-
2
-
-
0015326584
-
Cardiopulmonary effects of antimalarial drugs. VI. Adenosine, quinacrine and primaquine
-
10.1016/0041-008X(72)90004-X 1:CAS:528:DyaE38XktFCju7w%3D 5047047
-
S. W. Bass M. A. Ramirez D. M. Aviado 1972 Cardiopulmonary effects of antimalarial drugs. VI. Adenosine, quinacrine and primaquine Toxicol. Appl. Pharmacol. 21 464 481 10.1016/0041-008X(72)90004-X 1:CAS:528:DyaE38XktFCju7w%3D 5047047
-
(1972)
Toxicol. Appl. Pharmacol.
, vol.21
, pp. 464-481
-
-
Bass, S.W.1
Ramirez, M.A.2
Aviado, D.M.3
-
3
-
-
0028914969
-
A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome
-
10.1016/0092-8674(95)90358-5 1:CAS:528:DyaK2MXksVahsL4%3D 7889573
-
M. E. Curran I. Splawski K. W. Timothy G. M. Vincent E. D. Green M. T. Keating 1995 A molecular basis for cardiac arrhythmia: hERG mutations cause long QT syndrome Cell 80 795 803 10.1016/0092-8674(95)90358-5 1:CAS:528: DyaK2MXksVahsL4%3D 7889573
-
(1995)
Cell
, vol.80
, pp. 795-803
-
-
Curran, M.E.1
Splawski, I.2
Timothy, K.W.3
Vincent, G.M.4
Green, E.D.5
Keating, M.T.6
-
4
-
-
0031985216
-
Quinidine
-
DOI 10.1056/NEJM199801013380107
-
A. A. Grace A. J. Camm 1998 Quinidine N. Engl. J. Med. 338 35 45 10.1056/NEJM199801013380107 1:CAS:528:DyaK1cXltVyitQ%3D%3D 9414330 (Pubitemid 28040538)
-
(1998)
New England Journal of Medicine
, vol.338
, Issue.1
, pp. 35-45
-
-
Grace, A.A.1
Camm, A.J.2
-
5
-
-
0027180607
-
Restrictive cardiomyopathy caused by chloroquine
-
10.1136/hrt.69.5.451 1:STN:280:DyaK3s3pvVCqsA%3D%3D 8518071
-
G. Iglesias-cubero J. J. Rodriguez-reguero J. M. Rojo-ortega 1993 Restrictive cardiomyopathy caused by chloroquine Br. Heart J. 69 451 452 10.1136/hrt.69.5.451 1:STN:280:DyaK3s3pvVCqsA%3D%3D 8518071
-
(1993)
Br. Heart J.
, vol.69
, pp. 451-452
-
-
Iglesias-Cubero, G.1
Rodriguez-Reguero, J.J.2
Rojo-Ortega, J.M.3
-
6
-
-
0033952902
-
Molecular determinant of high-affinity dofetilide binding to hERG1 expressed in Xenopus oocytes: Involvement of S6 sites
-
1:CAS:528:DC%2BD3cXhtVakt7g%3D 10648647
-
J. P. Lees-Miller Y. Duan G. Q. Teng H. J. Duff 2000 Molecular determinant of high-affinity dofetilide binding to hERG1 expressed in Xenopus oocytes: involvement of S6 sites Mol. Pharmacol. 57 367 374 1:CAS:528: DC%2BD3cXhtVakt7g%3D 10648647
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 367-374
-
-
Lees-Miller, J.P.1
Duan, Y.2
Teng, G.Q.3
Duff, H.J.4
-
7
-
-
0034710933
-
A structural basis for drug-induced long QT syndrome
-
10.1073/pnas.210244497 1:CAS:528:DC%2BD3cXnvVSnsro%3D 11005845
-
J. S. Mitcheson J. Chen M. Lin C. Culberson M. C. Sanguinetti 2000 A structural basis for drug-induced long QT syndrome Proc. Natl. Acad. Sci. U S A 97 12329 12333 10.1073/pnas.210244497 1:CAS:528:DC%2BD3cXnvVSnsro%3D 11005845
-
(2000)
Proc. Natl. Acad. Sci. U S A
, vol.97
, pp. 12329-12333
-
-
Mitcheson, J.S.1
Chen, J.2
Lin, M.3
Culberson, C.4
Sanguinetti, M.C.5
-
8
-
-
0036190690
-
Inhibition of cardiac Na+ current by primaquine
-
10.1038/sj.bjp.0704460 1:CAS:528:DC%2BD38XhvVejsbk%3D 11834623
-
G. Orta-Salazar R. A. Bouchard F. Morales-Salgado E. M. Salinas-Stefanon 2002 Inhibition of cardiac Na+ current by primaquine Br. J. Pharmacol. 135 751 763 10.1038/sj.bjp.0704460 1:CAS:528:DC%2BD38XhvVejsbk%3D 11834623
-
(2002)
Br. J. Pharmacol.
, vol.135
, pp. 751-763
-
-
Orta-Salazar, G.1
Bouchard, R.A.2
Morales-Salgado, F.3
Salinas-Stefanon, E.M.4
-
9
-
-
33845512496
-
Antimicrobial-associated QT interval prolongation: Pointes of interest
-
DOI 10.1086/508873
-
R. C. Owens Jr. T. D. Nolin 2006 Antimicrobial-associated QT interval prolongation: pointes of interest Clin. Infect. Dis. 43 1603 1611 10.1086/508873 1:CAS:528:DC%2BD2sXislWjsw%3D%3D 17109296 (Pubitemid 44910994)
-
(2006)
Clinical Infectious Diseases
, vol.43
, Issue.12
, pp. 1603-1611
-
-
Owens Jr., R.C.1
Nolin, T.D.2
-
10
-
-
0344492207
-
Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: Evidence for a provisional safety margin in drug development
-
DOI 10.1016/S0008-6363(02)00846-5
-
W. Redfern L. Carlsson A. Davis W. Lynch I. MacKenzie S. Palethorpe P. Siegl I. Strang A. Sullivan R. Wallis A. Camm T. Hammond 2003 Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development Cardiovasc. Res. 58 32 45 10.1016/S0008- 6363(02)00846-5 1:CAS:528:DC%2BD3sXit12gsb8%3D 12667944 (Pubitemid 36351620)
-
(2003)
Cardiovascular Research
, vol.58
, Issue.1
, pp. 32-45
-
-
Redfern, W.S.1
Carlsson, L.2
Davis, A.S.3
Lynch, W.G.4
MacKenzie, I.5
Palethorpe, S.6
Siegl, P.K.S.7
Strang, I.8
Sullivan, A.T.9
Wallis, R.10
Camm, A.J.11
Hammond, T.G.12
-
11
-
-
0025351245
-
+ current. Differential sensitivity to block by class III antiarrhythmic agent
-
DOI 10.1085/jgp.96.1.195
-
M. C. Sanguinetti N. K. Jurkiewicz 1990 Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents J. Gen. Physiol. 96 195 215 10.1085/jgp.96.1.195 1:CAS:528:DyaK3cXls1Gitbo%3D 2170562 (Pubitemid 20227082)
-
(1990)
Journal of General Physiology
, vol.96
, Issue.1
, pp. 195-215
-
-
Sanguinetti, M.C.1
Jurkiewicz, N.K.2
-
12
-
-
0032970148
-
Dysfunction of delayed rectifier potassium channels in an inherited cardiac arrhythmia
-
DOI 10.1111/j.1749-6632.1999.tb11302.x
-
M. C. Sanguinetti 1999 Dysfunction of delayed rectifier potassium channels in an inherited cardiac arrhythmia Ann. N. Y. Acad. Sci. 868 406 413 10.1111/j.1749-6632.1999.tb11302.x 1:CAS:528:DyaK1MXjvFKitb0%3D 10414310 (Pubitemid 29281141)
-
(1999)
Annals of the New York Academy of Sciences
, vol.868
, pp. 406-413
-
-
Sanguinetti, M.C.1
-
13
-
-
26944438354
-
Drugs, QTc interval prolongation and final ICH E14 guideline: An important milestone with challenges ahead
-
DOI 10.2165/00002018-200528110-00003
-
R. R. Shah 2005 Drugs, QTc interval prolongation and final ICH E14 guideline: an important milestone with challenges ahead Drug Saf. 28 1009 1028 10.2165/00002018-200528110-00003 1:CAS:528:DC%2BD2MXhtlWhtb%2FP 16231954 (Pubitemid 41483706)
-
(2005)
Drug Safety
, vol.28
, Issue.11
, pp. 1009-1028
-
-
Shah, R.R.1
-
14
-
-
0030058762
-
Class III antiarrhymic drugs block hERG, a human cardiac delayed rectifier K+ channel. Open-channel block by methanesulfonanilides
-
1:CAS:528:DyaK28XhtlWrt7Y%3D 8593709
-
P. S. Spector M. E. Curran M. T. Keating 1996 Class III antiarrhymic drugs block hERG, a human cardiac delayed rectifier K+ channel. Open-channel block by methanesulfonanilides Circ. Res. 78 499 503 1:CAS:528: DyaK28XhtlWrt7Y%3D 8593709
-
(1996)
Circ. Res.
, vol.78
, pp. 499-503
-
-
Spector, P.S.1
Curran, M.E.2
Keating, M.T.3
-
15
-
-
0025261059
-
Depressant effects of chlorquine on the isolated guinea-pig heart
-
10.1016/0014-2999(90)90108-I 1:CAS:528:DyaK3cXktVSiu7c%3D 2340863
-
L. Tona Y. -C. H. NG T. Akera T. M. Brody 1990 Depressant effects of chlorquine on the isolated guinea-pig heart Eur. J. Pharmacol. 178 293 301 10.1016/0014-2999(90)90108-I 1:CAS:528:DyaK3cXktVSiu7c%3D 2340863
-
(1990)
Eur. J. Pharmacol.
, vol.178
, pp. 293-301
-
-
Tona, L.1
Ng, Y.-C.H.2
Akera, T.3
Brody, T.M.4
-
16
-
-
0000841151
-
Cinchona derivatives in the treatment of heart disorders
-
K. F. Wenckebach 1923 Cinchona derivatives in the treatment of heart disorders JAMA 81 472 474
-
(1923)
JAMA
, vol.81
, pp. 472-474
-
-
Wenckebach, K.F.1
-
17
-
-
0033798205
-
Familial and acquired long QT syndrome and the cardiac rapid delayed rectifier potassium current
-
10.1046/j.1440-1681.2000.03337.x 1:CAS:528:DC%2BD3cXntValsLc%3D 11022966
-
H. J. Witchel J. C. Hanconx 2000 Familial and acquired long QT syndrome and the cardiac rapid delayed rectifier potassium current Clin. Exp. Pharmacol. Physiol. 27 753 766 10.1046/j.1440-1681.2000.03337.x 1:CAS:528: DC%2BD3cXntValsLc%3D 11022966
-
(2000)
Clin. Exp. Pharmacol. Physiol.
, vol.27
, pp. 753-766
-
-
Witchel, H.J.1
Hanconx, J.C.2
|