The in situ and in vivo study on enhancing effect of borneol in nasal absorption of Geniposide in rats

Archives of Pharmacal Research

Volumn 33, Issue 5, 2010, Pages 691-696

  Lu, Yang ^a   Chen, Xiaolan ^a,b   Du, Shouying ^a   Wu, Qing ^a   Yao, Zongling ^a   Zhai, Yongsong ^a  

^a BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b GUIYANG COLLEGE OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Borneol; Enhancement; Geniposide; Nasal absorption; Pharmacokinetics

Indexed keywords

BORNEOL; GARDENIA EXTRACT; GENIPOSIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIFFUSION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG EFFECT; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; NOSE MUCOSA; PERFUSION; RAT; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; WATER ABSORPTION;

ABSORPTION; ADMINISTRATION, INTRANASAL; ANIMALS; BORNANES; DRUG INTERACTIONS; INJECTIONS, INTRAVENOUS; IRIDOIDS; MALE; NASAL MUCOSA; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77954476800     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-010-0507-8     Document Type: Article

References (20)

1. Z. Cai S. Hou Y. Li B. Zhao Z. Yang S. Xu J. Pu 2008 Effect of borneol on the distribution of gastrodin to the brain in mice via oral administration J. Drug Target. 16 178 184 10.1080/10611860701794395 1:CAS:528:DC%2BD1cXhvVenu7s%3D 18274938 (Pubitemid 351266554)
2. M. D. Chavanpatil P. R. Vavia 2004 The influence of absorption enhancers on nasal absorption of acyclovir Eur. J. Pharm. Biopharm. 57 483 487 10.1016/j.ejpb.2004.01.001 1:CAS:528:DC%2BD2cXjt1ShtLs%3D 15093597 (Pubitemid 38490566)
3. Y. M. Chen N. S. Wang 2004 Effect of borneol on the intercellular tight junction and pinocytosis vesicles in vitro blood-brain barrier model Zhongguo Zhong Xi Yi Jie He Za Zhi 24 632 634 15307705
4. X. Chen J. Zhu W. Sun L. Zhang 2006 Effect of Absorption enhancer of borneol on ginsenoside Rg1 and the nasal ciliotoxicity Acta Pharmacol. Sin. 41 261 264 1:CAS:528:DC%2BD2sXltFKjurc%3D (Pubitemid 44734810)
5. J. P. Dai J. Chen Y. F. Bei B. X. Han S. Wang 2009 Influence of borneol on primary mice oral fibroblasts: A penetration enhancer may be used in oral submucous fibrosis J. Oral. Pathol. Med. 38 276 281 1:CAS:528: DC%2BD1MXkt12nsrs%3D 19267840
6. D. Duchìne G. Ponchel 1993 Nasal administration: A tool of tomorrow's systemic administration of drug Drug Dev. Ind. Pharm. 19 101 122 10.3109/03639049309038763
7. M. Hayashi T. Hirasawa T. Muraoka 1983 Tetradine and isotetradine; two bisbenzyl tetra hydroisoquinoline alkaloids from merispemaceae with rat uterine smooth muscle relaxant activity Chem. Pharm. Bull. 33 2149 2152
8. S. Hirai T. Yashiki T. Matsuzawa 1981 Absorption of drugs from the nasal mucosa Int. J. Pharm. 7 317 325 10.1016/0378-5173(81)90058-2 1:CAS:528:DyaL3MXhvVSmu78%3D (Pubitemid 11158883)
9. C. H. Huang R. Kimura R. B. Nassar A. Hussain 1985 Mechanism of nasal absorption of drug I. Physicochemical parameters influencing the rate of in situ nasal absorption of drugs in rats J. Pharm. Sci. 74 608 611 10.1002/jps.2600740605 1:CAS:528:DyaL2MXks1Cgtrc%3D 4020646 (Pubitemid 15042119)
10. L. Illum 2000 Transport of drugs from the nasal cavity to the central nervous system Eur. J. Pharm. Sci. 11 1 18 10.1016/S0928-0987(00)00087-7 1:CAS:528:DC%2BD3cXksFektLo%3D 10913748 (Pubitemid 30410839)
11. H.-J. Koo K.-H. Lim H.-J. Jung E.-H. Park 2006 Anti-inflammatory evaluation of gardenia extract geniposide and genipin J. Ethnopharmacol. 103 496 500 10.1016/j.jep.2005.08.011 1:CAS:528:DC%2BD28XovVSqtA%3D%3D 16169698 (Pubitemid 43143390)
12. F. Li J. Feng Q. Cheng W. Zhu Y. Jin 2007 Delivery of 125I-cobrotoxin after intranasal administration to the brain: A microdialysis study in freely moving rats Int. J. Pharm. 328 161 167 10.1016/j.ijpharm.2006.08.011 1:CAS:528:DC%2BD28XhtlWqurbP 17049426 (Pubitemid 44880574)
13. F. W. H. M. Merkus N. G. M. Schipper J. C. Verhoef 1996 The influence of absorption enhancers on intranasal insulin absorption in normal and diabetic subjects J. Control. Release 41 69 75 10.1016/0168-3659(96)01357-0 1:CAS:528:DyaK28XltVOksbs%3D (Pubitemid 26246364)
14. J. C. Olivier M. Djilani S. Fahmy W. Couet 2001 In situ nasal absorption of midazolam in rats Int. J. Pharm. 213 187 192 10.1016/S0378-5173(00)00668-2 1:CAS:528:DC%2BD3MXmvFOjsA%3D%3D 11165106 (Pubitemid 32119474)
15. Y. Suzuki K. Kondo Y. Ikeda K. Umemura 2001 Antithrombotic effect of geniposide and genipin in the mouse thrombosis model Planta Med. 67 807 810 10.1055/s-2001-18842 1:CAS:528:DC%2BD38XjtV2lsQ%3D%3D 11745015 (Pubitemid 34015542)
16. K. Ueno Y. Takeda Y. Iwasaki F. Yoshizaki 2001 Simultaneous estimation of geniposide and genipin in mouse plasma using high-performance liquid chromatography Anal. Sci. 17 1237 1239 10.2116/analsci.17.1237 1:CAS:528:DC%2BD3MXotVSit7k%3D 11990605 (Pubitemid 33042995)
17. Y. Y. Xiao Q. N. Ping Z. P. Chen 2007 The enhancing effect of synthetical borneol on the absorption of tetramethylpyrazine phosphate in mouse Int. J. Pharm. 337 74 79 10.1016/j.ijpharm.2006.12.034 1:CAS:528:DC%2BD2sXlsFagsbw%3D (Pubitemid 46756038)
18. C. Yang H. Gao A. K. Mitra 2001 Chemical stability, enzymatic hydrolysis and nasal uptake of amino acid ester prodrugs of acyclovir J. Pharm. Sci. 90 617 624 10.1002/1520-6017(200105)90:5<617::AID-JPS1018>3.0.CO;2-5 1:CAS:528:DC%2BD3MXjt1OlsLo%3D 11288106 (Pubitemid 32378383)
19. G. Ye H. Y. Zhu H. L. Zhao B. Xu C. G. Huang 2006 HPLC method for the determination and pharmacokinetic studies on geniposide in rat serum after oral administration of traditional Chinese medicinal preparation Yin-Zhi-Ku decoction Biomed. Chromatogr. 20 743 747 10.1002/bmc.590 1:CAS:528:DC%2BD28Xot1Krt7k%3D 16235204 (Pubitemid 44203168)
20. Q. Zhang S. Du Y. Lu X. Yao 2009 Studies on O/W partition coefficient and absorption kinetics of geniposide in fructus gardeniae extract in rat intestine Zhongguo Zhong Yao Za Zhi 34 1840 1844 1:CAS:528:DC%2BD1MXhsVeit7nI 19894521