Transition protein 1 mRNA expression is not related to pregnancy rate in azoospermic men undergoing TESE-ICSI

Andrologia

Volumn 39, Issue 4, 2007, Pages 124-127

  Mitchell, V ^a   Lefebvre Khalil, V ^a   Thomas, P ^a   Rigot, J M ^a   Steger, K ^b  

^a LILLE UNIVERSITY HOSPITAL   (France)

^b UNIVERSITY HOSPITAL GIESSEN   (Germany)

Author keywords

Azoospermia; in situ hybridisation; TESE ICSI; Transition nuclear protein 1

Indexed keywords

MESSENGER RNA; NUCLEAR PROTEIN; TRANSITION NUCLEAR PROTEIN 1; UNCLASSIFIED DRUG;

ADULT; ARTICLE; AZOOSPERMIA; CLINICAL ARTICLE; CONTROLLED STUDY; EMBRYO DEVELOPMENT; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; INTRACYTOPLASMIC SPERM INJECTION; MALE; PREDICTION; PREGNANCY RATE; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; SPERMATID; SPERMATOGENESIS; SPERMATOGONIUM; TESTICULAR SPERM EXTRACTION; TESTIS BIOPSY;

EID: 34547840241     PISSN: 03034569     EISSN: 14390272     Source Type: Journal    
DOI: 10.1111/j.1439-0272.2007.00775.x     Document Type: Article

References (14)

1. Aoki VW, Carrell DT (2003) Human protamines and the developing spermatid: their structure, function, expression and relationship with male infertility. Asian J Androl 5:315 324.
2. Engel W, Keime S, Kremling H, Hameister H, Schluter G (1992) The genes for protamine 1 and 2 (PRM1 and PRM2) and transition protein 2 (TNP2) are closely linked in the mammalian genome. Cytogenet Cell Genet 61:158 159.
3. Heidaran MA, Kozak CA, Kistler WS (1989) Nucleotide sequence of the Stp-1 gene coding for rat spermatid nuclear transition protein 1 (TP1): homology with protamine P1 and assignment of the mouse Stp-1 gene to chromosome 1. Gene 75:39 46.
4. Holstein AF, Schulze W, Davidoff M (2003) Understanding spermatogenesis is a prerequisite for treatment. Reprod Biol Endocrinol 1:107 123.
5. Meistrich ML, Mohapatra B, Shirley CR, Zhao M (2003) Roles of transition nuclear proteins in spermiogenesis. Chromosoma 111:483 488.
6. Mitchell V, Steger K, Marchetti C, Herbaut JC, Devos P, Rigot JM (2005) Cellular expression of protamine 1 and 2 transcripts in testicular spermatids from azoospermic men submitted to TESE-ICSI. Mol Hum Reprod 1:373 379.
7. Miyagawa Y, Nishimura H, Tsujimura A, Matsuoka Y, Matsumiya K, Okuyama A, Nishimune Y, Tanaka H. (2005) Single-nucleotide polymorphisms and mutation analyses of the TNP1 and TNP2 genes of fertile and infertile human male populations. J Androl 26:779 786.
8. Pigny P, Desailloud R, Cortet-Rudelli C, Duhamel A, Deroubaix-Allard D, Racadot A., Dewailly D (1997) Serum alpha-inhibin levels in polycystic ovary syndrome: relationship to the serum androstenedione level. J Clin Endocrinol Metab 8:1939 1943.
9. Shirley CR, Hayashi S, Mounsey S, Yanagimachi R, Meistrich ML (2004) Abnormalities and reduced reproductive potential of sperm from Tnp1- and Tnp2-null double mutant mice. Biol Reprod 71:1220 1229.
10. Steger K (2003) Perspectives in the diagnosis of testicular biopsies using molecular biological techniques. Andrologia 35:200 208.
11. Steger K, Klonisch T, Gavenis K, Behr R, Schaller V, Drabent B, Doenecke D, Nieschlag E, Bergmann M, Weinbauer GF (1999) Round spermatids show normal testis-specific H1t but reduced cAMP-responsive element modulator and transition protein 1 expression in men with round-spermatid maturation arrest. J Androl 20:747 754.
12. Steger K, Fink L, Failing K, Bohle RM, Kliesch S, Weidner W, Bergmann M (2003) Decreased protamine-1 transcripts levels in testes from infertile men. Mol Hum Reprod 9:331 336.
13. Suganuma R, Yanagimachi R, Meistrich ML (2005) Decline in fertility of mouse sperm with abnormal chromatin during epididymal passage as revealed by ICSI. Hum Reprod 20:3101 3108.
14. Yu Y, Zhang Y, Unni E, Shirley C, Deng J, Russel L, Weil M, Behringer R, Meistrich M (2000) Abnormal spermatogenesis and reduced fertility in transition nuclear protein 1-deficient mice. Proc Natl Acad sci USA 97:4683 4688.