Phosphopeptide screen uncovers novel phosphorylation sites of Nedd4-2 that potentiate its inhibition of the epithelial Na+ channel

Journal of Biological Chemistry

Volumn 285, Issue 28, 2010, Pages 21671-21678

  Hallows, Kenneth R ^a   Bhalla, Vivek ^b   Oyster, Nicholas M ^a   Wijngaarden, Marjolein A ^c   Lee, Jeffrey K ^a   Li, Hui ^a   Chandran, Sindhu ^b   Xia, Xiaoyu ^b   Huang, Zhirong ^d   Chalkley, Robert J ^e   Burlingame, Alma L ^e   Pearce, David ^d  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APICAL MEMBRANES; CATALYTIC DOMAINS; HORMONAL CONTROL; IN-VITRO; INHIBITORY ACTIVITY; ION TRANSPORTS; P38 MAPK; PHOSPHOPEPTIDES; PHOSPHORYLATION SITES; PROTEIN KINASE A; TANDEM MASS SPECTROMETRY; TARGET SEQUENCES; TARGET SITES; UBIQUITIN LIGASES; XENOPUS;

LAWS AND LEGISLATION; MASS SPECTROMETRY; PROTEINS; TARGETS;

PHOSPHORYLATION;

CYCLIC AMP DEPENDENT PROTEIN KINASE; EPITHELIAL SODIUM CHANNEL; LIGASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOPEPTIDE; SERINE; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; STRESS ACTIVATED PROTEIN KINASE 1; THREONINE; UBIQUITIN PROTEIN LIGASE NEDD4 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONSENSUS SEQUENCE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; GENE MUTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; ION TRANSPORT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CATALYTIC DOMAIN; ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT; EPITHELIAL SODIUM CHANNEL; HUMANS; IMMEDIATE-EARLY PROTEINS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 8; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; TANDEM MASS SPECTROMETRY; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; XENOPUS;

EID: 77954351077     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.084731     Document Type: Article

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