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Volumn 55, Issue 1-2, 2002, Pages 81-85
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Determination of metoprolol enantiomers in human urine by GC-MS using (-)-α-methoxy-α-(trifluoromethyl)phenylacetyl chloride as a chiral derivatizing agent
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Author keywords
Chiral separation; Derivatization; Gas chromatography mass spectrometry; Metoprolol; Urine samples
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Indexed keywords
ACETAMIDE DERIVATIVE;
ALPHA METHOXY ALPHA (TRIFLUOROMETHYL)PHENYLACETYLCHLORIDE;
AMIDE;
METOPROLOL TARTRATE;
N METHYL N (TRIMETHYLSILYL)TRIFLUOROACETAMIDE;
REAGENT;
SILANE DERIVATIVE;
UNCLASSIFIED DRUG;
ANALYTIC METHOD;
ARTICLE;
CHIRALITY;
CONTROLLED STUDY;
DERIVATIZATION;
DIASTEREOISOMER;
DRUG DETERMINATION;
DRUG PURIFICATION;
ENANTIOMER;
GAS CHROMATOGRAPHY;
HUMAN;
LIQUID LIQUID EXTRACTION;
MASS SPECTROMETRY;
NORMAL HUMAN;
PRIORITY JOURNAL;
QUANTITATIVE ASSAY;
RACEMIC MIXTURE;
REACTION TIME;
URINALYSIS;
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EID: 0036150310
PISSN: 00095893
EISSN: None
Source Type: Journal
DOI: 10.1007/BF02492319 Document Type: Article |
Times cited : (23)
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References (11)
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