Highly enhanced cytotoxicity of a dimeric bispecific diabody, the hEx3 tetrabody

Journal of Biological Chemistry

Volumn 285, Issue 27, 2010, Pages 20844-20849

  Asano, Ryutaro ^a   Ikoma, Keiko ^a   Sone, Yukiko ^a   Kawaguchi, Hiroko ^a   Taki, Shintaro ^a   Hayashi, Hiroki ^b   Nakanishi, Takeshi ^a   Umetsu, Mitsuo ^a   Katayose, Yu ^b   Unno, Michiaki ^b   Kudo, Toshio ^a   Kumagai, Izumi ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROLIFERATION; DISEASES; LIGHT SCATTERING; THERMOANALYSIS;

BINDING ACTIVITIES; CANCER CELL GROWTH; CANCER IMMUNOTHERAPY; EPIDERMAL GROWTH FACTOR RECEPTORS; STATIC LIGHT SCATTERING; STOICHIOMETRIC BINDING; THERAPEUTIC ANTIBODIES; THERMO DYNAMIC ANALYSIS;

OLIGOMERS;

ANTINEOPLASTIC AGENT; BISPECIFIC ANTIBODY; DIMER; HEX3 ANTIBODY; RECOMBINANT ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; TETRAMER; UNCLASSIFIED DRUG;

ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CONTROLLED STUDY; DRUG BINDING; DRUG CYTOTOXICITY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; PRIORITY JOURNAL; STOICHIOMETRY; THERMODYNAMICS;

EID: 77954221573     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.120444     Document Type: Article

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