Anti-human HB-EGF monoclonal antibodies inhibiting ectodomain shedding of HB-EGF and diphtheria toxin binding

Journal of Biochemistry

Volumn 148, Issue 1, 2010, Pages 55-69

  Hamaoka, Miki ^a   Chinen, Ichino ^a   Murata, Takuya ^b   Takashima, Seiji ^c   Iwamoto, Ryo ^a   Mekada, Eisuke ^a  

^a OSAKA UNIVERSITY   (Japan)

^b SAISEIKAI NAKATSU HOSPITAL   (Japan)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

ectodomain shedding; EGF receptor; epitope mapping; growth inhibition; HB EGF

Indexed keywords

DIPHTHERIA TOXIN; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; MONOCLONAL ANTIBODY; RECOMBINANT HUMAN HEPARIN BINDING EPIDERMAL GROWTH FACTOR ANTIBODY; UNCLASSIFIED DRUG; HBEGF PROTEIN, HUMAN; HBEGF PROTEIN, MOUSE; MITOGENIC AGENT; PROTEIN BINDING; SIGNAL PEPTIDE;

ANIMAL EXPERIMENT; ANTIBODY AND IMMUNOGLOBULIN PRODUCTION; ANTIGEN BINDING; ARTICLE; CELL GROWTH; COCULTURE; CONTROLLED STUDY; ECTODERM; EPITOPE MAPPING; GROWTH INHIBITION; HYBRIDOMA; MITOGENESIS; MOLECULAR CLONING; MOUSE; NONHUMAN; PROTEIN BINDING; AMINO ACID SEQUENCE; ANIMAL; ANTIBODY SPECIFICITY; BIOSYNTHESIS; CELL LINE; CELL MEMBRANE; CELL PROLIFERATION; CHEMISTRY; HUMAN; IMMUNIZATION; IMMUNOASSAY; IMMUNOLOGY; IMMUNOPRECIPITATION; METABOLISM; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; SERODIAGNOSIS;

MUS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; CELL LINE; CELL MEMBRANE; CELL PROLIFERATION; COCULTURE TECHNIQUES; DIPHTHERIA TOXIN; EPITOPE MAPPING; HEPARIN-BINDING EGF-LIKE GROWTH FACTOR; HUMANS; IMMUNIZATION; IMMUNOASSAY; IMMUNOPRECIPITATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MITOGENS; MOLECULAR SEQUENCE DATA; NEUTRALIZATION TESTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

EID: 77954400623     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvq033     Document Type: Article

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