Determination of metoprolol in human plasma and urine by high-performance liquid chromatography with fluorescence detection

Journal of Separation Science

Volumn 33, Issue 13, 2010, Pages 1904-1908

  Yilmaz, Bilal ^a   Asci, Ali ^a   Arslan, Sakir ^b  

^a ATATÜRK UNIVERSITY   (Turkey)

^b ATATURK UNIVERSITY   (Turkey)

Author keywords

HPLC; Liquid liquid extraction; Metoprolol; Pharmacokinetic study; Validation

Indexed keywords

ATENOLOL; CONCENTRATION RANGES; EXTRACTION RECOVERY; FLUORESCENCE DETECTION; HPLC METHOD; HUMAN PLASMAS; INTERNAL STANDARDS; LIQUID-LIQUID EXTRACTION; METHANOL-WATER; METOPROLOL; MOBILE PHASE; PHARMACOKINETIC STUDIES;

BODY FLUIDS; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHANOL; PHARMACOKINETICS; PLASMA (HUMAN); PLASMAS; POLYMORPHISM; SOLVENT EXTRACTION;

LIQUIDS;

ATENOLOL; METHANOL; METOPROLOL TARTRATE; PROBLOK; UNCLASSIFIED DRUG; WATER; METOPROLOL;

ANALYTICAL EQUIPMENT; AREA UNDER THE CURVE; ARTICLE; CASE REPORT; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG STABILITY; DRUG URINE LEVEL; FLUORESCENCE ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYPERTENSION; MAXIMUM PLASMA CONCENTRATION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; TIME TO MAXIMUM PLASMA CONCENTRATION; ADULT; BLOOD; CALIBRATION; CHEMICAL STRUCTURE; FLUORESCENCE; SENSITIVITY AND SPECIFICITY; STANDARD; STATISTICAL MODEL; URINE;

ADULT; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLUORESCENCE; HUMANS; LINEAR MODELS; METOPROLOL; MOLECULAR STRUCTURE; REFERENCE STANDARDS; SENSITIVITY AND SPECIFICITY;

EID: 77954153363     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201000136     Document Type: Article

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