Assessment of azoospermia and histological evaluation of spermatogenesis;Bilan d'une azoospermie et évaluation histologique de la spermatogenèse

Annales de Pathologie

Volumn 30, Issue 3, 2010, Pages 182-195

  Robin, Geoffroy ^a,b   Boitrelle, Florence ^a   Leroy, Xavier ^b   Peers, Marie Claire ^a   Marcelli, François ^a   Rigot, Jean Marc ^a   Mitchell, Valérie ^a  

^a Rouen Normandy University Hospital   (France)

^b LILLE UNIVERSITY HOSPITAL   (France)

Author keywords

Azoospermia; Spermatogenesis; Testicular biopsy

Indexed keywords

FOLLITROPIN; LUTEINIZING HORMONE; PROLACTIN; PROTAMINE; TESTOSTERONE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ASPIRATION BIOPSY; AZOOSPERMIA; CLINICAL EXAMINATION; ECHOGRAPHY; GENE DELETION; GENE EXPRESSION; HISTOLOGY; HORMONE BLOOD LEVEL; HUMAN; HUMAN TISSUE; KARYOTYPING; MALE; MICRODISSECTION; OLIGOSPERMIA; PHENOTYPE; PREVALENCE; SERTOLI CELL ONLY SYNDROME; SHORT SURVEY; SPERMATOGENESIS; SPERMATOZOON; TESTIS BIOPSY; Y CHROMOSOME;

EID: 77954386052     PISSN: 02426498     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.annpat.2010.03.015     Document Type: Short Survey

References (80)

1. Roosen-Runge E.C., Marberger E., Nelson W.O. Quantitative investigations on human testicular biopsies II. Infertility and other conditions. Fertil Steril 1957, 8:203-219.
2. Clermont Y. The cycle of the seminiferous epithelium in man. Am J Anat 1963, 112:35-51.
3. Johnsen S.G. Testicular biopsy score count - a method for registration of spermatogenesis in human testes: normal values and results in 335 hypogonadal males. Hormones 1970, 1:2-25.
4. Levin H.S. Testicular biopsy in the study of male infertility: its current usefulness, histologic techniques, and prospects for the future. Hum Pathol 1979, 10:569-584.
5. Silber S.J., Rodriguez-Rigau L.J. Quantitative analysis of testicle biopsy: determination of partial obstruction and prediction of sperm count after surgery for obstruction. Fertil Steril 1981, 36:480-485.
6. DeKretzer D.M., Holstein A.F. Testicular biopsy and abnormal germ cells; human semen and fertility regulation in men 1976, Hafez ESE, St Louis, p. 332-343.
7. Schoysman R., Vanderzwalmen P., Nijs M., Segal-Bertin G., van de Casseye M. Successful fertilization by testicular spermatozoa in an in-vitro fertilization programme. Hum Reprod 1993, 8:1339-1340.
8. Devroey P., Liu J., Nagy Z., Goossens A., Tournaye H., Camus M., et al. Pregnancies after testicular sperm extraction and intracytoplasmic sperm injection in non-obstructive azoospermia. Hum Reprod 1995, 10:1457-1460.
9. Tournaye H., Camus M., Goossens A., Liu J., Nagy P., Silber S., et al. Recent concepts in the management of infertility because of non-obstructive azoospermia. Hum Reprod 1995, 10(Suppl. 1):115-119.
10. Nicopoullos J.D., Ramsay J.W., Almeida P.A., Gilling-Smith C. Assisted reproduction in the azoospermic couple. BJOG 2004, 111:1190-1203.
11. Oates R.D. The genetic basis of male reproductive failure. Urol Clin North Am 2008, 35:257-270. IX.
12. Ezeh U.I., Taub N.A., Moore H.D., Cooke I.D. Establishment of predictive variables associated with testicular sperm retrieval in men with non-obstructive azoospermia. Hum Reprod 1999, 14:1005-1012.
13. Young J. Hypogonadismes hypogonadotrophiques congénitaux chez l'homme: aspects diagnostiques, physiopathologiques et génétiques. Med Reprod 2007, 9:318-328.
14. Salenave S, Droumaguet C., Néraud B., Chanson P., Young J. Les hypogonadismes hypogonadotropes acquis. Med Reprod 2007, 9:329-336.
15. Huyghe E., Izard V., Rigot J.M., Pariente J.L., Tostain J. Optimal evaluation of the infertile male 2007. French urological association guidelines. Prog Urol 2008, 18:95-101.
16. Rigot J.M. Le bilan clinique est déjà un facteur pronostique. J Gynecol Obstet Biol Reprod 2007, 36:S74-77.
17. Robin G., Marcelli F., Mitchell V., Marchetti C., Lemaître L., Dewailly D., et al. Why and how to assess hypospermia?. Gynecol Obstet Fertil 2008, 36:1035-1042.
18. Soufir J.C. Azoospermia, asthenozoospermia and seminal biochemistry. Ann Biol Clin (Paris) 1985, 43:67-70.
19. Bhasin S. Approach to the infertile man. J Clin Endocrinol Metab 2007, 92:1995-2004.
20. Taskinen S., Lehtinen A., Hovatta O., Wikstrom S. Ultrasonography and colour doppler flow in the testes of adult patients after treatment of cryptorchidism. Br J Urol 1996, 78:248-251.
21. Schiff J.D., Li P.S., Goldstein M. Correlation of ultrasonographic and orchidometer measurements of testis volume in adults. BJU Int 2004, 93:1015-1017.
22. Mancini M., Carmignani L., Gazzano G., Sagone P., Gadda F., Bosari S., et al. High prevalence of testicular cancer in azoospermic men without spermatogenesis. Hum Reprod 2007, 22:1042-1046.
23. Parsons R.B., Fisher A.M., Bar-Chama N., Mitty H.A. MR imaging in male infertility. Radiographics 1997, 17:627-637.
24. Marcelli F., Robin G., Mitchell V., Dumur V., Puech P., Lemaitre L., et al. Role of deep seminal tract imaging in the diagnosis of unilateral agenesis of the vas deferens. Case report of a patient with CFTR gene mutation. Prog Urol 2006, 16:617-619.
25. Simoni M., Bakker E., Krausz C. EAA/EMQN best practice guidelines for molecular diagnosis of Y-chromosomal microdeletions. State of the art 2004. Int J Androl 2004, 27:240-249.
26. Chantot-Bastaraud S., Ravel C., Mc Elreavey K., Siffroi J.P. Microdélétions du bras long du chromosome Y: relations génotype-phénotype. Med Reprod 2007, 9:303-310.
27. Foresta C, Moro E., Ferlin A.Y. Chromosome microdeletions and alterations of spermatogenesis. Endocr Rev 2001, 22:226-239.
28. de la Taille A., Rigot J.M., Mahe P., Vankemmel O., Gervais R., Dumur V., et al. Correlation between genito-urinary anomalies, semen analysis and CFTR genotype in patients with congenital bilateral absence of the vas deferens. Br J Urol 1998, 81:614-619.
29. de la Taille A., Houlgatte A., Houdelette P., Berlizot P., Lanfrey P., Atger M., et al. Role of testicular biopsy in the investigation of a carcinoma in situ. Prog Urol 1997, 7:209-214.
30. Horwich A. Current issues in the management of clinical stage I testicular teratoma. Eur J Cancer 1993, 29A:933-934.
31. Osterlind A., Berthelsen J.G., Abildgaard N., Hansen S.O., Hjalgrim H., Johansen B., et al. Risk of bilateral testicular germ cell cancer in denmark: 1960-1984. J Natl Cancer Inst 1991, 83:1391-1395.
32. Lin W.W. Diagnosis and treatment of the azoospermic patient. Curr Urol Rep 2001, 2:448-452.
33. Jow W.W., Steckel J., Schlegel P.N., Magid M.S., Goldstein M. Motile sperm in human testis biopsy specimens. J Androl 1993, 14:194-198.
34. Tournaye H., Verheyen G., Nagy P., Ubaldi F., Goossens A., Silber S., et al. Are there any predictive factors for successful testicular sperm recovery in azoospermic patients?. Hum Reprod 1997, 12:80-86.
35. Ezeh U.I., Moore H.D., Cooke I.D. A prospective study of multiple needle biopsies versus a single open biopsy for testicular sperm extraction in men with non-obstructive azoospermia. Hum Reprod 1998, 13:3075-3080.
36. Amer M., Haggar S.E., Moustafa T., Abd El-Naser T., Zohdy W. Testicular sperm extraction: impact of testicular histology on outcome, number of biopsies to be performed and optimal time for repetition. Hum Reprod 1999, 14:3030-3034.
37. Su L.M., Palermo G.D., Goldstein M., Veeck L.L., Rosenwaks Z., Schlegel P.N. Testicular sperm extraction with intracytoplasmic sperm injection for nonobstructive azoospermia: testicular histology can predict success of sperm retrieval. J Urol 1999, 161:112-116.
38. Mitchell V., Lefebvre-Khalil V., Thomas P., Rigot J.M., Steger K. Transition protein 1 mRNA expression is not related to pregnancy rate in azoospermic men undergoing TESE-ICSI. Andrologia 2007, 39:124-127.
39. Mitchell V., Steger K., Marchetti C., Herbaut J.C., Devos P., Rigot J.M. Cellular expression of protamine 1 and 2 transcripts in testicular spermatids from azoospermic men submitted to TESE-ICSI. Mol Hum Reprod 2005, 11:373-379.
40. Steger K. Perspectives in the diagnosis of testicular biopsies using molecular biological techniques. Andrologia 2003, 35:183.
41. Steger K. Possible predictive factors for ICSI? Molecular biology techniques in combination with therapeutic testicular biopsies. Andrologia 2003, 35:200-208.
42. Steger K., Wilhelm J., Konrad L., Stalf T., Greb R., Diemer T., et al. Both protamine-1 to protamine-2 mRNA ratio and BCL2 mRNA content in testicular spermatids and ejaculated spermatozoa discriminate between fertile and infertile men. Hum Reprod 2008, 23:11-16.
43. Schlegel P.N., Su L.M. Physiological consequences of testicular sperm extraction. Hum Reprod 1997, 12:1688-1692.
44. Herwig R., Tosun K., Schuster A., Rehder P., Glodny B., Wildt L., et al. Tissue perfusion-controlled guided biopsies are essential for the outcome of testicular sperm extraction. Fertil Steril 2007, 87:1071-1076.
45. Friedler S., Raziel A., Strassburger D., Soffer Y., Komarovsky D., Ron-El R. Testicular sperm retrieval by percutaneous fine needle sperm aspiration compared with testicular sperm extraction by open biopsy in men with non-obstructive azoospermia. Hum Reprod 1997, 12:1488-1493.
46. Rosenlund B., Kvist U., Ploen L., Rozell B.L., Sjoblom P., Hillensjo T. A comparison between open and percutaneous needle biopsies in men with azoospermia. Hum Reprod 1998, 13:1266-1271.
47. Tournaye H. Surgical sperm recovery for intracytoplasmic sperm injection: Which method is to be preferred?. Hum Reprod 1999, 14(Suppl. 1):71-81.
48. Schlegel P.N. Testicular sperm extraction: Microdissection improves sperm yield with minimal tissue excision. Hum Reprod 1999, 14:131-135.
49. Amer M., Zohdy W., Abd El Naser T., Hosny H., Arafa M., Fakhry E. Single tubule biopsy: A new objective microsurgical advancement for testicular sperm retrieval in patients with nonobstructive azoospermia. Fertil Steril 2008, 89:592-596.
50. Schiff J.D., Palermo G.D., Veeck L.L., Goldstein M., Rosenwaks Z., Schlegel P.N. Success of testicular sperm extraction [corrected] and intracytoplasmic sperm injection in men with klinefelter syndrome. J Clin Endocrinol Metab 2005, 90:6263-6267.
51. Schoor R.A., Elhanbly S., Niederberger C.S., Ross L.S. The role of testicular biopsy in the modern management of male infertility. J Urol 2002, 167:197-200.
52. Raman J.D., Schlegel P.N. Testicular sperm extraction with intracytoplasmic sperm injection is successful for the treatment of nonobstructive azoospermia associated with cryptorchidism. J Urol 2003, 170:1287-1290.
53. Donoso P., Tournaye H., Devroey P. Which is the best sperm retrieval technique for non-obstructive azoospermia? A systematic review. Hum Reprod Update 2007, 13:539-549.
54. Wald M., Makhlouf A.A., Niederberger C.S. Therapeutic testis biopsy for sperm retrieval. Curr Opin Urol 2007, 17:431-438.
55. Harris S.E., Sandlow J.I. Sperm acquisition in nonobstructive azoospermia: What are the options?. Urol Clin North Am 2008, 35:235-242. IX.
56. Turek P.J., Givens C.R., Schriock E.D., Meng M.V., Pedersen R.A., Conaghan J. Testis sperm extraction and intracytoplasmic sperm injection guided by prior fine-needle aspiration mapping in patients with nonobstructive azoospermia. Fertil Steril 1999, 71:552-557.
57. Van Peperstraten A., Proctor M.L., Johnson N.P., Philipson G. Techniques for surgical retrieval of sperm prior to ICSI for azoospermia. Cochrane Database Syst Rev 2006, 3:CD002807.
58. Van Peperstraten A., Proctor M.L., Johnson N.P., Philipson G. Techniques for surgical retrieval of sperm prior to intra-cytoplasmic sperm injection (ICSI) for azoospermia. Cochrane Database Syst Rev 2008, CD002807.
59. Grizard G., Force A., Janny L., Boucher D. Principes de préparation et de congélation des spermatozoïdes testiculaires humains. Andrologie 2003, 13:128-133.
60. Lornage J., Giscard D'Estain S., Lejeune H., Benchaïd M., Cottinet D., Salle B., et al. Les prélèvements testiculaires dans les azoospermies sécrétoires: le point de vue du biologiste de la reproduction sur la lecture du prélèvement. Andrologie 2001, 11:127-132.
61. Tsujimura A., Matsumiya K., Miyagawa Y., Tohda A., Miura H., Nishimura K., et al. Conventional multiple or microdissection testicular sperm extraction: a comparative study. Hum Reprod 2002, 17:2924-2929.
62. Silber S.J., Nagy Z., Devroey P., Tournaye H., Van Steirteghem A.C. Distribution of spermatogenesis in the testicles of azoospermic men: the presence or absence of spermatids in the testes of men with germinal failure. Hum Reprod 1997, 12:2422-2428.
63. McLachlan R.I., Rajpert-De Meyts E., Hoei-Hansen C.E., de Kretser D.M., Skakkebaek N.E. Histological evaluation of the human testis-approaches to optimizing the clinical value of the assessment: mini review. Hum Reprod 2007, 22:2-16.
64. Tournaye H., Camus M., Vandervorst M., Nagy Z., Joris H., Van Steirteghem A., et al. Surgical sperm retrieval for intracytoplasmic sperm injection. Int J Androl 1997, 20(Suppl. 3):69-73.
65. Anniballo R., Ubaldi F., Cobellis L., Sorrentino M., Rienzi L., Greco E., Tesarik J. Criteria predicting the absence of spermatozoa in the sertoli cell-only syndrome can be used to improve success rates of sperm retrieval. Hum Reprod 2000, 15:2269-2277.
66. Jezek D., Knuth U.A., Schulze W. Successful testicular sperm extraction (TESE) in spite of high serum follicle stimulating hormone and azoospermia: correlation between testicular morphology, TESE results, semen analysis and serum hormone values in 103 infertile men. Hum Reprod 1998, 13:1230-1234.
67. Schulze W., Thoms F., Knuth U.A. Testicular sperm extraction: Comprehensive analysis with simultaneously performed histology in 1418 biopsies from 766 subfertile men. Hum Reprod 1999, 14(Suppl. 1):82-96.
68. Seo J.T., Ko W.J. Predictive factors of successful testicular sperm recovery in non-obstructive azoospermia patients. Int J Androl 2001, 24:306-310.
69. Hung A.J., King P., Schlegel P.N. Uniform testicular maturation arrest: A unique subset of men with nonobstructive azoospermia. J Urol 2007, 178:608-612. [discussion 612].
70. Ishikawa T., Fujioka H., Fujisawa M. Clinical and hormonal findings in testicular maturation arrest. BJU Int 2004, 94:1314-1316.
71. Osmanagaoglu K., Vernaeve V., Kolibianakis E., Tournaye H., Camus M., Van Steirteghem A., et al. Cumulative delivery rates after ICSI treatment cycles with freshly retrieved testicular sperm: a 7-year follow-up study. Hum Reprod 2003, 18:1836-1840.
72. Silber S.J. Microsurgical TESE and the distribution of spermatogenesis in non-obstructive azoospermia. Hum Reprod 2000, 15:2278-2284.
73. Joensen U.N., Jorgensen N., Rajpert-De Meyts E., Skakkebaek N.E. Testicular dysgenesis syndrome and Leydig cell function. Basic Clin Pharmacol Toxicol 2008, 102:155-161.
74. Metzler-Guillemain C., Guichaoua M.R. A simple and reliable method for meiotic studies on testicular samples used for intracytoplasmic sperm injection. Fertil Steril 2000, 74:916-919.
75. Sun F., Turek P., Greene C., Ko E., Rademaker A., Martin R.H. Abnormal progression through meiosis in men with nonobstructive azoospermia. Fertil Steril 2007, 87:565-571.
76. Ghalamoun-Slaimi R., Guichaoua M.R. Histologie testiculaire et méïose dans les stérilités de type non obstructif. Andrologie 2006, 16:135-142.
77. Ma S., Arsovska S., Moens P., Nigro M., Chow V. Analysis of early meiotic events and aneuploidy in nonobstructive azoospermic men: a preliminary report. Fertil Steril 2006, 85:646-652.
78. Carrell D.T., Emery B.R., Peterson C.M. The correlation of sperm chromatin decondensation following in vitro exposure to heparin and sperm penetration rates. J Assist Reprod Genet 1998, 15:560-564.
79. Hammadeh M.E., al-Hasani S., Doerr S., Stieber M., Rosenbaum P., Schmidt W., et al. Comparison between chromatin condensation and morphology from testis biopsy extracted and ejaculated spermatozoa and their relationship to ICSI outcome. Hum Reprod 1999, 14:363-367.
80. Cooperberg M.R., Chi T., Jad A., Cha I., Turek P.J. Variability in testis biopsy interpretation: implications for male infertility care in the era of intracytoplasmic sperm injection. Fertil Steril 2005, 84:672-677.