SCOPUS 정보 검색 플랫폼

Journal of Pharmaceutical Sciences

Volumn 90, Issue 5, 2001, Pages 617-624

Chemical stability, enzymatic hydrolysis, and nasal uptake of amino acid ester prodrugs of acyclovir

(3) Yang, Chun a Gao, Hongwu a Mitra, Ashim K a

a UNIVERSITY OF MISSOURI KANSAS CITY (United States)

Author keywords

Active transport; Acyclovir; Amino acid transporter; Nasal drug delivery; Peptide transporter; Prodrug

Indexed keywords

ACICLOVIR; ACICLOVIR DERIVATIVE; ASPARAGINE; ESTER; ESTERASE; GLYCYLSARCOSINE; PHOSPHATE; PRODRUG;

ANIMAL EXPERIMENT; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG HALF LIFE; DRUG STABILITY; DRUG SYNTHESIS; DRUG UPTAKE; HYDROLYSIS; NONHUMAN; NOSE; PH; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TEMPERATURE;

EID: 0035042563 PISSN: 00223549 EISSN: None Source Type: Journal
DOI: 10.1002/1520-6017(200105)90:5<617::AID-JPS1018>3.0.CO;2-5 Document Type: Article

Times cited : (52)

References (22)

1
- 0032484626
- Intranasal drug delivery
- (1998) Adv Drug Delivery Rev , vol.29 , pp. 39-49
- Hussain, A.A.¹

2
- 0032484671
- Prodrugs for nasal drug delivery
- (1998) Adv Drug Delivery Rev , vol.29 , pp. 135-146
- Krishamoorthy, R.¹ Mitra, A.K.²

3
- 0028316205
- The physicochemical properties, plasma enzymatic hydrolysis, and nasal absorption of acyclovir and its 2'-ester prodrugs
- (1994) Pharm Res , vol.11 , pp. 237-242
- Shao, Z.¹ Park, G.B.² Krishnamoorthy, R.³ Mitra, A.K.⁴

4
- 0024599205
- Acyclovir. An updated review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy
- (1989) Drug , vol.37 , pp. 233-309
- O'Brien, J.J.¹ Campoli-Richards, D.M.²

5
- 0028267246
- Bile salt-fatty acid mixed micelles as nasal absorption promoters: III. Effects on nasal transport and enzymatic degradation of acyclovir prodrugs
- (1994) Int J Pharm , vol.11 , pp. 243-250
- Shao, Z.¹ Mitra, A.K.²

6
- 0031690410
- Transbuccal delivery of acyclovir: In vitro determination of routes of buccal transport
- (1998) Pharm Res , vol.15 , pp. 1182-1188
- Shojaei, A.H.¹ Berner, B.² Li, X.³

7
- 0023720737
- Transport of tyrosine and phenyalanine across the rat nasal mucosa
- (1988) Life Sci , vol.43 , pp. 585-593
- Tengamnuay, P.¹ Mitra, A.K.²

8
- 85001736015
- Ph.D. Thesis, Purdue University, West Lafayette, IN
- (1989)
- Tengamnuay, P.¹

9
- 4244175718
- An electrogenic amino acid transporter in the apical membrane of cultured human bronchial epithelial cells
- (1998) Am J Physiol , vol.275 , pp. L917-L923
- Galietta, L.J.V.¹ Musante, L.² Romio, L.³ Caruso, U.⁴ Fantasia, A.⁵ Gazzolo, A.⁶ Romano, L.⁷ Sacco, O.⁸ Rossi, G.A.⁹ Varesio, L.¹⁰ Zegarra-Moran, O.¹¹

10
- 0026596218
- Amino acid ester prodrugs of acyclovir
- (1992) Antiviral Chem Chemother , vol.3 , pp. 157-164
- Beauchamp, L.M.¹ Orr, G.F.² De Miranda, P.³ Burnette, T.⁴ Krenitsky, T.A.⁵

11
- 0019496047
- Absorption of drugs from the nasal mucosa
- (1981) Int J Pharm , vol.7 , pp. 317-325
- Hirai, S.¹ Yashiki, T.² Matsuzawa, T.³ Mima, H.⁴

12
- 0021847759
- Mechanism of nasal absorption of drugs I: Physicochemical parameters influencing the rate of in situ nasal absorption of drugs in rats
- (1985) J Pharm Sci , vol.74 , pp. 608-611
- Huang, C.H.¹ Kimura, R.² Bawarshi-Nassar, R.³ Hussain, A.⁴

13
- 0032853619
- Intestinal peptide transport systems and oral drug availability
- (1999) Pharm Res , vol.16 , pp. 1331-1343
- Yang, C.Y.¹ Dantzig, A.H.² Pidgeon, C.³

14
- 0031662109
- 5'-Amino acid ester of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter
- (1998) Pharm Res , vol.15 , pp. 1154-1159
- Han, H.K.¹ Devrueh, R.L.A.² Rhie, J.K.³ Covitz, K.M.Y.⁴ Smith, P.L.⁵ Lee, C.P.⁶ Oh, D.M.⁷ Sadee, W.⁸ Amidon, G.L.⁹

15
- 0032916827
- Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line
- (1999) J Pharmacol Exp Ther , vol.289 , pp. 448-454
- Guo, A.L.¹ Hu, P.D.² Balimane, P.V.³ Leibach, F.H.⁴ Sinko, P.J.⁵

16
- 0032897670
- Synthesis, stability, and pharmacological evaluation of nipecotic acid prodrugs
- (1999) J Pharm Sci , vol.88 , pp. 561-567
- Bonina, F.P.¹ Arenare, L.² Palagiano, F.³ Saija, A.⁴ Nava, F.⁵ Trometta, D.⁶ De Caprariis, P.⁷

17
- 0028299081
- Drug delivery via active transport at the blood-brain barrier: Affinity of a prodrug of phosphono-formate for the large amino acid transporter
- (1994) Int J Pharm , vol.104 , pp. 157-167
- Walker, I.¹ Nicholls, D.² Irwin, W.J.³ Freeman, S.⁴

18
- 0032961331
- Evidence for overlapping substrate specificity between large neutral amino acid (LNAA) and dipeptide (hPEPT1) transporters for PD 158473, an NMDA antagonist
- (1999) Pharm Res , vol.16 , pp. 391-395
- Surendram, N.¹ Covitz, K.Y.² Han, H.³ Sadee, W.⁴ Oh, D.⁵ Amidon, G.L.⁶ Williamson, R.M.⁷ Bigge, C.F.⁸ Stewart, B.H.⁹

19
- 0004999419
- manuscript in preparation
- (2000) Mechanistic study on nasal absorption of amino acid ester prodrug of acyclovir: Competitive inhibition of L-tyrosine uptake by L-aspartic acid β-ester of acyclovir
- Yang, C.¹ Mitra, A.K.²

20
- 85001645708
- Nasal absorption of tyrosine linked model compounds
- in press
- (2000) J Pharm Sci
- Yang, C.¹ Mitra, A.K.²

21
- 0000273754
- Intestinal transport of amino acids and peptides
- Johnson, LR, Editor. New York: Raven Press
- (1994) rd ed. , pp. 1773-1794
- Ganapathy, V.¹ Brandsch, M.² Leibach, F.H.³

22
- 85001722874
- 2]-Kyotorphin
- (1990) Pharm Res , vol.7 , pp. 129-135
- Tengamnuay, P.¹ Mitra, A.K.²

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.