메뉴 건너뛰기




Volumn 136, Issue 2, 2010, Pages 269-281

Human cytomegalovirus-specific CD4+ and CD8+ T-cell response determination: Comparison of short-term (24h) assays vs long-term (7-day) infected dendritic cell assay in the immunocompetent and the immunocompromised host

Author keywords

Epitopic peptide pool; Human cytomegalovirus; Immunocompetent host; Immunocompromised patients; Infected cell lysate; Infected dendritic cells; T cell response

Indexed keywords

ADULT; ARTICLE; CD4 CD8 RATIO; CELL LYSATE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; DENDRITIC CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOCOMPROMISED PATIENT; LYMPHOCYTE ACTIVATION; PRIORITY JOURNAL; RECIPIENT;

EID: 77954310031     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2010.04.008     Document Type: Article
Times cited : (9)

References (55)
  • 1
    • 0032508056 scopus 로고    scopus 로고
    • Infection in organ-transplant recipients
    • Fishman J.A., Rubin R.H. Infection in organ-transplant recipients. N. Engl. J. Med. 1998, 338:1741-1751.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 1741-1751
    • Fishman, J.A.1    Rubin, R.H.2
  • 2
    • 0002881578 scopus 로고    scopus 로고
    • Cytomegalovirus infection after bone marrow transplantation
    • Lippincott-Raven, Philadelphia, C. Paya (Ed.)
    • Boeckh M., Ljungman P. Cytomegalovirus infection after bone marrow transplantation. Transplant Infections 1998, 215-227. Lippincott-Raven, Philadelphia. C. Paya (Ed.).
    • (1998) Transplant Infections , pp. 215-227
    • Boeckh, M.1    Ljungman, P.2
  • 3
    • 33847363922 scopus 로고    scopus 로고
    • Evaluation of human cytomegalovirus DNAemia vs pp 65-antigenemia cutoff for guiding preemptive therapy in transplant recipients: a randomized study
    • Gerna G., Baldanti F., Torsellini M., et al. Evaluation of human cytomegalovirus DNAemia vs pp 65-antigenemia cutoff for guiding preemptive therapy in transplant recipients: a randomized study. Antivir. Ther. 2007, 12:63-72.
    • (2007) Antivir. Ther. , vol.12 , pp. 63-72
    • Gerna, G.1    Baldanti, F.2    Torsellini, M.3
  • 4
    • 34948871563 scopus 로고    scopus 로고
    • Use of a DNAemia cut-off for monitoring human cytomegalovirus infection reduces the number of preemptively treated children and young adults receiving hematopoietic stem cell transplantation compared with pp65-antigenemia
    • Lilleri D., Gerna G., Furione M., et al. Use of a DNAemia cut-off for monitoring human cytomegalovirus infection reduces the number of preemptively treated children and young adults receiving hematopoietic stem cell transplantation compared with pp65-antigenemia. Blood 2007, 110:2757-2760.
    • (2007) Blood , vol.110 , pp. 2757-2760
    • Lilleri, D.1    Gerna, G.2    Furione, M.3
  • 5
    • 16644369923 scopus 로고    scopus 로고
    • Cytomegalovirus
    • S10
    • Cytomegalovirus. Am. J. Transplant. 2004, 4(S10):51-58.
    • (2004) Am. J. Transplant. , vol.4 , pp. 51-58
  • 6
    • 0027455417 scopus 로고
    • Ganciclovir prophylaxis to prevent cytomegalovirus disease after allogeneic marrow transplant
    • Goodrich J.M., Bowden R.A., Fisher L., Keller C., Schoch G., Meyers J.D. Ganciclovir prophylaxis to prevent cytomegalovirus disease after allogeneic marrow transplant. Ann. Intern. Med. 1993, 118:173-178.
    • (1993) Ann. Intern. Med. , vol.118 , pp. 173-178
    • Goodrich, J.M.1    Bowden, R.A.2    Fisher, L.3    Keller, C.4    Schoch, G.5    Meyers, J.D.6
  • 7
    • 0028016207 scopus 로고
    • Human cytomegalovirus (HCMV) infection in paediatric patients given allogeneic bone marrow transplantation: role of early antiviral treatment for HCMV antigenemia on patients' outcome
    • Locatelli F., Percivalle E., Comoli P., et al. Human cytomegalovirus (HCMV) infection in paediatric patients given allogeneic bone marrow transplantation: role of early antiviral treatment for HCMV antigenemia on patients' outcome. Br. J. Haematol. 1994, 88:64-71.
    • (1994) Br. J. Haematol. , vol.88 , pp. 64-71
    • Locatelli, F.1    Percivalle, E.2    Comoli, P.3
  • 8
    • 0029800728 scopus 로고    scopus 로고
    • Cytomegalovirus pp 65 antigenemia-guided early treatment with ganciclovir versus ganciclovir at engraftment after allogeneic marrow transplantation: a randomized double-blind study
    • Boeckh M., Gooley T.A., Myerson D., Cunningham T., Schoch G., Bowden R.A. Cytomegalovirus pp 65 antigenemia-guided early treatment with ganciclovir versus ganciclovir at engraftment after allogeneic marrow transplantation: a randomized double-blind study. Blood 1996, 88:4063-4071.
    • (1996) Blood , vol.88 , pp. 4063-4071
    • Boeckh, M.1    Gooley, T.A.2    Myerson, D.3    Cunningham, T.4    Schoch, G.5    Bowden, R.A.6
  • 9
    • 33748494938 scopus 로고    scopus 로고
    • + T-cell immunity in patients receiving solid organ transplantation
    • + T-cell immunity in patients receiving solid organ transplantation. Am. J. Transplant. 2006, 6:2356-2364.
    • (2006) Am. J. Transplant. , vol.6 , pp. 2356-2364
    • Gerna, G.1    Lilleri, D.2    Fornara, C.3
  • 11
    • 40849098721 scopus 로고    scopus 로고
    • + T-cell reconstitution in adult allogeneic hematopoietic stem cell transplant recipients and immune control of viral infection
    • + T-cell reconstitution in adult allogeneic hematopoietic stem cell transplant recipients and immune control of viral infection. Haematologica 2008, 932:248-256.
    • (2008) Haematologica , vol.932 , pp. 248-256
    • Lilleri, D.1    Fornara, C.2    Chiesa, A.3    Caldera, D.4    Alessandrino, E.P.5    Gerna, G.6
  • 12
    • 0019989495 scopus 로고
    • Cytotoxic T-cells in cytomegalovirus infection: HLA-restricted T-lymphocyte and non-T-lymphocyte cytotoxic responses correlate with recovery from cytomegalovirus infection in bone-marrow-transplant recipients
    • Quinnan G.V., Kirmani N., Rook A.H., et al. Cytotoxic T-cells in cytomegalovirus infection: HLA-restricted T-lymphocyte and non-T-lymphocyte cytotoxic responses correlate with recovery from cytomegalovirus infection in bone-marrow-transplant recipients. N. Engl. J. Med. 1982, 307:7-13.
    • (1982) N. Engl. J. Med. , vol.307 , pp. 7-13
    • Quinnan, G.V.1    Kirmani, N.2    Rook, A.H.3
  • 13
    • 0025995695 scopus 로고
    • Cytotoxic T-lymphocyte response to cytomegalovirus after human allogeneic bone marrow transplantation: pattern of recovery and correlation with cytomegalovirus infection and disease
    • Reusser P., Riddell S.R., Meyers J.D., Greenberg P.D. Cytotoxic T-lymphocyte response to cytomegalovirus after human allogeneic bone marrow transplantation: pattern of recovery and correlation with cytomegalovirus infection and disease. Blood 1991, 78:1373-1380.
    • (1991) Blood , vol.78 , pp. 1373-1380
    • Reusser, P.1    Riddell, S.R.2    Meyers, J.D.3    Greenberg, P.D.4
  • 14
    • 0028353829 scopus 로고
    • Recovery of HLA-restricted cytomegalovirus (CMV)-specific T-cell responses after allogeneic bone marrow transplant: correlation with CMV disease and effect of ganciclovir prophylaxis
    • Li C.R., Greenberg P.D., Gilbert M.J., Goodrich J.M., Riddell S.R. Recovery of HLA-restricted cytomegalovirus (CMV)-specific T-cell responses after allogeneic bone marrow transplant: correlation with CMV disease and effect of ganciclovir prophylaxis. Blood 1994, 83:1971-1979.
    • (1994) Blood , vol.83 , pp. 1971-1979
    • Li, C.R.1    Greenberg, P.D.2    Gilbert, M.J.3    Goodrich, J.M.4    Riddell, S.R.5
  • 15
    • 0034699367 scopus 로고    scopus 로고
    • Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution
    • Lyons A.B. Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution. J. Immunol. Methods 2000, 243:147-154.
    • (2000) J. Immunol. Methods , vol.243 , pp. 147-154
    • Lyons, A.B.1
  • 16
    • 33947418134 scopus 로고    scopus 로고
    • Development of human cytomegalovirus-specific T-cell immunity during primary infection of pregnant women and its correlation with virus transmission to the fetus
    • Lilleri D., Fornara C., Furione M., Zavattoni M., Revello M.G., Gerna G. Development of human cytomegalovirus-specific T-cell immunity during primary infection of pregnant women and its correlation with virus transmission to the fetus. J. Infect. Dis. 2007, 195:1062-1067.
    • (2007) J. Infect. Dis. , vol.195 , pp. 1062-1067
    • Lilleri, D.1    Fornara, C.2    Furione, M.3    Zavattoni, M.4    Revello, M.G.5    Gerna, G.6
  • 17
    • 0037234038 scopus 로고    scopus 로고
    • Measuring T-cell-mediated cytotoxicity using antibody to activated caspase 3
    • Jerome K.R., Sloan D.D., Aubert M. Measuring T-cell-mediated cytotoxicity using antibody to activated caspase 3. Nat. Med. 2003, 9:4-5.
    • (2003) Nat. Med. , vol.9 , pp. 4-5
    • Jerome, K.R.1    Sloan, D.D.2    Aubert, M.3
  • 18
    • 0030891988 scopus 로고    scopus 로고
    • Determination of antigen-specific memory/effector CD4+ T cell frequencies by flow cytometry: evidence for a novel, antigen-specific homeostatic mechanism in HIV-associated immunodeficiency
    • Waldrop S.L., Pitcher C.J., Peterson D.M., Maino V.C., Picker L.J. Determination of antigen-specific memory/effector CD4+ T cell frequencies by flow cytometry: evidence for a novel, antigen-specific homeostatic mechanism in HIV-associated immunodeficiency. J. Clin. Invest. 1997, 99:1739-1750.
    • (1997) J. Clin. Invest. , vol.99 , pp. 1739-1750
    • Waldrop, S.L.1    Pitcher, C.J.2    Peterson, D.M.3    Maino, V.C.4    Picker, L.J.5
  • 19
    • 0037093102 scopus 로고    scopus 로고
    • Sensitive detection of human cytomegalovirus peptide-specific cytotoxic T-lymphocyte responses by interferon-gamma-enzyme-linked immunospot assay and flow cytometry in healthy individuals and in patients after allogeneic stem cell transplantation
    • Hebart H., Daginik S., Stevanovic S., et al. Sensitive detection of human cytomegalovirus peptide-specific cytotoxic T-lymphocyte responses by interferon-gamma-enzyme-linked immunospot assay and flow cytometry in healthy individuals and in patients after allogeneic stem cell transplantation. Blood 2002, 99:3830-3837.
    • (2002) Blood , vol.99 , pp. 3830-3837
    • Hebart, H.1    Daginik, S.2    Stevanovic, S.3
  • 20
    • 0029743737 scopus 로고    scopus 로고
    • Phenotypic analysis of antigen-specific T lymphocytes
    • Altman J.D., Moss P.A., Goulder P.J.R., et al. Phenotypic analysis of antigen-specific T lymphocytes. Science 1996, 274:94-96.
    • (1996) Science , vol.274 , pp. 94-96
    • Altman, J.D.1    Moss, P.A.2    Goulder, P.J.R.3
  • 21
    • 0031926797 scopus 로고    scopus 로고
    • T-cell epitope mapping by flow cytometry
    • Kern F., Surel I.P., Brock C., et al. T-cell epitope mapping by flow cytometry. Nat. Med. 1998, 4:975-978.
    • (1998) Nat. Med. , vol.4 , pp. 975-978
    • Kern, F.1    Surel, I.P.2    Brock, C.3
  • 23
    • 0034093051 scopus 로고    scopus 로고
    • + T cell reactivity to cytomegalovirus using protein-spanning pools of overlapping pentadecapeptides
    • + T cell reactivity to cytomegalovirus using protein-spanning pools of overlapping pentadecapeptides. Eur. J. Immunol. 2000, 30:1676-1682.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 1676-1682
    • Kern, F.1    Faulhaber, N.2    Frommel, C.3
  • 24
    • 0035452585 scopus 로고    scopus 로고
    • Use of overlapping peptide mixtures as antigens for cytokine flow cytometry
    • Maecker H.T., Dunn H.S., Suni M.A., et al. Use of overlapping peptide mixtures as antigens for cytokine flow cytometry. J. Immunol. Methods 2001, 255:27-40.
    • (2001) J. Immunol. Methods , vol.255 , pp. 27-40
    • Maecker, H.T.1    Dunn, H.S.2    Suni, M.A.3
  • 25
    • 0023230293 scopus 로고
    • Immunoaffinity purification of a 72K early antigen of human cytomegalovirus: analysis of humoral and cell-mediated immunity to the purified polypeptide
    • Rodgers B., Borysiewicz L., Mundin J., Graham S., Sissons P. Immunoaffinity purification of a 72K early antigen of human cytomegalovirus: analysis of humoral and cell-mediated immunity to the purified polypeptide. J. Gen. Virol. 1987, 68:2371-2378.
    • (1987) J. Gen. Virol. , vol.68 , pp. 2371-2378
    • Rodgers, B.1    Borysiewicz, L.2    Mundin, J.3    Graham, S.4    Sissons, P.5
  • 26
    • 0029847916 scopus 로고    scopus 로고
    • The human cytotoxic T-lymphocyte (CTL) response to human cytomegalovirus is dominated by structural protein pp 65: frequency, specificity, and T cell receptor usage of pp65-specific CTL
    • Wills M.R., Carmichael A.J., Mynard K., et al. The human cytotoxic T-lymphocyte (CTL) response to human cytomegalovirus is dominated by structural protein pp 65: frequency, specificity, and T cell receptor usage of pp65-specific CTL. J. Virol. 1996, 70:659-679.
    • (1996) J. Virol. , vol.70 , pp. 659-679
    • Wills, M.R.1    Carmichael, A.J.2    Mynard, K.3
  • 27
    • 77954309287 scopus 로고    scopus 로고
    • +-T-cell responses reactivities in healthy carriers
    • +-T-cell responses reactivities in healthy carriers. J. Virol. 2003, 77:7401-7410.
    • (2003) J. Virol. , vol.77 , pp. 7401-7410
    • Elkington, R.1    Walker, S.2    Crough, T.3
  • 28
    • 24344489044 scopus 로고    scopus 로고
    • Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects
    • Sylwester A.W., Mitchell B.L., Edgar J.B., et al. Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects. J. Exp. Med. 2005, 202:673-685.
    • (2005) J. Exp. Med. , vol.202 , pp. 673-685
    • Sylwester, A.W.1    Mitchell, B.L.2    Edgar, J.B.3
  • 29
    • 34247644028 scopus 로고    scopus 로고
    • Ex-vivo monitoring of human cytomegalovirus-specific CD8+ T-cell responses using quantiFERON®-CMV
    • Walker S., Fazou C., Crough T., et al. Ex-vivo monitoring of human cytomegalovirus-specific CD8+ T-cell responses using quantiFERON®-CMV. Transplant. Infect. Dis. 2007, 9:165-170.
    • (2007) Transplant. Infect. Dis. , vol.9 , pp. 165-170
    • Walker, S.1    Fazou, C.2    Crough, T.3
  • 30
    • 65249148542 scopus 로고    scopus 로고
    • Cell-mediated immunity to predict cytomegalovirus disease in high-risk solid organ transplant recipients
    • Kumar D., Chernenko S., Moussa G., et al. Cell-mediated immunity to predict cytomegalovirus disease in high-risk solid organ transplant recipients. Am. J. Transplant. 2009, 9:1214-1222.
    • (2009) Am. J. Transplant. , vol.9 , pp. 1214-1222
    • Kumar, D.1    Chernenko, S.2    Moussa, G.3
  • 33
    • 20844437647 scopus 로고    scopus 로고
    • + T cells by a novel method using monocyte-derived HCMV-infected immature dendritic cells
    • + T cells by a novel method using monocyte-derived HCMV-infected immature dendritic cells. Eur. J. Immunol. 2005, 35:1795-1804.
    • (2005) Eur. J. Immunol. , vol.35 , pp. 1795-1804
    • Lozza, L.1    Lilleri, D.2    Percivalle, E.3
  • 34
    • 34447134842 scopus 로고    scopus 로고
    • Inconsistent responses of cytomegalovirus-specific T-cells to pp 65 and IE-1 vs infected dendritic cells in organ transplant recipients
    • Lilleri D., Zelini P., Fornara C., Comolli G., Gerna G. Inconsistent responses of cytomegalovirus-specific T-cells to pp 65 and IE-1 vs infected dendritic cells in organ transplant recipients. Am. J. Transplant. 2007, 7:1997-2005.
    • (2007) Am. J. Transplant. , vol.7 , pp. 1997-2005
    • Lilleri, D.1    Zelini, P.2    Fornara, C.3    Comolli, G.4    Gerna, G.5
  • 36
    • 0034782157 scopus 로고    scopus 로고
    • Extracorporeal photochemotherapy for treatment of acute and chronic GvHD in childhood
    • Salvaneschi L., Perotti C., Zecca M., et al. Extracorporeal photochemotherapy for treatment of acute and chronic GvHD in childhood. Transfusion 2001, 41:1299-1305.
    • (2001) Transfusion , vol.41 , pp. 1299-1305
    • Salvaneschi, L.1    Perotti, C.2    Zecca, M.3
  • 37
    • 0037090071 scopus 로고    scopus 로고
    • Definition of HCMV infection and disease in transplant recipients
    • Ljungman P., Griffiths P., Paya C. Definition of HCMV infection and disease in transplant recipients. Clin. Infect. Dis. 2002, 34:1094-1097.
    • (2002) Clin. Infect. Dis. , vol.34 , pp. 1094-1097
    • Ljungman, P.1    Griffiths, P.2    Paya, C.3
  • 38
    • 33644662479 scopus 로고    scopus 로고
    • Impact of human metapneumovirus and human cytomegalovirus versus other respiratory viruses on the lower respiratory tract infections of lung transplant recipients
    • Gerna G., Vitulo P., Rovida F., et al. Impact of human metapneumovirus and human cytomegalovirus versus other respiratory viruses on the lower respiratory tract infections of lung transplant recipients. J. Med. Virol. 2006, 78:408-416.
    • (2006) J. Med. Virol. , vol.78 , pp. 408-416
    • Gerna, G.1    Vitulo, P.2    Rovida, F.3
  • 39
    • 77954310522 scopus 로고    scopus 로고
    • Erratum
    • Erratum. J. Med. Virol. 2008, 80:1869.
    • (2008) J. Med. Virol. , vol.80 , pp. 1869
  • 40
    • 65249100197 scopus 로고    scopus 로고
    • Preemptive therapy of systemic and pulmonary human cytomegalovirus infection in lung transplant recipients
    • Gerna G., Lilleri D., Rognoni V., et al. Preemptive therapy of systemic and pulmonary human cytomegalovirus infection in lung transplant recipients. Am. J. Transplant. 2009, 9:1142-1150.
    • (2009) Am. J. Transplant. , vol.9 , pp. 1142-1150
    • Gerna, G.1    Lilleri, D.2    Rognoni, V.3
  • 41
    • 0028289244 scopus 로고
    • Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
    • Sallusto F., Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J. Exp. Med. 1994, 179:1109-1118.
    • (1994) J. Exp. Med. , vol.179 , pp. 1109-1118
    • Sallusto, F.1    Lanzavecchia, A.2
  • 42
    • 65649089024 scopus 로고    scopus 로고
    • Human cytomegalovirus-specific T-cell reconstitution in young patients receiving T-cell-depleted, allogeneic hematopoietic stem cell transplantation
    • Lilleri D., Gerna G., Fornara C., et al. Human cytomegalovirus-specific T-cell reconstitution in young patients receiving T-cell-depleted, allogeneic hematopoietic stem cell transplantation. J. Infect. Dis. 2009, 199:829-836.
    • (2009) J. Infect. Dis. , vol.199 , pp. 829-836
    • Lilleri, D.1    Gerna, G.2    Fornara, C.3
  • 44
    • 18744436552 scopus 로고    scopus 로고
    • Dense bodies of human cytomegalovirus induce both humoral and cellular immune responses in the absence of viral gene expression
    • Pepperl S., Münster J., Mach M., Harris J.R., Plachter B. Dense bodies of human cytomegalovirus induce both humoral and cellular immune responses in the absence of viral gene expression. J. Virol. 2000, 74:6132-6146.
    • (2000) J. Virol. , vol.74 , pp. 6132-6146
    • Pepperl, S.1    Münster, J.2    Mach, M.3    Harris, J.R.4    Plachter, B.5
  • 45
    • 20244377843 scopus 로고    scopus 로고
    • Protection from cytomegalovirus after transplantation is correlated with immediate early 1-specific CD8 T cells
    • Bunde T., Kirchner A., Hoffmeister B., et al. Protection from cytomegalovirus after transplantation is correlated with immediate early 1-specific CD8 T cells. J. Exp. Med. 2005, 201:1031-1036.
    • (2005) J. Exp. Med. , vol.201 , pp. 1031-1036
    • Bunde, T.1    Kirchner, A.2    Hoffmeister, B.3
  • 46
    • 33847031357 scopus 로고    scopus 로고
    • Longitudinal assessment of cytomegalovirus (CMV)-specific immune responses in liver transplant recipients at high risk for late CMV disease
    • La Rosa C., Limaye A.P., Krishnan A., Longmate J., Diamond D.J. Longitudinal assessment of cytomegalovirus (CMV)-specific immune responses in liver transplant recipients at high risk for late CMV disease. J. Infect. Dis. 2007, 195:633-644.
    • (2007) J. Infect. Dis. , vol.195 , pp. 633-644
    • La Rosa, C.1    Limaye, A.P.2    Krishnan, A.3    Longmate, J.4    Diamond, D.J.5
  • 47
    • 47549106346 scopus 로고    scopus 로고
    • Monitoring cytomegalovirus IE-1 and pp 65-specific CD4+ and CD8+ T-cell responses after allogeneic stem cell transplantation may identify patients at risk for recurrent CMV reactivations
    • Gratama J.W., Brooimans R.A., van der Holt B., et al. Monitoring cytomegalovirus IE-1 and pp 65-specific CD4+ and CD8+ T-cell responses after allogeneic stem cell transplantation may identify patients at risk for recurrent CMV reactivations. Cytometry B 2008, 74B:211-220.
    • (2008) Cytometry B , vol.74 B , pp. 211-220
    • Gratama, J.W.1    Brooimans, R.A.2    van der Holt, B.3
  • 48
    • 53749098854 scopus 로고    scopus 로고
    • + T cells and control of HCMV replication after allogeneic stem cell transplantation
    • + T cells and control of HCMV replication after allogeneic stem cell transplantation. J. Virol. 2008, 82:10143-10152.
    • (2008) J. Virol. , vol.82 , pp. 10143-10152
    • Sacre, K.1    Nguyen, S.2    Deback, C.3
  • 49
    • 48249089602 scopus 로고    scopus 로고
    • Dissection of the CMV specific T-cell response is required for optimized cardiac transplant monitoring
    • Kirchner A., Hoffmeister B., Cherepnev-G G., et al. Dissection of the CMV specific T-cell response is required for optimized cardiac transplant monitoring. J. Med. Virol. 2008, 80:1604-1614.
    • (2008) J. Med. Virol. , vol.80 , pp. 1604-1614
    • Kirchner, A.1    Hoffmeister, B.2    Cherepnev-G, G.3
  • 50
    • 55949127402 scopus 로고    scopus 로고
    • Polyfunctional cytomegalovirus-specific CD4+ and pp 65 CD8+ T cells protect against high-level replication after liver transplantation
    • Nebbia G., Mattes F.M., Smith C., et al. Polyfunctional cytomegalovirus-specific CD4+ and pp 65 CD8+ T cells protect against high-level replication after liver transplantation. Am. J. Transplant. 2008, 8:2590-2599.
    • (2008) Am. J. Transplant. , vol.8 , pp. 2590-2599
    • Nebbia, G.1    Mattes, F.M.2    Smith, C.3
  • 51
    • 20044380510 scopus 로고    scopus 로고
    • + cell populations with divergent functionality in hematopoietic stem-cell transplant recipients
    • + cell populations with divergent functionality in hematopoietic stem-cell transplant recipients. J. Infect. Dis. 2005, 191:977-984.
    • (2005) J. Infect. Dis. , vol.191 , pp. 977-984
    • Lacey, S.F.1    Martinez, J.2    Gallez-Hawkins, G.3
  • 52
    • 33750710780 scopus 로고    scopus 로고
    • Functional comparison of T cells recognizing cytomegalovirus pp 65 and immediate-early antigen polypeptides in hematopoietic stem-cell transplant and solid organ transplant recipients
    • Lacey S.F., La Rosa C., Zhou W., et al. Functional comparison of T cells recognizing cytomegalovirus pp 65 and immediate-early antigen polypeptides in hematopoietic stem-cell transplant and solid organ transplant recipients. J. Infect. Dis. 2006, 194:1410-1421.
    • (2006) J. Infect. Dis. , vol.194 , pp. 1410-1421
    • Lacey, S.F.1    La Rosa, C.2    Zhou, W.3
  • 53
    • 0032850575 scopus 로고    scopus 로고
    • + T-cell response to human cytomegalovirus: the 72-kilodalton major immediate-early protein revisited
    • + T-cell response to human cytomegalovirus: the 72-kilodalton major immediate-early protein revisited. J. Virol. 1999, 73:8179-8184.
    • (1999) J. Virol. , vol.73 , pp. 8179-8184
    • Kern, F.1    Surel, I.P.2    Faulhaber, N.3
  • 54
    • 0008120151 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte (CTL) responses to human cytomegalovirus pp 65, IE1-Exon4, gB, pp150, and pp28 in healthy individuals: reevaluation of prevalence of IE1-specific CTLs
    • Gyulai Z., Endresz V., Burian K., et al. Cytotoxic T lymphocyte (CTL) responses to human cytomegalovirus pp 65, IE1-Exon4, gB, pp150, and pp28 in healthy individuals: reevaluation of prevalence of IE1-specific CTLs. J. Infect. Dis. 2000, 181:1537-1546.
    • (2000) J. Infect. Dis. , vol.181 , pp. 1537-1546
    • Gyulai, Z.1    Endresz, V.2    Burian, K.3
  • 55
    • 20544466061 scopus 로고    scopus 로고
    • Differences in CMV-specific T-cell levels and long-term susceptibility to CMV infection after kidney, heart and lung transplantation
    • Sester U., Gartner B.C., Wilkens H., et al. Differences in CMV-specific T-cell levels and long-term susceptibility to CMV infection after kidney, heart and lung transplantation. Am. J. Transplant. 2005, 5:1483-1489.
    • (2005) Am. J. Transplant. , vol.5 , pp. 1483-1489
    • Sester, U.1    Gartner, B.C.2    Wilkens, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.