Assortative human pair-bonding for partner ancestry and allelic variation of the dopamine receptor D4 (DRD4) gene

Social Cognitive and Affective Neuroscience

Volumn 5, Issue 2-3, 2009, Pages 194-202

  Eisenberg, Dan T A ^a   Apicella, Coren L ^b   Campbell, Benjamin C ^c   Dreber, Anna ^d,e   Garcia, Justin R ^f   Koji Lum, J ^f  

^a NORTHWESTERN UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

^c UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^d STOCKHOLM SCHOOL OF ECONOMICS   (Sweden)

^e HARVARD UNIVERSITY   (United States)

^f BINGHAMTON UNIVERSITY   (United States)

Author keywords

Ancestry; Assortative mating; DRD4; Pair bonds; Race

Indexed keywords

DNA; DOPAMINE 4 RECEPTOR; DRD4 PROTEIN, HUMAN;

ADOLESCENT; ADULT; ALLELE; ARTICLE; CULTURAL FACTOR; ETHNIC GROUP; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; HUMAN; MALE; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEXUAL BEHAVIOR; VARIABLE NUMBER OF TANDEM REPEAT;

ADOLESCENT; ALLELES; CROSS-CULTURAL COMPARISON; DNA; ETHNIC GROUPS; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; MALE; MINISATELLITE REPEATS; PAIR BOND; POLYMORPHISM, GENETIC; RECEPTORS, DOPAMINE D4; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; YOUNG ADULT;

EID: 77954500542     PISSN: 17495016     EISSN: 17495024     Source Type: Journal    
DOI: 10.1093/scan/nsp026     Document Type: Article

References (82)

1. Ahern, F.M., Johnson, R.C., Cole, R.E. (1983). Generational differences in spouse similarity in education attainment. Behavior Genetics, 13,95-8.
2. Apicella, C.L., Dreber, A., Campbell, B., Gray, P.B., Hoffman, M., Little, A.C. (2008). Testosterone and financial risk preferences. Evolution and Human Behavior, 29, 384-90.
3. Aragona, B.J., Liu, Y., Yu, Y.J., et al. (2006). Nucleus accumbens dopamine differentially mediates the formation and maintenance of monogamous pair bonds. Nature Neuroscience, 9, 133-9.
4. Asghari, V., Sanyal, S., Buchwaldt, S., Paterson, A., Jovanovic, V., Vantol, H.H.M. (1995). Modulation of intracellular cyclic-amp levels by different human dopamine D4 receptor variants. Journal of Neurochemistry, 65, 1157-65.
5. Asghari, V., Schoots, O., Vankats, S., et al. (1994). Dopamine D4 receptor repeatAdvP4D35B6.-1.C151analysis of different native and mutant forms of the human and rat genes. Molecular Pharmacology, 46, 364-73.
6. Beazely, M.A., Tong, A., Wei, W.L., Van Tol, H., Sidhu, B., MacDonald, J.F. (2006). D2-class dopamine receptor inhibition of NMDA currents in prefrontal cortical neurons is platelet-derived growth factor receptordependent. Journal of Neurochemistry, 98, 1657-63.
7. Blascovich, J., Mendes, W.B., Hunter, S.B., Lickel, B., Kowai-Bell, N. (2001). Perceiver threat in social interactions with stigmatized others. Journal of Personality and Social Psychology, 80, 253-67.
8. Boas, F. (1909). Race problems in America. Science, 29, 839-849.
9. Boom, R., Sol, C., Salimans, M., Jansen, C., Wertheim-van Dillen, P., van der Noordaa, J. (1990). Rapid and simple method for purification of nucleic acids. Journal of Clinical Microbiology, 28, 495-503.
10. Brody, A.L., Mandelkern, M.A., Olmstead, R.E., et al. (2006). Gene variants of brain dopamine pathways and smoking-induced dopamine release in the ventral caudate/nucleus accumbens. Archives of General Psychiatry, 63, 808-16.
11. Callier, S., Snapyan, M., Crom, S.L., Prou, D., Vincent, J.D., Vernier, P. (2003). Evolution and cell biology of dopamine receptors in vertebrates. Biology of the Cell, 95, 489-502.
12. Chen, C.S., Burton, M., Greenberger, E., Dmitrieva, J. (1999). Population migration and the variation of dopamine D4 receptor (DRD4) allele frequencies around the globe. Evolution and Human Behavior, 20, 309-24.
13. Cho, D.I., Beorn, S., Van Tol, H.H.M., Caron, M.G., Kim, K.M. (2006). Characterization of the desensitization properties of five dopamine receptor subtypes and alternatively spliced variants of dopamine D-2 and D-4 receptors. Biochemical and Biophysical Research Communications, 350, 634-40.
14. Ciani, A.S.C., Capiluppi, C., Veronese, A., Sartori, G. (2007). The adaptive value of personality differences revealed by small island population dynamics. European Journal of Personality, 21,3-22.
15. Cronk, L. (1999). That Complex Whole: Culture and the Evolution of Human Behavior. Boulder, CO: Westview Press.
16. Curtis, J.T., Wang, Z. (2005). Glucocorticoid receptor involvement in pair bonding in female prairie voles: the effects of acute blockade and interactions with central dopamine reward systems. Neuroscience, 134, 369-76.
17. Czermak, C., Lehofer, M., Liebmann, P.M., Traynor, J. (2006). [S-35]GTP gamma S binding at the human dopamine D4 receptor variants hD4.2, hD4.4 and hD4.7 following stimulation by dopamine, epinephrine and norepinephrine. European Journal of Pharmacology, 531,20-4.
18. Darwin, C. (1977). The Origin of Species and the Descent of Man. New York: Random House.
19. De la Garza, R., Madras, B.K. (2000). [H-3]PNU-101958, a D-4 dopamine receptor probe, accumulates in prefrontal cortex and hippocampus of non-human primate brain. Synapse, 37, 232-44.
20. Defagot, M.C., Antonelli, M.C. (1997). Autoradiographic localization of the putative D4 dopamine receptor in rat brain. Neurochemical Research, 22, 401-7.
21. Diamond, A. (2005). Attention-deficit disorder (attention-deficit/ hyperactivity disorder without hyperactivity): A neurobiologically and behaviorally distinct disorder from attention-deficit/hyperactivity disorder (with hyperactivity). Development and Psychopathology, 17, 807-25.
22. Ding, Y.C., Chi, H.C., Grady, D.L., et al. (2002). Evidence of positive selection acting at the human dopamine receptor D4 gene locus. Proceedings of the National Academy of the USA, 99, 309-14.
23. Dominguez, J.M., Hull, E.M. (2005). Dopamine, the medial preoptic area, and male sexual behavior. Physiology & Behavior, 86, 356-68.
24. Dreber, A., Apicella, C.L., Eisenberg, D.T.A., et al. (2009). The 7R polymorphism in the dopamine D4 receptor gene (DRD4) is associated with financial risk-taking in men. Evolution and Human Behavior, 30, 85-92.
25. Durston, S., Fossella, J.A., Casey, B.J., et al. (2005). Differential effects of DRD4 and DAT1 genotype on fronto-striatal gray matter volumes in a sample of subjects with attention deficit hyperactivity disorder, their unaffected siblings, and controls. Molecular Psychiatry, 10, 678-85.
26. Eisenberg, D.T.A., Campbell, B., Gray, P.B., Sorenson, M.D. (2008). Dopamine receptor genetic polymorphisms and body composition in undernourished pastoralists: an exploration of nutrition indices among nomadic and recently settled Ariaal men of northern Kenya. BMC Evolutionary Biology, 8.
27. Eisenberg, D.T.A., Campbell, B., MacKillop, J., et al. (2007). Polymorphisms in the dopamine D2 and D4 receptor genes and reproductive, sexual and life history behaviors. Evolutionary Psychology, 5, 696-715.
28. Eisenberg, D.T.A., MacKillop, J., Modi, M., et al. (2007). Examining impulsivity as an endophenotype using a behavioral approach: a DRD2 TaqI A and DRD4 48-bp VNTR association study. Behavioral and Brain Functions, 3(2).
29. Feigelson, H., Rodriguez, C., Robertson, A., et al. (2001). Determinants of DNA yield and quality from buccal cell samples collected with mouthwash. Cancer Epidemiology, Biomarkers & Prevention, 10, 1005-8.
30. Fisher, H., Aron, A., Brown, L.L. (2005). Romantic love: an fMRI study of a neural mechanism for mate choice. Journal of Comparative Neurology, 493,58-62.
31. Fisher, H.E. (2004). Why We Love: The Nature and Chemistry of Romantic Love. New York: Holt.
32. Gal, S. (1979). Peasant men can't get wives: language change and sex roles in a bilingual community. Language in Society, 7,1-16.
33. Gingrich, B., Liu, Y., Cascio, C., Wang, Z.X., Insel, T.R. (2000). Dopamine D2 receptors in the nucleus accumbens are important for social attachment in female prairie voles (Microtus ochrogaster). Behavioral Neuroscience, 114, 173-183.
34. Guo, G., Tong, Y.Y. (2006). Age at first sexual intercourse, genes, and social context: evidence from twins and the dopamine D4 receptor gene. Demography, 43, 747-69.
35. Guo, S.W., Thompson, E.A. (1992). Performing the exact test of Hardy-Weinberg proportion for multiple alleles. Biometrics, 48, 361-72.
36. Halpin, B., Chan, T.W. (2003). Educational homogamy in Ireland and Britain: trends and patterns. The British Journal of Sociology, 54, 473-95.
37. Hamarman, S., Fossella, J., Ulger, C., Brimacombe, M., Dermody, J. (2004). Dopamine receptor 4 (DRD4) 7-repeat allele predicts methylphenidate dose response in children with attention deficit hyperactivity disorder: a pharmacogenetic study. Journal of Child and Adolescent Psychopharmacology, 14, 564-74.
38. Hamer, D.H. (2002). Genetics of Sexual Behavior. In: Benjamin, J, Ebstein, R, Belmaker, R, editors. Molecular Genetics and the Human Personality. Washington, D.C.: American Psychiatric Publishing, p. 265.
39. Harris, T.M., Kalbfleisch, P.J. (2000). Interracial dating: the implications of race for initiating a romantic relationship. Howard Journal of Communications, 11,49-64.
40. Hosking, L., Lumsden, S., Lewis, K., et al. (2004). Detection of genotyping errors by Hardy-Weinberg equilibrium testing. European Journal of Human Genetics, 12, 395-9.
41. Hutchison, K.E., Ray, L., Sandman, E., et al. (2006). The effect of olanzapine on craving and alcohol consumption. Neuropsychopharmacology, 31, 1310-7.
42. Hutchison, K.E., Wooden, A., Swift, R.M., et al. (2003). Olanzapine reduces craving for alcohol: A DRD4 VNTR polymorphism by pharmacotherapy interaction. Neuropsychopharmacology, 28, 1882-8.
43. Johnson, R.C., Ahern, F.M., Cole, R.E. (1980). Secular change in degree of assortative mating for ability? Behavior Genetics, 10,1-8.
44. Jokela, M. (2009). Personality predicts migration within and between U.S. states. Journal of Research in Personality, 43,79-83.
45. Jokela, M., Elovainio, M., Kivimäki, M., Keltikangas-Järvinen, L. (2008). Temperament and migration patterns in Finland. Psychological Science, 19, 831-7.
46. Jovanovic, V., Guan, H.C., Van Tol, H.H.M. (1999). Comparative pharmacological and functional analysis of the human dopamine D-4.2 and D-4.10 receptor variants. Pharmacogenetics, 9, 561-8.
47. Kalmijn, M. (1998). Intermarriage and homogamy: causes, patterns, trends. Annual Review of Sociology, 24, 395-421.
48. Kluger, A.N., Siegfried, Z., Ebstein, R.P. (2002). A meta-analysis of the association between DRD4 polymorphism and novelty seeking. Molecular Psychiatry, 7, 712-7.
49. Kuhnen, C.M., Chiao, J.Y. (2009). Genetic determinants of financial risk taking. PLoS ONE, 4, e4362.
50. Lahti, R.A., Roberts, R.C., Tamminga, C.A. (1995). D-2-family receptor distribution in human postmortem tissue: an autoradiographic study. Neuroreport, 6, 2505-12.
51. Li, D., Sham, P.C., Owen, M.J., He, L. (2006). Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD). Human Molecular Genetics, 15, 2276-84.
52. Livingston, R.W., Drwecki, B.B. (2007). Why are some individuals not racially biased? Susceptibility to affective conditioning predicts nonprejudice toward blacks. Psychological Science, 18, 816-23.
53. Lucentini, (2004). Gene association studies typically wrong. Scientist, 18, 20.
54. Lum, J., Cann, R., Martinson, J., Jorde, L. (1998). Mitochondrial and nuclear genetic relationships among Pacific island and Asian populations. American Journal of Human Genetics, 63, 613-24.
55. Matsumoto, M., Hidaka, K., Tada, S., Tasaki, Y., Yamaguchi, T. (1996). Low levels of mRNA for dopamine D4 receptor in human cerebral cortex and striatum. Journal of Neurochemistry, 66, 915-9.
56. McGough, J., McCracken, J., Swanson, J., et al. (2006). Pharmacogenetics of methylphenidate response in preschoolers with ADHD. Journal of the American Academy of Child and Adolescent Psychiatry, 45, 1314-22.
57. Meador-Woodruff, J., Damask, S., Wang, J., Haroutunian, V., Davis, K., Watson, S. (1996). Dopamine receptor mRNA expression in human striatum and neocortex. Neuropsychopharmacology, 15,17-29.
58. Melis, M.R., Argiolas, A. (1995). Dopamine and sexual-behavior. Neuroscience and Biobehavioral Reviews, 19,19-38.
59. Melis, M.R., Succu, S., Sanna, F., et al. (2006). PIP3EA and PD-168077, two selective dopamine D4 receptor agonists, induce penile erection in male rats: site and mechanism of action in the brain. European Journal of Neuroscience, 24, 2021-30.
60. Miller, W.B., Pasta, D.J., MacMurray, J., Chiu, C., Wu, H., Comings, D.E. (1999). Dopamine receptor genes are associated with age at first sexual intercourse. Journal of Biosocial Science, 31,43-54.
61. Mulcrone, J., Kerwin, R.W. (1997). The regional pattern of D4 gene expression in human brain. Neuroscience Letters, 234, 147-50.
62. Nalls, M.A., Simon-Sanchez, J., Gibbs, J.R., et al. (2009). Measures of autozygosity in decline: globalization, urbanization, and its implications for medical genetics. PLoS Genetics, 5, e1000415.
63. Noain, D., Avale, M.E., Wedemeyer, C., Calvo, D., Peper, M., Rubinstein, M. (2006). Identification of brain neurons expressing the dopamine D4 receptor gene using BAC transgenic mice. European Journal of Neuroscience, 24, 2429-38.
64. Oak, J.N., Lavine, N., Tol, H.H.M.V. (2001). Dopamine D4 and D2L receptor stimulation of the mitogen-activated protein kinase pathway is dependent on trans-activation of the platelet-derived growth factor receptor. Molecular Pharmacology, 60,92-103.
65. Olsson, A., Ebert, J.P., Banaji, M.R., Phelps, E.A. (2005). The role of social groups in the persistence of learned fear. Science, 309, 785-7.
66. Peach, C., Mitchell, J.C. (1988). Marriage distance and ethnicity. In: MascieTaylor, C.G.N., Boyce, A.J., editors. Human Mating Patterns. New York: Cambridge University Press, p. 237.
67. Rebollo, I., Boomsma, D.I. (2007). Personality: possible effects of inbreeding depression on sensation seeking. European Journal of Personality, 21, 621-3.
68. Richerson, P.J., Boyd, R. (2005). Not By Genes Alone: How Culture Transformed Human Evolution. Chicago: University of Chicago Press.
69. Rosenberg, N.A., Mahajan, S., Ramachandran, S., Zhao, C., Pritchard, J.K., Feldman, M.W. (2005). Clines, clusters, and the effect of study design on the inference of human population structure. PLoS Genetics, 1, e70.
70. Savitz, J.B., Ramesar, R.S. (2004). Genetic variants implicated in personality: a review of the more promising candidates. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 131B,20-32.
71. Schinka, J.A., Letsch, E.A., Crawford, F.C. (2002). DRD4 and novelty seeking: results of meta-analyses. American Journal of Medical Genetics, 114, 643-8.
72. Schoots, O., Van Tol, H.H.M. (2003). The human dopamine D4 receptor repeat sequences modulate expression. Pharmacogenomics Journal, 3, 343-8.
73. Smeltzer, M.D., Curtis, J.T., Aragona, B.J., Wang, Z.X. (2006). Dopamine, oxytocin, and vasopressin receptor binding in the medial prefrontal cortex of monogamous and promiscuous voles. Neuroscience Letters, 394, 146-51.
74. Smits, J., Ultee, W., Lammers, J. (1998). Educational homogamy in 65 countries: an explanation of differences in openness using countrylevel explanatory variables. American Sociological Review, 63, 264-85.
75. Sober, E., Wilson, D.S. (1998). Unto Others: The Evolution and Psychology of Unselfish Behavior. Cambridge, MA: Harvard University Press.
76. Succu, S., Sanna, F., Melis, T., Boi, A., Argiolas, A., Melis, M.R. (2007). Stimulation of dopamine receptors in the paraventricular nucleus of the hypothalamus of male rats induces penile erection and increases extra-cellular dopamine in the nucleus accumbens: involvement of central oxytocin. Neuropharmacology, 52, 1034-43.
77. Van Craenenbroeck, K., Clark, S.D., Cox, M.J., Oak, J.N., Liu, F., Van Tol, H.H.M. (2005). Folding efficiency is rate-limiting in dopamine D4 receptor biogenesis. Journal of Biological Chemistry, 280, 19350-7.
78. Van Tol, H.H.M., Wu, C.M., Guan, H-C., et al. (1992). Multiple dopamine D4 receptor variants in the human population. Nature, 358, 149-52.
79. Wang, E., Ding, Y.C., Flodman, P., et al. (2004). The genetic architecture of selection at the human dopamine receptor D4 (DRD4) gene locus. American Journal of Human Genetics, 74, 931-44.
80. Watts, V.J., Vu, M.N., Wiens, B.L., Jovanovic, V., Tol, H.H.M.V., Neve, K.A. (1999). Shortand long-term heterologous sensitization of adenylate cyclase by D4 dopamine receptors. Psychopharmacology, 141,84-92.
81. Zhang, K.H., Tarazi, F.I., Davids, E., Baldessarini, R.J. (2002). Plasticity of dopamine D-4 receptors in rat forebrain: temporal association with motor hyperactivity following neonatal 6-hydroxydopamine lesioning. Neuropsychopharmacology, 26, 625-33.
82. Zion, I.B., Tessler, R., Cohen, L., et al. (2006). Polymorphisms in the dopamine D4 receptor gene (DRD4) contribute to individual differences in human sexual behavior: desire, arousal and sexual function. Molecular Psychiatry,1-5.