow productive infection. J. Virol. 8, 5713-5722.
    • (1997) J. Virol. , vol.8 , pp. 5713-5722
    • Kitchen, G.1    Uittenbogaart, C.H.2    Zack, J.3
  • 37
    • 0032880105 scopus 로고    scopus 로고
    • Adaptation of a CCR5-using, primary human immunodeficiency virus type 1 isolate for CD4 independent replication
    • Kolchinsky, P., Mirzabekov, T., Furan, M., Kiprilov, E., Cayabyab, M., Mooney, L. J., Choe, H., Sodroski, J., 1999. Adaptation of a CCR5-using, primary human immunodeficiency virus type 1 isolate for CD4 independent replication. J. Virol. 73(10), 8120-8126.
    • (1999) J. Virol. , vol.73 , Issue.10 , pp. 8120-8126
    • Kolchinsky, P.1    Mirzabekov, T.2    Furan, M.3    Kiprilov, E.4    Cayabyab, M.5    Mooney, L.J.6    Choe, H.7    Sodroski, J.8
  • 38
    • 0028337166 scopus 로고
    • Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
    • Koup, R. A., Safrit, J. T., Cao, Y., Andrews, C. A., McLeod, G., Borkowsky, W., Farthing, C., Ho, D. D., 1994. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J. Virol. 68(7), 4650-4655.
    • (1994) J. Virol. , vol.68 , Issue.7 , pp. 4650-4655
    • Koup, R.A.1    Safrit, J.T.2    Cao, Y.3    Andrews, C.A.4    McLeod, G.5    Borkowsky, W.6    Farthing, C.7    Ho, D.D.8
  • 39
    • 0003536924 scopus 로고    scopus 로고
    • 3rd edn., New York: W.H. Freeman and Co
    • Kuby, J., 1997. Immunology, 3rd edn. W. H. Freeman and Co., New York.
    • (1997) Immunology
    • Kuby, J.1
  • 40
    • 0030749208 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 infection of mature CD3hiCD8+ thymocytes
    • Lee, S., Goldstein, H., Baseler, M., Adelsberger, J., Golding, H., 1997. Human immunodeficiency virus type 1 infection of mature CD3hiCD8+ thymocytes. J. Virol. 71(9), 6671-6676.
    • (1997) J. Virol. , vol.71 , Issue.9 , pp. 6671-6676
    • Lee, S.1    Goldstein, H.2    Baseler, M.3    Adelsberger, J.4    Golding, H.5
  • 41
    • 33846498445 scopus 로고    scopus 로고
    • Coreceptor switching in HIV-1 subtype B and subtype C
    • Mugwagwa, T., Witten, G., 2006. Coreceptor switching in HIV-1 subtype B and subtype C. Bull. Math. Biol. 68, 55-77.
    • (2006) Bull. Math. Biol. , vol.68 , pp. 55-77
    • Mugwagwa, T.1    Witten, G.2
  • 42
    • 0036170921 scopus 로고    scopus 로고
    • Determination of a statistically valid neutralization titer in plasma that confers protection against simian-human immunodeficiency virus challenge following passive transfer of high-titered neutralizing antibodies
    • Nishimura, Y., Igarashi, T., Haigwood, N., Sadjadpour, R., Plishka, R. J., Buckler-White, A., et al., 2002. Determination of a statistically valid neutralization titer in plasma that confers protection against simian-human immunodeficiency virus challenge following passive transfer of high-titered neutralizing antibodies. J. Virol. 76, 2123-2130.
    • (2002) J. Virol. , vol.76 , pp. 2123-2130
    • Nishimura, Y.1    Igarashi, T.2    Haigwood, N.3    Sadjadpour, R.4    Plishka, R.J.5    Buckler-White, A.6
  • 43
    • 85012474693 scopus 로고
    • New concepts in the immunopathogenesis of human immunodeficiency virus infection
    • Pantaleo, G., Graziosi, C., Fauci, A. S., 1993. New concepts in the immunopathogenesis of human immunodeficiency virus infection. N. Engl. J. Med. 328, 327-335.
    • (1993) N. Engl. J. Med. , vol.328 , pp. 327-335
    • Pantaleo, G.1    Graziosi, C.2    Fauci, A.S.3
  • 44
    • 0001918317 scopus 로고    scopus 로고
    • Mathematical analysis of HIV-1 dynamics in vivo
    • Perelson, A. S., Nelson, P., 1999. Mathematical analysis of HIV-1 dynamics in vivo. SIAM Rev. 41, 3-44.
    • (1999) SIAM Rev. , vol.41 , pp. 3-44
    • Perelson, A.S.1    Nelson, P.2
  • 45
    • 0027457101 scopus 로고
    • The dynamics of HIV infection of CD4+ T cells
    • Perelson, A. S., Kirschner, D. E., DeBoer, R., 1993. The dynamics of HIV infection of CD4+ T cells. Math. Biosci. 114, 81-125.
    • (1993) Math. Biosci. , vol.114 , pp. 81-125
    • Perelson, A.S.1    Kirschner, D.E.2    Deboer, R.3
  • 46
    • 0029967721 scopus 로고    scopus 로고
    • HIV-1 dynamics in vivo: Viron clearance rate, infected cell life-span, and viral generation time
    • Perelson, A. S., Neumann, A. U., Markowitz, M., Leonard, J. M., Ho, D. D., 1996. HIV-1 dynamics in vivo: viron clearance rate, infected cell life-span, and viral generation time. Science 271(5255), 1582-1586.
    • (1996) Science , vol.271 , Issue.5255 , pp. 1582-1586
    • Perelson, A.S.1    Neumann, A.U.2    Markowitz, M.3    Leonard, J.M.4    Ho, D.D.5
  • 47
    • 0027410369 scopus 로고
    • High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR
    • Piatak, M., Saag, M. S., Yang, L. C., Clark, S. J., Kappes, J. C., Luk, K. C., Hahn, B. H., Shaw, G. M., Lifson, J. D., 1993. High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR. Science 259(5102), 1749-1754.
    • (1993) Science , vol.259 , Issue.5102 , pp. 1749-1754
    • Piatak, M.1    Saag, M.S.2    Yang, L.C.3    Clark, S.J.4    Kappes, J.C.5    Luk, K.C.6    Hahn, B.H.7    Shaw, G.M.8    Lifson, J.D.9
  • 48
    • 12144286858 scopus 로고    scopus 로고
    • Frequent detection of acute primary HIV infection in men in Malawi
    • Pilcher, C. D., Price, M. A., Hoffman, I., 2004. Frequent detection of acute primary HIV infection in men in Malawi. AIDS 18, 517-524.
    • (2004) Aids , vol.18 , pp. 517-524
    • Pilcher, C.D.1    Price, M.A.2    Hoffman, I.3
  • 49
    • 33745440781 scopus 로고    scopus 로고
    • HIV tropism: Diagnostic tools and implications for disease progression and treatment with entry inhibitors
    • Poveda, E., Briz, V., Quiñones-Mateu, M., Soriano, V., 2006. HIV tropism: Diagnostic tools and implications for disease progression and treatment with entry inhibitors. AIDS 20(10), 1359-1367.
    • (2006) Aids , vol.20 , Issue.10 , pp. 1359-1367
    • Poveda, E.1    Briz, V.2    Quiñones-Mateu, M.3    Soriano, V.4
  • 50
    • 0037389643 scopus 로고    scopus 로고
    • Rapid evolution of the neutralizing antibody response to HIV type I infection
    • Richman, D. D., Wrin, T., Little, S. J., Petropoulos, C. J., 2003. Rapid evolution of the neutralizing antibody response to HIV type I infection. Proc. Natl. Acad. Sci. USA 100, 4144-4149.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 4144-4149
    • Richman, D.D.1    Wrin, T.2    Little, S.J.3    Petropoulos, C.J.4
  • 54
    • 0032550369 scopus 로고    scopus 로고
    • Turnover of CD4+ and CD8+ T lymphocytes in HIV-1 infection in healthy individuals as measured by Ki-67 antigen
    • Sachsenberg, N., Perelson, A. S., Yerly, S., 1998. Turnover of CD4+ and CD8+ T lymphocytes in HIV-1 infection in healthy individuals as measured by Ki-67 antigen. J. Exp. Med. 187, 1295-1303.
    • (1998) J. Exp. Med. , vol.187 , pp. 1295-1303
    • Sachsenberg, N.1    Perelson, A.S.2    Yerly, S.3
  • 57
    • 77954624897 scopus 로고    scopus 로고
    • AIDS vaccine tests well in monkeys
    • Seppa, N., 2000. AIDS vaccine tests well in monkeys. Sci. News 158, 260.
    • (2000) Sci. News , vol.158 , pp. 260
    • Seppa, N.1
  • 59
    • 24944518559 scopus 로고    scopus 로고
    • Enhanced culture assay for detection and quantization of latently infected, resting CD4+ T-cells carrying replication-competent virus in HIV-1-infected individuals
    • Siliciano, J. D., Siliciano, R. F., 2005. Enhanced culture assay for detection and quantization of latently infected, resting CD4+ T-cells carrying replication-competent virus in HIV-1-infected individuals. Methods Mol. Biol. 304, 3-15.
    • (2005) Methods Mol. Biol. , vol.304 , pp. 3-15
    • Siliciano, J.D.1    Siliciano, R.F.2
  • 60
    • 0034615789 scopus 로고    scopus 로고
    • Modeling plasma virus concentration and CD4+ T cell kinetics during primary HIV infection
    • Stafford, M., Cao, Y., Ho, D., Corey, L., Mackall, C., Gress, R., Perelson, A., 2000. Modeling plasma virus concentration and CD4+ T cell kinetics during primary HIV infection. J. Theor. Biol. 203(3), 285-301.
    • (2000) J. Theor. Biol. , vol.203 , Issue.3 , pp. 285-301
    • Stafford, M.1    Cao, Y.2    Ho, D.3    Corey, L.4    Mackall, C.5    Gress, R.6    Perelson, A.7
  • 61
    • 0037131212 scopus 로고    scopus 로고
    • Antiviral activity of the neutralizing antibodies 2F5 and 2G12 in asymptomatic HIV-1-infected humans: A phase I evaluation
    • Stiegler, G., Armbruster, C., Vcelar, B., Stoiber, H., Kunert, R., Michael, N. L., et al., 2001. Antiviral activity of the neutralizing antibodies 2F5 and 2G12 in asymptomatic HIV-1-infected humans: A phase I evaluation. AIDS 16, 2019-2025.
    • (2001) Aids , vol.16 , pp. 2019-2025
    • Stiegler, G.1    Armbruster, C.2    Vcelar, B.3    Stoiber, H.4    Kunert, R.5    Michael, N.L.6
  • 62
    • 0035836367 scopus 로고    scopus 로고
    • HIV-1 Nef blocks transport of MHC class I molecules to the cell surface via a PI 3-kinase-dependent pathway
    • Swann, S. A., Williams, M., Story, C. M., Bobbitt, K. R., Fleis, R., Collins, K. L., 2001. HIV-1 Nef blocks transport of MHC class I molecules to the cell surface via a PI 3-kinase-dependent pathway. Virology 282, 267-277.
    • (2001) Virology , vol.282 , pp. 267-277
    • Swann, S.A.1    Williams, M.2    Story, C.M.3    Bobbitt, K.R.4    Fleis, R.5    Collins, K.L.6
  • 63
    • 27644599799 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 can establish latent infection in resting CD4+ T cells in the absence of activating stimuli
    • Swiggard, W. J., Baytop, C., Yu, J. J., Dai, J., Li, C., Schretzenmair, R., Theodosopoulos, T., O'Doherty, U., 2005. Human immunodeficiency virus type 1 can establish latent infection in resting CD4+ T cells in the absence of activating stimuli. J. Virol. 79(22), 14179-14188.
    • (2005) J. Virol. , vol.79 , Issue.22 , pp. 14179-14188
    • Swiggard, W.J.1    Baytop, C.2    Yu, J.J.3    Dai, J.4    Li, C.5    Schretzenmair, R.6    Theodosopoulos, T.7    O'Doherty, U.8
  • 64
    • 0003771494 scopus 로고
    • 3rd edn., Fort Worth Texas: Saunders College Publishing (Harcourt Brace Jovanovich)
    • Tizard, I., 1992. Immunology, An Introduction. 3rd edn. Saunders College Publishing (Harcourt Brace Jovanovich), Fort Worth Texas.
    • (1992) Immunology, An Introduction
    • Tizard, I.1
  • 65
    • 77954625271 scopus 로고    scopus 로고
    • Tran, M. M., 1999. Mathematical model of HIV in vivo. Masters Thesis, New Jersey City University [unpublished].
  • 66
    • 34250811507 scopus 로고    scopus 로고
    • The role of human leukocyte antigen E and G in HIV Infection
    • Tripathi, P., Agrawal, S., 2007. The role of human leukocyte antigen E and G in HIV Infection. AIDS 21(11), 1395-1404.
    • (2007) Aids , vol.21 , Issue.11 , pp. 1395-1404
    • Tripathi, P.1    Agrawal, S.2
  • 67
    • 0030589546 scopus 로고    scopus 로고
    • Preliminary in vitro growth cycle and transmission studies of HIV-1 in an autologous primary cell assay of blood-derived macrophages and peripheral blood mononuclear cells
    • Tsai, W. P., Conley, S. R., Kung, H. F., Garrity, R. R., Nara, P. L., 1996. Preliminary in vitro growth cycle and transmission studies of HIV-1 in an autologous primary cell assay of blood-derived macrophages and peripheral blood mononuclear cells. Virology 226(2), 205-216.
    • (1996) Virology , vol.226 , Issue.2 , pp. 205-216
    • Tsai, W.P.1    Conley, S.R.2    Kung, H.F.3    Garrity, R.R.4    Nara, P.L.5
  • 68
    • 0034662934 scopus 로고    scopus 로고
    • CTL recognition of cells latently infected with Kaposi's sarcoma-associated herpes virus
    • Walker, B. D., Scadden, D. T., 2000. CTL recognition of cells latently infected with Kaposi's sarcoma-associated herpes virus. J. Immunol. 165(4), 2077-2083.
    • (2000) J. Immunol. , vol.165 , Issue.4 , pp. 2077-2083
    • Walker, B.D.1    Scadden, D.T.2
  • 69
    • 58149473498 scopus 로고    scopus 로고
    • Treatment of HIV- infected parients with Ge protein-derived macrophage activating factor (GeMAF) eradicates HIV-infection
    • Italy: Medimond, Bolona
    • Yamamoto, N., Ueda, M., Benson, C. E., 2007. Treatment of HIV- infected parients with Ge protein-derived macrophage activating factor (GeMAF) eradicates HIV-infection. In: Proc. 13 Int. Cong. Immunol. Italy: Medimond, Bolona, pp. 35-38.
    • (2007) Proc. 13 Int. Cong. Immunol , pp. 35-38
    • Yamamoto, N.1    Ueda, M.2    Benson, C.E.3
  • 70
    • 58149250984 scopus 로고    scopus 로고
    • Immunotherapy of HIV-infected patients with Gc protein-derived macrophage activating factor (GcMAF)
    • Yamamoto, N., Ushijima, N., Koga, Y., 2009. Immunotherapy of HIV-infected patients with Gc protein-derived macrophage activating factor (GeMAF). J. Med. Virol. 81, 16-26.
    • (2009) J. Med. Virol. , vol.81 , pp. 16-26
    • Yamamoto, N.1    Ushijima, N.2    Koga, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.