메뉴 건너뛰기




Volumn 5, Issue 3, 2010, Pages 177-180

Lack of knowledge: Breast cancer and the soluble interleukin-6 receptor

Author keywords

Breast cancer; IL 6; SIL 6R; Transsignaling

Indexed keywords

CYTOKINE; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; SOLUBLE INTERLEUKIN 6 RECEPTOR; UNCLASSIFIED DRUG;

EID: 77954516047     PISSN: 16613791     EISSN: 16613805     Source Type: Journal    
DOI: 10.1159/000314248     Document Type: Review
Times cited : (11)

References (38)
  • 1
    • 33947414063 scopus 로고    scopus 로고
    • Significance of interleukin-6 (IL-6) in breast cancer (review)
    • Knüpfer H, Preiss R: Significance of interleukin-6 (IL-6) in breast cancer (review). Breast Cancer Res Treat 2007;102:129-135.
    • (2007) Breast Cancer Res Treat , vol.102 , pp. 129-135
    • Knüpfer, H.1    Preiss, R.2
  • 2
    • 0030890718 scopus 로고    scopus 로고
    • Gp130 and the interleukin-6 family of cytokines
    • Taga T, Kishimoto T: gp130 and the interleukin-6 family of cytokines. Annu Rev Immunol 1997;15: 797-819.
    • (1997) Annu Rev Immunol , vol.15 , pp. 797-819
    • Taga, T.1    Kishimoto, T.2
  • 3
    • 35648995976 scopus 로고    scopus 로고
    • Interleukin-6 and its receptor in cancer: Implications for translational therapeutics
    • Hong DS, Angelo LS, Kurzrock R: Interleukin-6 and its receptor in cancer: implications for translational therapeutics. Cancer 2007;110:1911-1928.
    • (2007) Cancer , vol.110 , pp. 1911-1928
    • Hong, D.S.1    Angelo, L.S.2    Kurzrock, R.3
  • 4
    • 0025831148 scopus 로고
    • The interleukin-6-dependent DNA-binding protein gene (transcription factor 5: TCF5) maps to human chromosome 20 and rat chromosome 3, the IL6 receptor locus (IL6R) to human chromosome 1 and rat chromosome 2, and the rat IL6 gene to rat chromosome 4
    • Szpirer J, Szpirer C, Riviere M, Houart C, Baumann M, Fey GH, Poli V, Cortese R, Islam MQ, Levan G: The interleukin-6-dependent DNA-binding protein gene (transcription factor 5: TCF5) maps to human chromosome 20 and rat chromosome 3, the IL6 receptor locus (IL6R) to human chromosome 1 and rat chromosome 2, and the rat IL6 gene to rat chromosome 4. Genomics 1991;10:539-546.
    • (1991) Genomics , vol.10 , pp. 539-546
    • Szpirer, J.1    Szpirer, C.2    Riviere, M.3    Houart, C.4    Baumann, M.5    Fey, G.H.6    Poli, V.7    Cortese, R.8    Islam, M.Q.9    Levan, G.10
  • 6
    • 27544476971 scopus 로고    scopus 로고
    • The role of IL-6 and STAT3 in inflammation and cancer
    • Hodge DR, Hurt EM, Farrar WL: The role of IL-6 and STAT3 in inflammation and cancer. Eur J Cancer 2005;41:2502-2512.
    • (2005) Eur J Cancer , vol.41 , pp. 2502-2512
    • Hodge, D.R.1    Hurt, E.M.2    Farrar, W.L.3
  • 9
    • 0026782577 scopus 로고
    • Complex of soluble human IL-6-receptor/ IL-6 up-regulates expression of acute-phase proteins
    • Mackiewicz A, Schooltink H, Heinrich PC, Rose- John S: Complex of soluble human IL-6-receptor/ IL-6 up-regulates expression of acute-phase proteins. J Immunol 1992;149:2021-2027.
    • (1992) J Immunol , vol.149 , pp. 2021-2027
    • MacKiewicz, A.1    Schooltink, H.2    Heinrich, P.C.3    Rose-John, S.4
  • 10
    • 2442605821 scopus 로고    scopus 로고
    • Interleukin-6 biology is coordinated by membrane bound and soluble receptors
    • Rose-John S: Interleukin-6 biology is coordinated by membrane bound and soluble receptors. Acta Biochim Pol 2003;50:603-611.
    • (2003) Acta Biochim Pol , vol.50 , pp. 603-611
    • Rose-John, S.1
  • 11
    • 0036772849 scopus 로고    scopus 로고
    • Gp130 stimulation and the maintenance of stem cells
    • Rose-John S: gp130 stimulation and the maintenance of stem cells. Trends Biotechnol 2002;20:417-419.
    • (2002) Trends Biotechnol , vol.20 , pp. 417-419
    • Rose-John, S.1
  • 12
    • 0032533949 scopus 로고    scopus 로고
    • Interleukin-6 and soluble interleukin-6 receptor: Direct stimulation of gp130 and hematopoiesis
    • Peters M, Muller AM, Rose-John S: Interleukin-6 and soluble interleukin-6 receptor: direct stimulation of gp130 and hematopoiesis. Blood 1998;92:3495-3504.
    • (1998) Blood , vol.92 , pp. 3495-3504
    • Peters, M.1    Muller, A.M.2    Rose-John, S.3
  • 14
    • 0032826994 scopus 로고    scopus 로고
    • Neural activities of IL-6-type cytokines often depend on soluble cytokine receptors
    • Marz P, Otten U, Rose-John S: Neural activities of IL-6-type cytokines often depend on soluble cytokine receptors. Eur J Neurosci 1999;11:2995-3004.
    • (1999) Eur J Neurosci , vol.11 , pp. 2995-3004
    • Marz, P.1    Otten, U.2    Rose-John, S.3
  • 15
    • 0032846613 scopus 로고    scopus 로고
    • Novel path to activation of vascular smooth muscle cells: Up-regulation of gp130 creates an autocrine activation loop by IL-6 and its soluble receptor
    • Klouche M, Bhakdi S, Hemmes M, Rose-John S: Novel path to activation of vascular smooth muscle cells: up-regulation of gp130 creates an autocrine activation loop by IL-6 and its soluble receptor. J Immunol 1999;163:4583-4589.
    • (1999) J Immunol , vol.163 , pp. 4583-4589
    • Klouche, M.1    Bhakdi, S.2    Hemmes, M.3    Rose-John, S.4
  • 18
    • 0031882207 scopus 로고    scopus 로고
    • Distinct classes of chaperoned IL-6 in human blood: Differential immunological and biological availability
    • Ndubuisi MI, Patel K, Rayanade RJ, Mittelman A, May LT, Sehgal PB: Distinct classes of chaperoned IL-6 in human blood: differential immunological and biological availability. J Immunol 1998;160:494-501.
    • (1998) J Immunol , vol.160 , pp. 494-501
    • Ndubuisi, M.I.1    Patel, K.2    Rayanade, R.J.3    Mittelman, A.4    May, L.T.5    Sehgal, P.B.6
  • 19
    • 0029863504 scopus 로고    scopus 로고
    • The function of the soluble interleukin 6 (IL-6) receptor in vivo: Sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6
    • Peters M, Jacobs S, Ehlers M, Vollmer P, Mullberg J, Wolf E, Brem G, Meyer zum Buschenfelde KH, Rose-John S: The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6. J Exp Med 1996;183:1399-1406.
    • (1996) J Exp Med , vol.183 , pp. 1399-1406
    • Peters, M.1    Jacobs, S.2    Ehlers, M.3    Vollmer, P.4    Mullberg, J.5    Wolf, E.6    Brem, G.7    Meyer Zum Buschenfelde, K.H.8    Rose-John, S.9
  • 20
    • 0037053394 scopus 로고    scopus 로고
    • Shedding of the interleukin-6 (IL-6) receptor (gp80) determines the ability of IL-6 to induce gp130 phosphorylation in human osteoblasts
    • Vermes C, Jacobs JJ, Zhang J, Firneisz G, Roebuck KA, Glant TT: Shedding of the interleukin-6 (IL-6) receptor (gp80) determines the ability of IL-6 to induce gp130 phosphorylation in human osteoblasts. J Biol Chem 2002;277:16879-16887.
    • (2002) J Biol Chem , vol.277 , pp. 16879-16887
    • Vermes, C.1    Jacobs, J.J.2    Zhang, J.3    Firneisz, G.4    Roebuck, K.A.5    Glant, T.T.6
  • 21
    • 0031471861 scopus 로고    scopus 로고
    • Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble interleukin-6 receptor alpha
    • Modur V, Li Y, Zimmerman GA, Prescott SM, McIntyre TM: Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble interleukin-6 receptor alpha. J Clin Invest 1997;100: 2752-2756.
    • (1997) J Clin Invest , vol.100 , pp. 2752-2756
    • Modur, V.1    Li, Y.2    Zimmerman, G.A.3    Prescott, S.M.4    McIntyre, T.M.5
  • 22
    • 0036160521 scopus 로고    scopus 로고
    • Preoperative plasma levels of interleukin-6 and its soluble receptor predict disease recurrence and survival of patients with bladder cancer
    • Andrews B, Shariat SF, Kim JH, Wheeler TM, Slawin KM, Lerner SP: Preoperative plasma levels of interleukin-6 and its soluble receptor predict disease recurrence and survival of patients with bladder cancer. J Urol 2002;167:1475-1481.
    • (2002) J Urol , vol.167 , pp. 1475-1481
    • Andrews, B.1    Shariat, S.F.2    Kim, J.H.3    Wheeler, T.M.4    Slawin, K.M.5    Lerner, S.P.6
  • 23
    • 1642392553 scopus 로고    scopus 로고
    • Association of pre- and postoperative plasma levels of transforming growth factor beta(1) and interleukin 6 and its soluble receptor with prostate cancer progression
    • Shariat SF, Kattan MW, Traxel E, Andrews B, Zhu K, Wheeler TM, Slawin KM: Association of pre- and postoperative plasma levels of transforming growth factor beta(1) and interleukin 6 and its soluble receptor with prostate cancer progression. Clin Cancer Res 2004;10:1992-1999.
    • (2004) Clin Cancer Res , vol.10 , pp. 1992-1999
    • Shariat, S.F.1    Kattan, M.W.2    Traxel, E.3    Andrews, B.4    Zhu, K.5    Wheeler, T.M.6    Slawin, K.M.7
  • 24
    • 0038351087 scopus 로고    scopus 로고
    • Relationship between circulating serum soluble interleukin-6 receptor and the angiogenic cytokines basic fibroblast growth factor and vascular endothelial growth factor in multiple myeloma
    • Alexandrakis MG, Passam FH, Boula A, Christophoridou A, Aloizos G, Roussou P, Kyriakou DS: Relationship between circulating serum soluble interleukin-6 receptor and the angiogenic cytokines basic fibroblast growth factor and vascular endothelial growth factor in multiple myeloma. Ann Hematol 2003;82:19-23.
    • (2003) Ann Hematol , vol.82 , pp. 19-23
    • Alexandrakis, M.G.1    Passam, F.H.2    Boula, A.3    Christophoridou, A.4    Aloizos, G.5    Roussou, P.6    Kyriakou, D.S.7
  • 25
    • 0032525085 scopus 로고    scopus 로고
    • The prognostic value of soluble interleukin-6 receptor in patients with multiple myeloma
    • Stasi R, Brunetti M, Parma A, Di Giulio C, Terzoli E, Pagano A: The prognostic value of soluble interleukin-6 receptor in patients with multiple myeloma. Cancer 1998;82:1860-1866.
    • (1998) Cancer , vol.82 , pp. 1860-1866
    • Stasi, R.1    Brunetti, M.2    Parma, A.3    Di Giulio, C.4    Terzoli, E.5    Pagano, A.6
  • 26
    • 0033501137 scopus 로고    scopus 로고
    • Serum levels of IL-6 type cytokines and soluble IL-6 receptors in active B-cell chronic lymphocytic leukemia and in cladribine induced remission
    • Robak T, Wierzbowska A, Blasinska-Morawiec M, Korycka A, Blonski JZ: Serum levels of IL-6 type cytokines and soluble IL-6 receptors in active B-cell chronic lymphocytic leukemia and in cladribine induced remission. Mediators Inflamm 1999;8:277-286.
    • (1999) Mediators Inflamm , vol.8 , pp. 277-286
    • Robak, T.1    Wierzbowska, A.2    Blasinska-Morawiec, M.3    Korycka, A.4    Blonski, J.Z.5
  • 28
    • 12344307362 scopus 로고    scopus 로고
    • The relationship between circulating concentrations of C-reactive protein, inflammatory cytokines and cytokine receptors in patients with non-small-cell lung cancer
    • McKeown DJ, Brown DJ, Kelly A, Wallace AM, McMillan DC: The relationship between circulating concentrations of C-reactive protein, inflammatory cytokines and cytokine receptors in patients with non-small-cell lung cancer. Br J Cancer 2004;91: 1993-1995.
    • (2004) Br J Cancer , vol.91 , pp. 1993-1995
    • McKeown, D.J.1    Brown, D.J.2    Kelly, A.3    Wallace, A.M.4    McMillan, D.C.5
  • 29
    • 0034456695 scopus 로고    scopus 로고
    • Relationship between circulating interleukin-10 (IL-10) with interleukin-6 (IL-6) type cytokines (IL-6, interleukin-11 (IL-11), oncostatin M (OSM)) and soluble interleukin-6 (IL-6) receptor (sIL-6R) in patients with multiple myeloma
    • Urbanska-Rys H, Wiersbowska A, Stepien H, Robak T: Relationship between circulating interleukin-10 (IL-10) with interleukin-6 (IL-6) type cytokines (IL-6, interleukin-11 (IL-11), oncostatin M (OSM)) and soluble interleukin-6 (IL-6) receptor (sIL-6R) in patients with multiple myeloma. Eur Cytokine Netw 2000;11:443-451.
    • (2000) Eur Cytokine Netw , vol.11 , pp. 443-451
    • Urbanska-Rys, H.1    Wiersbowska, A.2    Stepien, H.3    Robak, T.4
  • 30
    • 0032933715 scopus 로고    scopus 로고
    • Relationship of serum levels of interleukin-6, soluble interleukin-6 receptor and tumour necrosis factor receptors to the acute-phase protein response in advanced pancreatic cancer
    • Barber MD, Fearon KC, Ross JA: Relationship of serum levels of interleukin-6, soluble interleukin-6 receptor and tumour necrosis factor receptors to the acute-phase protein response in advanced pancreatic cancer. Clin Sci (Lond) 1999;96:83-87.
    • (1999) Clin Sci (Lond) , vol.96 , pp. 83-87
    • Barber, M.D.1    Fearon, K.C.2    Ross, J.A.3
  • 32
    • 1642330542 scopus 로고    scopus 로고
    • Changes in soluble IL-6 receptor and IL-6 production by polymorphonuclear cells and whole blood cells of breast cancer patients
    • Jablonska E, Pietruska Z: Changes in soluble IL-6 receptor and IL-6 production by polymorphonuclear cells and whole blood cells of breast cancer patients. Arch Immunol Ther Exp (Warsz) 1998;46:25-29.
    • (1998) Arch Immunol Ther Exp (Warsz) , vol.46 , pp. 25-29
    • Jablonska, E.1    Pietruska, Z.2
  • 33
    • 0032127276 scopus 로고    scopus 로고
    • Changes in sIL-6R and sTNF-Rs release by PMNs and the serum levels in breast cancer patients at different stages of treatment
    • Jablonska E: Changes in sIL-6R and sTNF-Rs release by PMNs and the serum levels in breast cancer patients at different stages of treatment. Cytokine 1998;10:540-543.
    • (1998) Cytokine , vol.10 , pp. 540-543
    • Jablonska, E.1
  • 35
    • 0034802899 scopus 로고    scopus 로고
    • Investigation of interleukin-6 (IL-6), soluble IL-6 receptor (sIL-6R) and soluble gp130 (sgp130) in sera of cancer patients
    • Kovacs E: Investigation of interleukin-6 (IL-6), soluble IL-6 receptor (sIL-6R) and soluble gp130 (sgp130) in sera of cancer patients. Biomed Pharmacother 2001;55:391-396.
    • (2001) Biomed Pharmacother , vol.55 , pp. 391-396
    • Kovacs, E.1
  • 36
    • 0028880991 scopus 로고
    • IL-6sR: Release from MCF-7 breast cancer cells and role in regulating peripheral oestrogen synthesis
    • Singh A, Purohit A, Wang DY, Duncan LJ, Ghilchik MW, Reed MJ: IL-6sR: release from MCF-7 breast cancer cells and role in regulating peripheral oestrogen synthesis. J Endocrinol 1995; 147:R9-R12.
    • (1995) J Endocrinol , vol.147
    • Singh, A.1    Purohit, A.2    Wang, D.Y.3    Duncan, L.J.4    Ghilchik, M.W.5    Reed, M.J.6
  • 37
    • 0029896751 scopus 로고    scopus 로고
    • A soluble interleukin 6 receptor isolated from conditioned medium of human breast cancer cells is encoded by a differentially spliced mRNA
    • Oh JW, Revel M, Chebath J: A soluble interleukin 6 receptor isolated from conditioned medium of human breast cancer cells is encoded by a differentially spliced mRNA. Cytokine 1996;8:401-409.
    • (1996) Cytokine , vol.8 , pp. 401-409
    • Oh, J.W.1    Revel, M.2    Chebath, J.3
  • 38
    • 0026483986 scopus 로고
    • Enhancement of interleukin 6 cytostatic effect on human breast carcinoma cells by soluble IL-6 receptor from urine and reversion by monoclonal antibody
    • Novick D, Shulman LM, Chen L, Revel M: Enhancement of interleukin 6 cytostatic effect on human breast carcinoma cells by soluble IL-6 receptor from urine and reversion by monoclonal antibody. Cytokine 1992;4:6-11.
    • (1992) Cytokine , vol.4 , pp. 6-11
    • Novick, D.1    Shulman, L.M.2    Chen, L.3    Revel, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.