Probing the recognition surface of a DNA triplex: Binding studies with intercalator-neomycin conjugates

Biochemistry

Volumn 49, Issue 26, 2010, Pages 5540-5552

  Xue, Liang ^a   Xi, Hongjuan ^a   Kumar, Sunil ^a   Gray, David ^a   Davis, Erik ^a   Hamilton, Paris ^a   Skriba, Michael ^a   Arya, Dev P ^a  

^a CLEMSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING AFFINITIES; BINDING CONSTANT; BINDING STUDIES; CIRCULAR DICHROISM; DISPLACEMENT ASSAY; HOFF EQUATION; INTERCALATORS; ISOTHERMAL TITRATION CALORIMETRY; LOW CONCENTRATIONS; NAPHTHALENE DIIMIDE; PARENT COMPOUNDS; POLYNUCLEOTIDES; SURFACE AREA; THERMODYNAMIC PARAMETER; THERMODYNAMIC STUDIES; UV MELTING;

BINDING ENERGY; DIALYSIS; DICHROISM; DIFFERENTIAL SCANNING CALORIMETRY; DNA; EXPERIMENTS; GENES; KETONES; NAPHTHALENE; NUCLEIC ACIDS; THERMODYNAMICS; TITRATION;

ANTIBIOTICS;

ANTHRAQUINONE; ANTHRAQUINONE NEOMYCIN CONJUGATE; BENZOQUINOQUINOXALINE NEOMYCIN CONJUGATE; INTERCALATING AGENT; NAPHTHALENE DIIMIDE NEOMYCIN CONJUGATE; NEOMYCIN; NEOMYCIN PYRENE CONJUGATE; POLY(DEOXYADENYLATE DEOXYTHYMIDYLATE); UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CIRCULAR DICHROISM; CONTROLLED STUDY; DENATURATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BINDING; ISOTHERMAL TITRATION CALORIMETRY; PRIORITY JOURNAL; TEMPERATURE; THERMODYNAMICS;

BINDING SITES; CIRCULAR DICHROISM; DNA; INTERCALATING AGENTS; NEOMYCIN; NUCLEIC ACID CONFORMATION; NUCLEIC ACID DENATURATION; POLY A; POLY T; THERMODYNAMICS;

EID: 77954195336     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100071j     Document Type: Article

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