Monitoring antisaccades: Inter-individual differences in cognitive control and the influence of COMT and DRD4 genotype variations

Experimental Brain Research

Volumn 203, Issue 2, 2010, Pages 453-463

  Kattoulas, Emmanouil ^a,c   Evdokimidis, Ioannis ^a   Stefanis, Nicholas C ^b,c   Avramopoulos, Dimitrios ^d   Stefanis, Costas N ^c   Smyrnis, Nikolaos ^a,b  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

^c UNIVERSITY MENTAL HEALTH RESEARCH INSTITUTE   (Greece)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Error detection; Gene; Inhibition; Post error adaptation; Saccade

Indexed keywords

CATECHOL METHYLTRANSFERASE; DOPAMINE 4 RECEPTOR;

ADULT; AMPLITUDE MODULATION; ARTICLE; COGNITION; CONSCIOUSNESS; ERROR; GENE FREQUENCY; GENETIC DIFFERENCE; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SACCADIC EYE MOVEMENT; SENSITIVITY AND SPECIFICITY; TASK PERFORMANCE;

ATTENTION; CATECHOL O-METHYLTRANSFERASE; COGNITION; EXECUTIVE FUNCTION; FIXATION, OCULAR; GENETIC ASSOCIATION STUDIES; GENETIC VARIATION; GENOTYPE; HUMANS; MALE; PHOTIC STIMULATION; REACTION TIME; RECEPTORS, DOPAMINE D4; SACCADES; SIGNAL PROCESSING, COMPUTER-ASSISTED; YOUNG ADULT;

EID: 77954427216     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00221-010-2250-2     Document Type: Article

References (38)

1. Avramopoulos D, Stefanis NC, Hantoumi I, Smyrnis N, Evdokimidis I et al (2002) Higher scores of self reported schizotypy in healthy young males carrying the COMT high activity allele. Mol Psychiatry 7:706-711
2. Blasi G, Mattay VS, Bertolino A, Elvevag B, Callicott JH et al (2005) Effect of catechol-O-methyltransferase val158met genotype on attentional control. J Neurosci 25:5038-5045
3. Botvinick MM, Braver TS, Barch DM, Carter CS, Cohen JD (2001) Conflict monitoring and cognitive control. Psychol Rev 108:624-652
4. Botvinick MM, Cohen JD, Carter CS (2004) Conflict monitoring and anterior cingulate cortex: an update. Trends Cogn Sci 12:539-546
5. Carter CS, Braver TS, Barch DM, Botvinick MM, Noll D et al (1998) Anterior cingulate cortex, error detection and the online monitoring of performance. Science 280:747-749
6. Chen J, Lipska BK, Halim N, Ma QD, Matsumoto M et al (2004) Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzymeactivity in postmortem human brain. Amer J Hum Genet 75:807-821
7. Egan MF, Goldberg TE, Kolachana BS, Callicott JH, Mazzanti CM et al (2001) Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proc Natl Acad Sci USA 98:6917-6922
8. Endrass T, Franke C, Kathmann N (2005) Error awareness in a saccade countermanding task. J Psychophysiol 19:275-280
9. Endrass T, Reuter B, Kathmann N (2007) ERP correlates of conscious error cognition: aware and unaware errors in an antisaccade task. Eur J Neurosci 26:1714-1720
10. Evdokimidis I, Smyrnis N, Constantinidis TS, Stefanis NC, Avramopoulos D et al (2002) The antisaccade task in a sample of 2,006 young men. I. Normal population characteristics. Exp Brain Res 147:45-52
11. Everling S, Fischer B (1998) The antisaccade: a review of basic research and clinical studies. Neuropsychologia 36:885-899
12. Fischer B, Weber H (1992) Characteristics of "anti" saccades in man. Exp Brain Res 89:415-424
13. Fossella J, Sommer T, Fan J, Wu Y, Swanson JM et al (2002) Assessing the molecular genetics of attention networks. BMC Neurosci 3:14
14. Hallett PE (1978) Primary and secondary saccades to goals defined by instruction. Exp Brain Res 18:1279-1296
15. Holroyd CB, Coles MGH (2002) The neural basis of human error processing: reinforcement learning, dopamine and the errorrelated negativity. Psychol Rev 109:679-699
16. Klein TA, Endrass T, Kathmann N, Neumann J, von Cramon DY et al (2007) Neural correlates of error awareness. Neuroimage 34:1774-1781
17. Krämer UM, Cunillera T, Càmara E, Marco-Pallarás J, Cucurell D et al (2007) The impact of catechol-O-methyltransferase and dopamine D4 receptor genotypes on neurophysiological markers of performance monitoring. J Neurosci 27:14190-14198
18. Macmillan NA, Creelman CD (2005) Detection theory: a user's guide, 2nd edn. Lawrence Erlbaum Associates, Mahwah
19. Marco-Pallarás J, Camara E, Münte TF, Rodríguez- Fornells A (2008) Neural mechanisms underlying adaptive actions after slips. J Cogn Neurosci 20:1595-1610
20. Massen C (2004) Parallel programming of exogenous and endogenous components in the antisaccade task. Q J Exp Psychol A 57:475-498
21. Miller EK, Cohen JD (2001) An integrative theory of prefrontal cortex function. Annu Rev Neurosci 24:167-202
22. Mokler A, Fischer B (1999) The recognition and correction of involuntary prosaccades in an antisaccade task. Exp Brain Res 125:511-516
23. Munoz DP, Everling S (2004) Look away: the anti-saccade task and the voluntary control of eye movement. Nature 5:218-228
24. Nieuwenhuis S, Ridderinkhof KR, Blom J, Band GPH, Kok A (2001) Error-related brain potentials are differentially related to awareness of response errors: evidence from an antisaccade task. Psychophysiology 38:752-760
25. Oak JN, Oldenhof J, Van Tol HHM (2000) The dopamine D4 receptor: one decade of research. Eur J Pharmacol 405:303-327
26. Okuyama Y, Ishiguro H, Toru M, Arinami T (1999) A genetic polymorphism in the promoter region of DRD4 associated with expression and schizophrenia. BiochemBiophResCo258:292-295
27. Pierrot-Deseilligny C, Milea D, Muri R (2004) Eye movement control by the cerebral cortex. Curr Opin Neurol 17:17-25
28. Rabbitt PM (1966) Errors and error-correction in choice-response tasks. J Exp Psychol 71:264-272
29. Rabbitt PM (2002) Consciousness is slower than you think. Q J Exp Psychol A 55:1081-1092
30. Riba J, Rodriguez-Fornells A, Monte A, Munte TF, Barbanoj MJ (2005) Noradrenergic stimulation enhances human action monitoring. J Neurosci 25:4370-4374
31. Ridderinkhof KR, Van den Wildenberg WPM, Segalowitz SJ, Carter CS (2004) Neurocognitive mechanisms of cognitive control: the role of prefrontal cortex in action selection, response, inhibition, performance monitoring and reward-based learning. Brain Cogn 56:129-140
32. Rubinstein M, Philips TJ, Bunjow JR, Falzone TL, Driewczapolski G et al (1997) Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine and methamphetamine. Cell 90:991-1001
33. Schall JD, Stuphorn V, Brown JW (2002) Monitoring and control of action by the frontal lobes. Neuron 36:309-322
34. Smyrnis N, Evdokimidis I, Stefanis NC, Constantinidis TS, Avramopoulos D et al (2002) The antisaccade task in a sample of 2, 006 young males. II. Effects of task parameters. Exp Brain Res 147:53-63
35. Smyrnis N, Evdokimidis I, Stefanis NC, Avramopoulos D, Constantinidis TS et al (2003) Antisaccade performance of 1,273 men: effects of schizotypy, anxiety, and depression. J Abnorm Psychol 112:403-414
36. Snedecor GW, Cochran WG (1980) Statistical methods, 7th edn. The Iowa State University Press, Ames
37. Van Veen V, Carter CS (2002) The anterior cingulate as a conflict monitor: fMRI and ERP studies. Physiol Behav 77:477-482
38. Velanova K, Wheeler ME, Luna B (2008) Maturational changes in anterior cingulate and frontoparietal recruitment support the development of error processing and inhibitory control. Cereb Cortex 18:2505-2522