Administration of capsule-selective endosialidase E minimizes upregulation of organ gene expression induced by experimental systemic infection with Escherichia coli K1

Microbiology

Volumn 156, Issue 7, 2010, Pages 2205-2215

  Zelmer, Andrea ^a   Martin, Melissa J ^b   Gundogdu, Ozan ^b   Birchenough, George ^a   Lever, Rebecca ^a   Wren, Brendan W ^b   Luzio, J Paul ^c   Taylor, Peter W ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CHEMOKINE; APOLIPOPROTEIN; BETA CHEMOKINE; CALGRANULIN A; CCAAT ENHANCER BINDING PROTEIN DELTA; CD14 ANTIGEN; COLLAGENASE 3; COLONY STIMULATING FACTOR; COMPLEMENT COMPONENT C3; ENDOSIALIDASE E; GELATINASE B; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOCALIN; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; PEPTIDOGLYCAN RECOGNITION PROTEIN; PHOSPHOLIPASE A2 GROUP II; PLECKSTRIN; PROSTAGLANDIN E SYNTHASE; PROSTAGLANDIN ENDOPEROXIDE; RECOMBINANT ENZYME; SCRAMBLASE; SELECTIN; SERINE PROTEINASE INHIBITOR; TRYPTOPHAN HYDROXYLASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; ENDO-N-ACETYLNEURAMINIDASE; POLYSIALIC ACID; SIALIC ACID DERIVATIVE; SIALIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTEREMIA; BACTERIAL COLONIZATION; BACTERIAL MEMBRANE; BACTERIAL VIRULENCE; BIOSYNTHESIS; BRAIN INJURY; BRAIN TISSUE; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTION; ESCHERICHIA COLI K1; GENE EXPRESSION; GENETIC TRANSCRIPTION; HOST; INFLAMMATION; INNATE IMMUNITY; LIVER; MENINX; MOLECULAR WEIGHT; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; SPLEEN; STRESS; UPREGULATION; ANIMAL; BACTERIAL CAPSULE; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; MICROBIOLOGY; MORTALITY; PATHOGENICITY; VIRULENCE; WISTAR RAT;

ANIMALS; BACTERIAL CAPSULES; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; GENE EXPRESSION; HUMANS; NEURAMINIDASE; RATS; RATS, WISTAR; SIALIC ACIDS; UP-REGULATION; VIRULENCE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; RATTUS;

EID: 77954586663     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.036145-0     Document Type: Article

References (45)

1. Achtman, M., Mercer, A., Kusećek, B., Pohl, A., Heuzenroeder, M., Aaronson, W., Sutton, A. & Silver, R. P. (1983). Six widespread bacterial clones among Escherichia coli K1 isolates. Infect Immun 39, 315-335. (Pubitemid 13212533)
2. Avery, O. T. & Dubos, R. (1931). The protective action of a specific enzyme against type III pneumococcus infection in mice. J Exp Med 54, 73-89.
3. Bhoj, V. G. & Chen, Z. J. (2009). Ubiquitylation in innate and adaptive immunity. Nature 458, 430-437.
4. Bonacorsi, S. & Bingen, E. (2005). Molecular epidemiology of Escherichia coli causing neonatal meningitis. Int J Med Microbiol 295, 373-381. (Pubitemid 41225452)
5. Bortolussi, R., Ferrieri, P. & Wannamaker, L. W. (1978). Dynamics of Escherichia coli infection and meningitis in infant rats. Infect Immun 22, 480-485. (Pubitemid 9052623)
6. Boyce, J. D., Wilkie, I., Harper, M., Paustian, M. L., Kapur, V. & Adler, B. (2002). Genomic scale analysis of Pasteurella multocida gene expression during growth within the natural chicken host. Infect Immun 70, 6871-6879. (Pubitemid 35387920)
7. Cegelski, L., Marshall, G. R., Eldridge, G. R. & Hultgren, S. J. (2008). The biology and future prospects of antivirulence therapies. Nat Rev Microbiol 6, 17-27. (Pubitemid 350286217)
8. Davidsen, T., Koomey, M. & Tønjum, T. (2007). Microbial genome dynamics in CNS pathogens. Neuroscience 145, 1375-1387. (Pubitemid 46602744)
9. Fernando, A. M. R., Heath, P. T. & Menson, E. N. (2008). Antimicrobial policies in the neonatal units of the United Kingdom and Republic of Ireland. J Antimicrob Chemother 61, 743-745. (Pubitemid 351321155)
10. Francis, T., Terrell, E. E., Dubos, R. & Avery, O. T. (1934). Experimental type III pneumococcus pneumonia in monkeys. II. Treatment with an enzyme which decomposes the specific capsular polysaccharide of pneumococcus type III. J Exp Med 59, 641-668.
11. Galiza, E. P. & Heath, P. T. (2009). Improving the outcome of neonatal meningitis. Curr Opin Infect Dis 22, 229-234.
12. Glode, M. P., Sutton, A., Moxon, E. R. & Robbins, J. B. (1977). Pathogenesis of neonatal Escherichia coli meningitis: induction of bacteremia and meningitis in infant rats fed E. coli K1. Infect Immun 16, 75-80. (Pubitemid 8086697)
13. Goodner, K., Dubos, R. & Avery, O. T. (1932). The action of a specific enzyme upon the dermal infection of rabbits with type III pneumococcus. J Exp Med 55, 393-404.
14. Gross, R. J., Cheasty, T. & Rowe, B. (1977). Isolation of bacteriophages specific for the K1 polysaccharide antigen of Escherichia coli. J Clin Microbiol 6, 548-550. (Pubitemid 8252853)
15. Harvey, D., Holt, D. E. & Bedford, H. (1999). Bacterial meningitis in the newborn: a prospective study of mortality and morbidity. Semin Perinatol 23, 218-225. (Pubitemid 29295802)
16. Inaba, Y., Ishiguro, A. & Shimbo, T. (1997). The production of macrophage inflammatory protein-1-a in the cerebrospinal fluid at the initial stage of meningitis in children. Pediatr Res 42, 788-793. (Pubitemid 27509537)
17. Kim, K. S., Itabashi, H., Gemski, P., Sadoff, J., Warren, R. L. & Cross, A. S. (1992). The K1 capsule is the critical determinant in the development of Escherichia coli meningitis in the rat. J Clin Invest 90, 897-905.
18. Leggate, D. R., Bryant, J. M., Redpath, M. B., Head, D., Taylor, P. W. & Luzio, J. P. (2002). Expression, mutagenesis and kinetic analysis of recombinant K1E endosialidase to define the site of proteolytic processing and requirements for catalysis. Mol Microbiol 44, 749-760. (Pubitemid 34526585)
19. Leib, S. L. & Täuber, M. G. (1999). Pathogenesis of bacterial meningitis. Infect Dis Clin North Am 13, 527-548.
20. Lein, E. S., Hawrylycz, M. J., Ao, N., Ayres, M., Bensinger, A., Bernard, A., Boe, A. F., Boguski, M. S., Brockway, K. S. & other authors (2007). Genome-wide atlas of gene expression in the adult mouse brain. Nature 445, 168-176. (Pubitemid 46095716)
21. Lyons, E. J., Amos, W., Berkley, J. A., Mwangi, I., Shafi, M., Williams, T. N., Newton, C. R., Peshu, N., Marsh, K. & other authors (2009). Homozygosity and risk of childhood death due to invasive bacterial disease. BMC Med Genet 10, 55.
22. May, M., Daley, A. J., Donath, S. & Isaacs, D. (2005). Early onset neonatal meningitis in Australia and New Zealand, 1992-2002. Arch Dis Child Fetal Neonatal Ed 90, F324-F327. (Pubitemid 40933396)
23. Moen, S. T., Yeager, L. A., Lawrence, W. S., Ponce, C., Galindo, C. L., Garner, H. R., Baze, W. B., Suarez, G., Peterson, J. W. & Chopra, A. K. (2008). Transcriptional profiling of murine organ genes in response to infection with Bacillus anthracis Ames spores. Microb Pathog 44, 293-310. (Pubitemid 351389743)
24. Møller, B., Morgensen, B. C., Wendelboe, P., Bendtzen, K. & Petersen, C. M. (1991). Bioactive and inactive forms of tumor necrosis factor-alpha in spinal fluid from patients with meningitis. J Infect Dis 163, 886-889.
25. Mushtaq, N., Redpath, M. B., Luzio, J. P. & Taylor, P. W. (2004). Prevention and cure of systemic Escherichia coli K1 infection by modification of the bacterial phenotype. Antimicrob Agents Chemother 48, 1503-1508. (Pubitemid 38544351)
26. Mushtaq, N., Redpath, M. B., Luzio, J. P. & Taylor, P. W. (2005). Treatment of experimental Escherichia coli infection with recombinant bacteriophage-derived capsule depolymerase. J Antimicrob Chemother 56, 160-165. (Pubitemid 41418351)
27. Mustafa, M. M., Mertsola, J., Ramilo, O., Sáez-Llorens, X., Risser, R. C. & McCracken, G. H. (1989). Increased endotoxin and interleukin-1 beta concentrations in cerebrospinal fluid of infants with coliform meningitis and ventriculitis associated with intraventricular gentamicin therapy. J Infect Dis 160, 891-895. (Pubitemid 19266848)
28. Nau, R. & Brück, W. (2002). Neuronal injury in bacterial meningitis: mechanisms and implications for therapy. Trends Neurosci 25, 38-45. (Pubitemid 34093784)
29. Polin, R. A. & Harris, M. C. (2001). Neonatal bacterial meningitis. Semin Neonatol 6, 157-172.
30. Ramilo, O., Sáez-Llorens, X., Mertsola, J., Jafari, H., Olsen, K. D., Hansen, E. J., Yoshinaga, M., Ohkawara, S., Nariuchi, H. & McCracken, G. H. (1990). Tumor necrosis factor alpha/cachectin and interleukin 1 beta initiate meningeal inflammation. J Exp Med 172, 497-507. (Pubitemid 20248391)
31. Reacher, M. H., Shah, A., Livermore, D. M., Wale, M. C. J., Graham, C., Johnson, A. P., Heine, H., Monnickendamm, M. A., Barker, K. F. & other authors (2000). Bacteraemia and antibiotic resistance of its pathogens reported in England and Wales between 1990 and 1998: trend analysis. BMJ 320, 213-216. (Pubitemid 30175735)
32. Robbins, J. B., McCracken, G. H., Gotschlich, E. C., Ørskov, F., Ørskov, I. & Hanson, L. A. (1974). Escherichia coli K1 polysaccharide associated with neonatal meningitis. N Engl J Med 290, 1216-1220.
33. Rutishauser, U. (2008). Polysialic acid in the plasticity of the developing and adult vertebrate nervous system. Nat Rev Neurosci 9, 26-35.
34. Scorpio, A., Chabot, D. J., Day, W. A., O'Brien, D. K., Vietri, N. J., Itoh, Y., Mohamadzadeh, M. & Friedlander, A. M. (2007). Poly-γ- glutamate capsule-degrading enzyme treatment enhances phagocytosis and killing of encapsulated Bacillus anthracis. Antimicrob Agents Chemother 51, 215-222. (Pubitemid 46047709)
35. Scorpio, A., Tobery, S. A., Ribot, W. J. & Friedlander, A. M. (2008). Treatment of experimental anthrax with recombinant capsule depolymerase. Antimicrob Agents Chemother 52, 1014-1020. (Pubitemid 351358382)
36. Shah, D. K., Daley, A. J., Hunt, R. W., Volpe, J. J. & Inder, T. E. (2005). Cerebral white matter injury in the newborn following Escherichia coli meningitis. Eur J Paediatr Neurol 9, 13-17.
37. Spanaus, K. S., Nadal, D., Pfister, H. W., Seebach, J., Widmer, U., Frei, K., Gloor, S. & Fontana, A. (1997). C-X-C and C-C chemokines are expressed in the cerebrospinal fluid in bacterial meningitis and mediate chemotactic activity on peripheral blood-derived polymorphonuclear and mononuclear cells in vitro. J Immunol 158, 1956-1964. (Pubitemid 127469556)
38. Sunil, V. R., Patel, K. J., Nilsen-Hamilton, M., Heck, D. E., Laskin, J. D. & Laskin, D. L. (2007). Acute endotoxemia is associated with upregulation of lipocalin 24p3/Lcn2 in lung and liver. Exp Mol Pathol 83, 177-187. (Pubitemid 47320654)
39. Täuber, M. G. & Moser, B. (1999). Cytokines and chemokines in meningeal inflammation: biology and clinical implications. Clin Infect Dis 28, 1-12. (Pubitemid 29246115)
40. Taylor, P. W., Bernal, P. & Zelmer, A. (2009). Modification of the bacterial phenotype as an approach to counter the emergence of multidrug-resistant pathogens. In Antibiotic Resistance: Causes and Risk Factors, Mechanisms and Alternatives, pp. 43-78. Edited by A. R. Bonilla & K. P. Muniz. Hauppauge, NY: Nova Science.
41. Tomlinson, S. & Taylor, P. W. (1985). Neuraminidase associated with coliphage E that specifically depolymerizes the Escherichia coli K1 capsular polysaccharide. J Virol 55, 374-378. (Pubitemid 16239724)
42. Tunkel, A. R. & Scheld, W. M. (1993). Pathogenesis and pathophysiology of bacterial meningitis. Clin Microbiol Rev 6, 118-136.
43. Woodall, C. A., Jones, M. A., Barrow, P. A., Hinds, J., Marsden, G. L., Kelly, D. J., Dorrell, N., Wren, B. W. & Maskell, D. J. (2005). Campylobacter jejuni gene expression in the chick cecum: evidence for adaptation to a low-oxygen environment. Infect Immun 73, 5278-5285. (Pubitemid 41105697)
44. Yadav, A., Malik, G. K., Trivedi, R., Prasad, A., Nath, K., Prasad, K. N., Agrawal, P., Rathore, R. K. S., Tripathi, R. P. & Gupta, R. K. (2009). Correlation of CSF neuroinflammatory molecules with leptomeningeal cortical subcortical white matter fractional anisotropy in neonatal meningitis. Magn Reson Imaging 27, 214-221.
45. Zelmer, A., Bowen, M., Jokilammi, A., Finne, J., Luzio, J. P. & Taylor, P. W. (2008). Differential expression of the polysialyl capsule during blood-to-brain transit of neuropathogenic Escherichia coli K1. Microbiology 154, 2522-2532.