Partially hydrolyzed 100% whey protein infant formula and atopic dermatitis risk reduction: A systematic review of the literature

Nutrition Reviews

Volumn 68, Issue 4, 2010, Pages 232-245

  Alexander, Dominik D ^a   Schmitt, Donald F ^b   Tran, Nga L ^a   Barraj, Leila M ^a   Cushing, Colleen A ^a  

^a EXPONENT INC   (United States)

^b Exponent Health Sciences Practice   (United States)

Author keywords

Allergy; Atopic dermatitis; Infant formula; Protein; Systematic review

Indexed keywords

MILK PROTEIN; WHEY PROTEIN;

ARTIFICIAL MILK; ATOPIC DERMATITIS; BREAST FEEDING; CLINICAL TRIAL; FOLLOW UP; HUMAN; INCIDENCE; MEDICAL LITERATURE; MILK; OUTCOME ASSESSMENT; REVIEW; RISK REDUCTION; SYSTEMATIC REVIEW; INFANT; NEWBORN; PROTEIN INTAKE; RISK FACTOR;

BREAST FEEDING; DERMATITIS, ATOPIC; DIETARY PROTEINS; HUMANS; INCIDENCE; INFANT; INFANT FORMULA; INFANT, NEWBORN; MILK PROTEINS; RISK FACTORS;

EID: 77954583939     PISSN: 00296643     EISSN: 17534887     Source Type: Journal    
DOI: 10.1111/j.1753-4887.2010.00281.x     Document Type: Review

References (45)

1. US Department of Health and Human Services and National Institute of Arthritis and Musculoskeletal and Skin Disease. Atopic Dermatitis. Bethesda, Maryland, National Institutes of Health. 2003. Report No.: NIH Publication No. 03-4272.
2. Greer FR, Sicherer SH, Burks AW. Effects of early nutritional interventions on the development of atopic disease in infants and children: The role of maternal dietary restriction, breastfeeding, timing of introduction of complementary foods, and hydrolyzed formulas. Pediatrics. 2008;121:183-191.
3. Leung DYM. Atopic Dermatitis. Nelson Textbook of Pediatrics, 18th ed. Philadelphia, PA: Saunders; 2007.
4. Moore MM, Rifas-Shiman SL, Rich-Edwards JW, et al. Perinatal predictors of atopic dermatitis occurring in the first six months of life. Pediatrics. 2004;113:468-474.
5. Bieber T. Atopic dermatitis. N Engl J Med. 2008;358:1483-1494.
6. Hahn EL, Bacharier LB. The atopic march: The pattern of allergic disease development in childhood. Immunol Allergy Clin North Am. 2005;25:231-246.
7. Eichenfield LF, Hanifin JM, Luger TA, Stevens SR, Pride HB. Consensus conference on pediatric atopic dermatitis. J Am Acad Dermatol. 2003;49:1088-1095.
8. Halken S, Host A. The lessons of noninterventional and interventional prospective studies on the development of atopic disease during childhood. Allergy. 2000;55:793-802.
9. Bergmann RL, Bergmann KE, Wahn U. Can we predict atopic disease using perinatal risk factors? Clin Exp Allergy. 1998;28:905-907.
10. Gdalevich M, Mimouni D, David M, Mimouni M. Breastfeeding and the onset of atopic dermatitis in childhood: A systematic review and meta-analysis of prospective studies. J Am Acad Dermatol. 2001;45:520-527.
11. Kull I, Bohme M, Wahlgren CF, Nordvall L, Pershagen G, Wickman M. Breast-feeding reduces the risk for childhood eczema. J Allergy Clin Immunol. 2005;116:657-661.
12. Kramer MS, Chalmers B, Hodnett ED, et al. Promotion of breastfeeding intervention trial (PROBIT): A randomized trial in the Republic of Belarus. JAMA. 2001;285:413-420.
13. Yang YW, Tsai CL, Lu CY. Exclusive breastfeeding and incident atopic dermatitis in childhood: A systematic review and metaanalysis of prospective cohort studies. Br J Dermatol. 2009;161:373-383.
14. Laubereau B, Brockow I, Zirngibl A, et al. Effect of breastfeeding on the development of atopic dermatitis during the first 3 years of life - results from the GINI-birth cohort study. J Pediatr. 2004;144:602-607.
15. Hays T, Wood RAA. Systematic review of the role of hydrolyzed infant formulas in allergy prevention. Arch Pediatr Adolesc Med. 2005;159:810-816.
16. von Berg A, Filipiak-Pittroff B, Kramer U, et al. Preventive effect of hydrolyzed infant formulas persists until age 6 years: Long-term results from the German Infant Nutritional Intervention Study (GINI). J Allergy Clin Immunol. 2008;121:1442-1447.
17. Han YS, Park HY, Ahn KM, Lee JS, Choi HM, Lee SI. Short-term effect of partially hydrolyzed formula on the prevention of development of atopic dermatitis in infants at high risk. J Korean Med Sci. 2003;18:547-551.
18. Oldaeus G, Anjou K, Bjorksten B, Moran JR, Kjellman NI. Extensively and partially hydrolysed infant formulas for allergy prophylaxis. Arch Dis Child. 1997;77:4-10.
19. Szajewska H,Mrukowicz JZ, Stoinska B, Prochowska A. Extensively and partially hydrolysed preterm formulas in the prevention of allergic diseases in preterm infants: A randomized, double-blind trial. Acta Paediatr. 2004;93:1159-1165.
20. Chandra RK. Five-year follow-up of high-risk infants with family history of allergy who were exclusively breast-fed or fed partial whey hydrolysate, soy, and conventional cow's milk formulas. J Pediatr Gastroenterol Nutr. 1997;24:380-388.
21. von Berg A, Koletzko S, Grubl A, et al. The effect of hydrolyzed cow's milk formula for allergy prevention in the first year of life: The German Infant Nutritional Intervention study, a randomized double-blind trial. J Allergy Clin Immunol. 2003;111:533-540.
22. Vandenplas Y, Hauser B, Van den Borre C, et al. The long-term effect of a partial whey hydrolysate formula on the prophylaxis of atopic disease. Eur J Pediatr. 1995;154:488-494.
23. Chan YH, Shek LP, Aw M, Quak SH, Lee BW. Use of hypoallergenic formula in the prevention of atopic disease among Asian children. J Paediatr Child Health. 2002;38:84-88.
24. Marini A, Agosti M, Motta G, Mosca F. Effects of a dietary and environmental prevention programme on the incidence of allergic symptoms in high atopic risk infants: Three years' follow-up. Acta Paediatr Suppl. 1996;414:1-21.
25. von Berg A, Koletzko S, Filipiak-Pittroff B, et al. Certain hydrolyzed formulas reduce the incidence of atopic dermatitis but not that of asthma: Three-year results of the German Infant Nutritional Intervention study. J Allergy Clin Immunol. 2007;119:718-725.
26. Vandenplas Y. Atopy at 3 years in high-risk infants fed whey hydrolysate or conventional formula. Lancet. 1992;339:1118.
27. Alexander DD, Cabana MD. Partially hydrolyzed 100% whey protein infant formula and reduced risk of atopic dermatitis: A meta-analysis. J Pediatr Gastroenterol Nutr. 2010;in press.
28. Chirico G, Gasparoni A, Ciardelli L, De Amici M, Colombo A, Rondini G. Immunogenicity and antigenicity of a partially hydrolyzed cow's milk infant formula. Allergy. 1997;52:82-88.
29. D'Agata A, Betta P, Sciacca P, et al. Role of dietary prevention in newborns at risk for atopy. Results of a follow-up study. Pediatr Med Chir. 1996;18:469-472.
30. de Seta L, Siani P, Cirillo G, Di Gruttola M, Cimaduomo L, Coletta S. The prevention of allergic diseases with a hypoallergenic formula: A follow-up at 24 months. The preliminary results. Pediatr Med Chir. 1994;16:251-254.
31. Vandenplas Y, Malfroot A, Dab I. Short-term prevention of cow's milk protein allergy in infants. Immunol Allergy Pract.1989;XI:430-437.
32. Vandenplas Y, Deneyer M, Sacre L, Loeb H. Preliminary data on a field study with a new hypo-allergic formula. Eur J Pediatr. 1988;148:274-277.
33. Willems R, Duchateau J, Magrez P, Denis R, Casimir G. Influence of hypoallergenic milk formula on the incidence of early allergic manifestations in infants predisposed to atopic diseases. Ann Allergy. 1993;71:147-150.
34. Tsai YT, Chou CC, Hsieh KH. The effect of hypoallergenic formula on the occurrence of allergic diseases in high risk infants. Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1991;32:137-144.
35. Becker A, Watson W, Ferguson A, Mich-Ward H, Chan-Yeung M. The Canadian asthma primary prevention study: Outcomes at 2 years of age. J Allergy Clin Immunol. 2004;113:650-656.
36. Chan-Yeung M, Manfreda J, Mich-Ward H, Ferguson A, Watson W, Becker AA. Randomized controlled study on the effectiveness of a multifaceted intervention program in the primary prevention of asthma in high-risk infants. Arch Pediatr Adolesc Med. 2000;154:657-663.
37. Exl BM, Deland U, Secretin MC, Preysch U, Wall M, Shmerling DH. Improved general health status in an unselected infant population following an allergen-reduced dietary intervention programme: The ZUFF-STUDYPROGRAMME. Part II: Infant growth and health status to age 6 months. ZUg-FrauenFeld. Eur J Nutr. 2000;39:145-156.
38. Exl BM, Deland U, Wall M, Preysch U, Secretin MC, Shmerling DH. Zug-frauenfeld nutritional survey ("zuff study"): Allergen-reduced nutrition in normal infant population and its health-related effects: Results at the age of six months. Nutr Res. 1998;18:1443-1462.
39. Osborn DA, Sinn J. Formulas containing hydrolysed protein for prevention of allergy and food intolerance in infants. Cochrane Database Syst Rev. 2006; issue 4, article no. CD003664.
40. Lam BCC, Yeung CY. The effect of breast milk, infant formula and hypoallergenic formula on incidence of atopic manifestation in high risk infants. Unpublished data; Nestle internal report; 1992.
41. Rzehak P, Sausenthaler S, Koletzko S, et al. Short- and longterm effects of feeding hydrolyzed protein infant formulas on growth at
42. Szajewska H, Albrecht P, Stoitiska B, Prochowska A, Gawecka A, Laskowska-Klita T. Extensive and partial protein hydrolysate preterm formulas: The effect on growth rate, protein metabolism indices, and plasma amino acid concentrations. J Pediatr Gastroenterol Nutr. 2001;32:303-309.
43. Mihatsch WA, Franz AR, Hogel J, Pohlandt F. Hydrolyzed protein accelerates feeding advancement in very low birth weight infants. Pediatrics. 2002;110:1199-1203.
44. Brenninkmeijer EE, Schram ME, Leeflang MM, Bos JD, Spuls PI. Diagnostic criteria for atopic dermatitis: A systematic review. BrJ Dermatol. 2008;158:754-765.
45. Wood RA. Prospects for the prevention of allergy: A losing battle or a battle still worth fighting? Arch Pediatr Adolesc Med. 2006;160:552-554.