-
1
-
-
20144389763
-
Cholesterol binding, efflux, and a PDZ-interacting domain of scavenger receptor-BI mediate HDL-initiated signaling
-
Assanasen C, Mineo C, Seetharam D, Yuhanna IS, Marcel YL, Connelly MA et al. (2005). Cholesterol binding, efflux, and a PDZ-interacting domain of scavenger receptor-BI mediate HDL-initiated signaling. J Clin Invest 115:969 977.
-
(2005)
J Clin Invest
, vol.115
, pp. 969-977
-
-
Assanasen, C.1
Mineo, C.2
Seetharam, D.3
Yuhanna, I.S.4
Marcel, Y.L.5
Connelly, M.A.6
-
2
-
-
0035074174
-
Lessons learned from statin trials
-
Auer J, Berent R, Eber B (2001). Lessons learned from statin trials. Clin Cardiol 24:277 280.
-
(2001)
Clin Cardiol
, vol.24
, pp. 277-280
-
-
Auer, J.1
Berent, R.2
Eber, B.3
-
3
-
-
33644971702
-
Differences in eNOS activity because of subcellular localization are dictated by phosphorylation state rather than the local calcium environment
-
Church JE, Fulton D (2006). Differences in eNOS activity because of subcellular localization are dictated by phosphorylation state rather than the local calcium environment. J Biol Chem 281:1477 1488.
-
(2006)
J Biol Chem
, vol.281
, pp. 1477-1488
-
-
Church, J.E.1
Fulton, D.2
-
4
-
-
0034942037
-
Simvastatin reduces reperfusion injury by modulating nitric oxide synthase expression: An ex vivo study in isolated working rat hearts
-
Di Napoli P, Antonio Taccardi A, Grilli A, Spina R, Felaco M, Barsotti A et al. (2001). Simvastatin reduces reperfusion injury by modulating nitric oxide synthase expression: an ex vivo study in isolated working rat hearts. Cardiovasc Res 51:283 293.
-
(2001)
Cardiovasc Res
, vol.51
, pp. 283-293
-
-
Di Napoli, P.1
Antonio Taccardi, A.2
Grilli, A.3
Spina, R.4
Felaco, M.5
Barsotti, A.6
-
5
-
-
67651033611
-
Efficacy of atorvastatin reload in patients on chronic statin therapy undergoing percutaneous coronary intervention: Results of the ARMYDA-RECAPTURE (Atorvastatin for Reduction of Myocardial Damage during Angioplasty) Randomized Trial
-
Di Sciascio G, Patti G, Pasceri V, Gaspardone A, Colonna G, Montinaro A (2009). Efficacy of atorvastatin reload in patients on chronic statin therapy undergoing percutaneous coronary intervention: results of the ARMYDA-RECAPTURE (Atorvastatin for Reduction of Myocardial Damage During Angioplasty) Randomized Trial. J Am Coll Cardiol 54:558 565.
-
(2009)
J Am Coll Cardiol
, vol.54
, pp. 558-565
-
-
Di Sciascio, G.1
Patti, G.2
Pasceri, V.3
Gaspardone, A.4
Colonna, G.5
Montinaro, A.6
-
6
-
-
0033614802
-
Cholesterol reduction rapidly improves endothelial function after acute coronary syndromes. The RECIFE (reduction of cholesterol in ischemia and function of the endothelium) trial
-
Dupuis J, Tardif JC, Cernacek P, Theroux P (1999). Cholesterol reduction rapidly improves endothelial function after acute coronary syndromes. The RECIFE (reduction of cholesterol in ischemia and function of the endothelium) trial. Circulation 99:3227 3233.
-
(1999)
Circulation
, vol.99
, pp. 3227-3233
-
-
Dupuis, J.1
Tardif, J.C.2
Cernacek, P.3
Theroux, P.4
-
7
-
-
0033730574
-
Do pleiotropic effects of statins beyond lipid alterations exist in vivo? What are they and how do they differ between statins?
-
Faggiotto A, Paoletti R (2000). Do pleiotropic effects of statins beyond lipid alterations exist in vivo? What are they and how do they differ between statins? Curr Atheroscler Rep 2:20 25.
-
(2000)
Curr Atheroscler Rep
, vol.2
, pp. 20-25
-
-
Faggiotto, A.1
Paoletti, R.2
-
8
-
-
0034188762
-
Pleiotropic effects of statins
-
Farmer JA (2000). Pleiotropic effects of statins. Curr Atheroscler Rep 2:208 217.
-
(2000)
Curr Atheroscler Rep
, vol.2
, pp. 208-217
-
-
Farmer, J.A.1
-
9
-
-
0002353629
-
Statin therapy after acute myocardial infarction: Are we adequately treating high-risk patients?
-
Fonarow GC (2002). Statin therapy after acute myocardial infarction: are we adequately treating high-risk patients? Curr Atheroscler Rep 4:99 106.
-
(2002)
Curr Atheroscler Rep
, vol.4
, pp. 99-106
-
-
Fonarow, G.C.1
-
10
-
-
0033542414
-
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
-
Fulton D, Gratton JP, McCabe TJ, Fontana J, Fujio Y, Walsh K et al. (1999). Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature 399:597 601.
-
(1999)
Nature
, vol.399
, pp. 597-601
-
-
Fulton, D.1
Gratton, J.P.2
McCabe, T.J.3
Fontana, J.4
Fujio, Y.5
Walsh, K.6
-
11
-
-
0027987849
-
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
-
Group SSSS (1994). Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 344:1383 1389.
-
(1994)
Lancet
, vol.344
, pp. 1383-1389
-
-
Ssss, G.1
-
12
-
-
3242733932
-
Acute activation and phosphorylation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors
-
Harris MB, Blackstone MA, Sood SG, Li C, Goolsby JM, Venema VJ et al. (2004). Acute activation and phosphorylation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors. Am J Physiol Heart Circ Physiol 287:H560 H566.
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.287
-
-
Harris, M.B.1
Blackstone, M.A.2
Sood, S.G.3
Li, C.4
Goolsby, J.M.5
Venema, V.J.6
-
13
-
-
2142717337
-
In vivo activity of a phospholipase C inhibitor, 1-(6-((17beta-3- methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione (U73122), in acute and chronic inflammatory reactions
-
Hou C, Kirchner T, Singer M, Matheis M, Argentieri D, Cavender D (2004). In vivo activity of a phospholipase C inhibitor, 1-(6-((17beta-3-methoxyestra-1, 3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione (U73122), in acute and chronic inflammatory reactions. J Pharmacol Exp Ther 309:697 704.
-
(2004)
J Pharmacol Exp Ther
, vol.309
, pp. 697-704
-
-
Hou, C.1
Kirchner, T.2
Singer, M.3
Matheis, M.4
Argentieri, D.5
Cavender, D.6
-
14
-
-
0034647595
-
Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect: Reduction of MRNA levels for interleukin-1beta, interleukin-6, cyclooxygenase-2, and p22phox by regulation of peroxisome proliferator-activated receptor alpha (PPARalpha) in primary endothelial cells
-
Inoue I, Goto S, Mizotani K, Awata T, Mastunaga T, Kawai S et al. (2000). Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect: reduction of MRNA levels for interleukin-1beta, interleukin-6, cyclooxygenase-2, and p22phox by regulation of peroxisome proliferator-activated receptor alpha (PPARalpha) in primary endothelial cells. Life Sci 67:863 876.
-
(2000)
Life Sci
, vol.67
, pp. 863-876
-
-
Inoue, I.1
Goto, S.2
Mizotani, K.3
Awata, T.4
Mastunaga, T.5
Kawai, S.6
-
15
-
-
0032896636
-
Pravastatin sodium activates endothelial nitric oxide synthase independent of its cholesterol-lowering actions
-
Kaesemeyer WH, Caldwell RB, Huang J, Caldwell RW (1999). Pravastatin sodium activates endothelial nitric oxide synthase independent of its cholesterol-lowering actions. J Am Coll Cardiol 33:234 241.
-
(1999)
J Am Coll Cardiol
, vol.33
, pp. 234-241
-
-
Kaesemeyer, W.H.1
Caldwell, R.B.2
Huang, J.3
Caldwell, R.W.4
-
16
-
-
0035661773
-
Regulation of cardiac and smooth muscle Ca(2+) channels (Ca(V)1.2a,b) by protein kinases
-
Keef KD, Hume JR, Zhong J (2001). Regulation of cardiac and smooth muscle Ca(2+) channels (Ca(V)1.2a,b) by protein kinases. Am J Physiol Cell Physiol 281:C1743 C1756.
-
(2001)
Am J Physiol Cell Physiol
, vol.281
-
-
Keef, K.D.1
Hume, J.R.2
Zhong, J.3
-
17
-
-
70350719504
-
Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation
-
Kielczewski JL, Jarajapu YP, McFarland EL, Cai J, Afzal A, Calzi SL et al. (2009). Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation. Circ Res 105:897 905.
-
(2009)
Circ Res
, vol.105
, pp. 897-905
-
-
Kielczewski, J.L.1
Jarajapu, Y.P.2
McFarland, E.L.3
Cai, J.4
Afzal, A.5
Calzi, S.L.6
-
18
-
-
33846029854
-
Blockade of scavenger receptor class B type i raises high density lipoprotein cholesterol levels but exacerbates atherosclerotic lesion formation in apolipoprotein e deficient mice
-
Kitayama K, Nishizawa T, Abe K, Wakabayashi K, Oda T, Inaba T et al. (2006). Blockade of scavenger receptor class B type I raises high density lipoprotein cholesterol levels but exacerbates atherosclerotic lesion formation in apolipoprotein E deficient mice. J Pharm Pharmacol 58:1629 1638.
-
(2006)
J Pharm Pharmacol
, vol.58
, pp. 1629-1638
-
-
Kitayama, K.1
Nishizawa, T.2
Abe, K.3
Wakabayashi, K.4
Oda, T.5
Inaba, T.6
-
19
-
-
0001539238
-
Effects of statins on vascular wall: Vasomotor function, inflammation, and plaque stability
-
Koh KK (2000). Effects of statins on vascular wall: vasomotor function, inflammation, and plaque stability. Cardiovasc Res 47:648 657.
-
(2000)
Cardiovasc Res
, vol.47
, pp. 648-657
-
-
Koh, K.K.1
-
20
-
-
0034829678
-
Scavenger receptor class B type i is a multiligand HDL receptor that influences diverse physiologic systems
-
Krieger M (2001). Scavenger receptor class B type I is a multiligand HDL receptor that influences diverse physiologic systems. J Clin Invest 108:793 797.
-
(2001)
J Clin Invest
, vol.108
, pp. 793-797
-
-
Krieger, M.1
-
21
-
-
0033826581
-
The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals
-
Kureishi Y, Luo Z, Shiojima I, Bialik A, Fulton D, Lefer DJ et al. (2000). The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. Nat Med 6:1004 1010.
-
(2000)
Nat Med
, vol.6
, pp. 1004-1010
-
-
Kureishi, Y.1
Luo, Z.2
Shiojima, I.3
Bialik, A.4
Fulton, D.5
Lefer, D.J.6
-
22
-
-
33748454280
-
Direct nitric oxide measurement in human spermatozoa: Flow cytometric analysis using the fluorescent probe, diaminofluorescein
-
Lampiao F, Strijdom H, Plessis SS (2006). Direct nitric oxide measurement in human spermatozoa: flow cytometric analysis using the fluorescent probe, diaminofluorescein. Int J Androl 29:564 567.
-
(2006)
Int J Androl
, vol.29
, pp. 564-567
-
-
Lampiao, F.1
Strijdom, H.2
Plessis, S.S.3
-
23
-
-
0032584177
-
Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
-
Laufs U, La Fata V, Plutzky J, Liao JK (1998). Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. Circulation 97:1129 1135.
-
(1998)
Circulation
, vol.97
, pp. 1129-1135
-
-
Laufs, U.1
La Fata, V.2
Plutzky, J.3
Liao, J.K.4
-
24
-
-
0033551539
-
Simvastatin preserves the ischemic-reperfused myocardium in normocholesterolemic rat hearts
-
Lefer AM, Campbell B, Shin YK, Scalia R, Hayward R, Lefer DJ (1999). Simvastatin preserves the ischemic-reperfused myocardium in normocholesterolemic rat hearts. Circulation 100:178 184.
-
(1999)
Circulation
, vol.100
, pp. 178-184
-
-
Lefer, A.M.1
Campbell, B.2
Shin, Y.K.3
Scalia, R.4
Hayward, R.5
Lefer, D.J.6
-
26
-
-
34247339395
-
High-density lipoprotein cholesterol regulates endothelial progenitor cells by increasing eNOS and preventing apoptosis
-
Noor R, Shuaib U, Wang CX, Todd K, Ghani U, Schwindt B et al. (2007). High-density lipoprotein cholesterol regulates endothelial progenitor cells by increasing eNOS and preventing apoptosis. Atherosclerosis 192:92 99.
-
(2007)
Atherosclerosis
, vol.192
, pp. 92-99
-
-
Noor, R.1
Shuaib, U.2
Wang, C.X.3
Todd, K.4
Ghani, U.5
Schwindt, B.6
-
27
-
-
0346729924
-
Scavenger receptor BI (SR-BI) clustered on microvillar extensions suggests that this plasma membrane domain is a way station for cholesterol trafficking between cells and high-density lipoprotein
-
Peng Y, Akmentin W, Connelly MA, Lund-Katz S, Phillips MC, Williams DL (2004). Scavenger receptor BI (SR-BI) clustered on microvillar extensions suggests that this plasma membrane domain is a way station for cholesterol trafficking between cells and high-density lipoprotein. Mol Biol Cell 15:384 396.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 384-396
-
-
Peng, Y.1
Akmentin, W.2
Connelly, M.A.3
Lund-Katz, S.4
Phillips, M.C.5
Williams, D.L.6
-
28
-
-
0026814425
-
Comparative pharmacokinetics of lovastatin, simvastatin and pravastatin in humans
-
Pentikainen PJ, Saraheimo M, Schwartz JI, Amin RD, Schwartz MS, Brunner-Ferber F et al. (1992). Comparative pharmacokinetics of lovastatin, simvastatin and pravastatin in humans. J Clin Pharmacol 32:136 140.
-
(1992)
J Clin Pharmacol
, vol.32
, pp. 136-140
-
-
Pentikainen, P.J.1
Saraheimo, M.2
Schwartz, J.I.3
Amin, R.D.4
Schwartz, M.S.5
Brunner-Ferber, F.6
-
29
-
-
0345381965
-
Statins are associated with a reduced incidence of perioperative mortality in patients undergoing major noncardiac vascular surgery
-
Poldermans D, Bax JJ, Kertai MD, Krenning B, Westerhout CM, Schinkel AF et al. (2003). Statins are associated with a reduced incidence of perioperative mortality in patients undergoing major noncardiac vascular surgery. Circulation 107:1848 1851.
-
(2003)
Circulation
, vol.107
, pp. 1848-1851
-
-
Poldermans, D.1
Bax, J.J.2
Kertai, M.D.3
Krenning, B.4
Westerhout, C.M.5
Schinkel, A.F.6
-
30
-
-
56749106312
-
Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein
-
Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM, Jr., Kastelein JJ et al. (2008). Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med 359:2195 2207.
-
(2008)
N Engl J Med
, vol.359
, pp. 2195-2207
-
-
Ridker, P.M.1
Danielson, E.2
Fonseca, F.A.3
Genest, J.4
Gotto Jr., A.M.5
Kastelein, J.J.6
-
31
-
-
0036180578
-
Role of nitric oxide/cyclic GMP in myocardial adenosine A1 receptor-inotropic response
-
Sterin-Borda L, Gomez RM, Borda E (2002). Role of nitric oxide/cyclic GMP in myocardial adenosine A1 receptor-inotropic response. Br J Pharmacol 135:444 450.
-
(2002)
Br J Pharmacol
, vol.135
, pp. 444-450
-
-
Sterin-Borda, L.1
Gomez, R.M.2
Borda, E.3
-
32
-
-
33845707278
-
Statins activate AMP-activated protein kinase in vitro and in vivo
-
Sun W, Lee TS, Zhu M, Gu C, Wang Y, Zhu Y et al. (2006). Statins activate AMP-activated protein kinase in vitro and in vivo. Circulation 114:2655 2662.
-
(2006)
Circulation
, vol.114
, pp. 2655-2662
-
-
Sun, W.1
Lee, T.S.2
Zhu, M.3
Gu, C.4
Wang, Y.5
Zhu, Y.6
-
33
-
-
0034646680
-
High density lipoprotein prevents oxidized low density lipoprotein-induced inhibition of endothelial nitric-oxide synthase localization and activation in caveolae
-
Uittenbogaard A, Shaul PW, Yuhanna IS, Blair A, Smart EJ (2000). High density lipoprotein prevents oxidized low density lipoprotein-induced inhibition of endothelial nitric-oxide synthase localization and activation in caveolae. J Biol Chem 275:11278 11283.
-
(2000)
J Biol Chem
, vol.275
, pp. 11278-11283
-
-
Uittenbogaard, A.1
Shaul, P.W.2
Yuhanna, I.S.3
Blair, A.4
Smart, E.J.5
-
34
-
-
0029983264
-
Identification, characterization, and comparison of the calmodulin-binding domains of the endothelial and inducible nitric oxide synthases
-
Venema RC, Sayegh HS, Kent JD, Harrison DG (1996). Identification, characterization, and comparison of the calmodulin-binding domains of the endothelial and inducible nitric oxide synthases. J Biol Chem 271:6435 6440.
-
(1996)
J Biol Chem
, vol.271
, pp. 6435-6440
-
-
Venema, R.C.1
Sayegh, H.S.2
Kent, J.D.3
Harrison, D.G.4
-
35
-
-
0029940418
-
U-73122, an aminosteroid phospholipase C inhibitor, may also block Ca2+ influx through phospholipase C-independent mechanism in neutrophil activation
-
Wang JP (1996). U-73122, an aminosteroid phospholipase C inhibitor, may also block Ca2+ influx through phospholipase C-independent mechanism in neutrophil activation. Naunyn Schmiedebergs Arch Pharmacol 353:599 605.
-
(1996)
Naunyn Schmiedebergs Arch Pharmacol
, vol.353
, pp. 599-605
-
-
Wang, J.P.1
-
36
-
-
18844476446
-
Rapid effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition on coronary endothelial function
-
Wassmann S, Faul A, Hennen B, Scheller B, Bohm M, Nickenig G (2003). Rapid effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition on coronary endothelial function. Circ Res 93:e98 e103.
-
(2003)
Circ Res
, vol.93
-
-
Wassmann, S.1
Faul, A.2
Hennen, B.3
Scheller, B.4
Bohm, M.5
Nickenig, G.6
-
37
-
-
33745156066
-
What the statin trials have taught us
-
Waters DD (2006). What the statin trials have taught us. Am J Cardiol 98:129 134.
-
(2006)
Am J Cardiol
, vol.98
, pp. 129-134
-
-
Waters, D.D.1
-
38
-
-
0034874686
-
Regulation of phospholipase C gamma isoforms in haematopoietic cells: Why one, not the other?
-
Wilde JI, Watson SP (2001). Regulation of phospholipase C gamma isoforms in haematopoietic cells: why one, not the other? Cell Signal 13:691 701.
-
(2001)
Cell Signal
, vol.13
, pp. 691-701
-
-
Wilde, J.I.1
Watson, S.P.2
-
39
-
-
0034006811
-
Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment
-
Yamada M, Huang Z, Dalkara T, Endres M, Laufs U, Waeber C et al. (2000). Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab 20:709 717.
-
(2000)
J Cereb Blood Flow Metab
, vol.20
, pp. 709-717
-
-
Yamada, M.1
Huang, Z.2
Dalkara, T.3
Endres, M.4
Laufs, U.5
Waeber, C.6
-
40
-
-
0034927750
-
High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase
-
Yuhanna IS, Zhu Y, Cox BE, Hahner LD, Osborne-Lawrence S, Lu P et al. (2001). High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase. Nat Med 7:853 857.
-
(2001)
Nat Med
, vol.7
, pp. 853-857
-
-
Yuhanna, I.S.1
Zhu, Y.2
Cox, B.E.3
Hahner, L.D.4
Osborne-Lawrence, S.5
Lu, P.6
|