-
1
-
-
0037217406
-
Automated design of specificity in molecular recognition
-
Havranek, J. J.; Harbury, P. B. Automated design of specificity in molecular recognition. Nat. Struct. Biol. 2003, 10, 45-52.
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 45-52
-
-
Havranek, J.J.1
Harbury, P.B.2
-
2
-
-
1842577654
-
Computational redesign of proteinprotein interaction specificity
-
Kortemme, T.; Joachimiak, L. A.; Bullock, A. N.; Schuler, A. D.; Stoddard, B. L.; Baker, D. Computational redesign of proteinprotein interaction specificity. Nat. Struct. Mol. Biol. 2004, 11, 371-379.
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 371-379
-
-
Kortemme, T.1
Joachimiak, L.A.2
Bullock, A.N.3
Schuler, A.D.4
Stoddard, B.L.5
Baker, D.6
-
3
-
-
0034039797
-
Electrostatic aspects of protein-protein interactions
-
Sheinerman, F. B.; Norel, R.; Honig, B. Electrostatic aspects of protein-protein interactions. Curr. Opin. Struct. Biol. 2000, 10, 153-159.
-
(2000)
Curr. Opin. Struct. Biol.
, vol.10
, pp. 153-159
-
-
Sheinerman, F.B.1
Norel, R.2
Honig, B.3
-
4
-
-
0035160537
-
Barstar is electrostatically optimized for tight binding to barnase
-
Lee, L. P.; Tidor, B. Barstar is electrostatically optimized for tight binding to barnase. Nat. Struct. Biol. 2001, 8, 73-76.
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 73-76
-
-
Lee, L.P.1
Tidor, B.2
-
5
-
-
18644376965
-
Electrostatic recognition and induced fit in the kappa-PVIIA toxin binding to Shaker potassium channel
-
Huang, X.; Dong, F.; Zhou, H. X. Electrostatic recognition and induced fit in the kappa-PVIIA toxin binding to Shaker potassium channel. J. Am. Chem. Soc. 2005, 127, 6836-6849.
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 6836-6849
-
-
Huang, X.1
Dong, F.2
Zhou, H.X.3
-
6
-
-
27744498365
-
Electrostatics in computational protein design
-
Vizcarra, C. L.; Mayo, S. L. Electrostatics in computational protein design. Curr. Opin. Chem. Biol. 2005, 9, 622-626.
-
(2005)
Curr. Opin. Chem. Biol.
, vol.9
, pp. 622-626
-
-
Vizcarra, C.L.1
Mayo, S.L.2
-
7
-
-
33748476481
-
Electrostatic properties of proteinprotein complexes
-
Kundrotas, P. J.; Alexov, E. Electrostatic properties of proteinprotein complexes. Biophys. J. 2006, 91, 1724-1736.
-
(2006)
Biophys. J.
, vol.91
, pp. 1724-1736
-
-
Kundrotas, P.J.1
Alexov, E.2
-
8
-
-
49649113677
-
Structural basis of a potent peptide inhibitor designed for Kv1.3 channel, a therapeutic target of autoimmune disease
-
Han, S.; Yi, H.; Yin, S. J.; Chen, Z. Y.; Liu, H.; Cao, Z. J.; Wu, Y. L.; Li, W. X. Structural basis of a potent peptide inhibitor designed for Kv1.3 channel, a therapeutic target of autoimmune disease. J. Biol. Chem. 2008, 283, 19058-19065.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 19058-19065
-
-
Han, S.1
Yi, H.2
Yin, S.J.3
Chen, Z.Y.4
Liu, H.5
Cao, Z.J.6
Wu, Y.L.7
Li, W.X.8
-
9
-
-
0034073515
-
Electrostatic interaction between charybdotoxin and a tetrameric mutant of Shaker K+ channels
-
Thompson, J.; Begenisich, T. Electrostatic interaction between charybdotoxin and a tetrameric mutant of Shaker K+ channels. Biophys. J. 2000, 78, 2382-2391.
-
(2000)
Biophys. J.
, vol.78
, pp. 2382-2391
-
-
Thompson, J.1
Begenisich, T.2
-
10
-
-
3042814574
-
Simulation of the interaction between ScyTx and small conductance calciumactivated potassium channel by docking and MM-PBSA
-
Wu, Y.; Cao, Z.; Yi, H.; Jiang, D.; Mao, X.; Liu, H.; Li, W. Simulation of the interaction between ScyTx and small conductance calciumactivated potassium channel by docking and MM-PBSA. Biophys. J. 2004, 87, 105-112.
-
(2004)
Biophys. J.
, vol.87
, pp. 105-112
-
-
Wu, Y.1
Cao, Z.2
Yi, H.3
Jiang, D.4
Mao, X.5
Liu, H.6
Li, W.7
-
11
-
-
38549168519
-
Molecular basis of inhibitory peptide maurotoxin recognizing Kv1.2 channel explored by ZDOCK and molecular dynamic simulations
-
Yi, H.; Qiu, S.; Cao, Z.; Wu, Y.; Li, W. Molecular basis of inhibitory peptide maurotoxin recognizing Kv1.2 channel explored by ZDOCK and molecular dynamic simulations. Proteins 2008, 70, 844-854.
-
(2008)
Proteins
, vol.70
, pp. 844-854
-
-
Yi, H.1
Qiu, S.2
Cao, Z.3
Wu, Y.4
Li, W.5
-
12
-
-
0032478818
-
The structure of the potassium channel: Molecular basis of K+ conduction and selectivity
-
Doyle, D. A.; Morais Cabral, J.; Pfuetzner, R. A.; Kuo, A.; Gulbis, J. M.; Cohen, S. L.; Chait, B. T.; MacKinnon, R. The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science 1998, 280, 69-77.
-
(1998)
Science
, vol.280
, pp. 69-77
-
-
Doyle, D.A.1
Morais Cabral, J.2
Pfuetzner, R.A.3
Kuo, A.4
Gulbis, J.M.5
Cohen, S.L.6
Chait, B.T.7
MacKinnon, R.8
-
13
-
-
23244456428
-
Crystal structure of a mammalian voltage-dependent Shaker family K+ channel
-
Long, S. B.; Campbell, E. B.; Mackinnon, R. Crystal structure of a mammalian voltage-dependent Shaker family K+ channel. Science 2005, 309, 897-903.
-
(2005)
Science
, vol.309
, pp. 897-903
-
-
Long, S.B.1
Campbell, E.B.2
MacKinnon, R.3
-
14
-
-
17744406515
-
Current views on scorpion toxins specific for K+-channels
-
Rodriguez de la Vega, R. C.; Possani, L. D. Current views on scorpion toxins specific for K+-channels. Toxicon 2004, 43, 865-875.
-
(2004)
Toxicon
, vol.43
, pp. 865-875
-
-
Rodriguez De La Vega R.C1
Possani, L.D.2
-
15
-
-
12244281787
-
Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes
-
Martin, L.; Stricher, F.; Misse, D.; Sironi, F.; Pugniere, M.; Barthe, P.; Prado-Gotor, R.; Freulon, I.; Magne, X.; Roumestand, C.; Menez, A.; Lusso, P.; Veas, F.; Vita, C. Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes. Nat. Biotechnol. 2003, 21, 71-76.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 71-76
-
-
Martin, L.1
Stricher, F.2
Misse, D.3
Sironi, F.4
Pugniere, M.5
Barthe, P.6
Prado-Gotor, R.7
Freulon, I.8
Magne, X.9
Roumestand, C.10
Menez, A.11
Lusso, P.12
Veas, F.13
Vita, C.14
-
16
-
-
30044444119
-
Pharmacological profiling of Orthochirus scrobiculosus toxin 1 analogs with a trimmed N-terminal domain
-
Mouhat, S.; Teodorescu, G.; Homerick, D.; Visan, V.; Wulff, H.; Wu, Y.; Grissmer, S.; Darbon, H.; De Waard, M.; Sabatier, J. M. Pharmacological profiling of Orthochirus scrobiculosus toxin 1 analogs with a trimmed N-terminal domain. Mol. Pharmacol. 2006, 69, 354-362.
-
(2006)
Mol. Pharmacol.
, vol.69
, pp. 354-362
-
-
Mouhat, S.1
Teodorescu, G.2
Homerick, D.3
Visan, V.4
Wulff, H.5
Wu, Y.6
Grissmer, S.7
Darbon, H.8
De Waard, M.9
Sabatier, J.M.10
-
17
-
-
0038526303
-
ZDOCK: An initial-stage protein-docking algorithm
-
Chen, R.; Li, L.; Weng, Z. ZDOCK: an initial-stage protein-docking algorithm. Proteins 2003, 52, 80-87.
-
(2003)
Proteins
, vol.52
, pp. 80-87
-
-
Chen, R.1
Li, L.2
Weng, Z.3
-
18
-
-
0037079570
-
Computational alanine scanning of the 1:1 human growth hormone-receptor complex
-
Huo, S.; Massova, I.; Kollman, P. A. Computational alanine scanning of the 1:1 human growth hormone-receptor complex. J. Comput. Chem. 2002, 23, 15-27.
-
(2002)
J. Comput. Chem.
, vol.23
, pp. 15-27
-
-
Huo, S.1
Massova, I.2
Kollman, P.A.3
-
19
-
-
9244260409
-
-
University of California: San Francisco CA
-
Case, D. A. Cheatham, T. A. D. T. E., III Simmerling, C. L. Wang, J. Duke, R. E. Luo, R. Merz, K. M. Wang, B. Pearlman, D. A. Crowley, M. Brozell, S. Tsui, V. Gohlke, H. Mongan, J. Hornak, V. Cui, G. Beroza, P. Schafmeister, C. Caldwell, J. W. Ross, and W. S. Kollman., P. A. Amber 8 University of California: San Francisco, CA, 2004.
-
(2004)
Amber 8
-
-
Case, D.A.C.1
Simmerling III, T.A.D.T.E.2
Wang, C.L.3
Duke, J.4
Luo, R.E.5
Merz, R.6
Wang, K.M.7
Pearlman, B.8
Crowley, D.A.9
Brozell, M.10
Tsui, S.11
Gohlke, V.12
Mongan, H.13
Hornak, J.14
Cui, V.15
Beroza, G.16
Schafmeister, P.17
Caldwell, C.18
Ross, J.W.19
Kollman., W.S.20
more..
-
20
-
-
0037176852
-
Gene expression, mutation, and structure-function relationship of scorpion toxin BmP05 active on SKCa channels
-
Wu, J. J.; He, L. L.; Zhou, Z.; Chi, C. W. Gene expression, mutation, and structure-function relationship of scorpion toxin BmP05 active on SKCa channels. Biochemistry 2002, 41, 2844-2849.
-
(2002)
Biochemistry
, vol.41
, pp. 2844-2849
-
-
Wu, J.J.1
He, L.L.2
Zhou, Z.3
Chi, C.W.4
-
21
-
-
0035900701
-
Design and characterization of a highly selective peptide inhibitor of the small conductance calcium-activated K+ channel
-
Shakkottai, V. G.; Regaya, I.; Wulff, H.; Fajloun, Z.; Tomita, H.; Fathallah, M.; Cahalan, M. D.; Gargus, J. J.; Sabatier, J. M.; Chandy, K. G. Design and characterization of a highly selective peptide inhibitor of the small conductance calcium-activated K+ channel, SkCa2. J. Biol. Chem. 2001, 276, 43145-43151.
-
(2001)
SkCa2. J. Biol. Chem.
, vol.276
, pp. 43145-43151
-
-
Shakkottai, V.G.1
Regaya, I.2
Wulff, H.3
Fajloun, Z.4
Tomita, H.5
Fathallah, M.6
Cahalan, M.D.7
Gargus, J.J.8
Sabatier, J.M.9
Chandy, K.G.10
-
22
-
-
52949110988
-
Animal toxins acting on voltage-gated potassium channels
-
Mouhat, S.; Andreotti, N.; Jouirou, B.; Sabatier, J. M. Animal toxins acting on voltage-gated potassium channels. Curr. Pharm. Des. 2008, 14, 2503-2518.
-
(2008)
Curr. Pharm. Des.
, vol.14
, pp. 2503-2518
-
-
Mouhat, S.1
Andreotti, N.2
Jouirou, B.3
Sabatier, J.M.4
-
23
-
-
44849093511
-
K+ channel modulators for the treatment of neurological disorders and autoimmune diseases
-
Wulff, H.; Zhorov, B. S. K+ channel modulators for the treatment of neurological disorders and autoimmune diseases. Chem. Rev. 2008, 108, 1744-1773.
-
(2008)
Chem. Rev.
, vol.108
, pp. 1744-1773
-
-
Wulff, H.1
Zhorov, B.S.2
-
24
-
-
33751232672
-
Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases
-
Beeton, C.; Wulff, H.; Standifer, N. E.; Azam, P.; Mullen, K. M.; Pennington, M. W.; Kolski-Andreaco, A.; Wei, E.; Grino, A.; Counts, D. R.; Wang, P. H.; LeeHealey, C. J. B. S. A.; Sankaranarayanan, A.; Homerick, D.; Roeck, W. W.; Tehranzadeh, J.; Stanhope, K. L.; Zimin, P.; Havel, P. J.; Griffey, S.; Knaus, H. G.; Nepom, G. T.; Gutman, G. A.; Calabresi, P. A.; Chandy, K. G. Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases. Proc. Natl. Acad. Sci. USA 2006, 103, 17414-17419.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 17414-17419
-
-
Beeton, C.1
Wulff, H.2
Standifer, N.E.3
Azam, P.4
Mullen, K.M.5
Pennington, M.W.6
Kolski-Andreaco, A.7
Wei, E.8
Grino, A.9
Counts, D.R.10
Wang, P.H.11
Leehealey, C.J.B.S.A.12
Sankaranarayanan, A.13
Homerick, D.14
Roeck, W.W.15
Tehranzadeh, J.16
Stanhope, K.L.17
Zimin, P.18
Havel, P.J.19
Griffey, S.20
Knaus, H.G.21
Nepom, G.T.22
Gutman, G.A.23
Calabresi, P.A.24
Chandy, K.G.25
more..
|