Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability

Journal of Cell Biology

Volumn 189, Issue 7, 2010, Pages 1097-1105

  Lin, Chiou Hong ^a,b   Hu, Chi Kuo ^c   Shih, Hsiu Ming ^a,b  

^a ACADEMIA SINICA   (Taiwan)

^b INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AURORA A KINASE; CLATHRIN HEAVY CHAIN; TRANSFORMING ACIDIC COILED COIL CONTAINING PROTEIN 3; UNCLASSIFIED DRUG;

ARTICLE; CHROMOSOME; CONTROLLED STUDY; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; MITOSIS; MITOSIS INHIBITION; MITOSIS SPINDLE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION;

CLATHRIN HEAVY CHAINS; HELA CELLS; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MITOSIS; MITOTIC SPINDLE APPARATUS; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES;

EID: 77954393655     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200911120     Document Type: Article

References (30)

1. Barr, A.R., and F. Gergely. 2007. Aurora-A: the maker and breaker of spindle poles. J. Cell Sci. 120:2987-2996. doi:10.1242/jcs.013136
2. Barr, A.R., and F. Gergely. 2008. MCAK-independent functions of ch-Tog/ XMAP215 in microtubule plus-end dynamics. Mol. Cell. Biol. 28:7199-7211. doi:10.1128/MCB.01040-08
3. Brittle, A.L., and H. Ohkura. 2005. Centrosome maturation: Aurora lights the way to the poles. Curr. Biol. 15:R880-R882. doi:10.1016/j.cub.2005.10.022
4. Cassimeris, L., D. Gard, P.T. Tran, and H.P. Erickson. 2001. XMAP215 is a long thin molecule that does not increase microtubule stiffness. J. Cell Sci. 114:3025-3033. (Pubitemid 32821540)
5. Gaglio, T., A. Saredi, and D.A. Compton. 1995. NuMA is required for the organization of microtubules into aster-like mitotic arrays. J. Cell Biol. 131:693-708. doi:10.1083/jcb.131.3.693
6. Gergely, F., V.M. Draviam, and J.W. Raff. 2003. The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells. Genes Dev. 17:336-341. doi:10.1101/gad.245603 (Pubitemid 36182191)
7. Giet, R., R. Uzbekov, F. Cubizolles, K. Le Guellec, and C. Prigent. 1999. The Xenopus laevis aurora-related protein kinase pEg2 associates with and phosphorylates the kinesin-related protein XlEg5. J. Biol. Chem. 274:15005-15013. doi:10.1074/jbc.274.21.15005
8. Giet, R., D. McLean, S. Descamps, M.J. Lee, J.W. Raff, C. Prigent, and D.M. Glover. 2002. Drosophila aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules. J. Cell Biol. 156:437-451. doi:10.1083/jcb.200108135 (Pubitemid 34839893)
9. Hoar, K., A. Chakravarty, C. Rabino, D. Wysong, D. Bowman, N. Roy, and J.A. Ecsedy. 2007. MLN8054, a small-molecule inhibitor of Aurora A, causes spindle pole and chromosome congression defects leading to aneuploidy. Mol. Cell. Biol. 27:4513-4525. doi:10.1128/MCB.02364-06 (Pubitemid 46906573)
10. Kinoshita, K., T.L. Noetzel, L. Pelletier, K. Mechtler, D.N. Drechsel, A. Schwager, M. Lee, J.W. Raff, and A.A. Hyman. 2005. Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis. J. Cell Biol. 170:1047-1055. doi:10.1083/jcb.200503023
11. Kline-Smith, S.L., and C.E. Walczak. 2004. Mitotic spindle assembly and chromosome segregation: refocusing on microtubule dynamics. Mol. Cell. 15:317-327. doi:10.1016/j.molcel.2004.07.012 (Pubitemid 39092749)
12. Lee, M.J., F. Gergely, K. Jeffers, S.Y. Peak-Chew, and J.W. Raff. 2001. Msps/ XMAP215 interacts with the centrosomal protein D-TACC to regulate microtubule behaviour. Nat. Cell Biol. 3:643-649. doi:10.1038/35083033
13. LeRoy, P.J., J.J. Hunter, K.M. Hoar, K.E. Burke, V. Shinde, J. Ruan, D. Bowman, K. Galvin, and J.A. Ecsedy. 2007. Localization of human TACC3 to mitotic spindles is mediated by phosphorylation on Ser558 by Aurora A: a novel pharmacodynamic method for measuring Aurora A activity. Cancer Res. 67:5362-5370. doi:10.1158/0008-5472.CAN-07-0122
14. Lin, D.Y., Y.S. Huang, J.C. Jeng, H.Y. Kuo, C.C. Chang, T.T. Chao, C.C. Ho, Y.C. Chen, T.P. Lin, H.I. Fang, et al. 2006. Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors. Mol. Cell. 24:341-354. doi:10.1016/j.molcel.2006.10.019
15. Marumoto, T., S. Honda, T. Hara, M. Nitta, T. Hirota, E. Kohmura, and H. Saya. 2003. Aurora-A kinase maintains the fidelity of early and late mitotic events in HeLa cells. J. Biol. Chem. 278:51786-51795. doi:10.1074/jbc.M306275200
16. Motley, A., N.A. Bright, M.N. Seaman, and M.S. Robinson. 2003. Clathrinmediated endocytosis in AP-2-depleted cells. J. Cell Biol. 162:909-918. doi:10.1083/jcb.200305145
17. Murray, A.W. 1991. Cell cycle extracts. Methods Cell Biol. 36:581-605. doi:10.1016/S0091-679X(08)60298-8
18. O'Brien, L.L., A.J. Albee, L. Liu, W. Tao, P. Dobrzyn, S.B. Lizarraga, and C. Wiese. 2005. The Xenopus TACC homologue, maskin, functions in mitotic spindle assembly. Mol. Biol. Cell. 16:2836-2847. doi:10.1091/mbc.E04-10-0926
19. Okamoto, C.T., J. McKinney, and Y.Y. Jeng. 2000. Clathrin in mitotic spindles. Am. J. Physiol. Cell Physiol. 279:C369-C374.
20. Pascreau, G., J.G. Delcros, J.Y. Cremet, C. Prigent, and Y. Arlot-Bonnemains. 2005. Phosphorylation of maskin by Aurora-A participates in the control of sequential protein synthesis during Xenopus laevis oocyte maturation. J. Biol. Chem. 280:13415-13423. doi:10.1074/jbc.M410584200
21. Peset, I., and I. Vernos. 2008. The TACC proteins: TACC-ling microtubule dynamics and centrosome function. Trends Cell Biol. 18:379-388. doi:10.1016/j.tcb.2008.06.005
22. Peset, I., J. Seiler, T. Sardon, L.A. Bejarano, S. Rybina, and I. Vernos. 2005. Function and regulation of Maskin, a TACC family protein, in microtubule growth during mitosis. J. Cell Biol. 170:1057-1066. doi:10.1083/jcb.200504037
23. Royle, S.J., and L. Lagnado. 2006. Trimerisation is important for the function of clathrin at the mitotic spindle. J. Cell Sci. 119:4071-4078. doi:10.1242/jcs.03192
24. Royle, S.J., N.A. Bright, and L. Lagnado. 2005. Clathrin is required for the function of the mitotic spindle. Nature. 434:1152-1157. doi:10.1038/ nature03502
25. Sasai, K., J.M. Parant, M.E. Brandt, J. Carter, H.P. Adams, S.A. Stass, A.M. Killary, H. Katayama, and S. Sen. 2008. Targeted disruption of Aurora A causes abnormal mitotic spindle assembly, chromosome misalignment and embryonic lethality. Oncogene. 27:4122-4127. doi:10.1038/onc.2008.47 (Pubitemid 351931992)
26. Schmid, S.L. 1997. Clathrin-coated vesicle formation and protein sorting: an integrated process. Annu. Rev. Biochem. 66:511-548. doi:10.1146/annurev. biochem.66.1.511
27. Schneider, L., F. Essmann, A. Kletke, P. Rio, H. Hanenberg, W. Wetzel, K. Schulze-Osthoff, B. Nürnberg, and R.P. Piekorz. 2007. The transforming acidic coiled coil 3 protein is essential for spindle-dependent chromosome alignment and mitotic survival. J. Biol. Chem. 282:29273-29283. doi:10.1074/jbc.M704151200 (Pubitemid 350043368)
28. Silljé, H.H., S. Nagel, R. Körner, and E.A. Nigg. 2006. HURP is a Ran-importin beta-regulated protein that stabilizes kinetochore microtubules in the vicinity of chromosomes. Curr. Biol. 16:731-742. doi:10.1016/j.cub.2006.02.070
29. Wong, J., R. Lerrigo, C.Y. Jang, and G. Fang. 2008. Aurora A regulates the activity of HURP by controlling the accessibility of its microtubule-binding domain. Mol. Biol. Cell. 19:2083-2091. doi:10.1091/mbc.E07-10-1088
30. Yamauchi, T., T. Ishidao, T. Nomura, T. Shinagawa, Y. Tanaka, S. Yonemura, and S. Ishii. 2008. A B-Myb complex containing clathrin and filamin is required for mitotic spindle function. EMBO J. 27:1852-1862. doi:10.1038/emboj.2008.118