Transcription of SST2 somatostatin receptor gene in human pancreatic cancer cells is altered by single nucleotide promoter polymorphism

Gastroenterology

Volumn 120, Issue 1, 2001, Pages 200-209

  Torrisani, Jérôme ^a   Bouisson, Michèle ^a   Puente, Elena ^a   Capellà, Gabriel ^b   Laurent Puig, Pierre ^c   Berger, Anne ^d   Vaysse, Nicole ^a   Susini, Christiane ^a   Buscail, Louis ^a  

^a CHU RANGUEIL   (France)

^b CATALAN INSTITUTE OF ONCOLOGY   (Spain)

^c INSERM   (France)

^d Hopital Laennec   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CYTOSINE; GUANINE; ISOPROTEIN; NUCLEAR FACTOR I; RECEPTOR SUBTYPE; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN RECEPTOR;

ARTICLE; BINDING SITE; CANCER CELL; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; CROSS LINKING; ELECTROPHORETIC MOBILITY; GENE MUTATION; GENE REPRESSION; GENE SEQUENCE; GENE STRUCTURE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PANCREAS CANCER; PRIORITY JOURNAL; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTION INITIATION;

EID: 0035161448     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/gast.2001.21192     Document Type: Article

References (25)

1. The role of somatostatin and its analogs in the diagnosis and treatment of tumors
2. Mechanisms of antineoplastic action of somatostatin analogs
3. Classification and nomenclature of somatostatin receptors
4. Inhibition of cell proliferation of RC-160 is mediated by SSTR2 and SSTR5 human somatostatin receptor subtypes through different mechanisms
5. The tyrosine phosphatase SHP-1 associates with sst2 somatostatin receptor and is an essential component of SST2-mediated inhibitory growth signaling
6. Loss of sst2 somatostatin receptor gene expression in human pancreatic and colorectal cancer
7. Immunohistochemical localization of somatostatin receptors sst2A in human tumors
8. SST2 Somatostatin receptor expression reverses the tumorigenicity of human pancreatic cancer cells
9. Gene therapy for pancreatic carcinoma: Local and distant antitumor effect after somatostatin receptor SST2 gene transfer
10. Cloning of the gene encoding human somatostatin receptor 2: Sequence analysis of the 5′-flanking promoter region
11. Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development
12. Nuclear factor I (NFI) isoforms differentially activate simple versus complex NFI-responsive promoters
13. Nuclear factor I family members regulate the transcription of surfactant protein-C
14. The helix-loop-helix transcription factor SEF-2 regulates the activity of a novel initiator element in the promoter of the human somatostatin receptor II gene
15. Characterization of the promoter region of the human somatostatin receptor subtype 2 gene and localization of sequences required for estrogen-responsiveness
16. Molecular analysis of the somatostatin receptor subtype 2 in human glioma cells
17. Myeloperoxidase genetic polymorphism and lung cancer risk
18. Polymorphism in the tumor necrosis factor-alpha promotor region and in the heat shock protein 70 genes associated with malignant tumors
19. A point mutation in the putative TATA box, detected in nondiseased individuals and patients with hereditary breast cancer, decreases promoter activity of the 17 beta-hydroxysteroid dehydrogenase type 1 gene 2 (EDH17B2) in vitro
20. Mechanism of DNA replication in eukaryotic cells: Cellular host factors stimulating adenovirus DNA replication
21. A member of the CTF/NF-1 transcription factor family regulates murine growth hormone receptor gene promoter activity
22. NF1-L is the DNA-binding component of the protein complex at the peripherin negative regulatory element
23. Analysis of multiple forms of nuclear factor I in human and murine cells
24. The transcription factor nuclear factor I mediates repression of the GLUT4 promoter by insulin
25. Roles of the NFI/CTF gene family in transcription and development